Page last updated: 2024-11-04

temozolomide and Astroblastoma

temozolomide has been researched along with Astroblastoma in 31 studies

Research Excerpts

ExcerptRelevanceReference
"Genotyping of putative determinants of temozolomide (TMZ)-induced life-threatening bone marrow suppression was performed in two patients with glioma treated with adjuvant TMZ and radiation therapy."3.77Temozolomide-induced severe myelosuppression: analysis of clinically associated polymorphisms in two patients. ( Berg, A; Kolesar, J; Mehta, M; Petrich, RJ; Steen, P; Sylvester, RK; Tate, JM, 2011)
"Because of the diffuse nature of gliomatosis cerebri (GC), surgery is not suitable, and large field radiotherapy carries the risk of severe toxicity."2.71Initial chemotherapy in gliomatosis cerebri. ( Carpentier, A; Cartalat-Carel, S; Chinot, O; Cougnard, J; Delattre, JY; Djafari, L; Duffau, H; Gervais, H; Hoang-Xuan, K; Honnorat, J; Laigle, F; Mokhtari, K; Napolitano, M; Sanson, M; Taillandier, L; Taillibert, S, 2004)
"The optimal therapy for gliomatosis cerebri is unclear, and the rate of response to chemotherapy is not known."2.71Chemotherapy as initial treatment in gliomatosis cerebri: results with temozolomide. ( Gomori, JM; Levin, N; Siegal, T, 2004)
"Dysembryoplastic neuroepithelial tumors (DNETs) are low-grade neuroglial tumors that are traditionally considered to be benign hamartoma-like mass lesions."1.43Radiologic response to radiation therapy concurrent with temozolomide for progressive simple dysembryoplastic neuroepithelial tumor. ( Fenstermaker, RA; Mechtler, LL; Morr, S; Prasad, D; Qiu, J, 2016)
"Clinical presentation of gliomatosis cerebri is variable and depends on the degree, extent, and location of cortical involvement."1.39Bilateral ptosis as initial presentation of gliomatosis cerebri: case report. ( Braca, J; Kovanda, T; Prabhu, V, 2013)
"Gliomatosis cerebri is a rare primary cerebral tumour entity characterized by diffuse infiltrative growth patterns representing a WHO grade III malignancy."1.35First experiences with low-dose anti-angiogenic treatment in gliomatosis cerebri with signs of angiogenic activity. ( Brockmann, MA; Hermes, P; Kohlhof, P; Neumaier-Probst, E; Schmieder, K; Seiz, M; Tuettenberg, J; Vajkoczy, P; VON Deimling, A, 2009)
"Astroblastoma is a historically traded microscopic diagnosis to denote a rare neuroepithelial tumor of uncertain nosology, involving a distinctive pattern of pseudorosette arrangement of neoplastic cells."1.35Astroblastoma with rhabdoid features and favorable long-term outcome: report of a case with a 12-year follow-up. ( El-Koussy, M; Fathi, AR; Kappeler, A; Mariani, L; Novoa, E; Vajtai, I, 2008)
"Temozolomide has shown antineoplastic activity against malignant gliomas and more recently was beneficial in one patient with gliomatosis cerebri."1.32Gliomatosis cerebri: clinical, neurochemical and neuroradiological response to temozolomide administration. ( Ambrosetto, P; Barbiroli, B; Cortelli, P; Crinò, L; Franceschi, E; Lodi, R; Setola, E; Tonon, C, 2003)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (38.71)29.6817
2010's14 (45.16)24.3611
2020's5 (16.13)2.80

