telmisartan has been researched along with Obesity in 57 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 13 (22.81) | 29.6817 |
2010's | 37 (64.91) | 24.3611 |
2020's | 7 (12.28) | 2.80 |
Authors | Studies |
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Frydrychowicz, A; Hübner, N; Kuerschner, L; Nickel, L; Othman, A; Raasch, W; Rawish, E; Saar, K; Schuster, F; Stölting, I | 1 |
He, J; Huang, C; Huang, H; Huang, Y; Li, R; Li, Y; Liu, Q; Tang, Q; Wu, T; Zhang, G; Zhang, J; Zhang, Z; Zhao, Y; Zhou, J | 1 |
Bazylevych, AY; Bochar, OM; Bochar, VT; Faynyk, AF; Kuzminov, YB; Sklyarova, HY | 1 |
Chen, W; Dang, C; Diao, D; Li, M; Wang, Y; Xie, X; Zhang, X | 1 |
Hövener, JB; Huber, G; Huber, L; Jurk, D; Matschl, U; Ogrodnik, M; Peschke, E; Raasch, W; Schwaninger, M; Stölting, I; Wenzel, J; Will, O | 1 |
Ameen, O; Motawea, SM; Naguib, YM; Rizk, MS; Samaka, RM | 1 |
Beckmann, L; Busch, H; Freitag, M; Freschi, ML; Fuchs, B; Galuska, CE; Hirose, M; Huber, G; Ibrahim, SM; Knobloch, JK; Künstner, A; Langan, EA; Matschl, U; Raasch, W; Stölting, I | 1 |
Banks, WA; Huber, G; Hübner, N; Raasch, W; Saar, K; Schuster, F; Stölting, I; Wing, EE | 1 |
Cheon, HG; Choi, HE; Jeon, EJ; Kim, DY; Lee, NH | 1 |
Alenina, N; Bader, M; Castro E Souza, LA; Dapper, C; Raasch, W; Schuster, F; Stölting, I; Vogt, F | 1 |
Bentzen, BH; Grunnet, M; Hansen, HH; Hyveled-Nielsen, L; Lassen, JB; Sundgreen, C | 1 |
Barykina, IN; Chumachok, EV; Ledyaeva, AA; Mazina, G; Nedogoda, SV; Salasyuk, AS; Tsoma, VV | 1 |
Sharma, K; Sweiss, N | 1 |
Kinoshita, S; Nakamoto, H; Nishida, E; Ryuzaki, M; Sone, M | 1 |
Barkhausen, J; Hübel, N; Mildner, M; Müller-Fielitz, H; Raasch, W; Vogt, FM | 1 |
Liu, Z; Lu, F; Peng, J; Tang, M; Wang, Z; Zhang, H; Zhang, W; Zhao, Y; Zhong, M | 1 |
Graus-Nunes, F; Mandarim-de-Lacerda, CA; Penna-de-Carvalho, A; Rabelo-Andrade, J; Souza-Mello, V | 1 |
Bochar, OM | 1 |
Bader, M; Barkhausen, J; Raasch, W; Santos, RA; Schuchard, J; Schuster, F; Stölting, I; Thorns, C; Vogt, FM; Winkler, M | 1 |
Bader, M; Barkhausen, J; Raasch, W; Schuchard, J; Stölting, I; Thorns, C; Vogt, FM; Winkler, M | 1 |
Choi, GJ; Kang, H; Kim, HM; Kim, J | 1 |
Alhusseini, NF; Ali, SI; Atteia, HH; Hasan, RA; Idris, RA | 1 |
Barini, A; Cardillo, C; Di Daniele, N; Mores, N; Schinzari, F; Tesauro, M; Veneziani, A | 1 |
Dahlöf, B; Ritz, E | 2 |
Sharma, AM | 2 |
Anderwald-Stadler, M; Bergmann, A; Clodi, M; Hülsmann, M; Luger, A; Morgenthaler, NG; Mörtl, D; Pacher, R; Pacini, G; Resl, M; Riedl, M; Stelzeneder, D; Struck, J; Tura, A | 1 |
