Compounds > temoporfin
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temoporfin and Neoplasms

temoporfin has been researched along with Neoplasms in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (11.11)18.2507
2000's7 (25.93)29.6817
2010's15 (55.56)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Hirohara, S; Ito, H; Kakiuchi, K; Kawai, T; Kawaichi, M; Matsui, H; Obata, M; Oka, C; Tamura, M; Tanihara, M; Totani, M; Yuasa, J1
Li, ZT; Liu, YY; Ma, D; Mao, W; Wang, H; Wang, ZK; Wu, Y; Xu, ZY; Zhang, DW; Zhao, Z1
Albrecht, V; Dragicevic, N; Fahr, A; Nikolic, B1
Atkins, A; Haimov-Talmoud, E; Harel, Y; Lellouche, JP; Motiei, M; Popovtzer, R; Schori, H; Shefi, O1
Chen, Y; Feng, S; Gao, F; Liu, W; Wu, J1
Bezdetnaya, L; Lamy, L; Lassalle, HP; Millard, M; Wiehe, A; Yakavets, I; Yankovsky, I; Zorin, V1
Aresh, W; Chen, CW; Lai, PS; Nieh, MP; Tahmasbi Rad, A; Xia, Y1
Alberto, ME; Marino, T; Quartarolo, AD; Russo, N1
Paszko, E; Rogers, L; Senge, MO; Sergeeva, NN; Vaz, GM1
Bastien, E; Bezdetnaya, L; Gräfe, S; Khludeyev, I; Lassalle, HP; Yakavets, I; Yankovsky, I; Zorin, V1
Barberi-Heyob, M; Bastogne, T; Didelon, J; Frochot, C; Gravier, J; Guillemin, F; Schmitt, F; Schneider, R1
Foster, TH; Mitra, S; Wang, KK1
Bhandari, R; Brookes, JA; Hamdoon, Z; Hopper, C; Jerjes, W; Mackay, S; Morley, S; Mosse, CA; Nhembe, F; Shah, P; Upile, T1
Hamdoon, Z; Hoonjan, P; Hopper, C; Jerjes, W; Upile, T1
Allison, RR; Bagnato, VS; Sibata, CH1
Bezdetnaya, L; Bressenot, A; Foster, TH; Garrier, J; Gräfe, S; Guillemin, F; Marchal, S; Mitra, S1
Amelink, A; de Bruijn, HS; de Visscher, SA; Kaščáková, S; Robinson, DJ; Roodenburg, JL; Sterenborg, HJ; van den Heuvel, Av; Witjes, MJ1
Brault, D; Friaa, O; Maillard, P1
Chang, YC; Hsieh, WY; Hsu, CY; Hsu, YH; Lai, PS; Rajan, YC; Syu, WJ; Wang, CH; Yu, HP1
Senge, MO1
Aubert, S; Bolotine, L; Burgos, P; Carré, MC; Even, P; Frochot, C; Guillemin, F; Merlin, JL; Teiten, MH; Viriot, ML1
Bezdetnaya, L; Guillemin, F; Maugain, E; Merlin, JL; Sasnouski, S; Zorin, V1
Baas, P; Out, R; Ruevekamp, M; Schellens, J; Stewart, FA; Triesscheijn, M; Van Berkel, TJ1
Dougherty, TJ1
Altermatt, HJ; Althaus, U; Giger, A; Krueger, T; Lim, CK; Ris, HB; Stewart, JC1
Einarsdóttir, O; Howe, L; Sucheta, A; Zhang, JZ1
Blant, SA; Braichotte, D; Forrer, M; Glanzmann, T; Grosjean, P; Monnier, P; van den Bergh, H; Wagnières, G; Woodtli, A1

Reviews

3 review(s) available for temoporfin and Neoplasms

ArticleYear
Future of oncologic photodynamic therapy.
    Future oncology (London, England), 2010, Volume: 6, Issue:6