Authors

AuthorsStudies
Gonda, T1
Wakabayashi, K1
Haraguchi, K1
Arai, Y1
Oyama, H1
Sarper, B1
Yaprak Bayrak, B1
Halis, H1
Alparslan, B1
Yeni Bayraktar, H1
Kuo, C1
Foon, D1
Waters, K1
Cheung, C1
Margol, AS1
Nakano, Y1
Yamasaki, K2
Satomi, K1
Fukushima, H1
Okuhiro, Y1
Okada, K1
Osugi, Y1
Sakamoto, H1
Inoue, T2
Yoshida, A1
Ichimura, K1
Hara, J1
Bale, TA1
Sait, SF1
Benhamida, J1
Ptashkin, R1
Haque, S1
Villafania, L1
Sill, M1
Sadowska, J1
Akhtar, RB1
Liechty, B1
Juthani, R1
Ladanyi, M1
Fowkes, M1
Karajannis, MA1
Rosenblum, MK1
Carroll, KT1
Hirshman, B1
Ali, MA1
Alattar, AA1
Brandel, MG1
Lochte, B1
Lanman, T1
Carter, B1
Chen, CC1
Zhang, J1
Xiao, X1
Zhu, J2
Gao, Z1
Lai, X2
Zhu, X2
Mao, G1
Autran, D1
Barrie, M1
Matta, M1
Monserrat, C1
Campello, C1
Petrirena, G1
Boucard, C1
Padovani, L1
Loundou, A1
Appay, R1
Graillon, T1
Dufour, H1
Figarella-Branger, D1
Chinot, O2
Tabouret, E1
Kovanda, T1
Braca, J1
Prabhu, V1
Yokogami, K1
Ohta, H1
Yamashita, S1
Uehara, H1
Sato, Y1
Takeshima, H1
Bertero, L1
Cassoni, P1
Rudà, R1
Chen, Z1
Song, S1
Morr, S1
Qiu, J1
Prasad, D1
Mechtler, LL1
Fenstermaker, RA1
Jicha, GA1
Glantz, J1
Clarke, MJ1
Lehwald, LM1
Russo, DP1
Giannini, C1
Wald, JT1
Uhm, J1
Kumar, N1
Aksamit, AJ1
Wetmore, CJ1
Seiz, M1
Kohlhof, P1
Brockmann, MA1
Neumaier-Probst, E1
Hermes, P1
VON Deimling, A1
Vajkoczy, P1
Schmieder, K1
Tuettenberg, J1
Kong, DS1
Kim, ST1
Lee, JI1
Suh, YL1
Lim, DH1
Kim, WS1
Kwon, KH1
Park, K1
Kim, JH1
Nam, DH1
Sylvester, RK1
Steen, P1
Tate, JM1
Mehta, M1
Petrich, RJ1
Berg, A1
Kolesar, J1
Kumabe, T1
Kanamori, M1
Sonoda, Y1
Watanabe, M1
Tominaga, T1
Chadarévian, JP1
Legido, A1
Halligan, GE1
Faerber, EN1
Piatt, JH1
Morrissette, JD1
Ara, J1
Grant, ML1
Katsetos, CD1
Hansen, N1
Wittig, A1
Hense, J1
Kastrup, O1
Gizewski, ER1
Van de Nes, JA1
Mattox, AK1
Lark, AL1
Adamson, DC1
Hargrave, D1
Bouffet, E2
Gammon, J1
Becker, L1
Rutka, J1
Baruchel, S1
Lodi, R1
Setola, E1
Tonon, C1
Ambrosetto, P1
Franceschi, E1
Crinò, L1
Barbiroli, B1
Cortelli, P1
Chamberlain, MC1
Sanson, M2
Cartalat-Carel, S1
Taillibert, S1
Napolitano, M1
Djafari, L1
Cougnard, J1
Gervais, H1
Laigle, F1
Carpentier, A1
Mokhtari, K2
Taillandier, L1
Duffau, H1
Honnorat, J1
Hoang-Xuan, K2
Delattre, JY2
Levin, N1
Gomori, JM1
Siegal, T1
Piccirilli, M1
Landi, A1
Salvati, M1
Terasaki, M1
Katsuki, H1
Fukushima, S1
Shigemori, M1
Fathi, AR1
Novoa, E1
El-Koussy, M1
Kappeler, A1
Mariani, L1
Vajtai, I1
Kaloshi, G1
Everhard, S1
Laigle-Donadey, F1
Marie, Y1
Navarro, S1
Idbaih, A1
Ducray, F1
Thillet, J1
Benjelloun, A1
Delavelle, J1
Lazeyras, F1
Dietrich, PY1

Reviews

2 reviews available for temozolomide and Astroblastoma

ArticleYear
Cerebellar gliomatosis in a toddler: case report of a challenging condition and review of the literature.
    Journal of child neurology, 2012, Volume: 27, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Cerebellar Neoplasms; Cerebellum; Child, Preschool; Dacarbazine;

2012
Marked response of gliomatosis cerebri to temozolomide and whole brain radiotherapy.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool

2012

Trials

5 trials available for temozolomide and Astroblastoma

ArticleYear
Impact of adjuvant chemotherapy for gliomatosis cerebri.
    BMC cancer, 2010, Aug-13, Volume: 10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

2010
Initial chemotherapy in gliomatosis cerebri.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2004
Chemotherapy as initial treatment in gliomatosis cerebri: results with temozolomide.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Combined Modalit

2004
Pilot trial of the rate of response, safety, and tolerability of temozolomide and oral VP-16 in patients with recurrent or treatment-induced malignant central nervous system tumors.
    Surgical neurology, 2008, Volume: 69, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine;

2008
Genetic markers predictive of chemosensitivity and outcome in gliomatosis cerebri.
    Neurology, 2008, Feb-19, Volume: 70, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Chromosome Mapping; C

