temiverine has been researched along with Urinary Incontinence in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 20 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, S; Kimura, K; Natsukawa, T; Ukai, Y; Yoshikuni, Y | 1 |
| Iwakura, K; Nakazawa, M; Nishiguchi, Y; Oka, T; Sumi, N; Tarui, M; Yoshida, M | 1 |
| Iwakura, K; Katsumata, T; Kobayashi, J; Moro, M; Nishiguchi, Y; Nishimura, N; Sumi, N | 1 |
| Adachi, T; Ishibashi, S; Iwakura, K; Kitayama, E; Nakazawa, M; Nishiguchi, Y; Sumi, N; Tawaratani, T; Uchimoto, H; Yoshida, M | 1 |
| Baba, S; Chihaya, Y; Ikeda, H; Ishibashi, S; Iwakura, K; Nagata, R; Okasaki, K; Satake, S; Sumi, N | 1 |
| Furukawa, S; Ishibashi, S; Iwakura, K; Kikumori, M; Kouyama, H; Nishimori, T; Sumi, N; Taniguchi, Y | 1 |
| Adachi, T; Ishibashi, S; Iwakura, K; Kitayama, E; Nakazawa, M; Oka, T; Sumi, N; Tawaratani, T; Yoshida, M | 1 |
| Adachi, T; Ishibashi, S; Iwakura, K; Kawaminami, A; Kitayama, E; Nakazawa, M; Oka, T; Sumi, N; Tawaratani, T; Yoshida, M | 1 |
| Adachi, T; Ishibashi, S; Iwakura, K; Kajihara, T; Kitayama, E; Nakazawa, M; Sumi, N; Yoshida, M; Yoshikawa, K | 1 |
| Adachi, T; Ishibashi, S; Iwakura, K; Kawaguchi, K; Nakazawa, M; Sumi, N; Tamura, H; Tawaratani, T; Wakabayashi, K; Yoshida, M | 1 |
| Ninomiya, H; Schardein, JL; Sumi, N; Watanabe, M; York, RG | 4 |
| Ajimi, S; Inai, T; Kajiwara, Y; Kakimoto, K; Kikuno, T; Ogura, S; Otsuka, M; Shimazaki, H; Sumi, N; Tamura, H; Watanabe, M | 1 |
| Iwakura, K; Kitayama, E; Sumi, N; Tamura, H; Watanabe, M; Yamashita, Y | 1 |
| Hatch, RC; Ishibashi, S; Iwakura, K; Nakazawa, M; Regan, KS; Sumi, N | 2 |
| Fujisawa, H; Kimura, K; Nagata, R; Ohnishi, M; Okasaki, K; Samejima, H | 1 |
| Hamada, K; Kimura, K; Kimura, Y; Sasaki, Y; Seto, T; Ukai, Y; Yamazaki, C; Yoshikuni, Y | 1 |
20 other study(ies) available for temiverine and Urinary Incontinence
| Article | Year |
|---|---|
Inhibitory effects of NS-21, a novel drug for urinary incontinence, and its active metabolite, RCC-36, on L-type calcium currents in isolated guinea pig detrusor smooth muscle cells.
Topics: Animals; Butylamines; Calcium; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle, Smooth; Parasympatholytics; Patch-Clamp Techniques; Phenylacetates; Urinary Bladder; Urinary Incontinence | 1997 |
[Single-dose toxicity studies of (+/-)-4-diethylamino-1, 1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate(NS-21), a novel drug for urinary frequency and incontinence, in mice, rats and dogs].
Topics: Animals; Dogs; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Male; Mice; Molecular Structure; Phenylacetates; Rats; Rats, Sprague-Dawley; Urinary Incontinence; Urination Disorders | 1997 |
[Intraperitoneal single-dose toxicity studies of active metabolite, optical isomers, hydrolysis products and bi-product of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate(NS-21), a novel
Topics: Animals; Dose-Response Relationship, Drug; Female; Hydrolysis; Injections, Intraperitoneal; Isomerism; Lethal Dose 50; Male; Mice; Molecular Structure; Phenylacetates; Urinary Incontinence; Urination Disorders | 1997 |
[A 13-week oral repeated dose toxicity study of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a novel drug for urinary frequency and incontinence, in rats followed by a 5-week
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Male; Molecular Structure; Phenylacetates; Rats; Rats, Sprague-Dawley; Time Factors; Urinary Incontinence; Urination Disorders | 1997 |
[A 26-week oral repeated dose toxicity study of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a novel drug for urinary frequency and incontinence, in rats followed by a 9-week
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Male; Phenylacetates; Rats; Rats, Sprague-Dawley; Time Factors; Urinary Incontinence; Urination Disorders | 1997 |
[Oral single-dose and 13-week repeat-dose toxicity studies of RCC-36, the active metabolite of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate(NS-21), a novel drug for urinary frequency a
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Male; Phenylacetates; Rats; Rats, Sprague-Dawley; Urinary Incontinence; Urination Disorders | 1997 |
[A 13-week oral repeated dose toxicity study of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a novel drug for urinary frequency and incontinence, in dogs followed by a 5-week
Topics: Administration, Oral; Animals; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Male; Molecular Structure; Phenylacetates; Time Factors; Urinary Incontinence; Urination Disorders | 1997 |
[A 12-month oral repeated dose toxicity study of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a novel drug for urinary frequency and incontinence, in dogs followed by a 2-mont
Topics: Administration, Oral; Animals; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Liver; Male; Molecular Structure; Phenylacetates; Time Factors; Urinary Incontinence; Urination Disorders | 1997 |
[Toxicokinetics of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a novel drug for urinary frequency and incontinence, in mice and rats during 13-week dietary administration].
