telmisartan has been researched along with Cirrhosis in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (19.57) | 29.6817 |
| 2010's | 32 (69.57) | 24.3611 |
| 2020's | 5 (10.87) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, Y; Chen, X; Chu, C; Delic, D; Frankenreiter, S; Gaballa, MMS; Hasan, AA; Hocher, B; Klein, T; Krämer, BK; Luo, T; Stadermann, K; Xiong, Y; Xue, Y; Yin, L; Zeng, S | 1 |
| Asgharzadeh, F; Askarnia-Faal, MM; Avan, A; Daghiani, M; Hassanian, SM; Khazaei, M; Naimi, H; Nazari, SE; Sayyed-Hosseinian, SH; Vahedi, E | 1 |
| Gill, A; Jarolimek, W; Pollock, C; Saad, S; Schilter, H; Stangenberg, S; Wong, MG; Wong, MY; Zaky, A | 1 |
| Hosoda, A; Kohno, T; Masamichi, S; Matsumoto, Y; Toriyama, Y; Tsuji, T; Yoshida, Y | 1 |
| Cai, Y; Chang, D; Ju, S; Lu, CQ; Min, SD; Wang, YC; Xu, TT; Zhang, SJ; Zhao, Z | 1 |
| Ding, Y; Dou, F; Li, Y; Liu, T; Liu, W; Mu, F; Shang, P; Sun, L; Wen, A; Zhang, T; Zhang, Y; Zhu, Z | 1 |
| Bastow, B; Currier, JS; Deleage, C; Douek, DC; Estes, JD; Fichtenbaum, CJ; Kitch, DW; Klingman, KL; Lake, JE; Lederman, MM; Luque, AE; Magyar, C; McComsey, GA; Nelson, SD; Utay, NS; Yeh, E | 1 |
| Badea, O; Bejenaru, C; Bejenaru, LE; Cristea, OM; Ionică, FE; Mogoantă, L; Negreş, S | 1 |
| Gaikwad, AB; Malek, V | 1 |
| Bao, L; Gao, P; Wu, X; Yao, T; Zha, D | 1 |
| Gaikwad, AB; Malek, V; Sankrityayan, H; Sharma, N | 1 |
| Chen, Y; Li, H; Long, H; Luo, C; Peng, F; Wang, Y; Xu, Z; Yin, B | 1 |
| Alter, ML; Chaykovska, L; Hocher, B; Hohmann, M; Klein, T; Kraft, R; Kutil, B; Reichetzeder, C; Tsuprykov, O; von Websky, K | 1 |
| Guan, G; Ma, A; Shao, L; Tian, G; Wang, J; Wang, Y; Zhang, Y | 1 |
| Iwano, M; Kamiyama, K; Kasuno, K; Kimura, H; Mikami, D; Takahashi, N; Torii, K; Yoshida, H | 1 |
| Chen, JA; Gill, AJ; Gross, S; Jarolimek, W; Pollock, CA; Saad, S; Schilter, H; Wong, M; Wong, MG; Zhang, J | 1 |
| Bai, J; Song, Z; Sun, X; Zhang, J; Zhang, L; Zhang, M; Zheng, H | 1 |
| Chen, JH; Chen, LL; Chen, XH; Fu, FY; Tang, MR; Wang, WW; Zhang, FL | 1 |
| Gaikwad, AB; Goru, SK; Kadakol, A; Malek, V; Pandey, A | 1 |
| Cui, QW; Guan, GC; Liu, B; Tian, G; Wang, JK; Zhang, Y; Zhao, NA; Zhu, HL; Zhu, SM | 1 |
| Dash, R; Harnish, P; Kim, PJ; McConnell, MV; Nishimura, D; Toma, I; Yang, PC | 1 |
| Adachi, M; Hayata, M; Hirata, S; Kadowaki, D; Kakizoe, Y; Kitamura, K; Miyasato, Y; Miyoshi, T; Mizumoto, T; Morinaga, J; Mukoyama, M; Nakagawa, T; Narita, Y; Sakai, Y; Uchimura, K; Ueda, M | 1 |
