Page last updated: 2024-11-04

temazepam and Chronic Insomnia

temazepam has been researched along with Chronic Insomnia in 90 studies

Temazepam: A benzodiazepine that acts as a GAMMA-AMINOBUTYRIC ACID modulator and anti-anxiety agent.

Research Excerpts

ExcerptRelevanceReference
"This study reports on the incidence of adverse effects of temazepam in older adults with chronic insomnia and examines whether the addition of cognitive-behaviour therapy (CBT) is associated with less drug used and fewer adverse effects."9.10Adverse effects of temazepam in older adults with chronic insomnia. ( Bastien, CH; Brink, D; Brown, TR; Morin, CM, 2003)
"This randomised controlled trial was conducted to compare zolpidem to an equivalent dose of temazepam with respect to subjective rebound insomnia after cessation of 4 weeks of treatment in chronic insomnia (zolpidem 10 mg, n=79; temazepam 20 mg, n=84)."5.11Zolpidem is not superior to temazepam with respect to rebound insomnia: a controlled study. ( van Balkom, AJ; Voshaar, RC; Zitman, FG, 2004)
"This study reports on the incidence of adverse effects of temazepam in older adults with chronic insomnia and examines whether the addition of cognitive-behaviour therapy (CBT) is associated with less drug used and fewer adverse effects."5.10Adverse effects of temazepam in older adults with chronic insomnia. ( Bastien, CH; Brink, D; Brown, TR; Morin, CM, 2003)
" Only few controlled studies have characterized the effect of discontinuation of their chronic use on sleep and quality of life."2.90Withdrawal from long-term use of zopiclone, zolpidem and temazepam may improve perceived sleep and quality of life in older adults with primary insomnia. ( Kivelä, SL; Lähteenmäki, R; Neuvonen, PJ; Partinen, M; Puustinen, J; Räihä, I; Vahlberg, T, 2019)
"92 outpatients (≥55 years) with primary insomnia, long-term BZDA use as hypnotics (mean duration of BZDA use 9."2.87Long-term persistence of withdrawal of temazepam, zopiclone, and zolpidem in older adults: a 3-year follow-up study. ( Aarnio, P; Kivelä, SL; Lähteenmäki, R; Neuvonen, PJ; Nurminen, J; Partinen, M; Puustinen, J; Räihä, I; Vahlberg, T, 2018)
"Withdrawal from long-term use of benzodiazepines can rapidly improve muscle strength and balance."2.79Handgrip strength and balance in older adults following withdrawal from long-term use of temazepam, zopiclone or zolpidem as hypnotics. ( Kivelä, SL; Lähteenmäki, R; Lyles, A; Neuvonen, PJ; Nurminen, J; Partinen, M; Puustinen, J; Räihä, I; Vahlberg, T, 2014)
"Thirty-eight insomniacs took part in a 5-week, double-blind, placebo-controlled study of the effects of 2 weeks of administration of temazepam 20 mg on sleep."2.71Evaluation of actigraphy and automated telephoned questionnaires to assess hypnotic effects in insomnia. ( Nutt, DJ; Potokar, J; Rich, AS; Rich, NC; Wilson, SJ, 2004)
"Occasionally, insomniac patients may take a sleeping pill after midnight."2.71Effects of after-midnight intake of zolpidem and temazepam on driving ability in women with non-organic insomnia. ( Halavaara, M; Hiltunen, H; Hirvonen, K; Hublin, C; Partinen, M, 2003)
"Temazepam was well tolerated, and no significant differences between doses were found for adverse event (AE) incidence, mean score on the Digit Symbol Substitution Task, or mean scores on questions related to tolerability from the Leeds Sleep Evaluation Questionnaire."2.71Comparison of temazepam 7.5 mg with temazepam 15 mg for the treatment of transient insomnia. ( Erman, MK; Loewy, D; Scharf, MB, 2004)
"Hypnograms from 21 patients with primary insomnia were collected during a randomized, placebo-controlled crossover study of 20 mg temazepam."2.69A pharmacodynamic Markov mixed-effects model for the effect of temazepam on sleep. ( Cohen, AF; Danhof, M; Karlsson, MO; Kemp, B; Peck, CC; Schoemaker, RC; Tuk, B; van Gerven, JM, 2000)
"Insomnia is a prevalent health complaint in older adults."2.69Behavioral and pharmacological therapies for late-life insomnia: a randomized controlled trial. ( Brink, D; Colecchi, C; Morin, CM; Sood, R; Stone, J, 1999)
"A transient insomnia model, the "first night" effect in the sleep laboratory, was used to assess the dose range for the hypnotic and sleep stage effects of temazepam."2.67Dose effects of temazepam in transient insomnia. ( Roehrs, T; Roth, T; Sterling, W; Vogel, G, 1990)
