temozolomide has been researched along with Angiogenesis, Pathologic in 57 studies
Excerpt | Relevance | Reference |
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"Thirty rats with glioma were divided into control group, temozolomide (TMZ) group (TMZ 30 mg/kg once daily for 5 day), and TMZ plus Caffeine group (TMZ 30 mg/kg once daily for 5 day and caffeine 100 mg/kg once daily for 2 weeks)." | 8.12 | Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats. ( Chen, JC; Hwang, JH, 2022) |
" Therefore, we aimed to examine the Synergistic effects of Gefitinib (GFI) in combination with Temozolomide on VEGF and MMPs in glioma cell line (U87MG)." | 8.12 | Synergistic Effect of Gefitinib and Temozolomide on U87MG Glioblastoma Angiogenesis. ( Hossienpour, M; Karami, A; Kiani, A; Mohammadi Noori, E; Najafi, K; Rahpyma, M, 2022) |
" The aim of this study was to clarify whether PET with C-methyl-L-methionine (MET-PET) would supplement MRI assessing of response after initiating BEV in glioblastoma." | 7.83 | MRI and 11C-methyl-L-methionine PET Differentiate Bevacizumab True Responders After Initiating Therapy for Recurrent Glioblastoma. ( Beppu, T; Kato, K; Ogasawara, K; Sasaki, M; Sasaki, T; Sato, Y; Terasaki, K; Tomabechi, M, 2016) |
"A total of nine patients with malignant glioma, postoperatively presenting with a Karnofsky performance score (KPS) below 70, were treated with standalone metronomic low-dose chemotherapy with temozolomide and celecoxib (cyclo-oxygenase-2 inhibitor)." | 7.81 | Dual Anti-angiogenic Chemotherapy with Temozolomide and Celecoxib in Selected Patients with Malignant Glioma Not Eligible for Standard Treatment. ( Brawanski, KR; Freyschlag, CF; Grams, AE; Kerschbaumer, J; Nowosielski, M; Petr, O; Pinggera, D; Schmidt, FA; Seiz, M; Thomé, C; Tuettenberg, J, 2015) |
"Our laboratory reported that Irinophore C™ (IrC™; a lipid-based nanoparticulate formulation of irinotecan) is effective against an orthotopic model of glioblastoma (GBM) and that treatment with IrC™ was associated with vascular normalization within the tumor." | 7.81 | Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma. ( Anantha, M; Backstrom, I; Bally, MB; Chu, F; Kalra, J; Masin, D; Strutt, D; Verreault, M; Walker, D; Waterhouse, D; Wehbe, M; Yapp, DT, 2015) |
"Present work mainly evaluated the inhibitory effects of lidamycin (LDM), an enediyne antibiotic, on angiogenesis or glioma-induced angiogenesis in vitro and in vivo, especially its synergistic anti-angiogenesis with temozolomide (TMZ)." | 7.80 | Synergistic inhibition of angiogenesis and glioma cell-induced angiogenesis by the combination of temozolomide and enediyne antibiotic lidamycin. ( Li, XQ; Li, Y; Liu, H; Ouyang, ZG; Shang, Y; Zhang, SH; Zhen, YS, 2014) |
"In the U87 intracerebral glioma model, within the first day of administration of cediranib, the intratumoral concentrations of TMZ in tumor ECF were slightly, but not statistically significantly, increased when compared to the treatment of TMZ alone with radiographic evidence of a normalized BBB." | 7.79 | Microdialysis measurement of intratumoral temozolomide concentration after cediranib, a pan-VEGF receptor tyrosine kinase inhibitor, in a U87 glioma model. ( Blakeley, JO; Brem, H; Grossman, R; Khan, U; Kim, E; Pathak, AP; Rudek, MA; Tyler, B; Zadnik, P, 2013) |
"Bortezomib induced caspase-3 activation and apoptotic cell death in stable glioma cell lines and in glioma stem-like cells (GSCs) derived from malignant tumor specimens Furthermore, TMZ-resistant glioma cell lines retained susceptibility to the proteasome inhibition." | 7.79 | Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis. ( Alexandru, D; Bigner, D; Bota, DA; Friedman, HS; Keir, ST; Vredenburgh, J, 2013) |