| Alter, M; Ando, R; Antonenko, V; Chaykovska, L; Hasan, AA; Hocher, B; Klein, T; Okuda, S; Rahnenführer, J; Reichetzeder, C; Sharkovska, Y; Tammen, H; Tsuprykov, O; Ueda, S; von Websky, K; Yamagishi, SI | 1 |
| Chang, WT; Chen, ZC; Cheng, JT | 1 |
| Gaikwad, AB; Goru, SK; Kadakol, A; Malek, V; Pandey, A; Sharma, N | 1 |
| Aleksandrowicz, E; Larczyński, W; Lysiak-Szydlowska, W; Renke, M; Rutkowski, B; Rutkowski, P; Tylicki, L | 1 |
| Albayrak, F; Bilen, H; Cetinkaya, R; Halici, Z; Keles, ON; Suleyman, H; Unal, B; Uyanik, A | 1 |
| Hongo, K; Kawai, M; Komukai, K; Mochizuki, S; Morimoto, S; Nagai, M; Seki, S; Taniguchi, I; Yoshimura, M | 1 |
| Hara, Y; Harada, T; Kikuzuki, R; Okada, M; Yamawaki, H | 1 |
| Ara, N; Iuchi, A; Miyoshi, H; Mizuguchi, Y; Nagase, N; Oishi, Y; Oki, T | 1 |
| Aizawa, Y; Gurusamy, N; Kodama, M; Ma, M; Sukumaran, V; Suzuki, K; Thandavarayan, RA; Veeraveedu, PT; Watanabe, K; Yamaguchi, K | 1 |
| Hara, Y; Hoshino, Y; Kosaka, N; Okada, M; Yamawaki, H | 1 |
| Buckley, ST; Ehrhardt, C; Medina, C | 1 |
| Fujimura, T; Fushida, S; Hayashi, H; Kayahara, M; Kitagawa, H; Nakagawara, H; Nakanuma, S; Ohnishi, I; Ohta, T; Okamoto, K; Tajima, H; Takamura, H; Tani, T | 1 |
| Aizawa, Y; Giridharan, VV; Harima, M; Kodama, M; Lakshmanan, AP; Sari, FR; Soetikno, V; Thandavarayan, RA; Watanabe, K | 1 |
| Guan, HS; Meng, XM; Qiao, SB; Shang, Z; Shangguan, HJ; Yang, L | 1 |
| Böhm, M; Friedrich, EB; Jagoda, P; Kazakov, A; Laufs, U; Müller, P; Semenov, A | 1 |
| Hirata, Y; Hishikari, K; Isobe, M; Masumura, M; Nagai, R; Nagashima, A; Ogawa, M; Shimizu, T; Suzuki, J; Takayama, K; Watanabe, R | 1 |
| Abbas, H; Ali, R; Geirsson, A; Hashim, S; Li, W; Sanchez, JA; Singh, M; Tellides, G | 1 |
| Arumugam, S; Harima, M; Kawachi, H; Lakshmanan, AP; Sari, FR; Soetikno, V; Suzuki, K; Watanabe, K | 1 |
| Boor, P; Cohen, CD; Denecke, B; Eitner, F; Floege, J; Gan, L; Konieczny, A; Kunter, U; Neusser, MA; Ostendorf, T; Scholl, T; van Roeyen, CR; Villa, L | 1 |
| Mandarim-de-Lacerda, CA; Pereira, LM | 1 |
| Kira, S; Kobayashi, M; Maeshima, Y; Makino, H; Masuoka, N; Sugiyama, H; Sunami, R; Wang, DH; Yamasaki, Y | 1 |
| Leenen, FH; Liang, B | 1 |
| Ikee, R; Kobayashi, S; Maesato, K; Mano, T; Moriya, H; Ohtake, T; Oka, M | 1 |
| Fagard, RH; Lijnen, PJ; Petrov, VV | 1 |
3 trial(s) available for telmisartan and Cirrhosis
| Article | Year |
|---|---|
Telmisartan Therapy Does Not Improve Lymph Node or Adipose Tissue Fibrosis More Than Continued Antiretroviral Therapy Alone.
