Page last updated: 2024-08-24

telmisartan and Inflammation

telmisartan has been researched along with Inflammation in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (17.65)29.6817
2010's34 (66.67)24.3611
2020's8 (15.69)2.80

Authors

AuthorsStudies
Abdel Hamid, AM; Abdel Monsef, AS; Abdo, W; Ahmeda, AF; Amer, ME; Antar, SA; El-Moselhy, LE; Farage, AE; Kamel, EM; Mahmoud, AM; Taha, RS1
Hattori, N; Matsuda, T; Nakatsuji, S; Nishiyama, N; Shimatsu, A; Yamada, A1
A Zezi, MY; Li, D; Wang, J; Zhou, X1
Asgharzadeh, F; Askarnia-Faal, MM; Avan, A; Daghiani, M; Hassanian, SM; Khazaei, M; Naimi, H; Nazari, SE; Sayyed-Hosseinian, SH; Vahedi, E1
Abdel-Daim, MM; Ahmed, OS; Hassanein, EHM; Mohamed, WR; Sayed, AM1
Cortés-Sanabria, L; Cueto-Manzano, AM; Cueto-Ramírez, AM; González-Plascencia, J; Martín-Del-Campo, F; Martínez-Martínez, P; Montañez-Fernández, JL; Ordaz-Medina, EJ; Ordaz-Medina, SM; Rojas-Campos, E; Trujillo-Hernández, B1
Daiber, A; Karbach, SH; Knopp, T; Kossmann, S; Molitor, M; Münzel, T; Schüler, R; Waisman, A; Wenzel, P; Wild, J1
Huang, C; Li, J; Li, ZQ; Ma, C; Wang, ZF1
Chen, L; Deng, M; Liang, Y; Ma, J; Wang, Y; Xu, J; Zhang, J; Zhang, L1
Abo-Youssef, AMH; El-Sayed, NS; Khallaf, WAI; Messiha, BAS1
Bae, SJ; Chang, J; Cho, DH; Cho, KW; Jo, I; Park, JH; Song, KH1
Bastow, B; Currier, JS; Deleage, C; Douek, DC; Estes, JD; Fichtenbaum, CJ; Kitch, DW; Klingman, KL; Lake, JE; Lederman, MM; Luque, AE; Magyar, C; McComsey, GA; Nelson, SD; Utay, NS; Yeh, E1
Gaikwad, AB; Malek, V; Sankrityayan, H; Sharma, N1
Choi, CS; Han, YI; Kang, KW; Mok, JS; Park, HD; Park, J; Park, JG; Park, TS1
Achenbach, S; Cicha, I; Garlichs, CD; Klinghammer, L; Lewczuk, P; Raaz-Schrauder, D; Urschel, K1
Li, LY; Luo, R; Sun, LT; Tian, FS; Xiong, HL; Zhao, ZQ; Zheng, XL1
Abdallah, DM; Al-Shorbagy, MY; Arab, HH; Nassar, NN1
Deng, Y; Guo, X; Liu, H; Shang, J; Yuan, X; Zhu, D1
Arya, DS; Bhatia, J; Dinda, AK; Gamad, N; Malik, S; Suchal, K1
Bai, J; Song, Z; Sun, X; Zhang, J; Zhang, L; Zhang, M; Zheng, H1
Gong, J; Gu, L; Guo, Z; Li, J; Li, N; Li, Y; Zhang, W; Zhu, W; Zuo, L1
Ramanathan, M; Saravanan, PB; Shanmuganathan, MV1
Abuohashish, HM; Ahmed, MM; Al-Rejaie, SS; Aleisa, AM; AlSharari, SD; Arrejaie, AS1
