Page last updated: 2024-08-24

telmisartan and Alloxan Diabetes

telmisartan has been researched along with Alloxan Diabetes in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	9 (16.36)	29.6817
2010's	41 (74.55)	24.3611
2020's	5 (9.09)	2.80

Authors

Authors	Studies
Abdel Hamid, AM; Abdel Monsef, AS; Abdo, W; Ahmeda, AF; Amer, ME; Antar, SA; El-Moselhy, LE; Farage, AE; Kamel, EM; Mahmoud, AM; Taha, RS	1
Escalada, FJ; Fernández-Seara, MA; Garcia-Fernandez, N; Mora-Gutiérrez, JM; Orbe, J; Páramo, JA; Riera, M; Rodríguez, JA; Slon Roblero, MF; Soler, MJ	1
Gill, A; Jarolimek, W; Pollock, C; Saad, S; Schilter, H; Stangenberg, S; Wong, MG; Wong, MY; Zaky, A	1
Advani, A; Advani, SL; Batchu, SN; Kabir, MG; Kaur, H; Klein, T; Liu, Y; Yerra, VG	1
Cao, J; Jiao, X; Jin, W; Lei, Z; Li, D; Wang, J; Zhang, Y; Zhang, Z	1
Ding, X; Li, H; Li, W; Shen, X; Sun, Z; Wu, X	1
Ichikawa, T; Imoto, A; Ishii, N; Katagiri, M; Kawakami, F; Kurosaki, Y; Takenaka, T; Yokoba, M	1
Gaikwad, AB; Malek, V	1
Bao, L; Gao, P; Wu, X; Yao, T; Zha, D	1
Gaikwad, AB; Malek, V; Sankrityayan, H; Sharma, N	1
Daiber, A; Foster, C; Ghaemi Kerahrodi, J; Hausding, M; Jansen, T; Knorr, M; Kröller-Schön, S; Li, H; Mollnau, H; Münzel, T; Oelze, M; Schulz, E; Teutsch, C; Wenzel, P; Wu, Z; Zinßius, E	1
Abuohashish, HM; Ahmed, MM; Al-Rejaie, SS; Alhomida, AS; Ola, MS	1
Jena, GB; Kushwaha, S	1
Li, LY; Luo, R; Sun, LT; Tian, FS; Xiong, HL; Zhao, ZQ; Zheng, XL	1
Chaudagar, KK; Mehta, AA	1
Chang Li, J; Du, GT; Hong, H; Hu, M; Liu, GJ; Long, Y; Mei, ZL; Miao, MX; Wang, C	1
Gangadharan Komala, M; Gross, S; Huang, C; Mather, A; Mudaliar, H; Panchapakesan, U; Pegg, K; Pollock, CA; Shen, S	1
Abuohashish, HM; Ahmed, MM; Al-Rejaie, SS; Aleisa, AM; AlSharari, SD; Arrejaie, AS	1
Guo, Z; Jing, X; Liu, J; Wang, L; Wu, J; Yan, X	2
Breitbart, E; Ishai, E; Mendel, I; Shoham, A; Yacov, N	1
El-Kadem, AH; El-Mahdy, NA; El-Sayad, ME	1
Chang, WT; Chen, ZC; Cheng, JT	1
Gaikwad, AB; Goru, SK; Kadakol, A; Malek, V; Pandey, A; Sharma, N	1
Aswar, M; Aswar, U; Chepurwar, S; Shintre, S	1
Deng, A; Liu, J; Wang, J; Yao, L; Zhao, H	1
Asano, M; Fujinami, A; Fukui, M; Harusato, I; Hasegawa, G; Hosoda, H; Kitawaki, J; Nakamura, N; Obayashi, H; Ohta, M; Sakabe, K; Senmaru, T; Shiraishi, E; Tanaka, M; Yamasaki, M	1
Albayrak, F; Bilen, H; Cetinkaya, R; Halici, Z; Keles, ON; Suleyman, H; Unal, B; Uyanik, A	1
Emre, M; Kavak, S; Unlugenc, H	1
Fukuoka, N; Inoue, T; Kikumoto, Y; Kitagawa, M; Maeshima, Y; Makino, H; Masuoka, N; Morinaga, H; Ogino, K; Saeki, M; Sugiyama, H; Takiue, K; Wang, DH	1
Heinig, M; Kosugi, T; Matsuo, S; Nakagawa, T; Nakayama, T	1
Kashihara, N; Kobayashi, S; Kuwabara, A; Sasaki, T; Satoh, M; Tomita, N	1
Gaikwad, AB; Mulay, SR; Tikoo, K	1
Arora, S; Arya, DS; Bhatt, TK; Das, P; Goyal, S; Kumari, S; Sharma, A	1
Horiuchi, M; Iwai, M; Iwanami, J; Jing, F; Min, LJ; Mogi, M; Sakata, A; Tsukuda, K	1
Guo, Z; Qin, Z; Wei, P; Zheng, C	1
Arya, DS; Bharti, S; Bhatia, J; Goyal, SN; Nag, TC; Ray, R	1
Aizawa, Y; Giridharan, VV; Harima, M; Kodama, M; Lakshmanan, AP; Sari, FR; Soetikno, V; Thandavarayan, RA; Watanabe, K	1
Jain, A; Rao, RP; Srinivasan, B	1
Limor, R; Oron, Y; Rosenthal, T; Stern, N; Younis, F	1
Goyal, BR; Goyal, RK; Mehta, AA; Parmar, K	1
Horiuchi, M; Iwanami, J; Jing, F; Min, LJ; Mogi, M; Ohshima, K; Shudou, M; Tsukuda, K	1
Li, M; Li, W; Mao, L; Sun, X; Xiang, H; Xiao, X; Yu, M; Zhang, H; Zhang, Q	1
Tawfik, MK	1
Guo, Z; Li, J; Xu, G; Zhang, R	1
Alter, ML; Henze, A; Hocher, B; Klein, T; Krause-Relle, K; Ott, IM; Raila, J; Sharkovska, Y; Tsuprykov, O; von Websky, K	1
Cheng, S; Li, H; Li, J; Li, X; Yuan, L	1
Aksoy, A; Becher, UM; Lütjohann, D; Mueller, CF; Nickenig, G; Tiyerili, V; Wassmann, S	1
Dhakad, PK; Joshi, M; Joshi, S; Kanawat, DS; Kurmi, MK; Mishra, A; Raikwar, SK; Sharma, AK; Sharma, P; Srinivasan, BP; Srivastava, V	1
Deng, AG; Liu, JS; Wang, JQ; Yao, LJ; Zhao, H	1
Bauersachs, J; Ertl, G; Flierl, U; Menninger, S; Schäfer, A; Tas, P; Vogt, C	1
Fujita, T; Leiper, J; Onozato, ML; Palm, F; Tojo, A; Wilcox, CS	1
Goyal, BR; Goyal, RK; Mehta, AA; Mesariya, P	1
Imamura, Y; Ishida, S; Kurihara, T; Nagai, N; Noda, K; Oike, Y; Okano, H; Ozawa, Y; Shinoda, K; Tsubota, K	1
Audeval-Gerard, C; Champeroux, P; Richard, S; Wienen, W	1