Hirose, H; Itoh, H; Kawabe, H; Komiya, N; Saito, I | 1 |
Cao, T; Feng, X; He, H; Liu, D; Luo, Z; Ma, L; Ma, S; Tepel, M; Yan, Z; Yang, D; Zhu, Z | 1 |
Aguila, MB; Cardoso-de-Lemos, FS; de Carvalho, L; Gregório, BM; Mandarim-de-Lacerda, CA; Souza-Mello, V | 1 |
Awata, T; Ikebukuro, K; Inukai, K; Ito, D; Katayama, S; Kurihara, S; Ono, H; Sumita, T; Watanabe, M | 1 |
Davidai, G; Henry, R; Hsueh, W; Mudaliar, S | 1 |
Fernández-Fernández, FJ | 1 |
Clemenz, M; Foryst-Ludwig, A; Hartge, M; Hess, K; Kintscher, U; Marx, N; Sprang, C; Unger, T | 1 |
Aminuddin, A; Bukhari, A; Fujisaka, S; Ikutani, M; Kanatani, Y; Kobayashi, M; Nagai, Y; Senda, S; Suzuki, H; Tabuchi, Y; Takasaki, I; Takatsu, K; Tobe, K; Tsuneyama, K; Usui, I; Yamazaki, Y | 1 |
Alfieri, A; Buono, P; Franzese, A; Labruna, G; Licenziati, MR; Mancini, A; Musa, CV; Pasanisi, F; Sacchetti, L; Valerio, G | 1 |
Aguila, MB; da Silva Faria, T; Gregório, BM; Mandarim-de-Lacerda, CA; Relvas-Lucas, B; Souza-Mello, V | 1 |
Kochi, T; Kubota, M; Moriwaki, H; Ohno, T; Sakai, H; Shimizu, M; Tanaka, T; Tsurumi, H; Yasuda, Y | 1 |
Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Nakamura, T; Ogawa, H; Tokutomi, Y; Toyama, K; Yasuda, O | 1 |
Matsuura, K; Mori, Y; Tanaka, T; Utsunomiya, K; Yokoyama, J | 1 |
Sahebkar, A | 1 |
Hu, TJ; Huang, GZ; Tang, YH; Wang, BY; Zhang, B; Zhang, L; Zhang, XY; Zhong, Y | 1 |
Jöhren, O; Miesel, A; Müller-Fielitz, H; Raasch, W; Vogt, FM | 1 |
Heidbreder, M; Jöhren, O; Landolt, J; Müller-Fielitz, H; Raasch, W; Vogt, FM; Werth, S | 1 |
Adamczak, M; Chudek, J; Kubik, M; Wiecek, A | 1 |
Hirooka, Y; Kishi, T; Konno, S; Sunagawa, K | 1 |
Fukuda, D; Hirata, Y; Kurobe, H; Maeda, N; Masuzaki, H; Sakaue, H; Sata, M; Sato, H; Shimabukuro, M; Shimomura, I; Shiota, A; Soeki, T; Uematsu, E | 1 |
Ley, L; Schumacher, H | 1 |
Goto, SN; Mizuno, Y; Takagi, H; Umemoto, T; Yamamoto, H | 1 |
Engeli, S; Gorzelniak, K; Janke, J; Luft, FC; Sharma, AM | 1 |
Clasen, R; Clemenz, M; Foryst-Ludwig, A; Kintscher, U; Krikov, M; Schupp, M; Sprang, C; Thöne-Reineke, C; Unger, T | 1 |
Araki, K; Kakuma, T; Katsuragi, I; Masaki, T; Tanaka, K; Yoshimatsu, H | 1 |
Burnier, M; Dulloo, AG; Montani, JP; Perregaux, C; Zanchi, A | 1 |
Itoh, Y; Mori, Y; Tajima, N | 1 |
Davidson, J; Koval, S; Lacourcière, Y; Sharma, AM | 1 |
Janez, A; Jensterle, M; Kocjan, T; Meden-Vrtovec, H; Pfeifer, M; Prezelj, J; Vrtovec, B | 1 |
6 review(s) available for telmisartan and Obesity
Article | Year |
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Adiponectin effects on the kidney.