"Zopiclone is an effective hypnotic comparable to temazepam."2.67A double-blind placebo-controlled trial of zopiclone 7.5 mg and temazepam 20 mg in insomnia. ( Hassan, R; Ngen, CC, 1990)
"With temazepam this effect was more variable, with total wake time increased only with the second withdrawal period (39%)."2.67Rebound insomnia after only brief and intermittent use of rapidly eliminated benzodiazepines. ( Bixler, EO; Fee, EC; Kales, A; Manfredi, RL; Vela-Bueno, A; Vgontzas, AN, 1991)
"Temazepam was consistently less potent than chlormethiazole on tests of drowsiness and psychomotor performance."2.67A single-dose study of the pharmacodynamic effects of chlormethiazole, temazepam and placebo in elderly parkinsonian patients. ( Ashwood, TJ; Bateman, DN; Tulloch, JA; Woodhouse, KW, 1991)
"There was no rebound insomnia when temazepam was withdrawn either abruptly or gradually in long-term hospitalised elderly patients and may not be effective as a long-term hypnotic."2.66Temazepam withdrawal in elderly hospitalized patients: a double blind randomised trial comparing abrupt versus gradual withdrawal. ( Brown, H; Taggart, HM; Tham, TC, 1989)
"Temazepam did not produce any behavioral side effects during either drug condition."2.66Quazepam and temazepam: effects of short- and intermediate-term use and withdrawal. ( Bixler, EO; Jacoby, JA; Kales, A; Kales, JD; Soldatos, CR; Vela-Bueno, A, 1986)
"With chlormethiazole treatment there was no daytime drowsiness, whereas significant daytime drowsiness occurred with temazepam."2.66A double-blind comparison of chlormethiazole and temazepam in elderly patients with sleep disturbances. ( Bayer, AJ; Pathy, MS; Stoker, MJ, 1986)
" Dosing lasted 7 days."2.66Saccadic eye movements as a measure of residual effects: temazepam compared with other hypnotics. ( Hofferberth, B, 1986)
"Zopiclone was associated with feelings of being troubled, tense, antagonistic and bored whereas temazepam produced drowsiness, clumsiness, dreaminess and sadness."2.66Subjective effects during administration and on discontinuation of zopiclone and temazepam in normal subjects. ( Frcka, G; Lader, M, 1987)
"Midazolam (15 mg) was compared with temazepam (30 mg) in a randomized, double-blind, parallel group study."2.66Efficacy without tolerance or rebound insomnia for midazolam and temazepam after use for one to three months. ( Allen, RP; Chernik, DA; Hoddes, E; Mendels, J; Nevins, DB, 1987)
"In it, 12 female formerly diagnosed insomniacs and hypnotic users acted as subjects."2.66Hypnotics and actual driving performance. ( O'Hanlon, JF; Volkerts, ER, 1986)
"The aetiology of insomnia can be conveniently divided into six groups: physical (pain, cough, etc."2.66Insomnia in general practice: the role of temazepam and a comparison with zopiclone. ( Wheatley, D, 1986)
"Sixty Filipino insomniacs participated in a double-blind study of temazepam on an outpatient basis."2.65Treatment of insomnia with temazepam: double-blind, placebo-controlled evaluation. ( Cuanang, JR; Limos, L, 1982)
"Experimental sleep disturbances (model insomnia) were produced by the administration of methylphenidate (MPD) 10 mg and caffeine (CAF) 150 mg."2.65Model insomnia by methylphenidate and caffeine and use in the evaluation of temazepam. ( Matsue, Y; Matsuoka, H; Okuma, T; Toyomura, K, 1982)
"Fifty-five patients complaining of insomnia entered a single-blind general practice study and were treated with either 400 mg chlormezanone or 20 mg temazepam at night for 2 weeks."2.65A comparison of chlormezanone and temazepam in sleep disturbance. ( Van Steenis, D, 1982)
"Seventy insomniac patients, previously unresponsive to conventional hypnotic dosage, were treated for seven nights with temazepam in 20 mg soft gelatin capsules (Euhypnos Forte)."2.65Euhypnos Forte (temazepam) for resistant insomnia: a clinical trial. ( Moon, CA; Schiller, M, 1979)
"1 Temazepam was evaluated in a strictly defined insomniac patient population under sleep laboratory conditions."2.65Hypnotic efficacy of temazepam: a long-term sleep laboratory evaluation. ( Carskadon, MA; Dement, WC; Guilleminault, C; Mitler, MM; Phillips, RL; Spiegel, R; Sterling, WR; Zarcone, VP, 1979)
