temozolomide has been researched along with Adenocarcinoma in 17 studies
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Temozolomide is effective in some patients with progressive pituitary adenoma or carcinoma." | 7.83 | Temozolomide therapy in patients with aggressive pituitary adenomas or carcinomas. ( Bogazzi, F; Cannavo, S; Ceccato, F; Curtò, L; De Marinis, L; Iacovazzo, D; Lombardi, G; Losa, M; Mantovani, G; Mazza, E; Minniti, G; Nizzoli, M; Reni, M; Scaroni, C, 2016) |
| "Pituitary carcinoma is extremely rare and difficult to diagnose early." | 5.40 | Pituitary atypical adenoma or carcinoma sensitive to temozolomide combined with radiation therapy: a case report of early identification and management. ( Jiang, S; Yin, S; Zhong, C; Zhou, P, 2014) |
| "Temozolomide is effective in some patients with progressive pituitary adenoma or carcinoma." | 3.83 | Temozolomide therapy in patients with aggressive pituitary adenomas or carcinomas. ( Bogazzi, F; Cannavo, S; Ceccato, F; Curtò, L; De Marinis, L; Iacovazzo, D; Lombardi, G; Losa, M; Mantovani, G; Mazza, E; Minniti, G; Nizzoli, M; Reni, M; Scaroni, C, 2016) |
| "The in vitro cytotoxicity of 8-carbamoyl-3-methylimidazo [5,1-d]-1,2,3,5-tetrazine-4(3H)-one (temozolomide) with concurrent X-irradiation was examined in a human glioblastoma cell line (U373MG) as a potential radio-chemotherapeutic treatment for malignant glioma." | 3.69 | In vitro evaluation of temozolomide combined with X-irradiation. ( Glaser, MG; Marcus, K; Newlands, ES; Porteous, JK; Wedge, SR, 1997) |
| "Temozolomide (SCH 52365) is an imidazotetrazine derivative which exhibits broad spectrum activity against murine tumors and is structurally related to dacarbazine (DTIC)." | 2.69 | A phase II study of temozolomide in advanced untreated pancreatic cancer. ( Feld, R; Hedley, D; Moore, MJ; Oza, A; Siu, LL, 1998) |
| "We developed a mouse model of Lynch syndrome (Lgr5-CreERT2;Msh2(flox/-) mice) and found that environmental factors can modify the number and mutability of the MMR-deficient stem cells." | 1.40 | Temozolomide increases the number of mismatch repair-deficient intestinal crypts and accelerates tumorigenesis in a mouse model of Lynch syndrome. ( Cantelli, E; De Vries, S; Dekker, M; Delzenne-Goette, E; Plug, M; Song, JY; Te Riele, H; Van Der Wal, A; Van Gerwen, B; Wojciechowicz, K, 2014) |
| "Metastases represent the most common brain tumors in adults." | 1.40 | Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain. ( Brem, H; Cima, M; Grossman, R; Hwang, L; Langer, R; Masi, B; Patta, Y; Scott, A; Spencer, K; Tyler, B; Upadhyay, UM; Wicks, R, 2014) |
| "Pituitary carcinoma is extremely rare and difficult to diagnose early." | 1.40 | Pituitary atypical adenoma or carcinoma sensitive to temozolomide combined with radiation therapy: a case report of early identification and management. ( Jiang, S; Yin, S; Zhong, C; Zhou, P, 2014) |
| "MGMT expression in brain metastases was significantly correlated with better survival." | 1.36 | O(6)-Methylguanine-DNA methyltransferase expression and prognostic value in brain metastases of lung cancers. ( Cheng, AL; Kuo, KT; Kuo, LT; Lee, WC; Lin, CH; Lin, YT; Lu, YS; Tasi, JC; Tseng, HM; Tseng, SH; Tu, YK; Wu, PF; Wu, RM; Yang, CH, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 10 (58.82) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Jammula, S | 1 |