Araújo Júnior, RF; Araújo, AA; Fernandes, D; Guerra, GC; Lira, GA; Melo, MN; Silva, AL; Souto, KK1
Affram, K; Balarezo, MG; Saavedra, JM; Symes, AJ; Villapol, S1
Justin, A; Prathab Balaji, S; Ramanathan, M; Vijay Chand, C1
Cho, DH; Jo, I; Kim, SA; Park, JH; Park, JY; Seo, J; Song, KH1
Atawia, RT; El-Demerdash, E; Elsherbiny, DA; Esmat, A1
Breitbart, E; Ishai, E; Mendel, I; Shoham, A; Yacov, N1
Hulgan, T; Lake, JE; Le, CN; Milne, GL; Tseng, CH1
Inoue, H; Matsui, T; Nakamura, K; Takeuchi, M; Yamagishi, S1
Grzesiak, A; Kaschina, E; Kemnitz, UR; Krikov, M; Schrader, F; Sommerfeld, M; Unger, T1
Cheng, YX; Pan, Q; Yang, XH1
Gaikwad, AB; Mulay, SR; Tikoo, K1
Cadeddu, C; Deidda, M; Dessì, M; Madeddu, C; Mantovani, G; Massa, E; Mercuro, G; Piras, A1
Clemenz, M; Foryst-Ludwig, A; Hartge, M; Hess, K; Kintscher, U; Marx, N; Sprang, C; Unger, T1
Aizawa, Y; Gurusamy, N; Kodama, M; Ma, M; Rajavel, V; Sukumaran, V; Suzuki, K; Veeraveedu, PT; Watanabe, K; Yamaguchi, K1
Feng, W; Li, G; Tu, L; Wang, D; Xu, X; Yin, X1
Fujiwara, N; Kawagoe, Y; Koide, H; Nakamura, T; Sato, E; Ueda, Y; Yamada, S1
Akizawa, T; Aoshima, Y; Hirai, Y; Honda, H; Hosaka, N; Michihata, T1
Kobara, M; Nakata, T; Noda, K; Toba, H; Tojo, C; Wang, J1
Ganburged, G; Moriyama, K; Suda, N1
Arumugam, S; Harima, M; Kawachi, H; Lakshmanan, AP; Sari, FR; Soetikno, V; Suzuki, K; Watanabe, K1
Boor, P; Cohen, CD; Denecke, B; Eitner, F; Floege, J; Gan, L; Konieczny, A; Kunter, U; Neusser, MA; Ostendorf, T; Scholl, T; van Roeyen, CR; Villa, L1
Fujiwara, M; Irie, K; Iwasaki, K; Katsurabayashi, S; Kubota, K; Mishima, K; Nishimura, R; Onimura, R; Shindo, T; Takasaki, K; Uchida, K; Uchida, N1
Inoue, M; Ishida, S; Izumi-Nagai, K; Kubota, Y; Nagai, N; Noda, K; Oike, Y; Ozawa, Y; Suda, T; Tsubota, K; Urano, T1
Böhm, M; Legner, D; Lenz, M; Link, A; Nickenig, G1
Hoshide, S; Ishikawa, J; Ishikawa, S; Kanemaru, Y; Kario, K; Noguchi, C; Shimada, K; Tada, M; Takanori, H; Tukui, D; Yano, A; Yano, Y1
Chu, K; Jung, KH; Kim, EH; Kim, JM; Kim, M; Kim, SJ; Lee, ST; Park, DK; Roh, JK; Sinn, DI; Song, EC1
Bea, F; Blessing, E; Gräfe, J; Isermann, B; Katus, HA; Kinscherf, R; Kranzhöfer, R; Kreuzer, J; Marx, N; Preusch, M; Rosenfeld, ME; Weber, CM1
Fujitani, Y; Hirose, T; Ikeda, F; Kawamori, R; Mita, T; Nakayama, S; Shimizu, T; Uchino, H; Watada, H1