Trials

1 trial(s) available for telmisartan and Alloxan Diabetes

Article	Year
Telmisartan improves cardiac fibrosis in diabetes through peroxisome proliferator activated receptor δ (PPARδ): from bedside to bench. Cardiovascular diabetology, 2016, 08-12, Volume: 15, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Cardiomyopathies; Female; Fibrosis; Humans; Longitudinal Studies; Male; Middle Aged; Myocardium; Myocytes, Cardiac; PPAR gamma; Prospective Studies; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor; Streptozocin; Telmisartan; Time Factors; Translational Research, Biomedical; Treatment Outcome; Up-Regulation; Ventricular Function, Left; Ventricular Remodeling	2016

Article

Year

Telmisartan improves cardiac fibrosis in diabetes through peroxisome proliferator activated receptor δ (PPARδ): from bedside to bench.

Cardiovascular diabetology, 2016, 08-12, Volume: 15, Issue:1

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Cardiomyopathies; Female; Fibrosis; Humans; Longitudinal Studies; Male; Middle Aged; Myocardium; Myocytes, Cardiac; PPAR gamma; Prospective Studies; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor; Streptozocin; Telmisartan; Time Factors; Translational Research, Biomedical; Treatment Outcome; Up-Regulation; Ventricular Function, Left; Ventricular Remodeling