" Recently, in a phase II trial in Brazil for the treatment of temozolomide (TMZ)-resistant malignant gliomas, POH was well tolerated when administered intranasally." | 7.78 | Perillyl alcohol for the treatment of temozolomide-resistant gliomas. ( Chen, TC; Cho, HY; Goldkorn, A; Hofman, FM; Jhaveri, N; Lee, DJ; Leong, MN; Louie, SG; Petasis, NA; Schönthal, AH; Torres, S; Tseng, J; Wang, W; Xu, T, 2012) |
"Temozolomide (TM) has anti-tumor activity in patients with malignant glioma." | 7.76 | Temozolomide/PLGA microparticles plus vatalanib inhibits tumor growth and angiogenesis in an orthotopic glioma model. ( Liu, JM; Tang, GS; Wang, Y; Yue, ZJ; Zhang, H; Zhang, YH, 2010) |
"Temozolomide is considered the standard of care and drug of choice for the treatment of initially diagnosed malignant gliomas." | 7.75 | Glioma-associated endothelial cells are chemoresistant to temozolomide. ( Chen, TC; Golden, EB; Hofman, FM; Pen, L; Schönthal, AH; Sivakumar, W; Virrey, JJ; Wang, W, 2009) |
"The chemotherapeutic agent temozolomide (TMZ) and the anti-angiogenic agent thalidomide (THD) have both demonstrated anti-tumor activity in patients with recurrent malignant glioma." | 7.73 | Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model. ( Jeon, HJ; Kim, H; Kim, JH; Kim, JS; Kim, JT; Kim, MH; Kim, YJ; Lee, DS; Nam, DH; Park, SY; Shin, T; Son, MJ; Song, HS, 2006) |
" Metronomic dosing of cytotoxic chemotherapy has emerged as a promising option to achieve this objective." | 6.82 | Phase I study of low-dose metronomic temozolomide for recurrent malignant gliomas. ( Alsop, DC; Callahan, A; Giarusso, B; O'Loughlin, L; Timmons, J; Wong, ET, 2016) |
" Thus, our results show that polymeric nanocapsules are able to increase the intratumoral bioavailability of indomethacin and reduce the growth of implanted gliomas." | 5.35 | Indomethacin-loaded nanocapsules treatment reduces in vivo glioblastoma growth in a rat glioma model. ( Battastini, AM; Bernardi, A; Braganhol, E; Edelweiss, MI; Figueiró, F; Guterres, SS; Jäger, E; Pohlmann, AR, 2009) |
"Thirteen patients with recurrent glioblastoma were enrolled in RTOG 0625/ACRIN 6677, a prospective multicenter trial in which bevacizumab was used in combination with either temozolomide or irinotecan." | 5.17 | Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677. ( Barboriak, DP; Bokstein, F; Boxerman, JL; Gilbert, MR; McKinstry, RC; Ratai, EM; Safriel, Y; Snyder, BS; Sorensen, AG; Zhang, Z, 2013) |
"A phase II trial was initiated to analyze the activity of continuously administered pioglitazone and rofecoxib combined with low-dose chemotherapy (capecitabine or temozolomide) in patients with high-grade gliomas (glioblastoma or anaplastic glioma)." | 5.12 | Low-dose chemotherapy in combination with COX-2 inhibitors and PPAR-gamma agonists in recurrent high-grade gliomas - a phase II study. ( Baumgart, U; Bogdahn, U; Hau, P; Hirschmann, B; Kunz-Schughart, L; Muhleisen, H; Reichle, A; Ruemmele, P; Steinbrecher, A; Weimann, E, 2007) |
"In the last decade, phase III trials on novel compounds largely failed to introduce efficacious pharmacotherapies beyond temozolomide in glioblastoma." | 4.93 | Pharmacotherapies for the treatment of glioblastoma - current evidence and perspectives. ( Gramatzki, D; Roth, P; Seystahl, K; Weller, M, 2016) |
"Thirty rats with glioma were divided into control group, temozolomide (TMZ) group (TMZ 30 mg/kg once daily for 5 day), and TMZ plus Caffeine group (TMZ 30 mg/kg once daily for 5 day and caffeine 100 mg/kg once daily for 2 weeks)." | 4.12 | Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats. ( Chen, JC; Hwang, JH, 2022) |