    Topics: Aminolevulinic Acid; Dihematoporphyrin Ether; Forecasting; Humans; Mesoporphyrins; Nanoparticles; Neoplasms; Oxygen; Photochemotherapy; Photosensitizing Agents

2010
mTHPC--a drug on its way from second to third generation photosensitizer?
    Photodiagnosis and photodynamic therapy, 2012, Volume: 9, Issue:2

    Topics: Humans; Mesoporphyrins; Neoplasms; Photochemotherapy; Photosensitizing Agents

2012
Photodynamic therapy.
    Photochemistry and photobiology, 1993, Volume: 58, Issue:6

    Topics: Aminolevulinic Acid; Clinical Trials as Topic; Dihematoporphyrin Ether; Humans; Lasers; Mesoporphyrins; Neoplasms; Photochemotherapy; Photosensitizing Agents

1993

Trials

2 trial(s) available for temoporfin and Neoplasms

ArticleYear
Ultrasound-guided photodynamic therapy for deep seated pathologies: prospective study.
    Lasers in surgery and medicine, 2009, Volume: 41, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brachytherapy; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Lasers, Semiconductor; Male; Mesoporphyrins; Middle Aged; Neoplasms; Photochemotherapy; Photosensitizing Agents; Prospective Studies; Treatment Outcome; Ultrasonography, Interventional; Young Adult

2009
The pharmacokinetic behavior of the photosensitizer meso-tetra-hydroxyphenyl-chlorin in mice and men.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:1

    Topics: Animals; Antineoplastic Agents; Apolipoproteins E; Area Under Curve; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Half-Life; Head and Neck Neoplasms; Humans; Injections, Intravenous; Lipoproteins; Lipoproteins, HDL; Lipoproteins, VLDL; Mesoporphyrins; Mice; Mice, Inbred BALB C; Mice, Knockout; Neoplasms; Photochemotherapy; Photosensitizing Agents; Scavenger Receptors, Class B; Species Specificity; Tissue Distribution

2007

Other Studies

22 other study(ies) available for temoporfin and Neoplasms

ArticleYear
Synthesis, Photophysical Properties, and Biological Evaluation of trans-Bisthioglycosylated Tetrakis(fluorophenyl)chlorin for Photodynamic Therapy.
    Journal of medicinal chemistry, 2015, Nov-12, Volume: 58, Issue:21

    Topics: Animals; Breast; Breast Neoplasms; Cell Line, Tumor; Female; Halogenation; Humans; Hydrocarbons, Chlorinated; Mice; Mice, Inbred BALB C; Neoplasms; Photochemotherapy; Photosensitizing Agents

2015
Self-assembled nanoparticles based on supramolecular-organic frameworks and temoporfin for an enhanced photodynamic therapy
    Journal of materials chemistry. B, 2022, 02-09, Volume: 10, Issue:6

    Topics: Animals; Mesoporphyrins; Mice; Nanoparticles; Neoplasms; Photochemotherapy

2022
Biodistribution of the photosensitizer temoporfin after in vivo topical application of temoporfin-loaded invasomes in mice bearing subcutaneously implanted HT29 tumor.
    International journal of pharmaceutics, 2022, Dec-15, Volume: 629

    Topics: Animals; Humans; Liposomes; Mesoporphyrins; Mice; Neoplasms; Particle Size; Photochemotherapy; Photosensitizing Agents; Tissue Distribution

2022
Magnetic Targeting of mTHPC To Improve the Selectivity and Efficiency of Photodynamic Therapy.
    ACS applied materials & interfaces, 2019, Dec-11, Volume: 11, Issue:49

    Topics: Animals; Biocompatible Materials; Cell Line, Tumor; Cell Proliferation; Cerium; Ferric Compounds; Humans; Magnetics; Magnetite Nanoparticles; Mesoporphyrins; Mice; Neoplasms; Photochemotherapy; Photosensitizing Agents; Xenograft Model Antitumor Assays

2019
Targeting integrin-rich tumors with temoporfin-loaded vitamin-E-succinate-grafted chitosan oligosaccharide/d-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles to enhance photodynamic therapy efficiency.
    International journal of pharmaceutics, 2017, Aug-07, Volume: 528, Issue:1-2

