telavancin and Meningitis--Bacterial

telavancin has been researched along with Meningitis--Bacterial* in 1 studies

Other Studies

1 other study(ies) available for telavancin and Meningitis--Bacterial

ArticleYear
Efficacy of telavancin against penicillin-resistant pneumococci and Staphylococcus aureus in a rabbit meningitis model and determination of kinetic parameters.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:2

    The penetration of telavancin was 2% into inflamed meninges and ca. 1 per thousand into noninflamed meninges after two intravenous injections (30 mg/kg of body weight). In experimental meningitis, telavancin was significantly superior to vancomycin combined with ceftriaxone against a penicillin-resistant pneumococcal strain. Against a methicillin-sensitive staphylococcal strain, telavancin was slightly but not significantly superior to vancomycin.

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Disease Models, Animal; Lipoglycopeptides; Meningitis, Bacterial; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Penicillin Resistance; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae

2006