2016

Other Studies

54 other study(ies) available for telmisartan and Alloxan Diabetes

Article	Year
Telmisartan attenuates diabetic nephropathy by mitigating oxidative stress and inflammation, and upregulating Nrf2/HO-1 signaling in diabetic rats. Life sciences, 2022, Feb-15, Volume: 291 Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Heme Oxygenase (Decyclizing); Inflammation; Kidney; Male; Molecular Docking Simulation; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Telmisartan	2022
MMP-10 is Increased in Early Stage Diabetic Kidney Disease and can be Reduced by Renin-Angiotensin System Blockade. Scientific reports, 2020, 01-08, Volume: 10, Issue:1 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Animals; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Male; Matrix Metalloproteinase 10; Mice; Mice, Inbred C57BL; Middle Aged; Prognosis; Renin-Angiotensin System; Telmisartan	2020
Semicarbazide-sensitive amine oxidase inhibition ameliorates albuminuria and glomerulosclerosis but does not improve tubulointerstitial fibrosis in diabetic nephropathy. PloS one, 2020, Volume: 15, Issue:6 Topics: Albuminuria; Allylamine; Amine Oxidase (Copper-Containing); Animals; Benzamides; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Fibronectins; Fibrosis; Kidney Glomerulus; Kidney Tubules; Leukocyte Common Antigens; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Renal Insufficiency, Chronic; Telmisartan	2020
Lung and Kidney ACE2 and TMPRSS2 in Renin-Angiotensin System Blocker-Treated Comorbid Diabetic Mice Mimicking Host Factors That Have Been Linked to Severe COVID-19. Diabetes, 2021, Volume: 70, Issue:3 Topics: Age Factors; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; COVID-19; Diabetes Mellitus, Experimental; Diet, High-Fat; Immunoblotting; In Situ Hybridization; Kidney; Lung; Male; Mice; Ramipril; Receptors, Coronavirus; Reverse Transcriptase Polymerase Chain Reaction; SARS-CoV-2; Serine Endopeptidases; Telmisartan	2021
Autoantibody against angiotensin II type I receptor induces pancreatic β-cell apoptosis via enhancing autophagy. Acta biochimica et biophysica Sinica, 2021, May-21, Volume: 53, Issue:6 Topics: Adenine; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Autoantibodies; Autophagy; Cell Line, Tumor; Cell Survival; Diabetes Mellitus, Experimental; Immunization; Immunoglobulin G; Insulin Secretion; Insulin-Secreting Cells; Male; Rats; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan; Up-Regulation	2021
Telmisartan ameliorates adipoR1 and adipoR2 expression via PPAR-γ activation in the coronary artery and VSMCs. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 95 Topics: Anilides; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Glucose; Coronary Vessels; Diabetes Mellitus, Experimental; Gene Expression Regulation; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; PPAR gamma; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Telmisartan; Tumor Necrosis Factor-alpha	2017
Oxidative stress increases megalin expression in the renal proximal tubules during the normoalbuminuric stage of diabetes mellitus. American journal of physiology. Renal physiology, 2018, 03-01, Volume: 314, Issue:3 Topics: Animals; Antioxidants; Cell Line; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose; Humans; Hydrogen Peroxide; Kidney Tubules, Proximal; Low Density Lipoprotein Receptor-Related Protein-2; Male; Oxidants; Oxidative Stress; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Telmisartan; Time Factors; Up-Regulation	2018
Telmisartan and thiorphan combination treatment attenuates fibrosis and apoptosis in preventing diabetic cardiomyopathy. Cardiovascular research, 2019, 02-01, Volume: 115, Issue:2 Topics: Acetylation; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Drug Therapy, Combination; Fibrosis; Histone Acetyltransferases; Histones; Male; Myocytes, Cardiac; Neprilysin; Protease Inhibitors; Protein Processing, Post-Translational; Rats, Wistar; Signal Transduction; Telmisartan; Thiorphan; Ventricular Function, Left; Ventricular Remodeling	2019
Telmisartan attenuates diabetic nephropathy progression by inhibiting the dimerization of angiotensin type-1 receptor and adiponectin receptor-1. Life sciences, 2019, Mar-15, Volume: 221 Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dimerization; Disease Models, Animal; Fibrosis; Kidney; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Adiponectin; RNA, Small Interfering; Streptozocin; Telmisartan	2019