Reviews

1 review(s) available for telmisartan and Inflammation

ArticleYear
The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view.
    Life sciences, 2022, Nov-01, Volume: 308

    Topics: Acetylcysteine; Cadmium; Cytochalasin D; Cytokines; Humans; Inflammation; Kidney Diseases; NF-kappa B; Polysaccharides; Sildenafil Citrate; Telmisartan

2022

Trials

7 trial(s) available for telmisartan and Inflammation

ArticleYear
Randomized, double-blinded, controlled clinical trial of the effect of captopril, telmisartan and their combination on systemic inflammation of patients on hemodialysis.
    Scientific reports, 2022, 10-20, Volume: 12, Issue:1

    Topics: Biomarkers; C-Reactive Protein; Captopril; Double-Blind Method; Humans; Inflammation; Interleukin-6; Renal Dialysis; Telmisartan; Tumor Necrosis Factor-alpha

2022
Telmisartan Therapy Does Not Improve Lymph Node or Adipose Tissue Fibrosis More Than Continued Antiretroviral Therapy Alone.
    The Journal of infectious diseases, 2018, 05-05, Volume: 217, Issue:11

    Topics: Adipose Tissue; Adult; Antihypertensive Agents; Antiretroviral Therapy, Highly Active; Female; Fibrosis; HIV Infections; Humans; Inflammation; Lymph Nodes; Male; Middle Aged; PPAR gamma; Telmisartan

2018
Urine Eicosanoids in the Metabolic Abnormalities, Telmisartan, and HIV Infection (MATH) Trial.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Adipose Tissue; Adult; Angiotensin II Type 1 Receptor Blockers; Anthropometry; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzimidazoles; Benzoates; Body Fat Distribution; Eicosanoids; Female; HIV Infections; Humans; Inflammation; Lipodystrophy; Male; Middle Aged; Oxidative Stress; Pilot Projects; Prospective Studies; Sex Factors; Telmisartan; Waist-Hip Ratio

2017
Protective effects of the angiotensin II receptor blocker telmisartan on epirubicin-induced inflammation, oxidative stress, and early ventricular impairment.
    American heart journal, 2010, Volume: 160, Issue:3

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antibiotics, Antineoplastic; Benzimidazoles; Benzoates; Cytokines; Echocardiography, Doppler; Epirubicin; Female; Heart; Humans; Inflammation; Inflammation Mediators; Male; Middle Aged; Myocardial Contraction; Oxidative Stress; Renin-Angiotensin System; Systole; Telmisartan; Ventricular Dysfunction, Left

2010
Changes in urinary albumin excretion, inflammatory and oxidative stress markers in ADPKD patients with hypertension.
    The American journal of the medical sciences, 2012, Volume: 343, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Biomarkers; Creatinine; Deoxyguanosine; Enalapril; Female; HMGB1 Protein; Humans; Hypertension; Inflammation; Interleukin-6; Male; Middle Aged; Oxidative Stress; Polycystic Kidney, Autosomal Dominant; Telmisartan

2012
Olmesartan medoxomil is associated with decreased plasma AGEs, pentosidine, and N-(epsilon)-carboxymethyl-lysine levels in hemodialysis patients.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Arginine; Benzimidazoles; Benzoates; Blood Pressure; Female; Glycation End Products, Advanced; Humans; Hypertension, Renal; Imidazoles; Inflammation; Kidney Failure, Chronic; Lysine; Male; Olmesartan Medoxomil; Oxidative Stress; Pilot Projects; Prospective Studies; Renal Dialysis; Telmisartan; Tetrazoles; Treatment Outcome

2012
The differential effects of angiotensin II type 1 receptor blockers on microalbuminuria in relation to low-grade inflammation in metabolic hypertensive patients.
    American journal of hypertension, 2007, Volume: 20, Issue:5

    Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; C-Reactive Protein; Female; Humans; Hypertension; Inflammation; Male; Metabolic Syndrome; PPAR gamma; Telmisartan; Treatment Outcome

2007

Other Studies

43 other study(ies) available for telmisartan and Inflammation

ArticleYear
Telmisartan attenuates diabetic nephropathy by mitigating oxidative stress and inflammation, and upregulating Nrf2/HO-1 signaling in diabetic rats.
    Life sciences, 2022, Feb-15, Volume: 291

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Heme Oxygenase (Decyclizing); Inflammation; Kidney; Male; Molecular Docking Simulation; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Telmisartan

