telavancin has been researched along with Meningitis--Bacterial* in 1 studies
1 other study(ies) available for telavancin and Meningitis--Bacterial
Article | Year |
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Efficacy of telavancin against penicillin-resistant pneumococci and Staphylococcus aureus in a rabbit meningitis model and determination of kinetic parameters.
The penetration of telavancin was 2% into inflamed meninges and ca. 1 per thousand into noninflamed meninges after two intravenous injections (30 mg/kg of body weight). In experimental meningitis, telavancin was significantly superior to vancomycin combined with ceftriaxone against a penicillin-resistant pneumococcal strain. Against a methicillin-sensitive staphylococcal strain, telavancin was slightly but not significantly superior to vancomycin. Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Disease Models, Animal; Lipoglycopeptides; Meningitis, Bacterial; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Penicillin Resistance; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae | 2006 |