Topics: Adiponectin; Albuminuria; Amlodipine; AMP-Activated Protein Kinases; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Progression; Humans; Kidney; Kidney Diseases; Mice; Obesity; Oxidative Stress; Perindopril; Renal Insufficiency, Chronic; Telmisartan | 2014 |
Effects of telmisartan on fat distribution: a meta-analysis of randomized controlled trials.
Topics: Adipose Tissue; Benzimidazoles; Benzoates; Body Fat Distribution; Body Weight; Humans; Obesity; PPAR gamma; Randomized Controlled Trials as Topic; Telmisartan | 2016 |
The value of current interventions for obesity.
Topics: Adipogenesis; Angiotensin II Type 1 Receptor Blockers; Bariatric Surgery; Benzimidazoles; Benzoates; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Metabolic Syndrome; Obesity; Risk Factors; Telmisartan; Weight Loss | 2008 |
Telmisartan plus amlodipine single-pill combination for the management of hypertensive patients with a metabolic risk profile (added-risk patients).
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Clinical Trials as Topic; Diabetes Complications; Humans; Hypertension; MEDLINE; Obesity; Risk Factors; Telmisartan | 2013 |
Effects of telmisartan therapy on interleukin-6 and tumor necrosis factor-alpha levels: a meta-analysis of randomized controlled trials.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Confidence Intervals; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Hypertension, Renal; Imidazoles; Interleukin-6; Obesity; Prospective Studies; Publication Bias; Randomized Controlled Trials as Topic; Stents; Telmisartan; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan | 2013 |
The obese patient with diabetes mellitus: from research targets to treatment options.
Topics: Adipogenesis; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Obesity; Renin-Angiotensin System; Telmisartan; Weight Loss | 2006 |
11 trial(s) available for telmisartan and Obesity
Article | Year |
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Randomized trial of perindopril, enalapril, losartan and telmisartan in overweight or obese patients with hypertension.
Topics: Adult; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Enalapril; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Obesity; Overweight; Perindopril; Single-Blind Method; Telmisartan | 2013 |
Effectiveness of using long-acting angiotensin II type 1 receptor blocker in Japanese obese patients with metabolic syndrome on morning hypertension monitoring by using telemedicine system (FUJIYAMA study).
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cholesterol, LDL; Female; Humans; Hypertension; Japan; Male; Metabolic Syndrome; Middle Aged; Obesity; Prospective Studies; Telemedicine; Telmisartan; Tetrazoles | 2014 |
Prevention of metabolic disorders with telmisartan and indapamide in a Chinese population with high-normal blood pressure.
Topics: Aged; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; China; Double-Blind Method; Female; Humans; Hypertension; Indapamide; Male; Metabolic Diseases; Middle Aged; Obesity; Telmisartan; Treatment Outcome | 2015 |
Combined effect of appointment telmisartan and atorvastatin on hemodynamic indicators and the indicators of lipid profile in patients with arterial hypertension combined with obesity and steatohepatitis.
Topics: Acetamides; Adipokines; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Benzimidazoles; Benzoates; Breath Tests; Cholesterol, LDL; Drug Therapy, Combination; Fatty Liver; Female; Hemodynamics; Heptanoic Acids; Humans; Hypertension; Lipids; Male; Middle Aged; Obesity; Pyrroles; Telmisartan; Triglycerides | 2014 |
Interactions of glucose metabolism and chronic heart failure.
Topics: Benzimidazoles; Benzoates; Biomarkers; Biphenyl Compounds; Blood Glucose; Blood Pressure; Chronic Disease; Heart Failure; Humans; Lipid Metabolism; Middle Aged; Obesity; Telmisartan; Tetrazoles | 2009 |
Effects of telmisartan therapy on metabolic profiles and serum high molecular weight (HMW)-adiponectin level in Japanese male hypertensive subjects with abdominal obesity.
Topics: Adiponectin; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Female; Humans; Hypertension; Lipoproteins, LDL; Male; Metabolome; Obesity; Sex Factors; Telmisartan | 2009 |
Effects of telmisartan on insulin resistance in Japanese type 2 diabetic patients.