2022
Telmisartan is the most effective ARB to increase adiponectin via PPARα in adipocytes.
    Journal of molecular endocrinology, 2022, 05-10, Volume: 69, Issue:1

    Topics: Adipocytes; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzoates; Humans; Inflammation; Irbesartan; Leptin; PPAR alpha; PPAR gamma; RNA, Messenger; Telmisartan

2022
Telmisartan ameliorates LPS-induced pneumonia in rats through regulation of the PPARγ/NF-κB pathway.
    Microbiology and immunology, 2022, Volume: 66, Issue:7

    Topics: Acute Lung Injury; Animals; Cytokines; Inflammation; Lipopolysaccharides; Male; NF-kappa B; Pneumonia; PPAR gamma; Rats; Rats, Sprague-Dawley; Telmisartan

2022
Effect of angiotensin II pathway inhibitors on post-surgical adhesion band formation: a potential repurposing of old drugs.
    Injury, 2022, Volume: 53, Issue:11

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Drug Repositioning; Enalapril; Eosine Yellowish-(YS); Fibrosis; Hematoxylin; Inflammation; Pharmaceutical Preparations; Rats; Rats, Wistar; Sulfhydryl Compounds; Superoxide Dismutase; Telmisartan; Tissue Adhesions

2022
Telmisartan Lowers Elevated Blood Pressure in Psoriatic Mice without Attenuating Vascular Dysfunction and Inflammation.
    International journal of molecular sciences, 2019, Aug-30, Volume: 20, Issue:17

    Topics: Animals; Blood Pressure; Endothelium, Vascular; Inflammation; Mice; Oxidative Stress; Psoriasis; Skin; Telmisartan

2019
Telmisartan ameliorates Aβ oligomer-induced inflammation via PPARγ/PTEN pathway in BV2 microglial cells.
    Biochemical pharmacology, 2020, Volume: 171

    Topics: Amyloid beta-Protein Precursor; Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Cell Line; Cytokines; Humans; Inflammation; Inflammation Mediators; Mice; Microglia; PPAR gamma; PTEN Phosphohydrolase; Signal Transduction; Telmisartan

2020
Telmisartan mitigates lipopolysaccharide (LPS)-induced production of mucin 5AC (MUC5AC) through increasing suppressor of cytokine signaling 1 (SOCS1).
    Bioengineered, 2021, Volume: 12, Issue:1

    Topics: Acute Lung Injury; Cell Line; Humans; Inflammation; Lipopolysaccharides; Mucin 5AC; Protective Agents; Signal Transduction; Suppressor of Cytokine Signaling 1 Protein; Telmisartan

2021
Protective effects of telmisartan and tempol on lipopolysaccharide-induced cognitive impairment, neuroinflammation, and amyloidogenesis: possible role of brain-derived neurotrophic factor.
    Canadian journal of physiology and pharmacology, 2017, Volume: 95, Issue:7

    Topics: Amyloid; Animals; Benzimidazoles; Benzoates; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Cyclic N-Oxides; Cytoprotection; Inflammation; Lipopolysaccharides; Male; Mice; Oxidative Stress; Spin Labels; Telmisartan

2017
Telmisartan mitigates hyperglycemia-induced vascular inflammation by increasing GSK3β-Ser
    Biochemical and biophysical research communications, 2017, 09-30, Volume: 491, Issue:4

    Topics: Animals; Aorta; Benzimidazoles; Benzoates; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Glycogen Synthase Kinase 3 beta; Hyperglycemia; Inflammation; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Phosphoserine; Structure-Activity Relationship; Telmisartan; Vasculitis

2017
Concurrent neprilysin inhibition and renin-angiotensin system modulations prevented diabetic nephropathy.
    Life sciences, 2019, Mar-15, Volume: 221

    Topics: Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diminazene; Fibrosis; Inflammation; Kidney; Male; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System; Streptozocin; Telmisartan; Thiorphan

2019
Connectivity mapping of angiotensin-PPAR interactions involved in the amelioration of non-alcoholic steatohepatitis by Telmisartan.
    Scientific reports, 2019, 03-08, Volume: 9, Issue:1

