tele-methylhistamine has been researched along with Hepatic Encephalopathy in 2 studies
tele-methylhistamine: histamine methyltransferase antagonist
N(tele)-methylhistamine : A primary amino compound that is the N(tele)-methyl derivative of histamine.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histamine was assayed by HPLC; tele-methylhistamine by GC-MS." | 1.32 | Increased concentrations of histamine and its metabolite, tele-methylhistamine and down-regulation of histamine H3 receptor sites in autopsied brain tissue from cirrhotic patients who died in hepatic coma. ( Butterworth, RF; Lozeva, V; Tarhanen, J; Tuomisto, L, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lozeva, V | 1 |
| Tuomisto, L | 2 |
| Tarhanen, J | 2 |
| Butterworth, RF | 1 |
| Fogel, WA | 1 |
| Andrzejewski, W | 1 |
| Sasiak, K | 1 |
| Granerus, G | 1 |
| Lonnqvist, B | 1 |
2 other studies available for tele-methylhistamine and Hepatic Encephalopathy
| Article | Year |
|---|---|
Increased concentrations of histamine and its metabolite, tele-methylhistamine and down-regulation of histamine H3 receptor sites in autopsied brain tissue from cirrhotic patients who died in hepatic coma.
Topics: Adult; Aged; Brain Chemistry; Case-Control Studies; Down-Regulation; Hepatic Encephalopathy; Histami | 2003 |
Can urinary N-tele methylimidazoleacetic acid (t-MeImAA) serve as a marker of histaminergic activity in hepatic encephalopathy (HE)?
Topics: Animals; Biomarkers; Brain Chemistry; Chromatography, High Pressure Liquid; Digestive System Physiol | 2002 |