temozolomide has been researched along with Bone Marrow Diseases in 4 studies
Bone Marrow Diseases: Diseases involving the BONE MARROW.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Temozolomide (TMZ) is, in combination with radiotherapy (RT), the treatment of choice for glioblastoma multiforme." | 3.83 | Persistent bone marrow depression following short-term treatment with temozolomide. ( Brandal, P; Johannesen, TB; Tjønnfjord, GE; Vandraas, K, 2016) |
| "Temozolomide is an alkylating agent used frequently in the management of gliomas." | 2.44 | Prolonged and severe myelosuppression in two patients after low-dose temozolomide treatment- case study and review of literature. ( Brown, MP; Selva-Nayagam, S; Singhal, N, 2007) |
| "Three human colon cancer cell lines were used, SW480 cells, which are wild-type for mismatch repair genes and have mutated p53, HCT116 cells, which are mutant in hMLH1 and wild-type for p53, and HCT15 cells, which are mutant in hMSH6 and mutant in p53 as well." | 1.31 | Base excision repair as a therapeutic target in colon cancer. ( Gerson, SL; Liu, L; Nakatsuru, Y, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vandraas, K | 1 |
| Tjønnfjord, GE | 1 |
| Johannesen, TB | 1 |
| Brandal, P | 1 |
| Bedikian, AY | 1 |
| Papadopoulos, NE | 1 |
| Kim, KB | 1 |
| Hwu, WJ | 1 |
| Homsi, J | 1 |
| Glass, MR | 1 |
| Cain, S | 1 |
| Rudewicz, P | 1 |
| Vernillet, L | 1 |
| Hwu, P | 1 |
| Liu, L | 1 |
| Nakatsuru, Y | 1 |
| Gerson, SL | 1 |
| Singhal, N | 1 |
| Selva-Nayagam, S | 1 |
| Brown, MP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I/II Trial of TRC102 (Methoxyamine HCl) in Combination With Temozolomide in Patients With Relapsed Solid Tumors and Lymphomas[NCT01851369] | Phase 1/Phase 2 | 93 participants (Actual) | Interventional | 2013-07-12 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for temozolomide and Bone Marrow Diseases
| Article | Year |
|---|---|
Prolonged and severe myelosuppression in two patients after low-dose temozolomide treatment- case study and review of literature.
Topics: Antineoplastic Agents, Alkylating; Bone Marrow; Bone Marrow Diseases; Brain Neoplasms; Cranial Irrad | 2007 |
1 trial available for temozolomide and Bone Marrow Diseases
| Article | Year |
|---|---|
A phase IB trial of intravenous INO-1001 plus oral temozolomide in subjects with unresectable stage-III or IV melanoma.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Ch | 2009 |
2 other studies available for temozolomide and Bone Marrow Diseases
| Article | Year |
|---|---|
Persistent bone marrow depression following short-term treatment with temozolomide.
Topics: Aged; Anemia, Aplastic; Bone Marrow Diseases; Bone Marrow Failure Disorders; Brain Neoplasms; Dacarb | 2016 |
Base excision repair as a therapeutic target in colon cancer.
Topics: Animals; Antineoplastic Agents, Alkylating; Base Pair Mismatch; Bone Marrow Diseases; Chromosome Abe | 2002 |