" Other agents commonly used at sea-level such as eszopiclone and diphenhydramine have not been studied at high altitude but are likely safe to use given their mechanism of action and known side effects."2.44Which medications are safe and effective for improving sleep at high altitude? ( Luks, AM, 2008)
"Up to 40% of adults have insomnia, with difficulty getting to sleep, early waking, or feeling unrefreshed on waking."2.44Insomnia in the elderly. ( Lilly, J; Montgomery, P, 2007)
"Patients with insomnia are characterised by excessive arousal and an inability to sleep despite reported reduced sleep hours and poor sleep quality."2.41Insomnia. Diagnosis and management. ( Grunstein, R, 2002)
"The risk of rebound insomnia is greater with the short half-life as compared with the long half-life benzodiazepines."2.38Rebound insomnia: a critical review. ( Gillin, JC; Johnson, LC; Spinweber, CL, 1989)
"Consequently, while the majority of insomniac patients complain primarily of difficulty falling asleep, temazepam is not effective for this sleep complaint."2.36Sleep laboratory studies of hypnotic drugs: efficacy and withdrawal effects. ( Kales, A; Kales, JD, 1983)
"Ninety-two adults (age ≥55 years) with primary insomnia and who were long-term daily users of BZD volunteered to participate in a 1-month medically supported withdrawal attempt from BZD use, with a subsequent 5-month follow-up."1.40Effect of withdrawal from long-term use of temazepam, zopiclone or zolpidem as hypnotic agents on cognition in older adults. ( Kivelä, SL; Lähteenmäki, R; Lyles, A; Neuvonen, PJ; Partinen, M; Polo-Kantola, P; Puustinen, J; Räihä, I; Salo, P; Vahlberg, T, 2014)
"Transient insomnia was induced in the sleep laboratory by means of the 'first night' effect and by implementing a 2-h phase advance."1.33Effects of temazepam 7.5 mg and temazepam 15 mg on sleep maintenance and sleep architecture in a model of transient insomnia. ( Erman, MK; Loewy, DB; Scharf, MB, 2005)
"(1) In chronic insomnia, cognitive-behaviour treatments appear to be as effective as benzodiazepines."1.31Behaviour therapy for chronic insomnia. ( , 2001)
"All were within 1-3 weeks of trauma exposure and had acute PTSD symptoms that included disturbed sleep."1.30Pilot evaluation of hypnotic medication during acute traumatic stress response. ( Augenstein, JS; Byers, PM; Mellman, TA, 1998)
"The correlation between the pharmacodynamic measures and sleep quality was determined in 21 patients with primary insomnia."1.30Pharmacodynamics of temazepam in primary insomnia: assessment of the value of quantitative electroencephalography and saccadic eye movements in predicting improvement of sleep. ( Breimer, DD; Cohen, AF; Danhof, M; Kamphuisen, HA; Kemp, B; Oberyé, JJ; Peck, CC; Pieters, MS; Schoemaker, RC; Tuk, B; van Gerven, J, 1997)
"Temazepam, 7."1.29Temazepam 7.5 mg: effects on sleep in elderly insomniacs. ( Bixler, EO; Kales, A; Myers, DC; Vgontzas, AN, 1994)
"Rates of insomnia visits are somewhat higher for middle-aged (45 to 64 years of age) women, and data for female insomniacs suggest a trend toward diagnoses of depression compared with other (somatic) diagnoses for men."1.29Management of insomnia in office-based practice. National prevalence and therapeutic patterns. ( Brunton, SA; Radecki, SE, 1993)
"An untreated insomnia group also was included."1.28The beneficial and adverse effects of hypnotics. ( Balter, MB; Uhlenhuth, EH, 1991)
"Two noncontinuous sleep disturbances, insomnia in the elderly and transient insomnia in young and middle-aged adults, are probably the most acceptable indications for the use of benzodiazepines."1.28Clinical uses and advantages of low doses of benzodiazepine hypnotics. ( Vogel, G, 1992)
"Side effects involving agitation, e."1.27Agitation observed during treatment with newer hypnotic drugs. ( Regestein, QR; Reich, P, 1985)
"When the various benzodiazepine hypnotics are studied, large differences are seen with regard to their pharmacokinetic properties and metabolism in man."1.27Pharmacokinetics of temazepam compared with other benzodiazepine hypnotics--some clinical consequences. ( Breimer, DD; Jochemsen, R, 1986)
"The relationship of insomnia with the hypoxic environment is undetermined."1.27Hypnotics and transient insomnia. ( Nicholson, AN; Stone, BM, 1986)