| Katz-Summercorn, AC | 1 |
| Li, X | 1 |
| Linossi, C | 1 |
| Smyth, E | 1 |
| Killcoyne, S | 1 |
| Biasci, D | 1 |
| Subash, VV | 1 |
| Abbas, S | 1 |
| Blasko, A | 1 |
| Devonshire, G | 1 |
| Grantham, A | 1 |
| Wronowski, F | 1 |
| O'Donovan, M | 1 |
| Grehan, N | 1 |
| Eldridge, MD | 1 |
| Tavaré, S | 1 |
| Fitzgerald, RC | 1 |
| Liu, Y | 1 |
| Wojciechowicz, K | 1 |
| Cantelli, E | 1 |
| Van Gerwen, B | 1 |
| Plug, M | 1 |
| Van Der Wal, A | 1 |
| Delzenne-Goette, E | 1 |
| Song, JY | 1 |
| De Vries, S | 1 |
| Dekker, M | 1 |
| Te Riele, H | 1 |
| Upadhyay, UM | 1 |
| Tyler, B | 1 |
| Patta, Y | 1 |
| Wicks, R | 1 |
| Spencer, K | 1 |
| Scott, A | 1 |
| Masi, B | 1 |
| Hwang, L | 1 |
| Grossman, R | 1 |
| Cima, M | 1 |
| Brem, H | 1 |
| Langer, R | 1 |
| Zhong, C | 1 |
| Yin, S | 1 |
| Zhou, P | 1 |
| Jiang, S | 1 |
| Losa, M | 1 |
| Bogazzi, F | 1 |
| Cannavo, S | 1 |
| Ceccato, F | 1 |
| Curtò, L | 1 |
| De Marinis, L | 1 |
| Iacovazzo, D | 1 |
| Lombardi, G | 1 |
| Mantovani, G | 1 |
| Mazza, E | 1 |
| Minniti, G | 1 |
| Nizzoli, M | 1 |
| Reni, M | 1 |
| Scaroni, C | 1 |
| Zhang, L | 1 |
| Zeng, J | 1 |
| Zeng, Z | 1 |
| Wang, F | 1 |
| Wang, D | 1 |
| Chen, C | 1 |
| Li, C | 1 |
| An, X | 1 |
| Xu, R | 1 |
| Huang, P | 1 |
| Ba, Y | 1 |
| Li, Y | 1 |
| Deng, X | 1 |
| Zheng, Z | 1 |
| Lin, B | 1 |
| Su, H | 1 |
| Chen, H | 1 |
| Fei, S | 1 |
| Fei, Z | 1 |
| Zhao, L | 1 |
| Jin, X | 1 |
| Xie, CY | 1 |
| Wu, PF | 1 |
| Kuo, KT | 1 |
| Kuo, LT | 1 |
| Lin, YT | 1 |
| Lee, WC | 1 |
| Lu, YS | 1 |
| Yang, CH | 1 |
| Wu, RM | 1 |
| Tu, YK | 1 |
| Tasi, JC | 1 |
| Tseng, HM | 1 |
| Tseng, SH | 1 |
| Cheng, AL | 1 |
| Lin, CH | 1 |
| Shacham-Shmueli, E | 1 |
| Beny, A | 1 |
| Geva, R | 1 |
| Blachar, A | 1 |
| Figer, A | 1 |
| Aderka, D | 1 |
| Leng, S | 1 |
| Bernauer, AM | 1 |
| Hong, C | 1 |
| Do, KC | 1 |
| Yingling, CM | 1 |
| Flores, KG | 1 |
| Tessema, M | 1 |
| Tellez, CS | 1 |
| Willink, RP | 1 |
| Burki, EA | 1 |
| Picchi, MA | 1 |
| Stidley, CA | 1 |
| Prados, MD | 1 |
| Costello, JF | 1 |
| Gilliland, FD | 1 |
| Crowell, RE | 1 |
| Belinsky, SA | 1 |
| Kokkinakis, DM | 1 |
| Liu, X | 1 |
| Neuner, RD | 1 |
| Kato, Y | 1 |
| Okollie, B | 1 |
| Artemov, D | 1 |
| Wedge, SR | 1 |
| Porteous, JK | 1 |
| Glaser, MG | 1 |
| Marcus, K | 1 |
| Newlands, ES | 1 |
| Moore, MJ | 1 |
| Feld, R | 1 |
| Hedley, D | 1 |
| Oza, A | 1 |
| Siu, LL | 1 |
| Deans, B | 1 |
| Tisdale, MJ | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study Investigating Neoadjuvant Temozolomide-based Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas[NCT00881595] | Phase 2 | 0 participants (Actual) | Interventional | 2009-02-28 | Withdrawn (stopped due to No patients accrued since study opened) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for temozolomide and Adenocarcinoma
| Article | Year |
|---|---|
Leptomeningeal carcinomatosis from gastric cancer successfully treated by the intrathecal methotrexate plus temozolomide and simultaneous radiotherapy: Case report and literatures review.