    Topics: Animals; Chitosan; Integrins; Mesoporphyrins; Mice; Mice, Nude; Nanoparticles; Neoplasms; Photochemotherapy; Polyethylene Glycols; Succinates; Vitamin E

2017
The alteration of temoporfin distribution in multicellular tumor spheroids by β-cyclodextrins.
    International journal of pharmaceutics, 2017, Aug-30, Volume: 529, Issue:1-2

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrins; Drug Carriers; HT29 Cells; Humans; Mesoporphyrins; Neoplasms; Spheroids, Cellular

2017
Combinational Effects of Active Targeting, Shape, and Enhanced Permeability and Retention for Cancer Theranostic Nanocarriers.
    ACS applied materials & interfaces, 2019, Mar-20, Volume: 11, Issue:11

    Topics: Animals; Cell Line, Tumor; Cell Survival; Drug Carriers; Endocytosis; Female; Folic Acid; Humans; Light; Lipids; Mesoporphyrins; Mice; Mice, Nude; Micelles; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Theranostic Nanomedicine; Transplantation, Heterologous

2019
Photophysical origin of the reduced photodynamic therapy activity of temocene compared to Foscan®: insights from theory.
    Physical chemistry chemical physics : PCCP, 2013, Oct-14, Volume: 15, Issue:38

    Topics: Humans; Mesoporphyrins; Neoplasms; Photochemotherapy; Photosensitizing Agents; Porphyrins; Quantum Theory; Singlet Oxygen

2013
Lead Structures for Applications in Photodynamic Therapy. 6. Temoporfin Anti-Inflammatory Conjugates to Target the Tumor Microenvironment for In Vitro PDT.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Anti-Inflammatory Agents; Humans; In Vitro Techniques; Mesoporphyrins; Neoplasms; Photochemotherapy; Photosensitizing Agents; Tumor Microenvironment

2015
Inclusion complexation with β-cyclodextrin derivatives alters photodynamic activity and biodistribution of meta-tetra(hydroxyphenyl)chlorin.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Aug-25, Volume: 91

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; beta-Cyclodextrins; Blood Proteins; Female; HT29 Cells; Humans; Kidney; Liver; Mesoporphyrins; Mice; Muscles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Skin

2016
Improvement of meta-tetra(hydroxyphenyl)chlorin-like photosensitizer selectivity with folate-based targeted delivery. synthesis and in vivo delivery studies.
    Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13

    Topics: Animals; Carrier Proteins; Cell Line, Tumor; Drug Delivery Systems; Female; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation; Humans; Mesoporphyrins; Mice; Mice, Nude; Molecular Structure; Neoplasms; Photochemistry; Photosensitizing Agents; Receptors, Cell Surface; Spectrophotometry; Xenograft Model Antitumor Assays

2008
Photodynamic dose does not correlate with long-term tumor response to mTHPC-PDT performed at several drug-light intervals.
    Medical physics, 2008, Volume: 35, Issue:8

    Topics: Algorithms; Animals; Computer Simulation; Disease Models, Animal; Mesoporphyrins; Mice; Models, Biological; Neoplasms; Photochemotherapy; Photosensitizing Agents; Radiation Dosage; Singlet Oxygen; Time Factors

2008
Endoluminal carotid stenting prior to photodynamic therapy to pericarotid malignant disease: technical advance.
    Photodiagnosis and photodynamic therapy, 2010, Volume: 7, Issue:2

    Topics: Angioplasty; Carotid Artery Diseases; Carotid Stenosis; Humans; Mesoporphyrins; Neoplasms; Photochemotherapy; Photosensitizing Agents; Stents

2010
Compartmental targeting for mTHPC-based photodynamic treatment in vivo: Correlation of efficiency, pharmacokinetics, and regional distribution of apoptosis.
    International journal of radiation oncology, biology, physics, 2010, Oct-01, Volume: 78, Issue:2