Research

Studies (90)

TimeframeStudies, this research(%)All Research%
pre-199052 (57.78)18.7374
1990's16 (17.78)18.2507
2000's18 (20.00)29.6817
2010's4 (4.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Puustinen, J4
Lähteenmäki, R4
Nurminen, J2
Vahlberg, T4
Aarnio, P1
Partinen, M5
Räihä, I4
Neuvonen, PJ4
Kivelä, SL4
Polo-Kantola, P1
Salo, P1
Lyles, A2
Luks, AM1
Montgomery, P1
Lilly, J1
Hislop, J1
Arber, S1
Grunstein, R1
Morin, CM3
Bastien, CH1
Brink, D2
Brown, TR1
Hirvonen, K1
Hublin, C1
Halavaara, M1
Hiltunen, H1
Wilson, SJ1
Rich, AS1
Rich, NC1
Potokar, J1
Nutt, DJ1
Erman, MK2
Loewy, D1
Scharf, MB3
Voshaar, RC1
van Balkom, AJ1
Zitman, FG1
Romasenko, LV1
Parkhomenko, IM1
Loewy, DB1
Iraqi, A1
Hughes, TL1
Glass, JR1
Sproule, BA1
Herrmann, N1
Busto, UE1
Fowler, LK2
Schiller, M2
Linnoila, M1
Viukari, M1
Lamminsivu, U1
Auvinen, J1
Fillingim, JM2
Cuanang, JR1
Limos, L1
Okuma, T2
Matsuoka, H1
Matsue, Y1
Toyomura, K1
Van Steenis, D1
Laffont, F1
Cathala, HP1
Esnault, S1
Gilbert, A1
Minz, M1
Peytourg, MA1
Waisbord, P1
Rickels, K1
Kales, A5
Kales, JD3
Saletu, B1
Grünberger, J1
Anderer, P1
Conell, LJ1
Berlin, RM1
Gringras, M1
Beaumont, G1
Ankier, SI1
Beary, MD1
Lacey, JH1
Crutchfield, MB1
Bhat, AV1
Roehrs, T4
Lamphere, J2
Paxton, C2
Wittig, R2
Zorick, F3
Roth, T5
de Jonghe, F1
Ameling, EH1
Jonkers, F1
Folkers, C1
Schwarz, RV1
Wesnes, K1
Warburton, DM1
Lader, MH1
Hiraga, H1
Ichijo, S1
Vgontzas, AN3
Bixler, EO4
Myers, DC1
Radecki, SE1
Brunton, SA1
Griffith, DN1
Robinson, M1
Tuk, B2
Oberyé, JJ1
Pieters, MS1
Schoemaker, RC2
Kemp, B2
van Gerven, J1
Danhof, M2
Kamphuisen, HA1
Cohen, AF2
Breimer, DD2
Peck, CC2
Mellman, TA1
Byers, PM1
Augenstein, JS1
Colecchi, C1
Stone, J1
Sood, R1
Karlsson, MO1
van Gerven, JM1
Arnedt, JT1
Martin, JL1
Posner, DA1
Ramesh, M1
Roberts, G1
Blais, F1
Savard, J1
Sussman, HS1
Moon, CA1
Mitler, MM2
Carskadon, MA1
Phillips, RL1
Sterling, WR1
Zarcone, VP1
Spiegel, R1
Guilleminault, C1
Dement, WC1
Heffron, WA1
Roth, P1
Nicholson, AN3
Nakra, BR1
Gfeller, JD1
Hassan, R2
Vogel, G3
Manfredi, RL2
Tyson, KL1
Walsh, JK1
Mahowald, MW1
Roehrs, TA1
Tulloch, JA1
Ashwood, TJ1
Bateman, DN1
Woodhouse, KW1
Vela-Bueno, A2
Fee, EC1
Balter, MB1
Uhlenhuth, EH1
Ngen, CC1
Sterling, W1
Gillin, JC1
Spinweber, CL1
Johnson, LC1
Tham, TC1
Brown, H1
Taggart, HM1
Sussman, N1
Wheatley, D2
Hauri, P1
Sateia, M1
Kipp, J1
Regestein, QR1
Reich, P1
Soldatos, CR1
Jacoby, JA1
Allen, RM1
Fancourt, G1
Castleden, M1
Pathy, MS1
Bayer, AJ1
Stoker, MJ1
Vogel, F1
Browman, CP1
Menn, SJ1
Gujavarty, K1
Timms, RM1
Hofferberth, B1
Schmidt, U1
Brendemühl, D1
Rüther, E1
Jochemsen, R1
Hindmarch, I1
Stone, BM2
Lader, M1
Frcka, G1
Meuleman, JR1
Nelson, RC1
Clark, RL1
Allen, RP1
Mendels, J1
Nevins, DB1
Chernik, DA1
Hoddes, E1
Fletcher, K1
Graham, JP1
Smith, PA1
Bradwell, AR1
Coote, JH1
DiBella, GA1
O'Hanlon, JF1
Volkerts, ER1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Development of a Coordinated, Community-Based Medication Management Model for Home-Dwelling Aged in Primary Care[NCT02545257]191 participants (Actual)Interventional2015-09-30Completed
Addressing Nocturnal Sleep/Wake Effects on Risk of Suicide in Older Adults (ANSWERS-OA): A Pilot, Open-Label, Randomized Controlled Trial of Digital Cognitive Behavioral Therapy for Insomnia[NCT04986007]70 participants (Anticipated)Interventional2021-09-01Enrolling by invitation
Treatment of High-altitude Sleep Disturbance: A Double-blind Comparison of Temazepam Versus Acetazolamide.[NCT01519544]34 participants (Actual)Interventional2012-03-31Completed
Efficacy Potential of an Internet-based Sleep Program to Improve Sleep Quality in People With HIV[NCT02571595]27 participants (Actual)Interventional2015-05-31Terminated
Randomized Controlled Trials to Evaluate Health enSuite Insomnia: an App Based Treatment for Adult Chronic Insomnia[NCT04962087]830 participants (Anticipated)Interventional2022-06-29Not yet recruiting
Method of Assessment of Driving Ability in Patients Suffering From Wakefulness Pathologies, Impact of Modafinil Treatment.[NCT00916253]27 participants (Actual)Interventional2010-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for temazepam and Chronic Insomnia

ArticleYear
Which medications are safe and effective for improving sleep at high altitude?
    High altitude medicine & biology, 2008,Fall, Volume: 9, Issue:3

    Topics: Acetamides; Acetazolamide; Altitude Sickness; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazep

2008
Insomnia in the elderly.
    BMJ clinical evidence, 2007, Oct-01, Volume: 2007

    Topics: Aged; Cognitive Behavioral Therapy; Flurazepam; Humans; Risk Factors; Sleep; Sleep Initiation and Ma

2007
Insomnia. Diagnosis and management.
    Australian family physician, 2002, Volume: 31, Issue:11

    Topics: Anti-Anxiety Agents; Azabicyclo Compounds; Cognitive Behavioral Therapy; Humans; Hypnotics and Sedat

2002
Clinical trials of hypnotics.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:2

    Topics: Anti-Anxiety Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Flurazepam; Half-Li

1983
Sleep laboratory studies of hypnotic drugs: efficacy and withdrawal effects.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:2

    Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Dose-Response Relationship, Drug; Fl

1983
Behavioral treatment for chronic insomnia.
    Medicine and health, Rhode Island, 2002, Volume: 85, Issue:3

    Topics: Anti-Anxiety Agents; Behavior Therapy; Chronic Disease; Cognitive Behavioral Therapy; Combined Modal

2002
A review of the safety profiles of benzodiazepine hypnotics.
    The Journal of clinical psychiatry, 1991, Volume: 52 Suppl

    Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Central Nervous System; Flurazepam; Half-Life; Humans; H

1991
Rebound insomnia: a critical review.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:3

    Topics: Anti-Anxiety Agents; Flurazepam; Humans; Sleep Initiation and Maintenance Disorders; Sleep Stages; S

