temozolomide has been researched along with Anemia in 8 studies
Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lomeguatrib, an O(6)-methylguanine-DNA methyltransferase inactivator, was evaluated in an extended dosing regimen with temozolomide, designed according to pharmacodynamic data from previous studies." | 6.74 | A phase I study of extended dosing with lomeguatrib with temozolomide in patients with advanced melanoma. ( Abdi, E; Beith, J; Corrie, PG; Kefford, RF; Kotasek, D; Margison, GP; Middleton, MR; Mortimer, P; Palmer, C; Ranson, M; Thomas, NP; Watson, AJ, 2009) |
| "Ratio of log-transformed means (intravenous:oral) of area under the concentration-time curve and maximum concentration of drug after dosing for temozolomide and 5-(3-methyltriazen-1-yl)imidazole-4-carboxamide (MTIC) met exposure equivalence criteria (90% confidence interval = 0." | 2.75 | Evaluation of the exposure equivalence of oral versus intravenous temozolomide. ( Abutarif, MA; Cantillon, M; Cutler, D; Diez, BD; Kantesaria, B; Ottaviano, FH; Pallotta, MG; Schwarz, M; Statkevich, P; Xuan, F; Zhu, Y, 2010) |
| "Lomeguatrib, an O(6)-methylguanine-DNA methyltransferase inactivator, was evaluated in an extended dosing regimen with temozolomide, designed according to pharmacodynamic data from previous studies." | 2.74 | A phase I study of extended dosing with lomeguatrib with temozolomide in patients with advanced melanoma. ( Abdi, E; Beith, J; Corrie, PG; Kefford, RF; Kotasek, D; Margison, GP; Middleton, MR; Mortimer, P; Palmer, C; Ranson, M; Thomas, NP; Watson, AJ, 2009) |
| "To evaluate the efficacy of temozolomide (TMZ) combined with cisplatin (CDDP) in terms of response rate, time to progression (TTP) and overall survival (OS), as well as the tolerability of the regimen in patients with brain metastases from solid tumors." | 2.71 | Temozolomide (TMZ) combined with cisplatin (CDDP) in patients with brain metastases from solid tumors: a Hellenic Cooperative Oncology Group (HeCOG) Phase II study. ( Aravantinos, G; Bafaloukos, D; Bamias, A; Carina, M; Christodoulou, C; Klouvas, G; Linardou, H; Skarlos, D, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calegari, MA | 1 |
| Inno, A | 1 |
| Monterisi, S | 1 |
| Orlandi, A | 1 |
| Santini, D | 1 |
| Basso, M | 1 |
| Cassano, A | 1 |
| Martini, M | 1 |
| Cenci, T | 1 |
| de Pascalis, I | 1 |
| Camarda, F | 1 |
| Barbaro, B | 1 |
| Larocca, LM | 1 |
| Gori, S | 1 |
| Tonini, G | 1 |
| Barone, C | 1 |
| Kesavan, M | 1 |
| Claringbold, PG | 1 |
| Turner, JH | 1 |
| Kefford, RF | 1 |
| Thomas, NP | 1 |
| Corrie, PG | 1 |
| Palmer, C | 1 |
| Abdi, E | 1 |
| Kotasek, D | 1 |
| Beith, J | 1 |
| Ranson, M | 1 |
| Mortimer, P | 1 |
| Watson, AJ | 1 |
| Margison, GP | 1 |
| Middleton, MR | 1 |
| Diez, BD | 1 |
| Statkevich, P | 1 |
| Zhu, Y | 1 |
| Abutarif, MA | 1 |
| Xuan, F | 1 |
| Kantesaria, B | 1 |
| Cutler, D | 1 |
| Cantillon, M | 1 |
| Schwarz, M | 1 |
| Pallotta, MG | 1 |
| Ottaviano, FH | 1 |
| Seiter, K | 1 |
| Liu, D | 1 |
| Siddiqui, AD | 1 |
| Lerner, R | 1 |
| Nelson, J | 1 |
| Ahmed, T | 1 |
| Christodoulou, C | 1 |
| Bafaloukos, D | 1 |
| Linardou, H | 1 |
| Aravantinos, G | 1 |
| Bamias, A | 1 |
| Carina, M | 1 |
| Klouvas, G | 1 |
| Skarlos, D | 1 |
| Brandes, AA | 1 |
| Tosoni, A | 1 |
| Cavallo, G | 1 |
| Bertorelle, R | 1 |
| Gioia, V | 1 |
| Franceschi, E | 1 |
| Biscuola, M | 1 |
| Blatt, V | 1 |
| Crinò, L | 1 |
| Ermani, M | 1 |
| Gerber, DE | 1 |
| Grossman, SA | 1 |
| Zeltzman, M | 1 |
| Parisi, MA | 1 |