    Topics: Animals; Apoptosis; Caspase 3; Collagen Type IV; Female; Immunohistochemistry; Mesoporphyrins; Mice; Mice, Inbred BALB C; Necrosis; Neoplasm Proteins; Neoplasms; Photochemotherapy; Photosensitizing Agents; Tissue Distribution; Xenograft Model Antitumor Assays

2010
Fluorescence localization and kinetics of mTHPC and liposomal formulations of mTHPC in the window-chamber tumor model.
    Lasers in surgery and medicine, 2011, Volume: 43, Issue:6

    Topics: Animals; Female; Fluorescence; Liposomes; Mesoporphyrins; Neoplasm Transplantation; Neoplasms; Rats; Rats, Inbred F344

2011
Reaction of the m-THPC triplet state with the antioxidant Trolox and the anesthetic Propofol: modulation of photosensitization mechanisms relevant to photodynamic therapy?
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2012, Volume: 11, Issue:4

    Topics: Anesthetics; Antioxidants; Chromans; Humans; Kinetics; Lasers; Mesoporphyrins; Neoplasms; Oxidation-Reduction; Photochemotherapy; Photolysis; Photosensitizing Agents; Propofol; Reactive Oxygen Species

2012
Improved photodynamic cancer treatment by folate-conjugated polymeric micelles in a KB xenografted animal model.
    Small (Weinheim an der Bergstrasse, Germany), 2012, Jul-09, Volume: 8, Issue:13

    Topics: Animals; Cell Line, Tumor; Female; Folic Acid; Humans; Mesoporphyrins; Mice; Micelles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Polymers

2012
Specific fluorescent tracers. Imaging and applications for photodynamic therapy.
    Comptes rendus biologies, 2002, Volume: 325, Issue:4

    Topics: Biological Transport; Breast Neoplasms; Cell Survival; DNA, Neoplasm; Drug Resistance, Neoplasm; Female; Fluorescent Dyes; Glycosylation; Humans; Lysosomes; Mesoporphyrins; Microscopy, Fluorescence; Neoplasms; Photochemotherapy; Porphyrins; Radiation-Sensitizing Agents; Subcellular Fractions; Tumor Cells, Cultured

2002
Foscan-based photodynamic treatment in vivo: correlation between efficacy and Foscan accumulation in tumor, plasma and leukocytes.
    Oncology reports, 2004, Volume: 12, Issue:3

    Topics: Animals; Cell Line, Tumor; Female; Flow Cytometry; Kinetics; Leukocytes; Light; Mesoporphyrins; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Oxygen; Partial Pressure; Photochemotherapy; Photosensitizing Agents; Time Factors; Treatment Outcome

2004
Photodynamic therapy with mTHPC and polyethylene glycol-derived mTHPC: a comparative study on human tumour xenografts.
    British journal of cancer, 1999, Volume: 79, Issue:7-8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Dermatitis, Phototoxic; Humans; Mesoporphyrins; Mesothelioma; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Photochemotherapy; Polyethylene Glycols; Radiation-Sensitizing Agents; Transplantation, Heterologous

1999
Time-resolved studies of the excited-state dynamics of meso-tetra(hydroxylphenyl)chlorin in solution.
    Photochemistry and photobiology, 1999, Volume: 69, Issue:6

    Topics: Antineoplastic Agents; Humans; Mesoporphyrins; Neoplasms; Photochemistry; Photochemotherapy; Photosensitizing Agents; Spectrophotometry; Thermodynamics

1999
Pharmacokinetics and pharmacodynamics of tetra(m-hydroxyphenyl)chlorin in the hamster cheek pouch tumor model: comparison with clinical measurements.
    Journal of photochemistry and photobiology. B, Biology, 2000, Volume: 57, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cricetinae; Drug Screening Assays, Antitumor; Humans; Light; Mesocricetus; Mesoporphyrins; Mouth Mucosa; Neoplasms; Photochemotherapy; Photosensitizing Agents; Species Specificity; Tissue Distribution

2000