Concurrent neprilysin inhibition and renin-angiotensin system modulations prevented diabetic nephropathy. Life sciences, 2019, Mar-15, Volume: 221 Topics: Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diminazene; Fibrosis; Inflammation; Kidney; Male; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System; Streptozocin; Telmisartan; Thiorphan	2019
Effects of telmisartan or amlodipine monotherapy versus telmisartan/amlodipine combination therapy on vascular dysfunction and oxidative stress in diabetic rats. Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:5 Topics: Amlodipine; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Experimental; Drug Combinations; Endothelium, Vascular; Male; Organ Culture Techniques; Oxidative Stress; Rats; Rats, Wistar; Telmisartan; Treatment Outcome	2013
Telmisartan ameliorates neurotrophic support and oxidative stress in the retina of streptozotocin-induced diabetic rats. Neurochemical research, 2013, Volume: 38, Issue:8 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Glucose; Blotting, Western; Brain-Derived Neurotrophic Factor; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Glutathione; Male; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Telmisartan	2013
Telmisartan ameliorates germ cell toxicity in the STZ-induced diabetic rat: studies on possible molecular mechanisms. Mutation research, 2013, Jul-04, Volume: 755, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzimidazoles; Benzoates; Biomarkers; Blotting, Western; Deoxyguanosine; Diabetes Mellitus, Experimental; DNA Damage; Germ Cells; Immunoenzyme Techniques; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sperm Count; Telmisartan; Tyrosine	2013
Angiotensin II receptor blocker telmisartan prevents new-onset diabetes in pre-diabetes OLETF rats on a high-fat diet: evidence of anti-diabetes action. Canadian journal of diabetes, 2013, Volume: 37, Issue:3 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Glucose; Blood Pressure; Body Weight; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Gene Expression; Hypoglycemic Agents; Inflammation; Insulin Resistance; Male; Metformin; Pioglitazone; Rats; Rats, Inbred OLETF; Telmisartan; Thiazolidinediones	2013
Effect of telmisartan on VEGF-induced and VEGF-independent angiogenic responsiveness of coronary endothelial cells in normal and streptozotocin (STZ)-induced diabetic rats. Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:8 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Experimental; Endothelial Cells; Heart; Male; Myocardial Reperfusion Injury; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; PPAR gamma; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction; Telmisartan; Vascular Endothelial Growth Factor A	2014
Telmisartan treatment ameliorates memory deficits in streptozotocin-induced diabetic mice via attenuating cerebral amyloidosis. Journal of pharmacological sciences, 2014, Volume: 124, Issue:4 Topics: Administration, Oral; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Angiotensin II Type 1 Receptor Blockers; Animals; Aspartic Acid Endopeptidases; Benzimidazoles; Benzoates; Cerebral Amyloid Angiopathy; Cerebral Cortex; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Hippocampus; Male; Memory Disorders; Mice; Mice, Inbred ICR; Peptide Fragments; Receptor for Advanced Glycation End Products; Streptozocin; Telmisartan; Transcription Factor RelA; Treatment Outcome	2014
Inhibition of kidney proximal tubular glucose reabsorption does not prevent against diabetic nephropathy in type 1 diabetic eNOS knockout mice. PloS one, 2014, Volume: 9, Issue:11 Topics: Albuminuria; Animals; Benzhydryl Compounds; Benzimidazoles; Benzoates; Blood Glucose; Chemokine CCL2; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibronectins; Glucose Transporter Type 1; Glucosides; Hypoglycemic Agents; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; RNA, Messenger; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Streptozocin; Telmisartan; Toll-Like Receptor 2; Transforming Growth Factor beta1	2014
Telmisartan inhibits hyperalgesia and inflammatory progression in a diabetic neuropathic pain model of Wistar rats. Neurosciences (Riyadh, Saudi Arabia), 2015, Volume: 20, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Cytokines; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hyperalgesia; Inflammation; Male; Motor Activity; Pain Measurement; Physical Stimulation; Rats; Rats, Wistar; Sciatic Nerve; Telmisartan	2015