2008

Other Studies

24 other studies available for temozolomide and Astroblastoma

ArticleYear
[Primary leptomeningeal gliomatosis treated with temozolomide: a case report].
    Rinsho shinkeigaku = Clinical neurology, 2021, Dec-22, Volume: 61, Issue:12

    Topics: Adult; Humans; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Meninges; Neoplasms, Neuroepit

2021
Malignant Astroblastoma
    Balkan medical journal, 2020, 06-01, Volume: 37, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Bevacizumab; Headache; Huma

2020
Central diabetes insipidus: A rare unreported side effect of temozolomide in pediatrics.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Diabetes Insipidus, Neurogenic; Humans; M

2020
A case of pediatric gliomatosis cerebri harboring H3F3A K27 mutation.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Female; Histones; Humans; Magnetic Resona

2020
Malignant transformation of a polymorphous low grade neuroepithelial tumor of the young (PLNTY).
    Acta neuropathologica, 2021, Volume: 141, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Chemoradiotherapy; Fema

2021
Management and Survival Patterns of Patients with Gliomatosis Cerebri: A SEER-Based Analysis.
    World neurosurgery, 2017, Volume: 103

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain N

2017
Lactoferrin- and RGD-comodified, temozolomide and vincristine-coloaded nanostructured lipid carriers for gliomatosis cerebri combination therapy.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Dacarbaz

2018
Leptomeningeal Gliomatosis: A Single Institution Study of 31 Patients.
    Anticancer research, 2019, Volume: 39, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2019
Bilateral ptosis as initial presentation of gliomatosis cerebri: case report.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2013, Volume: 74 Suppl 1

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Blepharoptosis; Brain Neoplasms; Chemoradiothera

2013
Case of primary diffuse leptomeningeal gliomatosis.
    Brain tumor pathology, 2014, Volume: 31, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Fat

2014
Nocardia abscesses mimicking tumor progression in gliomatosis cerebri responding to temozolomide.
    Journal of neuro-oncology, 2015, Volume: 121, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain; Brain Abscess; Brain Neoplasms; Dacarbazine; Humans;

2015
Nanostructured lipid carriers based temozolomide and gene co-encapsulated nanomedicine for gliomatosis cerebri combination therapy.
    Drug delivery, 2016, Volume: 23, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Dacarbazine; DNA; Drug

2016
Radiologic response to radiation therapy concurrent with temozolomide for progressive simple dysembryoplastic neuroepithelial tumor.
    Acta neurochirurgica, 2016, Volume: 158, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Neop

2016
Primary diffuse leptomeningeal gliomatosis.
    European neurology, 2009, Volume: 62, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain; Dacarbazine; Diagnosis, Differential; Humans;

2009
First experiences with low-dose anti-angiogenic treatment in gliomatosis cerebri with signs of angiogenic activity.
    Anticancer research, 2009, Volume: 29, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Cell Proliferation; Cyclooxy

2009
Temozolomide-induced severe myelosuppression: analysis of clinically associated polymorphisms in two patients.
    Anti-cancer drugs, 2011, Volume: 22, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B; ATP Binding

2011
Prognostic factors for patients with gliomatosis cerebri: retrospective analysis of 17 consecutive cases.
    Neurosurgical review, 2010, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy; Brain Neo

2010
Long survival of primary diffuse leptomeningeal gliomatosis following radiotherapy and temozolomide: case report and literature review.
    European journal of medical research, 2011, Sep-12, Volume: 16, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Chemoradiotherapy; Dacarbazine; Humans; Male; Meningeal Neoplasms

2011
Response to low dose temozolomide in radiation induced gliomatosis cerebri.
    Medical and pediatric oncology, 2003, Volume: 41, Issue:6

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Leukemi

2003
Gliomatosis cerebri: clinical, neurochemical and neuroradiological response to temozolomide administration.
    Magnetic resonance imaging, 2003, Volume: 21, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Humans; Magnetic Resonance I

2003
Gliomatosis cerebri: better definition, better treatment.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Astrocyt

2004
Gliomatosis cerebri treatment in 11 elderly patients.
    Journal of experimental & clinical cancer research : CR, 2006, Volume: 25, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined M

2006
Astroblastoma with rhabdoid features and favorable long-term outcome: report of a case with a 12-year follow-up.
    Pathology, research and practice, 2008, Volume: 204, Issue:5

    Topics: Antibodies, Antinuclear; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2008
Possible efficacy of temozolomide in a patient with gliomatosis cerebri.
    Neurology, 2001, Nov-27, Volume: 57, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Humans; Magnetic Reso

2001