" Therefore, we aimed to examine the Synergistic effects of Gefitinib (GFI) in combination with Temozolomide on VEGF and MMPs in glioma cell line (U87MG)." | 4.12 | Synergistic Effect of Gefitinib and Temozolomide on U87MG Glioblastoma Angiogenesis. ( Hossienpour, M; Karami, A; Kiani, A; Mohammadi Noori, E; Najafi, K; Rahpyma, M, 2022) |
" The aim of this study was to clarify whether PET with C-methyl-L-methionine (MET-PET) would supplement MRI assessing of response after initiating BEV in glioblastoma." | 3.83 | MRI and 11C-methyl-L-methionine PET Differentiate Bevacizumab True Responders After Initiating Therapy for Recurrent Glioblastoma. ( Beppu, T; Kato, K; Ogasawara, K; Sasaki, M; Sasaki, T; Sato, Y; Terasaki, K; Tomabechi, M, 2016) |
"Our laboratory reported that Irinophore C™ (IrC™; a lipid-based nanoparticulate formulation of irinotecan) is effective against an orthotopic model of glioblastoma (GBM) and that treatment with IrC™ was associated with vascular normalization within the tumor." | 3.81 | Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma. ( Anantha, M; Backstrom, I; Bally, MB; Chu, F; Kalra, J; Masin, D; Strutt, D; Verreault, M; Walker, D; Waterhouse, D; Wehbe, M; Yapp, DT, 2015) |
"A total of nine patients with malignant glioma, postoperatively presenting with a Karnofsky performance score (KPS) below 70, were treated with standalone metronomic low-dose chemotherapy with temozolomide and celecoxib (cyclo-oxygenase-2 inhibitor)." | 3.81 | Dual Anti-angiogenic Chemotherapy with Temozolomide and Celecoxib in Selected Patients with Malignant Glioma Not Eligible for Standard Treatment. ( Brawanski, KR; Freyschlag, CF; Grams, AE; Kerschbaumer, J; Nowosielski, M; Petr, O; Pinggera, D; Schmidt, FA; Seiz, M; Thomé, C; Tuettenberg, J, 2015) |
"Present work mainly evaluated the inhibitory effects of lidamycin (LDM), an enediyne antibiotic, on angiogenesis or glioma-induced angiogenesis in vitro and in vivo, especially its synergistic anti-angiogenesis with temozolomide (TMZ)." | 3.80 | Synergistic inhibition of angiogenesis and glioma cell-induced angiogenesis by the combination of temozolomide and enediyne antibiotic lidamycin. ( Li, XQ; Li, Y; Liu, H; Ouyang, ZG; Shang, Y; Zhang, SH; Zhen, YS, 2014) |
"Bortezomib induced caspase-3 activation and apoptotic cell death in stable glioma cell lines and in glioma stem-like cells (GSCs) derived from malignant tumor specimens Furthermore, TMZ-resistant glioma cell lines retained susceptibility to the proteasome inhibition." | 3.79 | Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis. ( Alexandru, D; Bigner, D; Bota, DA; Friedman, HS; Keir, ST; Vredenburgh, J, 2013) |
"In the U87 intracerebral glioma model, within the first day of administration of cediranib, the intratumoral concentrations of TMZ in tumor ECF were slightly, but not statistically significantly, increased when compared to the treatment of TMZ alone with radiographic evidence of a normalized BBB." | 3.79 | Microdialysis measurement of intratumoral temozolomide concentration after cediranib, a pan-VEGF receptor tyrosine kinase inhibitor, in a U87 glioma model. ( Blakeley, JO; Brem, H; Grossman, R; Khan, U; Kim, E; Pathak, AP; Rudek, MA; Tyler, B; Zadnik, P, 2013) |
" Recently, in a phase II trial in Brazil for the treatment of temozolomide (TMZ)-resistant malignant gliomas, POH was well tolerated when administered intranasally." | 3.78 | Perillyl alcohol for the treatment of temozolomide-resistant gliomas. ( Chen, TC; Cho, HY; Goldkorn, A; Hofman, FM; Jhaveri, N; Lee, DJ; Leong, MN; Louie, SG; Petasis, NA; Schönthal, AH; Torres, S; Tseng, J; Wang, W; Xu, T, 2012) |