Topics: Adipose Tissue; Adult; Antihypertensive Agents; Antiretroviral Therapy, Highly Active; Female; Fibrosis; HIV Infections; Humans; Inflammation; Lymph Nodes; Male; Middle Aged; PPAR gamma; Telmisartan | 2018 |
Telmisartan improves cardiac fibrosis in diabetes through peroxisome proliferator activated receptor δ (PPARδ): from bedside to bench.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Cardiomyopathies; Female; Fibrosis; Humans; Longitudinal Studies; Male; Middle Aged; Myocardium; Myocytes, Cardiac; PPAR gamma; Prospective Studies; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor; Streptozocin; Telmisartan; Time Factors; Translational Research, Biomedical; Treatment Outcome; Up-Regulation; Ventricular Function, Left; Ventricular Remodeling | 2016 |
Dual blockade of the renin-angiotensin-aldosterone system with high-dose angiotensin-converting enzyme inhibitor for nephroprotection: an open, controlled, randomized study.
Topics: Acetylglucosaminidase; Adolescent; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Blood Pressure; Cilazapril; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fibrosis; Humans; Kidney; Kidney Diseases; Male; Middle Aged; Peptide Fragments; Procollagen; Proteinuria; Renin; Renin-Angiotensin System; Telmisartan; Young Adult | 2008 |
43 other study(ies) available for telmisartan and Cirrhosis
| Article | Year |
|---|---|
Antifibrotic effects of low dose SGLT2 Inhibition with empagliflozin in comparison to Ang II receptor blockade with telmisartan in 5/6 nephrectomised rats on high salt diet.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzhydryl Compounds; Dose-Response Relationship, Drug; Fibrosis; Glucosides; Glycosuria; Heart Diseases; Iron; Kidney Diseases; Male; Nephrectomy; Rats; Rats, Wistar; Sequence Analysis, RNA; Sodium-Glucose Transporter 2 Inhibitors; Sodium, Dietary; Telmisartan | 2022 |
Effect of angiotensin II pathway inhibitors on post-surgical adhesion band formation: a potential repurposing of old drugs.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Drug Repositioning; Enalapril; Eosine Yellowish-(YS); Fibrosis; Hematoxylin; Inflammation; Pharmaceutical Preparations; Rats; Rats, Wistar; Sulfhydryl Compounds; Superoxide Dismutase; Telmisartan; Tissue Adhesions | 2022 |
Semicarbazide-sensitive amine oxidase inhibition ameliorates albuminuria and glomerulosclerosis but does not improve tubulointerstitial fibrosis in diabetic nephropathy.
Topics: Albuminuria; Allylamine; Amine Oxidase (Copper-Containing); Animals; Benzamides; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Fibronectins; Fibrosis; Kidney Glomerulus; Kidney Tubules; Leukocyte Common Antigens; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Renal Insufficiency, Chronic; Telmisartan | 2020 |
Telmisartan Exacerbates Cisplatin-Induced Nephrotoxicity in a Mouse Model.
Topics: Acute Kidney Injury; Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Blood Pressure; Blood Urea Nitrogen; Calcium Channel Blockers; Cisplatin; Creatinine; Disease Models, Animal; Drug Synergism; Fibrosis; Humans; Injections, Intraperitoneal; Kidney; Male; Mice; Neoplasms; Severity of Illness Index; Telmisartan | 2020 |
Telmisartan ameliorates cardiac fibrosis and diastolic function in cardiorenal heart failure with preserved ejection fraction.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Cardio-Renal Syndrome; Diastole; Disease Models, Animal; Echocardiography; Fibrosis; Heart Failure; Hypertrophy, Left Ventricular; Male; Natriuretic Peptide, Brain; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Stroke Volume; Telmisartan; Ventricular Function, Left; Ventricular Remodeling | 2021 |
Telmisartan improves vascular remodeling through ameliorating prooxidant and profibrotic mechanisms in hypertension via the involvement of transforming growth factor-β1.
