temozolomide has been researched along with Abnormalities, Autosome in 6 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of oligodendroglioma that had consistent histopathological features as well as a distinct change in 1p/19q status in the second recurrence, after temozolomide chemotherapy and radiotherapy." | 4.12 | Recurrent oligodendroglioma with changed 1p/19q status. ( Barresi, V; Calicchia, M; Ghimenton, C; Mafficini, A; Musumeci, A; Piredda, ML; Scarpa, A, 2022) |
| "Three human colon cancer cell lines were used, SW480 cells, which are wild-type for mismatch repair genes and have mutated p53, HCT116 cells, which are mutant in hMLH1 and wild-type for p53, and HCT15 cells, which are mutant in hMSH6 and mutant in p53 as well." | 1.31 | Base excision repair as a therapeutic target in colon cancer. ( Gerson, SL; Liu, L; Nakatsuru, Y, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Barresi, V | 1 |
| Mafficini, A | 1 |
| Calicchia, M | 1 |
| Piredda, ML | 1 |
| Musumeci, A | 1 |
| Ghimenton, C | 1 |
| Scarpa, A | 1 |
| Garnier, L | 1 |
| Vidal, C | 1 |
| Chinot, O | 1 |
| Cohen-Jonathan Moyal, E | 1 |
| Djelad, A | 1 |
| Bronnimann, C | 1 |
| Bekaert, L | 1 |
| Taillandier, L | 2 |
| Frenel, JS | 1 |
| Langlois, O | 1 |
| Colin, P | 1 |
| Menei, P | 1 |
| Dhermain, F | 1 |
| Carpentier, C | 1 |
| Gerazime, A | 1 |
| Curtit, E | 1 |
| Figarella-Branger, D | 1 |
| Dehais, C | 1 |
| Ducray, F | 1 |
| Roos, WP | 1 |
| Nikolova, T | 1 |
| Quiros, S | 1 |
| Naumann, SC | 1 |
| Kiedron, O | 1 |
| Zdzienicka, MZ | 1 |
| Kaina, B | 1 |
| Liu, L | 1 |
| Nakatsuru, Y | 1 |
| Gerson, SL | 1 |
| Leuraud, P | 1 |
| Medioni, J | 1 |
| Aguirre-Cruz, L | 1 |
| Crinière, E | 1 |
| Marie, Y | 1 |
| Kujas, M | 1 |
| Golmard, JL | 1 |
| Duprez, A | 1 |
| Delattre, JY | 1 |
| Sanson, M | 1 |
| Poupon, MF | 1 |
| Tentori, L | 1 |
| Portarena, I | 1 |
| Vernole, P | 1 |
| De Fabritiis, P | 1 |
| Madaio, R | 1 |
| Balduzzi, A | 1 |
| Roy, R | 1 |
| Bonmassar, E | 1 |
| Graziani, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I/II Trial of TRC102 (Methoxyamine HCl) in Combination With Temozolomide in Patients With Relapsed Solid Tumors and Lymphomas[NCT01851369] | Phase 1/Phase 2 | 93 participants (Actual) | Interventional | 2013-07-12 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for temozolomide and Abnormalities, Autosome
| Article | Year |
|---|---|
Recurrent oligodendroglioma with changed 1p/19q status.
Topics: Brain Neoplasms; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosome | 2022 |
Characteristics of Anaplastic Oligodendrogliomas Short-Term Survivors: A POLA Network Study.
Topics: Brain Neoplasms; Chromosome Aberrations; Humans; Oligodendroglioma; Retrospective Studies; Survivors | 2022 |
Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs.
Topics: Animals; Apoptosis; BRCA2 Protein; Cell Death; CHO Cells; Chromosome Aberrations; Cricetinae; Cricet | 2009 |
Base excision repair as a therapeutic target in colon cancer.
Topics: Animals; Antineoplastic Agents, Alkylating; Base Pair Mismatch; Bone Marrow Diseases; Chromosome Abe | 2002 |
Distinct responses of xenografted gliomas to different alkylating agents are related to histology and genetic alterations.
Topics: Animals; Antineoplastic Agents, Alkylating; Carboplatin; Carmustine; Chromosome Aberrations; Dacarba | 2004 |
Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components.
Topics: Antineoplastic Agents, Alkylating; Blotting, Northern; Cell Division; Cell Survival; Chromosome Aber | 2001 |