Topics: Adiponectin; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Cholesterol, HDL; Diabetes Mellitus, Type 2; Female; Homeostasis; Humans; Hypertension; Insulin Resistance; Japan; Lipoproteins, LDL; Male; Metabolic Syndrome; Middle Aged; Obesity; Oxidative Stress; PPAR gamma; Telmisartan; Tetrazoles | 2010 |
Telmisartan effects on insulin resistance in obese or overweight adults without diabetes or hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Female; Humans; Hypertension; Insulin Resistance; Male; Middle Aged; Obesity; Overweight; Telmisartan | 2010 |
Influence of telmisartan on insulin response after glucose loading in obese patients with hypertension: ARB trial of hypertension in obese patients with hyperinsulinemia assessed by oral glucose tolerance test (ATHLETE).
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Blood Pressure; Female; Glucose; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypertension; Insulin Resistance; Male; Obesity; Telmisartan; Tetrazoles; Valine; Valsartan | 2011 |
Effects of telmisartan on insulin resistance and visceral fat distribution in Chinese hypertensive patients with obesity.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; China; Female; Humans; Hypertension; Insulin Resistance; Intra-Abdominal Fat; Male; Middle Aged; Obesity; Telmisartan | 2011 |
Telmisartan/hydrochlorothiazide versus valsartan/hydrochlorothiazide in obese hypertensive patients with type 2 diabetes: the SMOOTH study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diabetes Mellitus, Type 2; Diastole; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Obesity; Placebos; Single-Blind Method; Systole; Telmisartan; Tetrazoles; Valine; Valsartan | 2007 |
40 other study(ies) available for telmisartan and Obesity
Article | Year |
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Telmisartan prevents development of obesity and normalizes hypothalamic lipid droplets.
Topics: Angiotensin II Type 1 Receptor Blockers; Animal Feed; Animals; Diet, High-Fat; Hypothalamus; Leptin; Lipid Droplets; Lipid Metabolism; Mice; Mice, Inbred C57BL; Obesity; Telmisartan; Weight Gain | 2020 |
Telmisartan attenuates obesity-induced insulin resistance via suppression of AMPK mediated ER stress.
Topics: 3T3-L1 Cells; AMP-Activated Protein Kinases; Angiotensin II Type 1 Receptor Blockers; Animals; Endoplasmic Reticulum Stress; Enzyme Activation; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Obesity; Telmisartan | 2020 |
The effect of therapy with olmesartan or telmisartan in patients with arterial hypertension combined with obesity.
Topics: Blood Pressure; Humans; Hypertension; Imidazoles; Obesity; Telmisartan; Tetrazoles | 2020 |
Obesity and metabolic syndrome related macrophage promotes PD-L1 expression in TNBC through IL6/JAK/STAT pathway and can be reversed by telmisartan.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; B7-H1 Antigen; Biomarkers, Tumor; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Metabolic Syndrome; Obesity; Rats; Rats, Wistar; Telmisartan; Triple Negative Breast Neoplasms | 2020 |
Telmisartan prevents high-fat diet-induced neurovascular impairments and reduces anxiety-like behavior.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anxiety; Diet, High-Fat; Disease Models, Animal; Male; Mice; Obesity; Telmisartan | 2021 |
Countering adipose tissue dysfunction could underlie the superiority of telmisartan in the treatment of obesity-related hypertension.
Topics: Adiposity; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Disease Models, Animal; Hypertension; Intra-Abdominal Fat; Kidney; Male; Obesity; Rats, Wistar; Telmisartan | 2021 |
Telmisartan induces a specific gut microbiota signature which may mediate its antiobesity effect.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Obesity Agents; Bacteria; Diet; Disease Models, Animal; Dysbiosis; Fecal Microbiota Transplantation; Feces; Gastrointestinal Microbiome; Mice; Obesity; Rats; Rats, Sprague-Dawley; Telmisartan; Weight Gain | 2021 |
Telmisartan prevents diet-induced obesity and preserves leptin transport across the blood-brain barrier in high-fat diet-fed mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Obesity Agents; Blood-Brain Barrier; Body Weight; Cell Line; Diet, High-Fat; Energy Metabolism; Humans; Leptin; Male; Mice; Mice, Inbred C57BL; Obesity; Telmisartan | 2018 |
Telmisartan induces browning of fully differentiated white adipocytes via M2 macrophage polarization.
