tele-methylhistamine has been researched along with Alzheimer Disease in 2 studies
tele-methylhistamine: histamine methyltransferase antagonist
N(tele)-methylhistamine : A primary amino compound that is the N(tele)-methyl derivative of histamine.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histaminergic neurons enhance cognition and memory, suggesting that their degeneration may contribute to the cognitive decline of AD." | 1.36 | CSF levels of the histamine metabolite tele-methylhistamine are only slightly decreased in Alzheimer's disease. ( Arrang, JM; Callebert, J; Motawaj, M; Peoc'h, K, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Motawaj, M | 2 |
| Peoc'h, K | 1 |
| Callebert, J | 1 |
| Arrang, JM | 2 |
| Burban, A | 1 |
| Davenas, E | 1 |
2 other studies available for tele-methylhistamine and Alzheimer Disease
| Article | Year |
|---|---|
CSF levels of the histamine metabolite tele-methylhistamine are only slightly decreased in Alzheimer's disease.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Biomarkers; Female; Histamine | 2010 |
Activation of brain histaminergic neurotransmission: a mechanism for cognitive effects of memantine in Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Brain; Brain-Derived Neurotrophic Factor; Calcium; Cognition; Dizocilpin | 2011 |