    Topics: Angiotensins; Animals; Cell Line, Tumor; Inflammation; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Peroxisome Proliferator-Activated Receptors; Telmisartan; Transcriptome

2019
Impact of telmisartan on the inflammatory state in patients with coronary atherosclerosis--influence on IP-10, TNF-α and MCP-1.
    Cytokine, 2013, Volume: 62, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Atherosclerosis; Benzimidazoles; Benzoates; Blood Pressure; Chemokine CCL2; Chemokine CXCL10; Coronary Artery Disease; Female; Humans; Hypertension; Inflammation; Interleukin-6; Male; Middle Aged; Telmisartan; Tumor Necrosis Factor-alpha

2013
Angiotensin II receptor blocker telmisartan prevents new-onset diabetes in pre-diabetes OLETF rats on a high-fat diet: evidence of anti-diabetes action.
    Canadian journal of diabetes, 2013, Volume: 37, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Glucose; Blood Pressure; Body Weight; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Gene Expression; Hypoglycemic Agents; Inflammation; Insulin Resistance; Male; Metformin; Pioglitazone; Rats; Rats, Inbred OLETF; Telmisartan; Thiazolidinediones

2013
Telmisartan attenuates colon inflammation, oxidative perturbations and apoptosis in a rat model of experimental inflammatory bowel disease.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Angiotensin II Type 2 Receptor Blockers; Animals; Antioxidants; Apoptosis; Benzimidazoles; Benzoates; Colitis; Colon; Disease Models, Animal; Glutathione; Glutathione Peroxidase; Immunohistochemistry; Inflammation; Inflammatory Bowel Diseases; Lipid Peroxidation; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger; Superoxide Dismutase; Telmisartan; Trinitrobenzenesulfonic Acid

2014
Chronic intermittent hypoxia-induced neuronal apoptosis in the hippocampus is attenuated by telmisartan through suppression of iNOS/NO and inhibition of lipid peroxidation and inflammatory responses.
    Brain research, 2015, Jan-30, Volume: 1596

    Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzimidazoles; Benzoates; C-Reactive Protein; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Hippocampus; Hypoxia; In Situ Nick-End Labeling; Inflammation; Interleukin-6; Leukocyte Common Antigens; Lipid Peroxidation; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Telmisartan

2015
Telmisartan ameliorates cisplatin-induced nephrotoxicity by inhibiting MAPK mediated inflammation and apoptosis.
    European journal of pharmacology, 2015, Feb-05, Volume: 748

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzimidazoles; Benzoates; Cisplatin; Cytoprotection; Enzyme Activation; Inflammation; Kidney; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Oxidative Stress; Rats; Rats, Wistar; Telmisartan; Tumor Necrosis Factor-alpha

2015
[Effects of telmisartan on inflammation and fibrosis after acute myocardial infarction in rats].
    Zhonghua yi xue za zhi, 2014, Sep-09, Volume: 94, Issue:33

    Topics: Animals; Anterior Wall Myocardial Infarction; Benzimidazoles; Benzoates; C-Reactive Protein; Chemokine CCL2; Drugs, Chinese Herbal; Fibrosis; Inflammation; Interleukin-1beta; Interleukin-6; Matrix Metalloproteinase 9; Myocardial Infarction; Myocardium; NF-kappa B; Rats; Telmisartan; Tumor Necrosis Factor-alpha

2014
Telmisartan attenuates the inflamed mesenteric adipose tissue in spontaneous colitis by mechanisms involving regulation of neurotensin/microRNA-155 pathway.
    Biochemical pharmacology, 2015, Feb-15, Volume: 93, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Colitis; Inflammation; Intra-Abdominal Fat; Male; Mice; Mice, Inbred C3H; Mice, Knockout; MicroRNAs; Neurotensin; Telmisartan

2015
Telmisartan attenuated LPS-induced neuroinflammation in human IMR-32 neuronal cell line via SARM in AT1R independent mechanism.
    Life sciences, 2015, Jun-01, Volume: 130