Topics: Abdominal Pain; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Chemoradioth | 2017 |
1 trial available for temozolomide and Adenocarcinoma
| Article | Year |
|---|---|
A phase II study of temozolomide in advanced untreated pancreatic cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Alkylating; Dacarbazine; Humans; Middle Aged; Pancreati | 1998 |
15 other studies available for temozolomide and Adenocarcinoma
| Article | Year |
|---|---|
Identification of Subtypes of Barrett's Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Barrett Esophagus; Cyclin E; Disease Progression; DNA M | 2020 |
Temozolomide increases the number of mismatch repair-deficient intestinal crypts and accelerates tumorigenesis in a mouse model of Lynch syndrome.
Topics: Adenocarcinoma; Adenoma; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Ne | 2014 |
Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Capsules; | 2014 |
Pituitary atypical adenoma or carcinoma sensitive to temozolomide combined with radiation therapy: a case report of early identification and management.
Topics: Adenocarcinoma; Adenoma; Adult; Antineoplastic Agents, Alkylating; Dacarbazine; Female; Humans; Pitu | 2014 |
Temozolomide therapy in patients with aggressive pituitary adenomas or carcinomas.
Topics: Adenocarcinoma; Adenoma; Adult; Aged; Antineoplastic Agents, Alkylating; Dacarbazine; Female; Follow | 2016 |
MGMT in colorectal cancer: a promising component of personalized treatment.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Colorectal | 2016 |
The efficacy and roles of combining temozolomide with whole brain radiotherapy in protection neurocognitive function and improvement quality of life of non-small-cell lung cancer patients with brain metastases.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; | 2017 |
O(6)-Methylguanine-DNA methyltransferase expression and prognostic value in brain metastases of lung cancers.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; | 2010 |
Response to temozolomide in patients with metastatic colorectal cancer with loss of MGMT expression: a new approach in the era of personalized medicine?
Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Alkylating; Biopsy; Colectomy; Colorectal Neoplasms; Da | 2011 |
The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Aged; Antineoplastic Agents, Alkylating; beta-Galacto | 2011 |
Modulation of cell cycle and gene expression in pancreatic tumor cell lines by methionine deprivation (methionine stress): implications to the therapy of pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Blotting, Wester | 2005 |
Noninvasive 1H/13C magnetic resonance spectroscopic imaging of the intratumoral distribution of temozolomide.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Alkylating; Breast Neoplasms; Carbon Isotopes; Contr | 2006 |
In vitro evaluation of temozolomide combined with X-irradiation.
Topics: Adenocarcinoma; Antineoplastic Agents, Alkylating; Brain Neoplasms; Colonic Neoplasms; Combined Moda | 1997 |
Antitumour imidazotetrazines XXVIII 3-methyladenine DNA glycosylase activity in cell lines sensitive and resistant to temozolomide.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Burkitt Lymphoma; Cell Line; Cell Survival; Chromato | 1992 |
Antitumor imidazotetrazines--XV. Role of guanine O6 alkylation in the mechanism of cytotoxicity of imidazotetrazinones.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Chlorambucil; Colonic Neoplasms; Dacarbaz | 1987 |