"Temozolomide (TM) has anti-tumor activity in patients with malignant glioma." | 3.76 | Temozolomide/PLGA microparticles plus vatalanib inhibits tumor growth and angiogenesis in an orthotopic glioma model. ( Liu, JM; Tang, GS; Wang, Y; Yue, ZJ; Zhang, H; Zhang, YH, 2010) |
"Temozolomide is considered the standard of care and drug of choice for the treatment of initially diagnosed malignant gliomas." | 3.75 | Glioma-associated endothelial cells are chemoresistant to temozolomide. ( Chen, TC; Golden, EB; Hofman, FM; Pen, L; Schönthal, AH; Sivakumar, W; Virrey, JJ; Wang, W, 2009) |
"In mice bearing SF188V+ human glioma xenografts, measurements of temozolomide pharmacokinetic properties and sunitinib pharmacodynamic activities were evaluated, the latter including determinants for vascular normalization, including CD31, collagen IV, and alpha-SMA." | 3.74 | Impact of angiogenesis inhibition by sunitinib on tumor distribution of temozolomide. ( Gallo, JM; Guo, P; Zhou, Q, 2008) |
"The chemotherapeutic agent temozolomide (TMZ) and the anti-angiogenic agent thalidomide (THD) have both demonstrated anti-tumor activity in patients with recurrent malignant glioma." | 3.73 | Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model. ( Jeon, HJ; Kim, H; Kim, JH; Kim, JS; Kim, JT; Kim, MH; Kim, YJ; Lee, DS; Nam, DH; Park, SY; Shin, T; Son, MJ; Song, HS, 2006) |
" Metronomic dosing of cytotoxic chemotherapy has emerged as a promising option to achieve this objective." | 2.82 | Phase I study of low-dose metronomic temozolomide for recurrent malignant gliomas. ( Alsop, DC; Callahan, A; Giarusso, B; O'Loughlin, L; Timmons, J; Wong, ET, 2016) |
"Glioblastomas are rich in blood vessels (i." | 2.58 | Anti-angiogenic therapy for high-grade glioma. ( Ameratunga, M; Grant, R; Khasraw, M; Pavlakis, N; Simes, J; Wheeler, H, 2018) |
"Aggressive pituitary adenomas, defined from a clinical perspective, have earlier and more frequent recurrences and can be resistant to conventional treatments." | 2.50 | Aggressive pituitary adenomas--diagnosis and emerging treatments. ( Cusimano, MD; Di Ieva, A; Kovacs, K; Rotondo, F; Syro, LV, 2014) |
"Primary brain tumors are hallmarked for their destructive activity on the microenvironment and vasculature." | 1.43 | A versatile ex vivo technique for assaying tumor angiogenesis and microglia in the brain. ( Buchfelder, M; Eyüpoglu, IY; Fan, Z; Ghoochani, A; Hock, S; Savaskan, NE; Sehm, T; Yakubov, E, 2016) |
"Glioma is one of the most aggressive and lethal human brain tumors." | 1.40 | MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras. ( Chen, Q; Jiang, BH; Jiang, C; Jiang, T; Kang, C; Li, C; Li, H; Liu, LZ; Liu, N; Liu, X; Qian, X; Shi, Z; Wang, L; Wang, X; You, Y, 2014) |
"To report the serial development of oral mucositis following infusion of bevacizumab in a young woman with a malignant brain tumor and history of cutaneous psoriasis." | 1.38 | Bevacizumab-induced oral mucositis in background of cutaneous plaque-type psoriasis. ( Cuellar, S; Popa, AM; Radhakrishnan, L; Valla, K; Villano, JL, 2012) |
" These combinations appear to be the most promising for in vivo pre-clinical studies, with a view to testing in melanoma patients as a continuous dosing strategy, due to the in vitro additive inhibitory effect on growth seen in both endothelial and cancer cells." | 1.36 | Sorafenib enhances the in vitro anti-endothelial effects of low dose (metronomic) chemotherapy. ( Cawkwell, L; Little, SJ; Maraveyas, A; Murray, A; Stanley, P, 2010) |
" Thus, our results show that polymeric nanocapsules are able to increase the intratumoral bioavailability of indomethacin and reduce the growth of implanted gliomas." | 1.35 | Indomethacin-loaded nanocapsules treatment reduces in vivo glioblastoma growth in a rat glioma model. ( Battastini, AM; Bernardi, A; Braganhol, E; Edelweiss, MI; Figueiró, F; Guterres, SS; Jäger, E; Pohlmann, AR, 2009) |