1989

Trials

52 trials available for temazepam and Chronic Insomnia

ArticleYear
Long-term persistence of withdrawal of temazepam, zopiclone, and zolpidem in older adults: a 3-year follow-up study.
    BMC geriatrics, 2018, 06-15, Volume: 18, Issue:1

    Topics: Aged; Azabicyclo Compounds; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypnotics and Se

2018
Withdrawal from long-term use of zopiclone, zolpidem and temazepam may improve perceived sleep and quality of life in older adults with primary insomnia.
    Basic & clinical pharmacology & toxicology, 2019, Volume: 124, Issue:3

    Topics: Aged; Aged, 80 and over; Azabicyclo Compounds; Double-Blind Method; Female; Humans; Hypnotics and Se

2019
Handgrip strength and balance in older adults following withdrawal from long-term use of temazepam, zopiclone or zolpidem as hypnotics.
    BMC geriatrics, 2014, Nov-21, Volume: 14

    Topics: Aged; Aged, 80 and over; Azabicyclo Compounds; Female; Follow-Up Studies; Hand Strength; Humans; Hyp

2014
Adverse effects of temazepam in older adults with chronic insomnia.
    Human psychopharmacology, 2003, Volume: 18, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Cognitive Behavioral Therapy; Combined Modality Therap

2003
Effects of after-midnight intake of zolpidem and temazepam on driving ability in women with non-organic insomnia.
    Sleep medicine, 2003, Volume: 4, Issue:6

    Topics: Arousal; Automobile Driving; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Humans; Hypn

2003
Evaluation of actigraphy and automated telephoned questionnaires to assess hypnotic effects in insomnia.
    International clinical psychopharmacology, 2004, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Cross-Over Studies; Double-Blind Method; Humans; Middl

2004
Comparison of temazepam 7.5 mg with temazepam 15 mg for the treatment of transient insomnia.
    Current medical research and opinion, 2004, Volume: 20, Issue:4

    Topics: Adult; Aged; Cognition; Double-Blind Method; Female; Humans; Male; Middle Aged; Polysomnography; Psy

2004
Zolpidem is not superior to temazepam with respect to rebound insomnia: a controlled study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2004, Volume: 14, Issue:4

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Double-Blind Method; Drug Tolerance; Female; Humans; Hypnoti

2004
[Signopam treatment of insomnia in patients with somatic pathology].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2004, Volume: 104, Issue:5

    Topics: Adolescent; Adult; Female; GABA Modulators; Humans; Male; Middle Aged; Sleep Initiation and Maintena

2004
Effects of 2-week treatment with temazepam and diphenhydramine in elderly insomniacs: a randomized, placebo-controlled trial.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:2

    Topics: Aged; Aged, 80 and over; Cross-Over Studies; Diphenhydramine; Dizziness; Dose-Response Relationship,

2008
Efficacy and side effects of lorazepam, oxazepam, and temazepam as sleeping aids in psychogeriatric inpatients.
    International pharmacopsychiatry, 1980, Volume: 15, Issue:2

    Topics: Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lorazepam;

1980
Double-blind evaluation of temazepam, flurazepam, and placebo in geriatric insomniacs.
    Clinical therapeutics, 1982, Volume: 4, Issue:5

    Topics: Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Flurazepam; Humans

1982
Treatment of insomnia with temazepam: double-blind, placebo-controlled evaluation.
    Clinical therapeutics, 1982, Volume: 4, Issue:5

    Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; F

1982
Model insomnia by methylphenidate and caffeine and use in the evaluation of temazepam.
    Psychopharmacology, 1982, Volume: 76, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Caffeine; Drug Evaluation; Electroencephalography; Electrooculography; H

1982
A comparison of chlormezanone and temazepam in sleep disturbance.
    Current medical research and opinion, 1982, Volume: 8, Issue:1

    Topics: Adult; Anti-Anxiety Agents; Chlormezanone; Female; Humans; Male; Sleep Initiation and Maintenance Di

1982
Clinical trials of hypnotics.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:2

    Topics: Anti-Anxiety Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Flurazepam; Half-Li

1983
A comparison of the hypnotic activity of loprazolam, temazepam and placebo in general practice.
    The Journal of international medical research, 1984, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Clinical Trials as Topic

1984
Psycho-social stress, insomnia and temazepam: a sleep laboratory evaluation in a "general practice" sample.
    Psychopharmacology, 1984, Volume: 83, Issue:1

    Topics: Adult; Anti-Anxiety Agents; Double-Blind Method; Electroencephalography; Female; Humans; Sleep Initi

1984
Temazepam's efficacy in patients with sleep onset insomnia.
    British journal of clinical pharmacology, 1984, Volume: 17, Issue:6

    Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; E

1984
Flurazepam and temazepam in the treatment of insomnia in a general hospital population.
    Pharmacopsychiatry, 1984, Volume: 17, Issue:4

    Topics: Adult; Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Flurazepam;

1984
A comparison of temazepam and flurazepam in terms of sleep quality and residual changes in performance.
    Neuropsychobiology, 1984, Volume: 11, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Attention; Cognition; Discrimination Learning; Female; Flicker Fusion; F

1984
Behavioral and pharmacological therapies for late-life insomnia: a randomized controlled trial.
    JAMA, 1999, Mar-17, Volume: 281, Issue:11

    Topics: Aged; Analysis of Variance; Anti-Anxiety Agents; Behavior Therapy; Chronic Disease; Cognitive Behavi