Topics: Antioxidants; Aorta, Thoracic; Benzimidazoles; Benzoates; Collagen Type I; Fibrosis; Gene Expression Regulation; Hypertension; Oxidants; Oxidative Stress; Reactive Oxygen Species; Smad3 Protein; Telmisartan; Transforming Growth Factor beta1; Vascular Remodeling | 2017 |
Comparing the antifibrotic effect on the liver of Telmisartan and Pentoxifylline, in a Wistar rat experimental model.
Topics: Animals; Benzimidazoles; Benzoates; Disease Models, Animal; Fibrosis; Liver; Models, Theoretical; Pentoxifylline; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Telmisartan | 2017 |
Telmisartan and thiorphan combination treatment attenuates fibrosis and apoptosis in preventing diabetic cardiomyopathy.
Topics: Acetylation; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Drug Therapy, Combination; Fibrosis; Histone Acetyltransferases; Histones; Male; Myocytes, Cardiac; Neprilysin; Protease Inhibitors; Protein Processing, Post-Translational; Rats, Wistar; Signal Transduction; Telmisartan; Thiorphan; Ventricular Function, Left; Ventricular Remodeling | 2019 |
Telmisartan attenuates diabetic nephropathy progression by inhibiting the dimerization of angiotensin type-1 receptor and adiponectin receptor-1.
Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dimerization; Disease Models, Animal; Fibrosis; Kidney; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Adiponectin; RNA, Small Interfering; Streptozocin; Telmisartan | 2019 |
Concurrent neprilysin inhibition and renin-angiotensin system modulations prevented diabetic nephropathy.
Topics: Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diminazene; Fibrosis; Inflammation; Kidney; Male; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System; Streptozocin; Telmisartan; Thiorphan | 2019 |
[Effect of telmisartan on expression of metadherin in the kidney of mice with unilateral ureter obstruction].
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Extracellular Matrix Proteins; Fibrosis; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Random Allocation; RNA-Binding Proteins; RNA, Small Interfering; Telmisartan; Transforming Growth Factor beta1; Ureteral Obstruction | 2019 |
Effects of telmisartan and linagliptin when used in combination on blood pressure and oxidative stress in rats with 2-kidney-1-clip hypertension.
Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Benzoates; Blood Pressure; Cardiomegaly; Collagen Type I; Constriction, Pathologic; Cystatin C; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Fibrosis; Heart; Hypertension, Renovascular; Kidney; Linagliptin; Lipoproteins, LDL; Male; Oxidative Stress; Purines; Quinazolines; Random Allocation; Rats; Rats, Wistar; Surgical Instruments; Telmisartan | 2013 |
Telmisartan delays myocardial fibrosis in rats with hypertensive left ventricular hypertrophy by TGF-β1/Smad signal pathway.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blotting, Western; Collagen; Echocardiography; Fibrosis; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Telmisartan; Transforming Growth Factor beta1 | 2014 |
Telmisartan activates endogenous peroxisome proliferator-activated receptor-δ and may have anti-fibrotic effects in human mesangial cells.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Cell Line; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Fatty Acid Binding Protein 3; Fatty Acid-Binding Proteins; Fibrosis; Humans; Ion Channels; Mesangial Cells; Mitochondrial Proteins; Phosphorylation; PPAR delta; Telmisartan; Transforming Growth Factor beta1; Uncoupling Protein 2 | 2014 |
Semicarbazide-sensitive amine oxidase (SSAO) inhibition ameliorates kidney fibrosis in a unilateral ureteral obstruction murine model.
Topics: Amine Oxidase (Copper-Containing); Animals; Benzimidazoles; Benzoates; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Kidney; Kidney Diseases; Mice, Inbred C57BL; Semicarbazides; Telmisartan; Ureteral Obstruction | 2014 |
[Effects of telmisartan on inflammation and fibrosis after acute myocardial infarction in rats].