    Topics: Angiotensin II Type 1 Receptor Blockers; Anilides; Armadillo Domain Proteins; Benzimidazoles; Benzoates; Cell Line; Cytokines; Cytoskeletal Proteins; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Inflammation Mediators; Lipopolysaccharides; Neurons; Neuroprotective Agents; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Telmisartan; Toll-Like Receptor 4

2015
Telmisartan inhibits hyperalgesia and inflammatory progression in a diabetic neuropathic pain model of Wistar rats.
    Neurosciences (Riyadh, Saudi Arabia), 2015, Volume: 20, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Cytokines; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hyperalgesia; Inflammation; Male; Motor Activity; Pain Measurement; Physical Stimulation; Rats; Rats, Wistar; Sciatic Nerve; Telmisartan

2015
Telmisartan decreases inflammation by modulating TNF-α, IL-10, and RANK/RANKL in a rat model of ulcerative colitis.
    Pharmacological reports : PR, 2015, Volume: 67, Issue:3

    Topics: Animals; Benzimidazoles; Benzoates; Colitis, Ulcerative; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Interleukin-10; RANK Ligand; Rats; Rats, Wistar; Receptor Activator of Nuclear Factor-kappa B; Telmisartan; Tumor Necrosis Factor-alpha

2015
Neurorestoration after traumatic brain injury through angiotensin II receptor blockage.
    Brain : a journal of neurology, 2015, Volume: 138, Issue:Pt 11

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzamides; Benzimidazoles; Benzoates; Biphenyl Compounds; Brain Injuries; Cerebrovascular Circulation; Gliosis; Inflammation; Mice; Mice, Knockout; Microglia; Neurons; Neuroprotective Agents; PPAR gamma; Pyridines; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan; Tetrazoles

2015
Telmisartan mediates anti-inflammatory and not cognitive function through PPAR-γ agonism via SARM and MyD88 signaling.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 137

    Topics: Animals; Anti-Inflammatory Agents; Armadillo Domain Proteins; Benzimidazoles; Benzoates; Cognition; Cytoskeletal Proteins; Inflammation; Male; Maze Learning; Myeloid Differentiation Factor 88; PPAR gamma; Rats; Rats, Sprague-Dawley; Signal Transduction; Telmisartan

2015
Telmisartan attenuates hyperglycemia-exacerbated VCAM-1 expression and monocytes adhesion in TNFα-stimulated endothelial cells by inhibiting IKKβ expression.
    Vascular pharmacology, 2016, Volume: 78

    Topics: Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Benzimidazoles; Benzoates; Cattle; Cell Adhesion; Diabetes Mellitus; Endothelial Cells; Humans; Hyperglycemia; I-kappa B Kinase; Inflammation; Monocytes; PPAR gamma; Rosiglitazone; Telmisartan; Thiazolidinediones; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2016
Telmisartan ameliorates carbon tetrachloride-induced acute hepatotoxicity in rats.
    Environmental toxicology, 2017, Volume: 32, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Benzoates; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Inflammation; Inflammation Mediators; Liver Function Tests; Male; Oxidative Stress; Rats; Rats, Wistar; Telmisartan

2017
Treatment with Oxidized Phospholipids Directly Inhibits Nonalcoholic Steatohepatitis and Liver Fibrosis Without Affecting Steatosis.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:9

    Topics: Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Glucose; Blotting, Western; Cell Movement; Cytokines; Dendritic Cells; Diabetes Mellitus, Experimental; Diet, High-Fat; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glycerophosphates; Glycerylphosphorylcholine; Hepatic Stellate Cells; Humans; Inflammation; Kupffer Cells; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Monocytes; Non-alcoholic Fatty Liver Disease; Phospholipids; Pyridinium Compounds; Real-Time Polymerase Chain Reaction; Telmisartan; Toll-Like Receptor 2; Toll-Like Receptor 4; Triglycerides