1999
A pharmacodynamic Markov mixed-effects model for the effect of temazepam on sleep.
    Clinical pharmacology and therapeutics, 2000, Volume: 68, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Cross-Over Studies; Female; Humans; Male; Markov Chain

2000
Are changes in beliefs and attitudes about sleep related to sleep improvements in the treatment of insomnia?
    Behaviour research and therapy, 2002, Volume: 40, Issue:7

    Topics: Anti-Anxiety Agents; Attitude; Cognitive Behavioral Therapy; Female; Follow-Up Studies; Humans; Inte

2002
Euhypnos Forte (temazepam) in insomniac patients: a clinical trial in general practice.
    The Journal of international medical research, 1979, Volume: 7, Issue:4

    Topics: Anti-Anxiety Agents; Capsules; Clinical Trials as Topic; Family Practice; Humans; Patient Dropouts;

1979
Euhypnos Forte (temazepam) for resistant insomnia: a clinical trial.
    The Journal of international medical research, 1979, Volume: 7, Issue:4

    Topics: Anti-Anxiety Agents; Anxiety; Capsules; Clinical Trials as Topic; Depression; Humans; Hypnotics and

1979
Hypnotic efficacy of temazepam: a long-term sleep laboratory evaluation.
    British journal of clinical pharmacology, 1979, Volume: 8, Issue:1

    Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Humans

1979
Double-blind evaluation of the safety and hypnotic efficacy of temazepam in insomniac outpatients.
    British journal of clinical pharmacology, 1979, Volume: 8, Issue:1

    Topics: Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Placebos;

1979
Double-blind evaluation of the efficacy and safety of temazepam in outpatients with insomnia.
    British journal of clinical pharmacology, 1979, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Human

1979
A double-blind comparison of the effects of temazepam and triazolam on residual, daytime performance in elderly insomniacs.
    International psychogeriatrics, 1992,Summer, Volume: 4, Issue:1

    Topics: Aged; Cognition; Double-Blind Method; Female; Geriatric Assessment; Humans; Male; Neuropsychological

1992
Next-day memory impairment with triazolam use.
    Lancet (London, England), 1991, Apr-06, Volume: 337, Issue:8745

    Topics: Activities of Daily Living; Adolescent; Adult; Amnesia, Retrograde; Capsules; Double-Blind Method; D

1991
A single-dose study of the pharmacodynamic effects of chlormethiazole, temazepam and placebo in elderly parkinsonian patients.
    Age and ageing, 1991, Volume: 20, Issue:6

    Topics: Aged; Benserazide; Carbidopa; Chlormethiazole; Double-Blind Method; Drug Therapy, Combination; Femal

1991
Rebound insomnia after only brief and intermittent use of rapidly eliminated benzodiazepines.
    Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:4

    Topics: Adult; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Random Allocation; Sleep Initiati

1991
A double-blind placebo-controlled trial of zopiclone 7.5 mg and temazepam 20 mg in insomnia.
    International clinical psychopharmacology, 1990, Volume: 5, Issue:3

    Topics: Adult; Azabicyclo Compounds; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Malaysia;

1990
Dose effects of temazepam in transient insomnia.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:8

    Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Electromyograp

1990
Temazepam withdrawal in elderly hospitalized patients: a double blind randomised trial comparing abrupt versus gradual withdrawal.
    Irish journal of medical science, 1989, Volume: 158, Issue:12

    Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Confusion; Double-Blind Method; Female; Humans; Inpati

1989
Zopiclone: a non-benzodiazepine hypnotic. Controlled comparison to temazepam in insomnia.
    The British journal of psychiatry : the journal of mental science, 1985, Volume: 146

    Topics: Adult; Aged; Anti-Anxiety Agents; Azabicyclo Compounds; Clinical Trials as Topic; Double-Blind Metho

1985
The effects of midazolam and temazepam on sleep and performance when administered in the middle of the night.
    Journal of clinical psychopharmacology, 1985, Volume: 5, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Female; Humans; Hypnotics and Sedatives; Male; Midazola

1985
Quazepam and temazepam: effects of short- and intermediate-term use and withdrawal.
    Clinical pharmacology and therapeutics, 1986, Volume: 39, Issue:3

    Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Drug Evaluation; Half-L

1986
A double-blind comparison of chlormethiazole and temazepam in elderly patients with sleep disturbances.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 329

    Topics: Aged; Anti-Anxiety Agents; Attention; Chlormethiazole; Clinical Trials as Topic; Double-Blind Method

1986
Dose effects of temazepam tablets on sleep.
    Drugs under experimental and clinical research, 1986, Volume: 12, Issue:8

    Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind

1986
Nocturnal myoclonus: treatment efficacy of clonazepam and temazepam.
    Sleep, 1986, Volume: 9, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Clonazepam; Female; Humans; Male; Middle Aged;

1986
Saccadic eye movements as a measure of residual effects: temazepam compared with other hypnotics.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 332

    Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Eye Movements; Female; Fl

1986
Aspects of driving after hypnotic therapy with particular reference to temazepam.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 332

    Topics: Anti-Anxiety Agents; Arousal; Attention; Automobile Driving; Female; Flunitrazepam; Humans; Male; Ps

1986
Insomnia in general practice: the role of temazepam and a comparison with zopiclone.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 332

    Topics: Anti-Anxiety Agents; Arousal; Azabicyclo Compounds; Clinical Trials as Topic; Double-Blind Method; H

1986
Psychopharmacological aspects of idiopathic and transient insomnia.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 332