| Kleinberg, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| NIVOLUMAB Plus IPILIMUMAB and TEMOZOLOMIDE in Combination in Microsatellite Stable (MSS), MGMT Silenced Metastatic Colorectal Cancer (mCRC): the MAYA Study[NCT03832621] | Phase 2 | 135 participants (Actual) | Interventional | 2019-03-25 | Completed | ||
| Multicenter Phase II Study of Preoperative Chemoradiotherapy With CApecitabine Plus Temozolomide in Patients With MGMT Silenced and Microsatellite Stable Locally Advanced RecTal Cancer: the CATARTIC Trial[NCT05136326] | Phase 2 | 21 participants (Anticipated) | Interventional | 2021-12-01 | Recruiting | ||
| Phase 1b Trial of 5-fluorouracil, Leucovorin, Irinotecan in Combination With Temozolomide (FLIRT) and Bevacizumab for the First-line Treatment of Patients With MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer.[NCT04689347] | Phase 1 | 18 participants (Anticipated) | Interventional | 2021-01-01 | Recruiting | ||
| Temozolomide and Irinotecan Consolidation in Patients With MGMT Silenced, Microsatellite Stable Colorectal Cancer With Persistence of Minimal Residual Disease in Liquid Biopsy After Standard Adjuvant Chemotherapy: the ERASE-TMZ Study[NCT05031975] | Phase 2 | 35 participants (Anticipated) | Interventional | 2022-05-02 | Recruiting | ||
| Secondary Prophylaxis Use of Romiplostim for the Prevention of Thrombocytopenia Induced by Temozolomide in Newly Diagnosed Glioblastoma Patients[NCT02227576] | Phase 2 | 20 participants (Actual) | Interventional | 2014-07-10 | Terminated (stopped due to Study halted for efficacy following the results of the interim analysis provided for in the protocol on 20 patients.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 trials available for temozolomide and Anemia
| Article | Year |
|---|---|
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazin | 2017 |
Hematological toxicity of combined 177Lu-octreotate radiopeptide chemotherapy of gastroenteropancreatic neuroendocrine tumors in long-term follow-up.
Topics: Adult; Aged; Anemia; Antineoplastic Agents; Blood Platelets; Capecitabine; Dacarbazine; Deoxycytidin | 2014 |
A phase I study of extended dosing with lomeguatrib with temozolomide in patients with advanced melanoma.
Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Agents; Child; Dacarbazine; Dose-Response Relationsh | 2009 |
Evaluation of the exposure equivalence of oral versus intravenous temozolomide.
Topics: Administration, Oral; Adult; Anemia; Antineoplastic Agents, Alkylating; Area Under Curve; Central Ne | 2010 |
Evaluation of temozolomide in patients with myelodysplastic syndrome.
Topics: Aged; Anemia; Antineoplastic Agents, Alkylating; Cardiomyopathies; Dacarbazine; Drug Evaluation; Fem | 2004 |
Temozolomide (TMZ) combined with cisplatin (CDDP) in patients with brain metastases from solid tumors: a Hellenic Cooperative Oncology Group (HeCOG) Phase II study.
Topics: Adult; Aged; Alopecia; Anemia; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brea | 2005 |
Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from gruppo italiano cooperativo di neuro-oncologia (GICNO).
Topics: Adult; Aged; Anemia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Constipation; Dacarbazine; | 2006 |
1 other study available for temozolomide and Anemia
| Article | Year |
|---|---|
The impact of thrombocytopenia from temozolomide and radiation in newly diagnosed adults with high-grade gliomas.
Topics: Adult; Aged; Anemia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; | 2007 |