[Effects of telmisartan on the expression of adiponectin and its receptors in testes of type 1 diabetic rats]. Zhonghua yi xue za zhi, 2015, Jun-09, Volume: 95, Issue:22 Topics: AMP-Activated Protein Kinases; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Insulin; Male; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Telmisartan; Testis	2015
Effect of Telmisartan or Insulin on the Expression of Adiponectin and its Receptors in the Testis of Streptozotocin-Induced Diabetic Rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2016, Volume: 48, Issue:6 Topics: Adiponectin; AMP-Activated Protein Kinases; Animals; Benzimidazoles; Benzoates; Blotting, Western; Body Weight; Diabetes Mellitus, Experimental; Heme Oxygenase-1; Insulin; Interleukin-6; Male; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Organ Size; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Adiponectin; RNA, Messenger; Streptozocin; Telmisartan; Testis; Tumor Necrosis Factor-alpha	2016
Treatment with Oxidized Phospholipids Directly Inhibits Nonalcoholic Steatohepatitis and Liver Fibrosis Without Affecting Steatosis. Digestive diseases and sciences, 2016, Volume: 61, Issue:9 Topics: Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Glucose; Blotting, Western; Cell Movement; Cytokines; Dendritic Cells; Diabetes Mellitus, Experimental; Diet, High-Fat; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glycerophosphates; Glycerylphosphorylcholine; Hepatic Stellate Cells; Humans; Inflammation; Kupffer Cells; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Monocytes; Non-alcoholic Fatty Liver Disease; Phospholipids; Pyridinium Compounds; Real-Time Polymerase Chain Reaction; Telmisartan; Toll-Like Receptor 2; Toll-Like Receptor 4; Triglycerides	2016
Combination of telmisartan with sildenafil ameliorate progression of diabetic nephropathy in streptozotocin-induced diabetic model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 81 Topics: Animals; Benzimidazoles; Benzoates; Blood Glucose; Blood Urea Nitrogen; Body Weight; Cholesterol, LDL; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Glycation End Products, Advanced; Interleukin-1beta; Kidney; Nitric Oxide; Proteinuria; Rats; Sildenafil Citrate; Streptozocin; Superoxide Dismutase; Telmisartan; Transforming Growth Factor beta1	2016
H2AK119 monoubiquitination regulates Angiotensin II receptor mediated macrophage infiltration and renal fibrosis in type 2 diabetic rats. Biochimie, 2016, Volume: 131 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blotting, Western; Chemokine CCL2; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fibrosis; Histones; Imidazoles; Kidney; Lysine; Macrophages; Male; Promoter Regions, Genetic; Pyridines; Rats, Wistar; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Telmisartan; Transforming Growth Factor beta1; Ubiquitination	2016
Telmisartan attenuates diabetes induced depression in rats. Pharmacological reports : PR, 2017, Volume: 69, Issue:2 Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Benzimidazoles; Benzoates; Brain; Depression; Depressive Disorder; Diabetes Mellitus; Diabetes Mellitus, Experimental; Female; Fluoxetine; Hydrocortisone; Interleukin-1beta; Interleukin-6; Male; Metformin; Nitric Oxide; Pilot Projects; Rats; Rats, Wistar; Renin-Angiotensin System; Streptozocin; Swimming; Telmisartan	2017
Effect of Micardis on the expression of renal medulla aquaporin-2 in diabetic mice. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2008, Volume: 28, Issue:3 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aquaporin 2; Benzimidazoles; Benzoates; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Expression Regulation; Immunohistochemistry; Kidney; Kidney Medulla; Male; Mice; Mice, Inbred C57BL; Telmisartan	2008
Telmisartan, an angiotensin II type 1 receptor blocker, prevents the development of diabetes in male Spontaneously Diabetic Torii rats. European journal of pharmacology, 2009, Mar-01, Volume: 605, Issue:1-3 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blotting, Western; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Gene Expression Regulation; Insulin-Secreting Cells; Male; NADPH Oxidases; Oxidative Stress; Pancreas; Rats; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Telmisartan	2009