"Gliomatosis cerebri is a rare primary cerebral tumour entity characterized by diffuse infiltrative growth patterns representing a WHO grade III malignancy." | 1.35 | First experiences with low-dose anti-angiogenic treatment in gliomatosis cerebri with signs of angiogenic activity. ( Brockmann, MA; Hermes, P; Kohlhof, P; Neumaier-Probst, E; Schmieder, K; Seiz, M; Tuettenberg, J; Vajkoczy, P; VON Deimling, A, 2009) |
"Glioblastomas are highly aggressive primary brain tumors." | 1.35 | Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization. ( Claes, A; Heerschap, A; Jeuken, J; Leenders, WP; Maass, C; Wesseling, P, 2008) |
"Temozolomide is a proautophagic (type II programmed cell death) drug and can thus circumvent part of the glioblastoma resistance to apoptosis." | 1.35 | [The sodium pump could constitute a new target to combat glioblastomas]. ( Kiss, R; Lefranc, F; Mijatovic, T, 2008) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (7.02) | 18.2507 |
2000's | 14 (24.56) | 29.6817 |
2010's | 33 (57.89) | 24.3611 |
2020's | 6 (10.53) | 2.80 |
Authors | Studies |
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Urbantat, RM | 1 |
Jelgersma, C | 1 |
Brandenburg, S | 1 |
Nieminen-Kelhä, M | 1 |
Kremenetskaia, I | 1 |
Zollfrank, J | 1 |
Mueller, S | 1 |
Rubarth, K | 1 |
Koch, A | 1 |
Vajkoczy, P | 3 |
Acker, G | 1 |
Pai, FC | 1 |
Huang, HW | 1 |
Tsai, YL | 1 |
Tsai, WC | 1 |
Cheng, YC | 1 |
Chang, HH | 1 |
Chen, Y | 4 |
Fu, X | 1 |
Xiong, B | 1 |
Zhao, M | 1 |
Wan, W | 1 |
Zhang, S | 3 |
Wu, X | 2 |
Xu, J | 1 |
Bittencourt, LFF | 1 |
Negreiros-Lima, GL | 1 |
Sousa, LP | 1 |
Silva, AG | 1 |
Souza, IBS | 1 |
Ribeiro, RIMA | 1 |
Dutra, MF | 1 |
Silva, RF | 1 |
Dias, ACF | 1 |
Soriani, FM | 1 |
Martins, WK | 1 |
Barcelos, LS | 1 |
Çetin, A | 1 |
Biltekin, B | 1 |
Nguépy Keubo, FR | 1 |
Mboua, PC | 1 |
Djifack Tadongfack, T | 1 |
Fokouong Tchoffo, E | 1 |
Tasson Tatang, C | 1 |
Ide Zeuna, J | 1 |
Noupoue, EM | 1 |
Tsoplifack, CB | 1 |
Folefack, GO | 1 |
Kettani, M | 1 |
Bandelier, P | 1 |
Huo, J | 1 |
Li, H | 5 |
Yu, D | 1 |
Arulsamy, N | 1 |
AlAbbad, S | 1 |
Sardot, T | 1 |
Lekashvili, O | 1 |
Decato, D | 1 |
Lelj, F | 1 |
Alexander Ross, JB | 1 |
Rosenberg, E | 1 |
Nazir, H | 1 |
Muthuswamy, N | 1 |
Louis, C | 1 |
Jose, S | 1 |
Prakash, J | 1 |
Buan, MEM | 1 |
Flox, C | 1 |
Chavan, S | 1 |
Shi, X | 1 |
Kauranen, P | 1 |
Kallio, T | 1 |
Maia, G | 1 |
Tammeveski, K | 1 |
Lymperopoulos, N | 1 |
Carcadea, E | 1 |
Veziroglu, E | 1 |
Iranzo, A | 1 |
M Kannan, A | 1 |
Arunamata, A | 1 |
Tacy, TA | 1 |
Kache, S | 1 |
Mainwaring, RD | 1 |
Ma, M | 1 |
Maeda, K | 1 |
Punn, R | 1 |
Noguchi, S | 1 |
Hahn, S | 3 |
Iwasa, Y | 3 |
Ling, J | 2 |
Voccio, JP | 2 |
Kim, Y | 3 |
Song, J | 3 |
Bascuñán, J | 2 |
Chu, Y | 1 |
Tomita, M | 1 |
Cazorla, M | 1 |
Herrera, E | 1 |
Palomeque, E | 1 |
Saud, N | 1 |
Hoplock, LB | 1 |
Lobchuk, MM | 1 |
Lemoine, J | 1 |
Li, X | 10 |
Henson, MA | 1 |
Unsihuay, D | 1 |
Qiu, J | 1 |
Swaroop, S | 1 |
Nagornov, KO | 1 |
Kozhinov, AN | 1 |
Tsybin, YO | 1 |
Kuang, S | 1 |
Laskin, J | 1 |
Zin, NNINM | 1 |
Mohamad, MN | 1 |
Roslan, K | 1 |
Abdul Wafi, S | 1 |
Abdul Moin, NI | 1 |
Alias, A | 1 |
Zakaria, Y | 1 |
Abu-Bakar, N | 1 |
Naveed, A | 1 |
Jilani, K | 1 |
Siddique, AB | 1 |
Akbar, M | 1 |
Riaz, M | 1 |
Mushtaq, Z | 1 |
Sikandar, M | 1 |
Ilyas, S | 1 |
Bibi, I | 1 |
Asghar, A | 1 |
Rasool, G | 1 |
Irfan, M | 1 |
Li, XY | 1 |
Zhao, S | 1 |
Fan, XH | 1 |
Chen, KP | 1 |
Hua, W | 1 |
Liu, ZM | 1 |
Xue, XD | 1 |
Zhou, B | 1 |
Xing, YL | 1 |
Chen, MA | 1 |
Sun, Y | 1 |
Neradilek, MB | 1 |