2016
Telmisartan inhibits advanced glycation end products (AGEs)-elicited endothelial cell injury by suppressing AGE receptor (RAGE) expression via peroxisome proliferator-activated receptor-gammaactivation.
    Protein and peptide letters, 2008, Volume: 15, Issue:8

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Cattle; Down-Regulation; Endothelial Cells; Glycation End Products, Advanced; Humans; Inflammation; PPAR gamma; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Telmisartan

2008
Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation.
    Journal of hypertension, 2008, Volume: 26, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Benzimidazoles; Benzoates; Blood Pressure; Cathepsin D; Disease Models, Animal; Dose-Response Relationship, Drug; Hydralazine; Inflammation; Male; Matrix Metalloproteinase 3; NF-kappa B; Protein Denaturation; Rats; Rats, Inbred BN; Telmisartan; Tumor Necrosis Factor-alpha

2008
Angiotensin II stimulates MCP-1 production in rat glomerular endothelial cells via NAD(P)H oxidase-dependent nuclear factor-kappa B signaling.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2009, Volume: 42, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blotting, Western; Chemokine CCL2; Endothelial Cells; Enzyme Inhibitors; Inflammation; Kidney Glomerulus; NADPH Oxidases; NF-kappa B; Onium Compounds; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Telmisartan

2009
Combination of aspirin with telmisartan suppresses the augmented TGFbeta/smad signaling during the development of streptozotocin-induced type I diabetic nephropathy.
    Chemico-biological interactions, 2010, Apr-29, Volume: 185, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzimidazoles; Benzoates; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gene Expression Regulation; Inflammation; Male; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Streptozocin; Telmisartan; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2010
PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice.
    Cardiovascular diabetology, 2010, Oct-18, Volume: 9

    Topics: Abdominal Fat; Animals; Anti-Inflammatory Agents; Antigens, Differentiation; Benzimidazoles; Benzoates; CD3 Complex; Chemokine CXCL12; Chemotaxis; Dietary Fats; Disease Models, Animal; Inflammation; Insulin Resistance; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR gamma; Rosiglitazone; T-Lymphocytes; Telmisartan; Thiazolidinediones; Time Factors

2010
Telmisartan ameliorates experimental autoimmune myocarditis associated with inhibition of inflammation and oxidative stress.
    European journal of pharmacology, 2011, Feb-10, Volume: 652, Issue:1-3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Autoimmune Diseases; Benzimidazoles; Benzoates; Blotting, Western; Cytokines; Disease Models, Animal; Endomyocardial Fibrosis; Enzyme-Linked Immunosorbent Assay; Inflammation; Male; Myocarditis; Oxidative Stress; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; Telmisartan

2011
Telmisartan protects against insulin resistance by attenuating inflammatory response in rats.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2011, Volume: 31, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; C-Reactive Protein; Chemokine CCL2; Cytokines; Dietary Fats; I-kappa B Proteins; Inflammation; Insulin Resistance; Male; NF-KappaB Inhibitor alpha; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; RNA, Messenger; Telmisartan

2011
Telmisartan inhibits vascular dysfunction and inflammation via activation of peroxisome proliferator-activated receptor-γ in subtotal nephrectomized rat.
    European journal of pharmacology, 2012, Jun-15, Volume: 685, Issue:1-3

    Topics: Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Aorta; Benzimidazoles; Benzoates; Blood Urea Nitrogen; Disease Models, Animal; Inflammation; Kidney Failure, Chronic; Losartan; Male; Malondialdehyde; Nephrectomy; PPAR gamma; Rats; Rats, Wistar; Telmisartan; Vasodilation

2012
Effect of angiotensin II receptor blocker on experimental periodontitis in a mouse model of Marfan syndrome.
    Infection and immunity, 2013, Volume: 81, Issue:1

    Topics: Alveolar Bone Loss; Angiotensin Receptor Antagonists; Animals; Bacteroidaceae Infections; Benzimidazoles; Benzoates; Bone Resorption; Disease Models, Animal; Inflammation; Interleukin-17; Male; Marfan Syndrome; Mice; Osteoclasts; Periodontitis; Porphyromonas gingivalis; Telmisartan; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2013
Curcumin alleviates oxidative stress, inflammation, and renal fibrosis in remnant kidney through the Nrf2-keap1 pathway.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:9