Does telmisartan prevent hepatic fibrosis in rats with alloxan-induced diabetes? European journal of pharmacology, 2009, Jul-01, Volume: 614, Issue:1-3 Topics: Alloxan; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Experimental; Fibrosis; Immunohistochemistry; Liver; Male; Microscopy, Electron; Rats; Rats, Wistar; Telmisartan; Transforming Growth Factor beta	2009
The effects of telmisartan on mechanical responses of left ventricular papillary muscle in rats with streptozotocin-induced diabetes mellitus. Acta diabetologica, 2010, Volume: 47 Suppl 1 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Models, Animal; Heart Ventricles; Humans; Male; Myocardial Contraction; Papillary Muscles; Rats; Rats, Wistar; Streptozocin; Telmisartan	2010
Sensitization to alloxan-induced diabetes and pancreatic cell apoptosis in acatalasemic mice. Biochimica et biophysica acta, 2010, Volume: 1802, Issue:2 Topics: Acatalasia; Alloxan; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzimidazoles; Benzoates; Blood Glucose; Body Weight; Catalase; Cell Death; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Homozygote; Hyperglycemia; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Mice, Mutant Strains; Superoxide Dismutase; Telmisartan	2010
eNOS knockout mice with advanced diabetic nephropathy have less benefit from renin-angiotensin blockade than from aldosterone receptor antagonists. The American journal of pathology, 2010, Volume: 176, Issue:2 Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Delivery Systems; Enalapril; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mineralocorticoid Receptor Antagonists; Nitric Oxide Synthase Type III; Renin-Angiotensin System; Streptozocin; Telmisartan; Treatment Failure	2010
In vivo visualization of glomerular microcirculation and hyperfiltration in streptozotocin-induced diabetic rats. Microcirculation (New York, N.Y. : 1994), 2010, Volume: 17, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Benzimidazoles; Benzoates; Capillary Permeability; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glomerular Filtration Rate; Kidney Glomerulus; Male; Microcirculation; Microscopy, Fluorescence, Multiphoton; Rats; Rats, Sprague-Dawley; Renal Circulation; Telmisartan	2010
Combination of aspirin with telmisartan suppresses the augmented TGFbeta/smad signaling during the development of streptozotocin-induced type I diabetic nephropathy. Chemico-biological interactions, 2010, Apr-29, Volume: 185, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzimidazoles; Benzoates; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gene Expression Regulation; Inflammation; Male; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Streptozocin; Telmisartan; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2010
Modulation of PPAR-gamma by telmisartan protects the heart against myocardial infarction in experimental diabetes. Chemico-biological interactions, 2010, May-14, Volume: 185, Issue:3 Topics: Animals; Benzimidazoles; Benzoates; Cardiotonic Agents; Diabetes Mellitus, Experimental; Disease Models, Animal; Heart; Male; Myocardial Infarction; Myocardium; PPAR gamma; Rats; Rats, Wistar; Telmisartan	2010
Low dose of telmisartan prevents ischemic brain damage with peroxisome proliferator-activated receptor-gamma activation in diabetic mice. Journal of hypertension, 2010, Volume: 28, Issue:8 Topics: Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Benzimidazoles; Benzoates; Blood Flow Velocity; Blood Pressure; Cerebral Cortex; Cytokines; Diabetes Mellitus, Experimental; Drug Antagonism; Drug Therapy, Combination; Infarction, Middle Cerebral Artery; Losartan; Male; Mice; Mice, Inbred C57BL; PPAR gamma; Superoxides; Telmisartan	2010
Effect of telmisartan on the expression of cardiac adiponectin and its receptor 1 in type 2 diabetic rats. The Journal of pharmacy and pharmacology, 2011, Volume: 63, Issue:1 Topics: Adiponectin; AMP-Activated Protein Kinases; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gene Expression Regulation; Glucose Transporter Type 4; Male; Myocardium; Phosphorylation; Rats; Rats, Wistar; Receptors, Adiponectin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Streptozocin; Telmisartan	2011
Telmisartan, a dual ARB/partial PPAR-γ agonist, protects myocardium from ischaemic reperfusion injury in experimental diabetes. Diabetes, obesity & metabolism, 2011, Volume: 13, Issue:6 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Experimental; Myocardial Reperfusion Injury; Myocardium; PPAR gamma; Rats; Telmisartan	2011