Topics: Adipocytes, Brown; Adipocytes, White; Adipose Tissue, White; Angiotensin II Type 1 Receptor Blockers; Animals; Catecholamines; Cell Differentiation; Clodronic Acid; Culture Media, Conditioned; Humans; Insulin Resistance; Macrophage Activation; Macrophages; Male; Mice; Obesity; PPAR gamma; RAW 264.7 Cells; Receptors, Cytoplasmic and Nuclear; Telmisartan | 2019 |
The antiobese effect of AT1 receptor blockade is augmented in mice lacking Mas.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Obesity Agents; Body Weight; Diet, High-Fat; Mice, Knockout; Obesity; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Telmisartan | 2019 |
Anti-hypertensive treatment preserves appetite suppression while preventing cardiovascular adverse effects of tesofensine in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Obesity Agents; Antihypertensive Agents; Appetite; Appetite Depressants; Benzimidazoles; Benzoates; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cardiovascular Diseases; Dose-Response Relationship, Drug; Energy Intake; Feeding Behavior; Heart Rate; Male; Metoprolol; Obesity; Rats, Sprague-Dawley; Sympathomimetics; Telmisartan | 2013 |
Chronic blockade of angiotensin AT₁ receptors improves cardinal symptoms of metabolic syndrome in diet-induced obesity in rats.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Obesity Agents; Antihypertensive Agents; Behavior, Animal; Benzimidazoles; Benzoates; Diet, High-Fat; Dietary Sucrose; Drug Therapy, Combination; Energy Intake; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Insulin Resistance; Leptin; Male; Metabolic Syndrome; Obesity; Random Allocation; Rats; Rats, Inbred SHR; Telmisartan; Weight Gain | 2014 |
Enhanced pan-peroxisome proliferator-activated receptor gene and protein expression in adipose tissue of diet-induced obese mice treated with telmisartan.
Topics: Adipose Tissue; Animals; Benzimidazoles; Benzoates; Diet, High-Fat; Gene Expression; Insulin Resistance; Male; Mice; Mice, Obese; Obesity; Peroxisome Proliferator-Activated Receptors; Telmisartan | 2014 |
Lack of weight gain after angiotensin AT1 receptor blockade in diet-induced obesity is partly mediated by an angiotensin-(1-7)/Mas-dependent pathway.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Benzimidazoles; Benzoates; Diet; Energy Intake; Energy Metabolism; Insulin Resistance; Leptin; Male; Obesity; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; Signal Transduction; Telmisartan; Weight Gain; Weight Loss | 2015 |
The brain renin-angiotensin system plays a crucial role in regulating body weight in diet-induced obesity in rats.
Topics: Animals; Benzimidazoles; Benzoates; Body Weight; Brain; Diet; Male; Obesity; Rats; Rats, Transgenic; Renin-Angiotensin System; Telmisartan | 2016 |
Renoprotective effect of a combination of garlic and telmisartan against ischemia/reperfusion-induced kidney injury in obese rats.
Topics: Acute Kidney Injury; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Garlic; Kidney; Obesity; Rats; Reperfusion Injury; Telmisartan | 2016 |
Beneficial Effects of Apelin on Vascular Function in Patients With Central Obesity.
Topics: Acetylcholine; Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Annexins; Apelin; Benzimidazoles; Benzoates; Endothelium, Vascular; Female; Forearm; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Nitric Oxide; Nitroprusside; Obesity; omega-N-Methylarginine; Pyridines; Regional Blood Flow; Telmisartan; Vasodilation | 2017 |
A new dawn in cardiovascular protection: total cardiovascular risk: rigorous treatment of risk factors. Introduction.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Body Size; Cardiovascular Diseases; Humans; Life Style; Metabolic Syndrome; Obesity; Ramipril; Renin-Angiotensin System; Risk Assessment; Risk Factors; Telmisartan | 2008 |
Telmisartan prevents weight gain and obesity through activation of peroxisome proliferator-activated receptor-delta-dependent pathways.