    Topics: Adult; Anti-Anxiety Agents; Arousal; Attention; Clinical Trials as Topic; Double-Blind Method; Human

1986
Subjective effects during administration and on discontinuation of zopiclone and temazepam in normal subjects.
    Pharmacopsychiatry, 1987, Volume: 20, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Anxiety; Arousal; Azabicyclo Compounds; Female; Humans; Hypnotics and Se

1987
Evaluation of temazepam and diphenhydramine as hypnotics in a nursing-home population.
    Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:9

    Topics: Aged; Anti-Anxiety Agents; Diphenhydramine; Drug Evaluation; Female; Florida; Humans; Hypnotics and

1987
Efficacy without tolerance or rebound insomnia for midazolam and temazepam after use for one to three months.
    Journal of clinical pharmacology, 1987, Volume: 27, Issue:10

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Drug To

1987
Comparative amnestic effects of benzodiazepine hypnotic agents.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:4

    Topics: Adult; Amnesia; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Humans; Memory, Short-Term; M

1988
Altitude insomnia: studies during an expedition to the Himalayas.
    Sleep, 1988, Volume: 11, Issue:4

    Topics: Acetazolamide; Adult; Altitude Sickness; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Elec

1988
Hypnotics and actual driving performance.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 332

    Topics: Adult; Attention; Automobile Driving; Clinical Trials as Topic; Dose-Response Relationship, Drug; Do

1986

Other Studies

31 other studies available for temazepam and Chronic Insomnia

ArticleYear
Effect of withdrawal from long-term use of temazepam, zopiclone or zolpidem as hypnotic agents on cognition in older adults.
    European journal of clinical pharmacology, 2014, Volume: 70, Issue:3

    Topics: Aged; Azabicyclo Compounds; Cognition; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; M

2014
Effect of withdrawal from long-term use of temazepam, zopiclone or zolpidem as hypnotic agents on cognition in older adults.
    European journal of clinical pharmacology, 2014, Volume: 70, Issue:3

    Topics: Aged; Azabicyclo Compounds; Cognition; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; M

2014
Effect of withdrawal from long-term use of temazepam, zopiclone or zolpidem as hypnotic agents on cognition in older adults.
    European journal of clinical pharmacology, 2014, Volume: 70, Issue:3

    Topics: Aged; Azabicyclo Compounds; Cognition; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; M

2014
Effect of withdrawal from long-term use of temazepam, zopiclone or zolpidem as hypnotic agents on cognition in older adults.
    European journal of clinical pharmacology, 2014, Volume: 70, Issue:3

    Topics: Aged; Azabicyclo Compounds; Cognition; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; M

2014
Understanding women's sleep management: beyond medicalization-healthicization?
    Sociology of health & illness, 2003, Volume: 25, Issue:7

    Topics: Adult; Aged; Anti-Anxiety Agents; Family Practice; Female; Focus Groups; Humans; Hypnotics and Sedat

2003
Effects of temazepam 7.5 mg and temazepam 15 mg on sleep maintenance and sleep architecture in a model of transient insomnia.
    Current medical research and opinion, 2005, Volume: 21, Issue:2

    Topics: Adult; Aged; Anti-Anxiety Agents; Biomarkers; Double-Blind Method; Female; Humans; Male; Middle Aged

2005
Visual hallucination and temazepam: an unusual case.
    Journal of the American Geriatrics Society, 2006, Volume: 54, Issue:10

    Topics: Aged, 80 and over; Anti-Anxiety Agents; Hallucinations; Humans; Male; Sleep Initiation and Maintenan

2006
Euhypnos forte, high dose temazepam for resistant insomnia: post-marketing surveillance in 10,057 patients unresponsive to conventional hypnotic dosage.
    The Journal of international medical research, 1980, Volume: 8, Issue:6

    Topics: Anti-Anxiety Agents; Dose-Response Relationship, Drug; Humans; Sleep Initiation and Maintenance Diso

1980
Drugs & dosages: Restoril.
    Occupational health nursing, 1981, Volume: 29, Issue:9

    Topics: Anti-Anxiety Agents; Humans; Sleep Initiation and Maintenance Disorders; Temazepam

1981
Temazepam (Restoril) - another benzodiazepine for insomnia.
    The Medical letter on drugs and therapeutics, 1982, Feb-05, Volume: 24, Issue:602

    Topics: Anti-Anxiety Agents; Female; Humans; Male; Sleep Initiation and Maintenance Disorders; Temazepam

1982
[Effects of temazepam on experimental insomnia induced by methylphenidate in man].
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1982, Volume: 36, Issue:5

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Double-Blind Method; Habituation, Psychophysiologic; Humans;

1982
[Evening television and sleep. Polysomnographic, psychometric and psychopharmacologic studies in sleep disordered patients (II)].
    Die Medizinische Welt, 1983, Aug-12, Volume: 34, Issue:31-32

    Topics: Anti-Anxiety Agents; Dose-Response Relationship, Drug; Humans; Sleep Initiation and Maintenance Diso

1983
Withdrawal after substitution of a short-acting for a long-acting benzodiazepine.
    JAMA, 1983, Nov-25, Volume: 250, Issue:20

    Topics: Anti-Anxiety Agents; Anxiety; Chronic Disease; Delayed-Action Preparations; Diazepam; Flurazepam; Ha

1983
Insomnia and short-acting benzodiazepine hypnotics.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:2

    Topics: Benzodiazepines; Chemical Phenomena; Chemistry; Humans; Hypnotics and Sedatives; Kinetics; Sleep; Sl