Telmisartan attenuates oxidative stress and renal fibrosis in streptozotocin induced diabetic mice with the alteration of angiotensin-(1-7) mas receptor expression associated with its PPAR-γ agonist action. Free radical research, 2011, Volume: 45, Issue:5 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Benzoates; Collagen Type III; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Hypertrophy; Intracellular Signaling Peptides and Proteins; Kidney; Mice; NADPH Oxidases; Oxidative Stress; Peptidyl-Dipeptidase A; PPAR gamma; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Superoxides; Telmisartan; Transforming Growth Factor beta1; Up-Regulation	2011
Dual therapy versus monotherapy of trandolapril and telmisartan on diabetic nephropathy in experimentally induced type 2 diabetes mellitus rats. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2011, Volume: 12, Issue:3 Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Therapy, Combination; Fasting; Female; Fibronectins; Indoles; Male; Rats; Telmisartan; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha	2011
Prophylactic treatment with telmisartan induces tissue-specific gene modulation favoring normal glucose homeostasis in Cohen-Rosenthal diabetic hypertensive rats. Metabolism: clinical and experimental, 2012, Volume: 61, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Glucose; Chemoprevention; Diabetes Mellitus, Experimental; Gene Expression Regulation; Homeostasis; Hypertension; Male; Organ Specificity; Rats; Rats, Inbred Strains; Telmisartan; Up-Regulation	2012
Beneficial role of telmisartan on cardiovascular complications associated with STZ-induced type 2 diabetes in rats. Pharmacological reports : PR, 2011, Volume: 63, Issue:4 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Benzimidazoles; Benzoates; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dyslipidemias; Female; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Streptozocin; Telmisartan	2011
Peroxisome proliferator-activated receptor-γ activation with angiotensin II type 1 receptor blockade is pivotal for the prevention of blood-brain barrier impairment and cognitive decline in type 2 diabetic mice. Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:5 Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Benzimidazoles; Benzoates; Blood Glucose; Blood-Brain Barrier; Blotting, Western; Cognition Disorders; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Losartan; Male; Maze Learning; Mice; Mice, Inbred C57BL; PPAR gamma; Random Allocation; Sensitivity and Specificity; Telmisartan	2012
Telmisartan improves kidney function through inhibition of the oxidative phosphorylation pathway in diabetic rats. Journal of molecular endocrinology, 2012, Volume: 49, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Gene Expression Profiling; Gene Expression Regulation; Hypertrophy; Kidney; Male; NADH Dehydrogenase; Oxidative Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Telmisartan	2012
Renoprotective activity of telmisartan versus pioglitazone on ischemia/reperfusion induced renal damage in diabetic rats. European review for medical and pharmacological sciences, 2012, Volume: 16, Issue:5 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glutathione; Hypoglycemic Agents; Inflammation Mediators; Kidney; Lipid Peroxidation; Lipid Peroxides; Oxidative Stress; Pioglitazone; Rats; Reperfusion Injury; Superoxide Dismutase; Telmisartan; Thiazolidinediones; Time Factors; Tumor Necrosis Factor-alpha	2012
Effect of telmisartan on the expression of adiponectin receptors and nicotinamide adenine dinucleotide phosphate oxidase in the heart and aorta in type 2 diabetic rats. Cardiovascular diabetology, 2012, Aug-08, Volume: 11 Topics: Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Abdominal; Benzimidazoles; Benzoates; Chemokine CCL2; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gene Expression Regulation; Glucose Transporter Type 4; Male; Myocardium; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Rats; Rats, Wistar; Receptors, Adiponectin; RNA, Messenger; Telmisartan	2012
DPP-4 inhibition on top of angiotensin receptor blockade offers a new therapeutic approach for diabetic nephropathy. Kidney & blood pressure research, 2012, Volume: 36, Issue:1 Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Benzoates; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dipeptidyl Peptidase 4; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Linagliptin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; Oxidative Stress; Purines; Quinazolines; Streptozocin; Telmisartan; Treatment Outcome	2012