Topics: Adipocytes; Adipose Tissue; Analysis of Variance; Animals; Benzimidazoles; Benzoates; Blotting, Western; Cell Differentiation; Cells, Cultured; Dietary Fats; Dose-Response Relationship, Drug; Drug Administration Schedule; Eating; Fluorescent Antibody Technique; Mice; Mice, Knockout; Obesity; PPAR delta; Signal Transduction; Telmisartan; Uncoupling Agents; Weight Gain | 2010 |
Comparative effects of telmisartan, sitagliptin and metformin alone or in combination on obesity, insulin resistance, and liver and pancreas remodelling in C57BL/6 mice fed on a very high-fat diet.
Topics: Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Dietary Fats; Dipeptidyl-Peptidase IV Inhibitors; Drug Evaluation, Preclinical; Drug Therapy, Combination; Energy Intake; Glucose Tolerance Test; Hypoglycemic Agents; Insulin Resistance; Liver; Male; Metabolic Syndrome; Metformin; Mice; Mice, Inbred C57BL; Obesity; Pancreas; Pyrazines; Sitagliptin Phosphate; Telmisartan; Triazoles | 2010 |
Telmisartan and obesity.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Humans; Obesity; PPAR delta; Risperidone; Schizophrenia; Telmisartan; Weight Loss | 2010 |
PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice.
Topics: Abdominal Fat; Animals; Anti-Inflammatory Agents; Antigens, Differentiation; Benzimidazoles; Benzoates; CD3 Complex; Chemokine CXCL12; Chemotaxis; Dietary Fats; Disease Models, Animal; Inflammation; Insulin Resistance; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR gamma; Rosiglitazone; T-Lymphocytes; Telmisartan; Thiazolidinediones; Time Factors | 2010 |
Telmisartan improves insulin resistance and modulates adipose tissue macrophage polarization in high-fat-fed mice.
Topics: Adipocytes; Adipose Tissue; Angiotensin II Type 1 Receptor Blockers; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Benzimidazoles; Benzoates; Body Weight; CD11c Antigen; Cell Adhesion Molecules; Cell Size; Dietary Fats; Epididymis; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation; Glucose; Insulin Resistance; Lectins, C-Type; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; Oligonucleotide Array Sequence Analysis; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; Telmisartan; Tumor Necrosis Factor-alpha | 2011 |
Four novel UCP3 gene variants associated with childhood obesity: effect on fatty acid oxidation and on prevention of triglyceride storage.
Topics: Age of Onset; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Child; Child, Preschool; Fatty Acids; Female; Genetic Variation; HEK293 Cells; Humans; Infant; Ion Channels; Italy; Lipid Metabolism; Male; Mitochondrial Proteins; Muscle, Skeletal; Mutation; Obesity; Oxidation-Reduction; Phosphorylation; Telmisartan; Triglycerides; Uncoupling Protein 3 | 2012 |
Pancreatic ultrastructural enhancement due to telmisartan plus sitagliptin treatment in diet-induced obese C57BL/6 mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Glucose; Dietary Fats; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Insulin; Islets of Langerhans; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Obesity; Pancreas; Pancreas, Exocrine; Pyrazines; Sitagliptin Phosphate; Telmisartan; Triazoles | 2011 |
Renin-angiotensin system inhibitors suppress azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db obese mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Azoxymethane; Benzimidazoles; Benzoates; Captopril; Colonic Neoplasms; Cyclooxygenase 2; Deoxyguanosine; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Obesity; Oxidative Stress; Plasminogen Activator Inhibitor 1; Precancerous Conditions; Renin-Angiotensin System; RNA, Messenger; Telmisartan; Tumor Necrosis Factor-alpha | 2011 |
Telmisartan protects against diabetic vascular complications in a mouse model of obesity and type 2 diabetes, partially through peroxisome proliferator activated receptor-γ-dependent activity.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anilides; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR gamma; Telmisartan | 2011 |
Metabolic improvement by telmisartan beyond angiotensin receptor blockade: role of adipokines.
Topics: Adipokines; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Humans; Insulin Resistance; Obesity; Resistin; Telmisartan; Tumor Necrosis Factor-alpha | 2011 |
Double blockade of angiotensin II (AT(1) )-receptors and ACE does not improve weight gain and glucose homeostasis better than single-drug treatments in obese rats.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Blood Glucose; Blood Pressure; Corticosterone; Drug Therapy, Combination; Feeding Behavior; Heart Rate; Leptin; Male; Obesity; Ramipril; Rats; Rats, Inbred SHR; Telmisartan; Weight Gain | 2012 |
Improved insulin sensitivity after long-term treatment with AT1 blockers is not associated with PPARγ target gene regulation.