Wu, XT | 1 |
Zhang, D | 3 |
Huang, W | 1 |
Cui, Y | 1 |
Yang, QQ | 1 |
Li, HW | 1 |
Zhao, XQ | 1 |
Hossein Rashidi, B | 1 |
Tarafdari, A | 1 |
Ghazimirsaeed, ST | 1 |
Shahrokh Tehraninezhad, E | 1 |
Keikha, F | 1 |
Eslami, B | 1 |
Ghazimirsaeed, SM | 1 |
Jafarabadi, M | 1 |
Silvani, Y | 1 |
Lovita, AND | 1 |
Maharani, A | 1 |
Wiyasa, IWA | 1 |
Sujuti, H | 1 |
Ratnawati, R | 1 |
Raras, TYM | 1 |
Lemin, AS | 1 |
Rahman, MM | 1 |
Pangarah, CA | 1 |
Kiyu, A | 1 |
Zeng, C | 2 |
Du, H | 1 |
Lin, D | 1 |
Jalan, D | 1 |
Rubagumya, F | 1 |
Hopman, WM | 1 |
Vanderpuye, V | 1 |
Lopes, G | 1 |
Seruga, B | 1 |
Booth, CM | 1 |
Berry, S | 1 |
Hammad, N | 1 |
Sajo, EA | 1 |
Okunade, KS | 1 |
Olorunfemi, G | 1 |
Rabiu, KA | 1 |
Anorlu, RI | 1 |
Xu, C | 2 |
Xiang, Y | 1 |
Xu, X | 1 |
Zhou, L | 2 |
Dong, X | 1 |
Tang, S | 1 |
Gao, XC | 1 |
Wei, CH | 1 |
Zhang, RG | 1 |
Cai, Q | 1 |
He, Y | 1 |
Tong, F | 1 |
Dong, JH | 1 |
Wu, G | 1 |
Dong, XR | 1 |
Tang, X | 1 |
Tao, F | 1 |
Xiang, W | 1 |
Zhao, Y | 2 |
Jin, L | 1 |
Tao, H | 1 |
Lei, Y | 1 |
Gan, H | 1 |
Huang, Y | 2 |
Chen, L | 3 |
Shan, A | 1 |
Zhao, H | 2 |
Wu, M | 2 |
Ma, Q | 1 |
Wang, J | 4 |
Zhang, E | 1 |
Zhang, J | 3 |
Li, Y | 6 |
Xue, F | 1 |
Deng, L | 1 |
Liu, L | 2 |
Yan, Z | 2 |
Wang, Y | 3 |
Meng, J | 1 |
Chen, G | 2 |
Anastassiadou, M | 1 |
Bernasconi, G | 1 |
Brancato, A | 1 |
Carrasco Cabrera, L | 1 |
Greco, L | 1 |
Jarrah, S | 1 |
Kazocina, A | 1 |
Leuschner, R | 1 |
Magrans, JO | 1 |
Miron, I | 1 |
Nave, S | 1 |
Pedersen, R | 1 |
Reich, H | 1 |
Rojas, A | 1 |
Sacchi, A | 1 |
Santos, M | 1 |
Theobald, A | 1 |
Vagenende, B | 1 |
Verani, A | 1 |
Du, L | 1 |
Liu, X | 2 |
Ren, Y | 1 |
Li, J | 8 |
Li, P | 1 |
Jiao, Q | 1 |
Meng, P | 1 |
Wang, F | 2 |
Wang, YS | 1 |
Wang, C | 3 |
Zhou, X | 2 |
Wang, W | 3 |
Wang, S | 2 |
Hou, J | 1 |
Zhang, A | 1 |
Lv, B | 1 |
Gao, C | 1 |
Pang, D | 1 |
Lu, K | 1 |
Ahmad, NH | 1 |
Wang, L | 2 |
Zhu, J | 2 |
Zhang, L | 3 |
Zhuang, T | 1 |
Tu, J | 1 |
Zhao, Z | 1 |
Qu, Y | 1 |
Yao, H | 1 |
Wang, X | 6 |
Lee, DF | 1 |
Shen, J | 3 |
Wen, L | 1 |
Huang, G | 2 |
Xie, X | 1 |
Zhao, Q | 1 |
Hu, W | 1 |
Zhang, Y | 4 |
Lu, J | 2 |
Li, M | 1 |
Li, W | 2 |
Wu, W | 1 |
Du, F | 1 |
Ji, H | 1 |
Yang, X | 3 |
Xu, Z | 1 |
Wan, L | 1 |
Wen, Q | 1 |
Cho, CH | 1 |
Zou, C | 1 |
Xiao, Z | 1 |
Liao, J | 1 |
Su, X | 1 |
Bi, Z | 1 |
Su, Q | 1 |
Huang, H | 1 |
Wei, Y | 2 |
Gao, Y | 2 |
Na, KJ | 1 |
Choi, H | 1 |
Oh, HR | 1 |
Kim, YH | 1 |
Lee, SB | 1 |
Jung, YJ | 1 |
Koh, J | 1 |
Park, S | 1 |
Lee, HJ | 1 |
Jeon, YK | 1 |
Chung, DH | 1 |
Paeng, JC | 1 |
Park, IK | 1 |
Kang, CH | 1 |
Cheon, GJ | 1 |
Kang, KW | 1 |
Lee, DS | 3 |
Kim, YT | 1 |
Pajuelo-Lozano, N | 1 |
Alcalá, S | 1 |
Sainz, B | 1 |
Perona, R | 1 |
Sanchez-Perez, I | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Solitary Fibrous Tumor: Phase II Study on Trabectedin Versus Adriamycin Plus Dacarbazine in Advanced Patients[NCT03023124] | Phase 2 | 50 participants (Anticipated) | Interventional | 2018-03-04 | Recruiting | ||
Evaluation of Topical Application of 5% Imiquimod, 0.05% Imiquimod and 0.05% Nanoencapsulated Imiquimod Gel in the Treatment of Actinic Cheilitis: a Randomized Controlled Trial[NCT04219358] | Phase 1 | 49 participants (Actual) | Interventional | 2019-03-23 | Terminated (stopped due to Study terminated because of COVID19 pandemics.) | ||
A Phase II Trial of Concurrent Sunitinib, Temozolomide and Radiation Therapy Followed by Adjuvant Temozolomide for Newly Diagnosed Glioblastoma Patients With an Unmethylated MGMT Gene Promoter[NCT02928575] | Phase 2 | 45 participants (Anticipated) | Interventional | 2012-08-31 | Recruiting | ||
