Page last updated: 2024-10-28

tele-methylhistamine and Parkinson Disease

tele-methylhistamine has been researched along with Parkinson Disease in 1 studies

tele-methylhistamine: histamine methyltransferase antagonist
N(tele)-methylhistamine : A primary amino compound that is the N(tele)-methyl derivative of histamine.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
"We investigated histamine concentration in post-mortem brain samples of patients with Parkinson's disease (PD, n = 24), multiple system atrophy (MSA, n = 8) and age-matched controls (n = 27)."7.71Increased brain histamine levels in Parkinson's disease but not in multiple system atrophy. ( Anichtchik, OV; Eriksson, KS; Kalimo, H; Kaslin, J; Panula, P; Rinne, JO; Röyttä, M; Tuomisto, L, 2002)
"We investigated histamine concentration in post-mortem brain samples of patients with Parkinson's disease (PD, n = 24), multiple system atrophy (MSA, n = 8) and age-matched controls (n = 27)."3.71Increased brain histamine levels in Parkinson's disease but not in multiple system atrophy. ( Anichtchik, OV; Eriksson, KS; Kalimo, H; Kaslin, J; Panula, P; Rinne, JO; Röyttä, M; Tuomisto, L, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rinne, JO1
Anichtchik, OV1
Eriksson, KS1
Kaslin, J1
Tuomisto, L1
Kalimo, H1
Röyttä, M1
Panula, P1

Other Studies

1 other study available for tele-methylhistamine and Parkinson Disease

ArticleYear
Increased brain histamine levels in Parkinson's disease but not in multiple system atrophy.
    Journal of neurochemistry, 2002, Volume: 81, Issue:5

    Topics: Aged; Brain; Brain Chemistry; Female; Globus Pallidus; Histamine; Humans; Immunohistochemistry; Male

2002