    Topics: Animals; Benzimidazoles; Benzoates; Blood Pressure; Blood Urea Nitrogen; Creatinine; Curcumin; Cyclooxygenase 2; Fibronectins; Fibrosis; Heme Oxygenase (Decyclizing); Inflammation; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Kidney; Kidney Diseases; Male; Nephrectomy; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Signal Transduction; Telmisartan; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2013
Late angiotensin II receptor blockade in progressive rat mesangioproliferative glomerulonephritis: new insights into mechanisms.
    The Journal of pathology, 2013, Volume: 229, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Blood Pressure; Cell Dedifferentiation; Cell Line; Chemokine CCL20; Cytoprotection; Disease Models, Animal; Fibrosis; Gene Expression Profiling; Gene Expression Regulation; Glomerular Mesangium; Glomerulonephritis, Membranoproliferative; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Inflammation; Isoantibodies; Macrophages; Male; Mice; Nephrectomy; Podocytes; Proteinuria; Rats; Rats, Wistar; Receptors, CCR6; Receptors, Platelet-Derived Growth Factor; RNA Interference; RNA, Messenger; Telmisartan; Time Factors; Transfection

2013
Ameliorative effects of telmisartan on the inflammatory response and impaired spatial memory in a rat model of Alzheimer's disease incorporating additional cerebrovascular disease factors.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:12

    Topics: Alzheimer Disease; Amyloid; Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Anti-Inflammatory Agents; Benzimidazoles; Benzoates; Brain Ischemia; Cerebrovascular Disorders; Cerebrum; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Inflammation; Male; Maze Learning; Memory; Memory Disorders; PPAR gamma; Rats; Rats, Wistar; Telmisartan; Tumor Necrosis Factor-alpha

2012
Angiotensin II type 1 receptor-mediated inflammation is required for choroidal neovascularization.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:10

    Topics: Angiogenesis Inducing Agents; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Cell Line; Cell Movement; Choroidal Neovascularization; Endothelial Cells; Humans; Inflammation; Inflammation Mediators; Macrophages; Mice; Mice, Inbred C57BL; PPAR gamma; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Telmisartan; Tissue Distribution

2006
Telmisartan inhibits beta2-integrin MAC-1 expression in human T-lymphocytes.
    Journal of hypertension, 2006, Volume: 24, Issue:9

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; C-Reactive Protein; CD18 Antigens; Cell Adhesion; Double-Blind Method; Female; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Lymphocytes; Macrophage-1 Antigen; Male; Middle Aged; Prospective Studies; Renin-Angiotensin System; T-Lymphocytes; Telmisartan

2006
Blockade of AT1 receptor reduces apoptosis, inflammation, and oxidative stress in normotensive rats with intracerebral hemorrhage.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzimidazoles; Benzoates; Cerebral Hemorrhage; Inflammation; Neuroprotective Agents; Nitric Oxide Synthase Type III; Oxidative Stress; PPAR gamma; Rats; Telmisartan; Up-Regulation

2007
Anti-atherosclerotic properties of telmisartan in advanced atherosclerotic lesions in apolipoprotein E deficient mice.
    Atherosclerosis, 2008, Volume: 199, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Atherosclerosis; Benzimidazoles; Benzoates; Early Growth Response Protein 1; Inflammation; Macrophages; Male; Mice; Mice, Transgenic; NF-kappa B; Nitric Oxide Synthase Type II; PPAR gamma; Renin-Angiotensin System; Telmisartan

2008
Comparison of effects of olmesartan and telmisartan on blood pressure and metabolic parameters in Japanese early-stage type-2 diabetics with hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:1

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Imidazoles; Inflammation; Japan; Male; Metabolic Syndrome; Middle Aged; Telmisartan; Tetrazoles

2008