Metabolomic Profiling of Erector Spinae Plane Block for Breast Cancer Surgery[NCT04689945] | 91 participants (Actual) | Observational | 2021-02-01 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
8 reviews available for temozolomide and Angiogenesis, Pathologic
Article | Year |
---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Anti-angiogenic therapy for high-grade glioma.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brai | 2018 |
Aggressive pituitary adenomas--diagnosis and emerging treatments.
Topics: Adenoma; Biomarkers, Tumor; Dacarbazine; Humans; Ki-67 Antigen; Neoplasm Invasiveness; Neovasculariz | 2014 |
Antiangiogenic therapy for high-grade glioma.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brai | 2014 |
Pharmacotherapies for the treatment of glioblastoma - current evidence and perspectives.
Topics: Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblastoma; Humans; Neovascu | 2016 |
[Association of radiotherapy and chemotherapy-targeted therapies in glioblastomas].
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A | 2009 |
New anticancer agents.
Topics: Animals; Antineoplastic Agents; Dacarbazine; Humans; Lactones; Macrolides; Neovascularization, Patho | 1997 |
New chemotherapy options for the treatment of malignant gliomas.
Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Camptothecin; Clinical Trials as Topic; Dacarbazine; | 1999 |
4 trials available for temozolomide and Angiogenesis, Pathologic
Article | Year |
---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Be | 2013 |
Phase I study of low-dose metronomic temozolomide for recurrent malignant gliomas.
Topics: Administration, Metronomic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Bioma | 2016 |
Low-dose chemotherapy in combination with COX-2 inhibitors and PPAR-gamma agonists in recurrent high-grade gliomas - a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Capecitabin | 2007 |
46 other studies available for temozolomide and Angiogenesis, Pathologic
Article | Year |
---|---|
Tumor-Associated Microglia/Macrophages as a Predictor for Survival in Glioblastoma and Temozolomide-Induced Changes in CXCR2 Signaling with New Resistance Overcoming Strategy by Combination Therapy.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined | 2021 |
Inhibition of FABP6 Reduces Tumor Cell Invasion and Angiogenesis through the Decrease in MMP-2 and VEGF in Human Glioblastoma Cells.
Topics: Animals; Cell Line, Tumor; Cell Movement; Clone Cells; Disease Progression; Extracellular Matrix; Fa | 2021 |
Quinacrine is active in preclinical models of glioblastoma through suppressing angiogenesis, inducing oxidative stress and activating AMPK.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Glioblastom | 2022 |
G3BP1 knockdown sensitizes U87 glioblastoma cell line to Bortezomib by inhibiting stress granules assembly and potentializing apoptosis.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Bortezomib; Cell Proliferation; | 2019 |
Combining Ellagic Acid with Temozolomide Mediates the Cadherin Switch and Angiogenesis in a Glioblastoma Model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cadherins; Cell Line, Tumor; Disease Models | 2019 |
Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats.
Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Caffeine; Cell Line, Tumor; Endoplasmic Reticulum St | 2022 |
Synergistic Effect of Gefitinib and Temozolomide on U87MG Glioblastoma Angiogenesis.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Dru | 2022 |
Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Blood Vessels; Brain Neoplasms; | 2017 |
Aberrant glioblastoma neovascularization patterns and their correlation with DCE-MRI-derived parameters following temozolomide and bevacizumab treatment.