Topics: Animals; Anterior Wall Myocardial Infarction; Benzimidazoles; Benzoates; C-Reactive Protein; Chemokine CCL2; Drugs, Chinese Herbal; Fibrosis; Inflammation; Interleukin-1beta; Interleukin-6; Matrix Metalloproteinase 9; Myocardial Infarction; Myocardium; NF-kappa B; Rats; Telmisartan; Tumor Necrosis Factor-alpha | 2014 |
Telmisartan reduces atrial arrhythmia susceptibility through the regulation of RAS-ERK and PI3K-Akt-eNOS pathways in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Apoptosis; Arrhythmias, Cardiac; Atrial Remodeling; Benzimidazoles; Benzoates; Blood Pressure; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Heart Rate; Hypertension; Male; Myocytes, Cardiac; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; ras Proteins; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Telmisartan; Time Factors; Valsartan | 2015 |
Insulin sensitizing and cardioprotective effects of Esculetin and Telmisartan combination by attenuating Ang II mediated vascular reactivity and cardiac fibrosis.
Topics: Angiotensin II; Animals; Benzimidazoles; Benzoates; Cardiotonic Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fibrosis; Heart Diseases; Insulin Resistance; Male; Rats; Rats, Wistar; Telmisartan; Treatment Outcome; Umbelliferones; Vasoconstriction | 2015 |
Telmisartan inhibited angiotensin II-induced collagen metabolic imbalance without directly targeting TGF-β 1/Smad signaling pathway in cardiac fibroblasts.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Benzimidazoles; Benzoates; Blotting, Western; Cells, Cultured; Collagen; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fibrosis; Rats; Signal Transduction; Smad Proteins; Telmisartan; Transforming Growth Factor beta1 | 2015 |
Telmisartan in the diabetic murine model of acute myocardial infarction: dual contrast manganese-enhanced and delayed enhancement MRI evaluation of the peri-infarct region.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzimidazoles; Benzoates; Contrast Media; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelial Progenitor Cells; Fibrosis; Flow Cytometry; Gadolinium DTPA; Magnetic Resonance Imaging; Manganese; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron, Transmission; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Predictive Value of Tests; Recovery of Function; Stroke Volume; Telmisartan; Time Factors; Tissue Survival; Ventricular Function, Left | 2016 |
Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Creatinine; Disease Models, Animal; Drug Therapy, Combination; Esters; Fibrosis; Gabexate; Guanidines; Kidney; Male; Oxidative Stress; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Serine Proteinase Inhibitors; Telmisartan | 2016 |
The dipeptidyl peptidase inhibitor linagliptin and the angiotensin II receptor blocker telmisartan show renal benefit by different pathways in rats with 5/6 nephrectomy.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biomarkers; Blood Pressure; Chromatography, Liquid; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Fibrosis; Kidney; Linagliptin; Male; Mass Spectrometry; Nephrectomy; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Transgenic; Renal Insufficiency, Chronic; Renin-Angiotensin System; Signal Transduction; Telmisartan; Time Factors | 2016 |
H2AK119 monoubiquitination regulates Angiotensin II receptor mediated macrophage infiltration and renal fibrosis in type 2 diabetic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blotting, Western; Chemokine CCL2; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fibrosis; Histones; Imidazoles; Kidney; Lysine; Macrophages; Male; Promoter Regions, Genetic; Pyridines; Rats, Wistar; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Telmisartan; Transforming Growth Factor beta1; Ubiquitination | 2016 |
Does telmisartan prevent hepatic fibrosis in rats with alloxan-induced diabetes?
