Page last updated: 2024-11-04

temazepam and Aging

temazepam has been researched along with Aging in 5 studies

Temazepam: A benzodiazepine that acts as a GAMMA-AMINOBUTYRIC ACID modulator and anti-anxiety agent.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Temazepam was more effective in impairing the performance of the young and old rat."5.27Aging: changes in a passive-avoidance response with brain levels of temazepam. ( Komiskey, HL; Mundinger, KL; Rahman, A, 1988)
"Temazepam clearance was lower in the elderly than in the young, but this difference was not statistically significant."2.67The influence of ciprofloxacin on the pharmacokinetics and pharmacodynamics of a single dose of temazepam in the young and elderly. ( Edwards, C; Herd, B; Kamali, F; Nicholson, E; Wynne, H, 1994)
"Temazepam was extensively protein bound, with a mean free fraction of 2."1.26Effect of age and gender on disposition of temazepam. ( Divoll, M; Greenblatt, DJ; Harmatz, JS; Shader, RI, 1981)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Divoll, M1
Greenblatt, DJ1
Harmatz, JS1
Shader, RI1
Kamali, F1
Herd, B1
Edwards, C1
Nicholson, E1
Wynne, H1
Ramesh, M1
Roberts, G1
Stone, BM1
Komiskey, HL1
Rahman, A1
Mundinger, KL1

Trials

1 trial available for temazepam and Aging

ArticleYear
The influence of ciprofloxacin on the pharmacokinetics and pharmacodynamics of a single dose of temazepam in the young and elderly.
    Journal of clinical pharmacy and therapeutics, 1994, Volume: 19, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Ciprofloxacin; Drug Evaluation; Female;

1994

Other Studies

4 other studies available for temazepam and Aging

ArticleYear
Effect of age and gender on disposition of temazepam.
    Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:10

    Topics: Adult; Aged; Aging; Anti-Anxiety Agents; Female; Half-Life; Humans; Kinetics; Male; Middle Aged; Pro

1981
Use of night-time benzodiazepines in an elderly inpatient population.
    Journal of clinical pharmacy and therapeutics, 2002, Volume: 27, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Anti-Anxiety Agents; Female; Geriatrics; Health Care Surveys; Hospit

2002
Diazepam and its hydroxylated metabolites: studies on sleep in healthy man.
    British journal of clinical pharmacology, 1979, Volume: 8, Issue:1

    Topics: Adult; Aging; Diazepam; Humans; Hydroxylation; Male; Middle Aged; Oxazepam; Sleep; Sleep, REM; Temaz

1979
Aging: changes in a passive-avoidance response with brain levels of temazepam.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3

    Topics: Aging; Animals; Anti-Anxiety Agents; Avoidance Learning; Behavior, Animal; Brain Chemistry; Dose-Res

1988