Topics: Animals; Bevacizumab; Cell Line, Tumor; Cell Transformation, Neoplastic; Contrast Media; Drug Resist | 2017 |
Tumour cell dormancy as a contributor to the reduced survival of GBM patients who received standard therapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Cell Movement; Cell Proliferation; Combi | 2018 |
Genetic variants related to angiogenesis and apoptosis in patients with glioma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neop | 2018 |
Podoplanin expression is a prognostic biomarker but may be dispensable for the malignancy of glioblastoma.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cel | 2019 |
Microdialysis measurement of intratumoral temozolomide concentration after cediranib, a pan-VEGF receptor tyrosine kinase inhibitor, in a U87 glioma model.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineop | 2013 |
Dacarbazine in solitary fibrous tumor: a case series analysis and preclinical evidence vis-a-vis temozolomide and antiangiogenics.
Topics: Adult; Aged; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protoc | 2013 |
Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosi | 2013 |
Synergistic inhibition of angiogenesis and glioma cell-induced angiogenesis by the combination of temozolomide and enediyne antibiotic lidamycin.
Topics: Aminoglycosides; Angiogenesis Inhibitors; Animals; Anti-Bacterial Agents; Apoptosis; Brain; Brain Ne | 2014 |
MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras.
Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Genes | 2014 |
Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma.
Topics: Angiogenesis Inhibitors; Animals; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cel | 2015 |
Recurrence of glioblastoma after radio-chemotherapy is associated with an angiogenic switch to the CXCL12-CXCR4 pathway.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Benzylamines; Brain Neoplasms; Chemokine | 2015 |
Dual Anti-angiogenic Chemotherapy with Temozolomide and Celecoxib in Selected Patients with Malignant Glioma Not Eligible for Standard Treatment.
Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Che | 2015 |
Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemoth | 2015 |
A versatile ex vivo technique for assaying tumor angiogenesis and microglia in the brain.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D | 2016 |
c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma.
Topics: Animals; Cell Hypoxia; Cell Movement; Cell Proliferation; Dacarbazine; Drug Resistance, Neoplasm; En | 2016 |
MRI and 11C-methyl-L-methionine PET Differentiate Bevacizumab True Responders After Initiating Therapy for Recurrent Glioblastoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazi | 2016 |
Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineo | 2008 |
Indomethacin-loaded nanocapsules treatment reduces in vivo glioblastoma growth in a rat glioma model.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Body Weight; Cell Division; Cell | 2009 |
Glioma-associated endothelial cells are chemoresistant to temozolomide.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Movement; Cell Prolife | 2009 |
First experiences with low-dose anti-angiogenic treatment in gliomatosis cerebri with signs of angiogenic activity.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Cell Proliferation; Cyclooxy | 2009 |
MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; | 2010 |
Sorafenib enhances the in vitro anti-endothelial effects of low dose (metronomic) chemotherapy.
Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Cell Lin | 2010 |
Temozolomide/PLGA microparticles plus vatalanib inhibits tumor growth and angiogenesis in an orthotopic glioma model.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoc | 2010 |
Taming glioblastoma by targeting angiogenesis: 3 years later.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A | 2011 |
Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme.
Topics: Blotting, Western; Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Primers; Flow Cytometry; F | 2011 |
Perillyl alcohol for the treatment of temozolomide-resistant gliomas.
Topics: Administration, Intranasal; Animals; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferati | 2012 |
Prognostic importance of markers for inflammation, angiogenesis and apoptosis in high grade glial tumors during temozolomide and radiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Dac | 2012 |
Bevacizumab-induced oral mucositis in background of cutaneous plaque-type psoriasis.
Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating | 2012 |
Augmenting chemosensitivity of malignant melanoma tumors via proteasome inhibition: implication for bortezomib (VELCADE, PS-341) as a therapeutic agent for malignant melanoma.
Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy | 2004 |
Continuous low-dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiforme.
Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemother | 2005 |
Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel | 2006 |
Metronomic treatment of temozolomide inhibits tumor cell growth through reduction of angiogenesis and augmentation of apoptosis in orthotopic models of gliomas.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Dacarbazine; Disease Models | 2006 |
Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blood-B | 2008 |
Impact of angiogenesis inhibition by sunitinib on tumor distribution of temozolomide.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Collagen; Co | 2008 |
[The sodium pump could constitute a new target to combat glioblastomas].
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; | 2008 |
Knocking down galectin 1 in human hs683 glioblastoma cells impairs both angiogenesis and endoplasmic reticulum stress responses.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Down-Reg | 2008 |
Uptake of temozolomide in a rat glioma model in the presence and absence of the angiogenesis inhibitor TNP-470.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cyclohexan | 1996 |
Modulation of angiogenesis by human glioma xenograft models that differentially express vascular endothelial growth factor.
Topics: Animals; Antineoplastic Agents, Alkylating; Capillaries; Carmustine; Cell Hypoxia; Dacarbazine; DNA, | 1998 |