Blockade of renin angiotensin system increased resistance to STZ-induced diabetes in rats with long-term high-fat diet. Experimental diabetes research, 2012, Volume: 2012 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzimidazoles; Benzoates; Blood Glucose; Caspase 3; Diabetes Mellitus, Experimental; Diet, High-Fat; Glucose Clamp Technique; Immunohistochemistry; Inflammation Mediators; Insulin; Insulin Resistance; Insulin-Secreting Cells; Interleukin-1beta; Male; NF-kappa B; Prediabetic State; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Streptozocin; Telmisartan; Time Factors	2012
AT1-receptor-deficiency induced atheroprotection in diabetic mice is partially mediated via PPARγ. Cardiovascular diabetology, 2013, Feb-01, Volume: 12 Topics: Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Apolipoproteins E; Atherosclerosis; Benzimidazoles; Benzoates; Blood Glucose; Diabetes Mellitus, Experimental; Endothelium, Vascular; Female; Mice; Mice, Knockout; Oxidative Stress; PPAR gamma; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan	2013
Dual therapy of vildagliptin and telmisartan on diabetic nephropathy in experimentally induced type 2 diabetes mellitus rats. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2014, Volume: 15, Issue:4 Topics: Adamantane; Albuminuria; Animals; Benzimidazoles; Benzoates; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Body Weight; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diastole; Drug Therapy, Combination; Fasting; Hypoglycemic Agents; Male; Nitriles; Pyrrolidines; Rats, Wistar; Systole; Telmisartan; Vildagliptin	2014
Effect of telmisartan on expression of protein kinase C-alpha in kidneys of diabetic mice. Acta pharmacologica Sinica, 2007, Volume: 28, Issue:6 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Experimental; Kidney; Male; Mice; Mice, Inbred C57BL; Protein Kinase C-alpha; Random Allocation; Telmisartan; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A	2007
Telmisartan improves vascular function and reduces platelet activation in rats with streptozotocin-induced diabetes mellitus. Pharmacological research, 2007, Volume: 56, Issue:3 Topics: Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Platelets; Cell Adhesion Molecules; Diabetes Mellitus, Experimental; Diethylamines; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Male; Microfilament Proteins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Phosphoproteins; Phosphorylation; Platelet Activation; Rats; Rats, Wistar; Reactive Oxygen Species; Telmisartan; Vasodilation; Vasodilator Agents	2007
Expression of NG,NG-dimethylarginine dimethylaminohydrolase and protein arginine N-methyltransferase isoforms in diabetic rat kidney: effects of angiotensin II receptor blockers. Diabetes, 2008, Volume: 57, Issue:1 Topics: Amidohydrolases; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Experimental; Female; Kidney; Nephrons; Protein-Arginine N-Methyltransferases; Rats; Rats, Sprague-Dawley; Reference Values; Telmisartan	2008
Effect of telmisartan on cardiovascular complications associated with streptozotocin diabetic rats. Molecular and cellular biochemistry, 2008, Volume: 314, Issue:1-2 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Female; Heart Rate; Hypertrophy, Left Ventricular; Models, Biological; Rats; Rats, Wistar; Streptozocin; Telmisartan	2008
Angiotensin II type 1 receptor signaling contributes to synaptophysin degradation and neuronal dysfunction in the diabetic retina. Diabetes, 2008, Volume: 57, Issue:8 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Cell Line; Diabetes Mellitus, Experimental; Extracellular Signal-Regulated MAP Kinases; Immunoblotting; Mice; Mice, Inbred C57BL; Neurons; Oncogene Protein v-akt; Phosphorylation; Receptor, Angiotensin, Type 1; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; STAT3 Transcription Factor; Synaptophysin; Telmisartan; Tetrazoles; Ubiquitination; Valine; Valsartan	2008
Comparative antihypertensive and renoprotective effects of telmisartan and lisinopril after long-term treatment in hypertensive diabetic rats. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2001, Volume: 2, Issue:1 Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Hyperglycemia; Hypertension; Kidney; Kidney Glomerulus; Lisinopril; Male; Organ Size; Proteinuria; Rats; Rats, Inbred SHR; Reference Values; Telmisartan	2001