Topics: Administration, Oral; Animals; Body Weight; Diet; Female; Male; Mice; Molecular Structure; Phenylacetates; Rats; Rats, Inbred F344; Time Factors; Urinary Incontinence; Urination Disorders | 1997 |
[The mechanism of increased thyroidal function caused by (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate(NS-21), a novel drug for urinary frequency and incontinence, administration in rat
Topics: Animals; Glucuronosyltransferase; Microsomes, Liver; Phenylacetates; Rats; Thyroid Gland; Thyrotropin; Thyroxine; Uridine Diphosphate Glucuronic Acid; Urinary Incontinence; Urination Disorders | 1997 |
[Reproductive and developmental toxicity studies of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate(NS-21), a novel drug for urinary frequency and incontinence (1). Fertility study in rat
Topics: Administration, Oral; Animals; Embryonic and Fetal Development; Female; Fertility; Fetus; Male; Phenylacetates; Pregnancy; Rats; Reproduction; Urinary Incontinence; Urination Disorders | 1997 |
[Reproductive and developmental toxicity studies of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate(NS-21), a novel drug for urinary frequency and incontinence (2). Teratogenicity study i
Topics: Administration, Oral; Animals; Animals, Newborn; Embryonic and Fetal Development; Female; Fetus; Male; Molecular Structure; Phenylacetates; Pregnancy; Rats; Reproduction; Teratogens; Urinary Incontinence; Urination Disorders | 1997 |
[Reproductive and developmental toxicity studies of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate(NS-21), a novel drug for urinary frequency and incontinence (3). Teratogenicity study i
Topics: Administration, Oral; Animals; Embryonic and Fetal Development; Female; Male; Molecular Structure; Phenylacetates; Pregnancy; Rabbits; Reproduction; Teratogens; Urinary Incontinence; Urination Disorders | 1997 |
[Reproductive and developmental toxicity studies of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate(NS-21), a novel drug for urinary frequency and incontinence (4). Perinatal and postnata
Topics: Administration, Oral; Animals; Animals, Newborn; Embryonic and Fetal Development; Female; Humans; Infant, Newborn; Male; Phenylacetates; Pregnancy; Rats; Reproduction; Teratogens; Urinary Incontinence; Urination Disorders | 1997 |
[Mutagenicity studies of (+/-)-4-diethylamino-1,1,-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a novel drug for urinary frequency and incontinence].
Topics: Animals; Cells, Cultured; Chromosomes; Cricetinae; Escherichia coli; Male; Mice; Micronucleus Tests; Mutagenicity Tests; Mutagens; Phenylacetates; Salmonella typhimurium; Urinary Incontinence; Urination Disorders | 1997 |
[Mutagenicity studies of RCC-36, the active metabolite of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a novel drug for urinary frequency and incontinence].
Topics: Animals; Cells, Cultured; Cricetinae; Erythrocytes; Escherichia coli; Male; Mice; Molecular Structure; Mutagenicity Tests; Mutagens; Phenylacetates; Salmonella typhimurium; Urinary Incontinence; Urination Disorders | 1997 |
Seventy-eight-week dietary carcinogenicity study of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a novel drug for urinary frequency and incontinence, in mice.
Topics: Administration, Oral; Animals; Carcinogenicity Tests; Carcinogens; Diet; Female; Male; Mice; Molecular Structure; Phenylacetates; Time Factors; Urinary Incontinence; Urination Disorders | 1997 |
Two-year dietary carcinogenicity study of (+/-)-4-diethylamino-1, 1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a novel drug for urinary frequency and incontinence, in rats.
Topics: Administration, Oral; Animals; Carcinogenicity Tests; Carcinogens; Diet; Female; Liver; Male; Molecular Structure; Phenylacetates; Rats; Rats, Inbred F344; Thyroid Gland; Time Factors; Urinary Incontinence; Urination Disorders | 1997 |
[Antigenicity study of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a novel drug for urinary frequency and incontinence].
Topics: Animals; Guinea Pigs; Hemagglutination Tests; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Phenylacetates; Rats; Urinary Incontinence; Urination Disorders | 1997 |
Effect of NS-21, an anticholinergic drug with calcium antagonistic activity, on lower urinary tract function in a rat model of urinary frequency.
Topics: Animals; Atropine; Benzilates; Calcium Channel Blockers; Denervation; Disease Models, Animal; Flavoxate; Hypogastric Plexus; Male; Mandelic Acids; Parasympatholytics; Phenylacetates; Rats; Rats, Sprague-Dawley; Urinary Bladder; Urinary Incontinence | 1997 |