Topics: Alloxan; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Experimental; Fibrosis; Immunohistochemistry; Liver; Male; Microscopy, Electron; Rats; Rats, Wistar; Telmisartan; Transforming Growth Factor beta | 2009 |
Telmisartan predominantly suppresses cardiac fibrosis, rather than hypertrophy, in renovascular hypertensive rats.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Vessels; Cardiomegaly; Cell Size; Coronary Vessels; Fibrosis; Heart Diseases; Hemodynamics; Hypertension, Renovascular; Male; Myocardium; Myocytes, Cardiac; Rats; Rats, Wistar; Telmisartan | 2009 |
Effects of telmisartan on right ventricular remodeling induced by monocrotaline in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Body Weight; Echocardiography; Fibrosis; Histocytochemistry; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocardium; Organ Size; Rats; Rats, Wistar; Stroke Volume; Systole; Telmisartan; Transforming Growth Factor beta1; Ventricular Remodeling | 2009 |
Possible mechanisms of left ventricular torsion evaluated by cardioreparative effects of telmisartan in patients with hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Echocardiography; Feasibility Studies; Female; Fibrosis; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Statistics as Topic; Stroke Volume; Telmisartan; Ventricular Function, Left | 2010 |
Telmisartan, an angiotensin-II receptor blocker ameliorates cardiac remodeling in rats with dilated cardiomyopathy.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Autoimmune Diseases; Benzimidazoles; Benzoates; Cardiomyopathy, Dilated; Chronic Disease; Cytokines; Fibrosis; Heart Failure; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocarditis; Myocardium; Rats; Rats, Inbred Lew; Telmisartan; Ventricular Remodeling | 2010 |
Effects of captopril and telmisartan on matrix metalloproteinase-2 and -9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats.
Topics: Animals; Benzimidazoles; Benzoates; Captopril; Drug Therapy, Combination; Fibrosis; Gene Expression Regulation, Enzymologic; Isoproterenol; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Random Allocation; Rats; Rats, Wistar; Telmisartan; Ventricular Dysfunction, Left | 2010 |
Differential susceptibility to epithelial-mesenchymal transition (EMT) of alveolar, bronchial and intestinal epithelial cells in vitro and the effect of angiotensin II receptor inhibition.
Topics: Angiotensin II Type 1 Receptor Blockers; Antigens, Differentiation; Benzimidazoles; Benzoates; Bronchi; Caco-2 Cells; Cell Movement; Collagen Type I; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Intestinal Mucosa; Intestines; Phosphorylation; Pulmonary Alveoli; Receptors, Angiotensin; Smad2 Protein; Smad3 Protein; Telmisartan; Transforming Growth Factor beta1 | 2010 |
[The role of renin-angiotensin system independent angiotensin II production in progression and fibrosis of intrahepatic cholangiocarcinoma].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cholangiocarcinoma; Disease Progression; Fibrosis; Hepatic Stellate Cells; Humans; Receptor, Angiotensin, Type 1; Telmisartan | 2010 |
Telmisartan attenuates oxidative stress and renal fibrosis in streptozotocin induced diabetic mice with the alteration of angiotensin-(1-7) mas receptor expression associated with its PPAR-γ agonist action.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Benzoates; Collagen Type III; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Hypertrophy; Intracellular Signaling Peptides and Proteins; Kidney; Mice; NADPH Oxidases; Oxidative Stress; Peptidyl-Dipeptidase A; PPAR gamma; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Superoxides; Telmisartan; Transforming Growth Factor beta1; Up-Regulation | 2011 |
Endoplasmic reticulum stress caused by left ventricular hypertrophy in rats: effects of telmisartan.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzimidazoles; Benzoates; Disease Models, Animal; Endoplasmic Reticulum; Fibrosis; Hemodynamics; Hypertrophy, Left Ventricular; Male; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Stress, Physiological; Telmisartan | 2011 |
Ramipril and telmisartan exhibit differential effects in cardiac pressure overload-induced hypertrophy without an additional benefit of the combination of both drugs.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Blood Pressure; Cardiomegaly; Drug Therapy, Combination; Endothelial Cells; Fibrosis; Male; Mice; Mice, Inbred C57BL; Myocardium; Ramipril; Stem Cells; Telmisartan | 2013 |
Different roles of PPAR-γ activity on physiological and pathological alteration after myocardial ischemia.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Cells, Cultured; Disease Models, Animal; Drug Partial Agonism; Fibrosis; Hypertrophy, Left Ventricular; Male; Matrix Metalloproteinase 2; Myocardial Infarction; Myocardium; Pioglitazone; PPAR gamma; Rats; Rats, Sprague-Dawley; Stroke Volume; Telmisartan; Thiazolidinediones; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2012 |
Modulation of transforming growth factor-β signaling and extracellular matrix production in myxomatous mitral valves by angiotensin II receptor blockers.