1983
Long-term monitoring during sleep--a high-speed automatic processing system for human all-night sleep scoring and statistical data analysis.
    Electroencephalography and clinical neurophysiology. Supplement, 1982, Volume: 36

    Topics: Autoanalysis; Caffeine; Electroencephalography; Electromyography; Humans; Minicomputers; Monitoring,

1982
Temazepam 7.5 mg: effects on sleep in elderly insomniacs.
    European journal of clinical pharmacology, 1994, Volume: 46, Issue:3

    Topics: Aged; Anxiety; Chronic Disease; Electroencephalography; Electrooculography; Female; Humans; Male; Sl

1994
Management of insomnia in office-based practice. National prevalence and therapeutic patterns.
    Archives of family medicine, 1993, Volume: 2, Issue:11

    Topics: Adolescent; Adult; Aged; Data Collection; Female; Flurazepam; Humans; Male; Medicine; Middle Aged; P

1993
Prescribing practice and policy for hypnotics: a model of pharmacy audit.
    Age and ageing, 1996, Volume: 25, Issue:6

    Topics: Aged; Drug Utilization; England; Female; Geriatric Assessment; Humans; Hypnotics and Sedatives; Male

1996
Pharmacodynamics of temazepam in primary insomnia: assessment of the value of quantitative electroencephalography and saccadic eye movements in predicting improvement of sleep.
    Clinical pharmacology and therapeutics, 1997, Volume: 62, Issue:4

    Topics: Adult; Aged; Anti-Anxiety Agents; Electroencephalography; Female; Humans; Male; Middle Aged; Polysom

1997
Pilot evaluation of hypnotic medication during acute traumatic stress response.
    Journal of traumatic stress, 1998, Volume: 11, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Anti-Anxiety Agents; Arousal; Combined Modality Therapy; Crisis In

1998
Behaviour therapy for chronic insomnia.
    Prescrire international, 2001, Volume: 10, Issue:51

    Topics: Anti-Anxiety Agents; Behavior Therapy; Chronic Disease; Clinical Trials as Topic; Humans; Sleep Init

2001
Use of night-time benzodiazepines in an elderly inpatient population.
    Journal of clinical pharmacy and therapeutics, 2002, Volume: 27, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Anti-Anxiety Agents; Female; Geriatrics; Health Care Surveys; Hospit

2002
Euhypnos Forte (temazepam) for resistant insomnia: post-marketing surveillance, an interim report.
    The Journal of international medical research, 1979, Volume: 7, Issue:5

    Topics: Administration, Oral; Anti-Anxiety Agents; Capsules; Drug Evaluation; Humans; Sleep Initiation and M

1979
Hypnotics today.
    The Practitioner, 1979, Volume: 223, Issue:1336

    Topics: Aged; Anti-Anxiety Agents; Diazepam; Electroencephalography; Humans; Sleep; Sleep Initiation and Mai

1979
Clinical uses and advantages of low doses of benzodiazepine hypnotics.
    The Journal of clinical psychiatry, 1992, Volume: 53 Suppl

    Topics: Adult; Aged; Amnesia; Benzodiazepines; Dose-Response Relationship, Drug; Drug Administration Schedul

1992
Avoiding the blanket approach to insomnia. Targeted therapy for specific causes.
    Postgraduate medicine, 1991, Volume: 90, Issue:1

    Topics: Anti-Anxiety Agents; Benzodiazepines; Chronic Disease; Diagnosis, Differential; Estazolam; Flurazepa

1991
The beneficial and adverse effects of hypnotics.
    The Journal of clinical psychiatry, 1991, Volume: 52 Suppl

    Topics: Adolescent; Adult; Aged; Attitude to Health; Benzodiazepines; Data Collection; Drug Prescriptions; E

1991
Putting benzodiazepine hypnotics into proper therapeutic perspective.
    The Journal of the Medical Society of New Jersey, 1985, Volume: 82, Issue:3

    Topics: Anti-Anxiety Agents; Flurazepam; Humans; Sleep Initiation and Maintenance Disorders; Temazepam; Tria

1985
Agitation observed during treatment with newer hypnotic drugs.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:7

    Topics: Adult; Aged; Akathisia, Drug-Induced; Anger; Anti-Anxiety Agents; Female; Half-Life; Hostility; Huma

1985
Tranquilizers and sedative/hypnotics: appropriate use in the elderly.
    Geriatrics, 1986, Volume: 41, Issue:5

    Topics: Aged; Alprazolam; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Half-Life; Humans; Hypnotics and Se

1986
The use of benzodiazepines with particular reference to the elderly.
    British journal of hospital medicine, 1986, Volume: 35, Issue:5

    Topics: Aged; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Diazepam; Humans; Infusions, Parenteral; Kinet

1986
Pharmacokinetics of temazepam compared with other benzodiazepine hypnotics--some clinical consequences.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 332

    Topics: Anti-Anxiety Agents; Drug Administration Schedule; Humans; Kinetics; Sleep Initiation and Maintenanc

1986
Hypnotics and transient insomnia.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 332

    Topics: Altitude; Anti-Anxiety Agents; Arousal; Attention; Humans; Sleep Initiation and Maintenance Disorder

1986
Update on hypnotics for insomnia in clinical practice: I. Hypnotics.
    The Mount Sinai journal of medicine, New York, 1986, Volume: 53, Issue:2

    Topics: Adult; Humans; Hypnotics and Sedatives; Sleep Initiation and Maintenance Disorders; Temazepam; Triaz

1986