Topics: Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Body Weight; Gene Expression Regulation; Glucose Tolerance Test; Hemodynamics; Hypothalamus; Insulin; Insulin Resistance; Male; Models, Biological; Obesity; PPAR gamma; Rats; Rats, Inbred SHR; Telmisartan; Tetrazoles | 2012 |
Telmisartan improves cardiometabolic profile in obese patients with arterial hypertension.
Topics: Adult; Aged; Benzimidazoles; Benzoates; Female; Humans; Hypertension; Insulin Resistance; Male; Metabolome; Middle Aged; Obesity; Telmisartan | 2012 |
Sympathoinhibitory effects of telmisartan through the reduction of oxidative stress in the rostral ventrolateral medulla of obesity-induced hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Blood Pressure; Brain Stem; Heart Rate; Hypertension; Male; Microinjections; Norepinephrine; Obesity; Oxidative Stress; Rats; Rats, Sprague-Dawley; Telmisartan; Thiobarbituric Acid Reactive Substances | 2012 |
Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice.
Topics: Adipocytes; Administration, Oral; AMP-Activated Protein Kinases; Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Benzimidazoles; Benzoates; Cell Line; Diabetes Mellitus; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Fatty Acid Transport Proteins; Glucose Transporter Type 4; Hypertrophy; Insulin; Islets of Langerhans; Male; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; NAD; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; PPAR gamma; RNA, Messenger; Signal Transduction; Sirtuin 1; Telmisartan; Time Factors; Trans-Activators; Transcription Factors | 2012 |
Angiotensin blockade prevents type 2 diabetes by formation of fat cells.
Topics: Adipocytes; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Cell Differentiation; Clinical Trials as Topic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Hypoglycemic Agents; Insulin Resistance; Obesity; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Telmisartan | 2002 |
Introduction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Hypertension; Hypoglycemic Agents; Obesity; Telmisartan | 2005 |
PPARgamma-activating angiotensin type-1 receptor blockers induce adiponectin.
Topics: 3T3-L1 Cells; Adipocytes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cycloheximide; Insulin Resistance; Irbesartan; Mice; Obesity; PPAR gamma; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Rats; Rats, Zucker; Receptor, Angiotensin, Type 2; Telmisartan; Tetrazoles | 2005 |
Telmisartan prevents obesity and increases the expression of uncoupling protein 1 in diet-induced obese mice.
Topics: Adiponectin; Adipose Tissue; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Body Weight; Carrier Proteins; Diet; Eating; Ion Channels; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Obesity; Oxygen Consumption; RNA, Messenger; Telmisartan; Triglycerides; Uncoupling Protein 1 | 2006 |
Telmisartan prevents the glitazone-induced weight gain without interfering with its insulin-sensitizing properties.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Drug Evaluation, Preclinical; Drug Interactions; Insulin; Insulin Resistance; Male; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; Telmisartan; Thiazolidinediones; Weight Gain | 2007 |
Angiotensin II receptor blockers downsize adipocytes in spontaneously type 2 diabetic rats with visceral fat obesity.
Topics: Adipocytes; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Glucose; Calcium Channel Blockers; Cell Size; Diabetes Mellitus, Type 2; Disease Models, Animal; Insulin; Intra-Abdominal Fat; Male; Obesity; PPAR gamma; Random Allocation; Rats; Rats, Long-Evans; Telmisartan; Tetrazoles; Valine; Valsartan | 2007 |
Decreased androgen levels and improved menstrual pattern after angiotensin II receptor antagonist telmisartan treatment in four hypertensive patients with polycystic ovary syndrome: case series.
Topics: Adult; Androgens; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Glucose; Blood Pressure; Body Mass Index; Fasting; Female; Humans; Hypertension; Menstruation; Obesity; Polycystic Ovary Syndrome; Telmisartan; Treatment Outcome | 2007 |