Topics: Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Cells, Cultured; Collagen; Elastic Tissue; Extracellular Matrix Proteins; Fibrosis; Gene Expression Regulation; Genetic Diseases, X-Linked; Heart Defects, Congenital; Humans; Losartan; Mitral Valve Insufficiency; Mitral Valve Prolapse; Myxoma; Polymerase Chain Reaction; Signal Transduction; Smad2 Protein; Smad3 Protein; Telmisartan; Tetrazoles; Transforming Growth Factor beta; Vimentin | 2012 |
Curcumin alleviates oxidative stress, inflammation, and renal fibrosis in remnant kidney through the Nrf2-keap1 pathway.
Topics: Animals; Benzimidazoles; Benzoates; Blood Pressure; Blood Urea Nitrogen; Creatinine; Curcumin; Cyclooxygenase 2; Fibronectins; Fibrosis; Heme Oxygenase (Decyclizing); Inflammation; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Kidney; Kidney Diseases; Male; Nephrectomy; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Signal Transduction; Telmisartan; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2013 |
Late angiotensin II receptor blockade in progressive rat mesangioproliferative glomerulonephritis: new insights into mechanisms.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Blood Pressure; Cell Dedifferentiation; Cell Line; Chemokine CCL20; Cytoprotection; Disease Models, Animal; Fibrosis; Gene Expression Profiling; Gene Expression Regulation; Glomerular Mesangium; Glomerulonephritis, Membranoproliferative; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Inflammation; Isoantibodies; Macrophages; Male; Mice; Nephrectomy; Podocytes; Proteinuria; Rats; Rats, Wistar; Receptors, CCR6; Receptors, Platelet-Derived Growth Factor; RNA Interference; RNA, Messenger; Telmisartan; Time Factors; Transfection | 2013 |
Effect of telmisartan on preexistent cardiac and renal lesions in spontaneously hypertensive mature rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Blood Pressure; Cell Size; Fibrosis; Kidney; Kidney Glomerulus; Male; Microcirculation; Myocardium; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Telmisartan; Time Factors | 2004 |
Telmisartan inhibits both oxidative stress and renal fibrosis after unilateral ureteral obstruction in acatalasemic mice.
Topics: Acatalasia; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Disease Models, Animal; Fibrosis; Immunohistochemistry; In Situ Nick-End Labeling; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Mice; Mice, Inbred C3H; Mice, Mutant Strains; NADPH Oxidases; Oxidative Stress; Telmisartan; Treatment Outcome; Ureteral Obstruction | 2005 |
Prevention of salt-induced hypertension and fibrosis by AT1-receptor blockers in Dahl S rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Benzoates; Blood Pressure; Cardiomegaly; Dose-Response Relationship, Drug; Fibrosis; Heart Rate; Hypertension; Hypertrophy; Kidney; Losartan; Male; Myocardium; Organ Specificity; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium, Dietary; Telmisartan | 2008 |
Pathological regression by angiotensin II type 1 receptor blockade in patients with mesangial proliferative glomerulonephritis.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biopsy; Creatinine; Female; Fibrosis; Glomerulonephritis, Membranoproliferative; Humans; Immunoglobulin A; Kidney Glomerulus; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Retrospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan; Vasodilation | 2008 |
Induction of cardiac fibrosis by angiotensin II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Cells, Cultured; Collagen; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Fibroblasts; Fibrosis; Lisinopril; Male; Myocardium; Rats; Rats, Wistar; Telmisartan; Time Factors; Transforming Growth Factor beta | 2000 |