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tegafur and Nasopharyngeal Neoplasms

tegafur has been researched along with Nasopharyngeal Neoplasms in 13 studies

Nasopharyngeal Neoplasms: Tumors or cancer of the NASOPHARYNX.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to analyze the safety and feasibility of low-dose apatinib combined with S-1 as a second-line therapy or beyond in Chinese patients with pulmonary and/or hepatic metastases of nasopharyngeal carcinoma (NPC)."7.96Safety and Feasibility of Low-Dose Apatinib Combined with S-1 as the Second-Line Therapy or Beyond in Chinese Patients with Pulmonary and Hepatic Metastasis of Nasopharyngeal Carcinoma. ( Chen, J; Huang, X; Lin, J; Wu, G; Zhang, S; Zhou, L, 2020)
"The study was aimed to evaluate the impact of accumulated oral tegafur-uracil (UFUR) as maintenance chemotherapy on overall survival (OS) and disease-free survival (DFS) rates after concurrent chemoradiotherapy (CCRT) for complete remission (CR) in non-distant metastatic TNM stage IV nasopharyngeal carcinoma (NPC)."7.91Evaluation of oral tegafur-uracil as metronomic therapy following concurrent chemoradiotherapy in patients with non-distant metastatic TNM stage IV nasopharyngeal carcinoma. ( Chao, TY; Chen, JH; Ho, CL; Huang, WY; Lee, JC, 2019)
"The purpose of this study was to analyze the safety and feasibility of low-dose apatinib combined with S-1 as a second-line therapy or beyond in Chinese patients with pulmonary and/or hepatic metastases of nasopharyngeal carcinoma (NPC)."3.96Safety and Feasibility of Low-Dose Apatinib Combined with S-1 as the Second-Line Therapy or Beyond in Chinese Patients with Pulmonary and Hepatic Metastasis of Nasopharyngeal Carcinoma. ( Chen, J; Huang, X; Lin, J; Wu, G; Zhang, S; Zhou, L, 2020)
"The study was aimed to evaluate the impact of accumulated oral tegafur-uracil (UFUR) as maintenance chemotherapy on overall survival (OS) and disease-free survival (DFS) rates after concurrent chemoradiotherapy (CCRT) for complete remission (CR) in non-distant metastatic TNM stage IV nasopharyngeal carcinoma (NPC)."3.91Evaluation of oral tegafur-uracil as metronomic therapy following concurrent chemoradiotherapy in patients with non-distant metastatic TNM stage IV nasopharyngeal carcinoma. ( Chao, TY; Chen, JH; Ho, CL; Huang, WY; Lee, JC, 2019)
"Distant metastases rate (DMR) was significantly reduced with CRT (14."2.71Concurrent and adjuvant chemotherapy for nasopharyngeal carcinoma: a factorial study. ( Au, GK; Chan, RT; Cheng, AC; Choy, DD; Chua, DT; Kwok, CC; Kwong, DL; Kwong, PW; Law, MW; Sham, JS; Wan, KY; Wu, PM; Yau, CC, 2004)
" Most adverse events were mild."1.40Safety and efficacy of S-1 chemotherapy in recurrent and metastatic nasopharyngeal carcinoma patients after failure of platinum-based chemotherapy: multi-institutional retrospective analysis. ( Chen, ZB; Cheng, H; Lin, Z; Liu, YM; Ou, XQ; Peng, PJ; Tang, YN; Wang, SY; Wu, X; Zeng, LJ; Zhang, HY, 2014)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's0 (0.00)18.2507
2000's3 (23.08)29.6817
2010's5 (38.46)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Chen, JH1
Huang, WY1
Ho, CL1
Chao, TY1
Lee, JC1
Zong, J1
Xu, H1
Chen, B1
Guo, Q1
Xu, Y1
Chen, C1
Weng, Y1
Zheng, W1
Pan, J1
Lin, S1
Zhou, L1
Lin, J1
Wu, G1
Chen, J1
Huang, X1
Zhang, S1
Lv, T1
Wang, Y1
Ou, D1
Liu, P1
Qin, S1
Liu, L1
Lou, P1
Wang, X1
Twu, CW1
Wang, WY1
Chen, CC1
Liang, KL1
Jiang, RS1
Wu, CT1
Shih, YT1
Lin, PJ1
Liu, YC1
Lin, JC1
Peng, PJ1
Cheng, H1
Ou, XQ1
Zeng, LJ1
Wu, X1
Liu, YM1
Lin, Z1
Tang, YN1
Wang, SY1
Zhang, HY1
Chen, ZB1
Okita, J1
Hatta, C1
Terada, T1
Saeki, N1
Ogasawara, H1
Kakibuchi, M1
Kamikonya, N1
Sakagami, M1
Kwong, DL1
Sham, JS1
Au, GK1
Chua, DT1
Kwong, PW1
Cheng, AC1
Wu, PM1
Law, MW1
Kwok, CC1
Yau, CC1
Wan, KY1
Chan, RT1
Choy, DD1
Park, JH1
Nam, SY1
Lee, SW1
Kim, SB1
Kim, SY1
Lee, BJ1
Cho, KJ1
Kim, JH1
Ahn, SD1
Shin, SS1
Choi, SH1
Ahn, JH1
Choi, EK1
Inuyama, Y1
Horiuchi, M1
Kohno, N1
Mashino, S1
Ozu, R1
Asaoka, K1
Tsujii, H1
Kamada, T1
Tsuji, H1
Takamura, A1
Matsuoka, Y1
Usubuchi, H1
Irie, G1
Furukawa, M2
Ohoka, H2
Sakashita, H1
Umeda, R2
Kamide, M1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Single-agent Capecitabine as Adjuvant Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma: A Phase 3, Multicentre, Randomised Controlled Trial (CAN)[NCT02958111]Phase 3406 participants (Actual)Interventional2017-01-31Active, not recruiting
Randomized, Placebo-controlled, Double-blind Phase II Clinical Trial of Neoadjuvant and Adjuvant Anti-PD-1 Antibody Toripalimab Immunotherapy Combined With Concurrent Chemoradiotherapy for High-risk Nasopharyngeal Carcinoma[NCT03925090]Phase 2150 participants (Anticipated)Interventional2019-12-08Active, not recruiting
Phase Ⅲ Trial of Concurrent Chemoradiotherapy Followed by Adjuvant Chemotherapy (GP Versus PF) in Patients With N2-3 Nasopharyngeal Carcinoma[NCT03321539]Phase 3216 participants (Anticipated)Interventional2017-10-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for tegafur and Nasopharyngeal Neoplasms

ArticleYear
IMRT combined with S-1 concurrent chemoradiotherapy in locally advanced nasopharyngeal carcinoma: a prospective phase II study.
    Investigational new drugs, 2019, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cisplati

2019
Concurrent and adjuvant chemotherapy for nasopharyngeal carcinoma: a factorial study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Jul-01, Volume: 22, Issue:13

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcin

2004
Clinical trials with oral Futraful (INN: Tegafur) in cancer of the head and neck.
    Clinical oncology, 1981, Volume: 7, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Adenoid Cystic; Car

1981

Other Studies

10 other studies available for tegafur and Nasopharyngeal Neoplasms

ArticleYear
Evaluation of oral tegafur-uracil as metronomic therapy following concurrent chemoradiotherapy in patients with non-distant metastatic TNM stage IV nasopharyngeal carcinoma.
    Head & neck, 2019, Volume: 41, Issue:11

    Topics: Administration, Metronomic; Administration, Oral; Adult; Antimetabolites, Antineoplastic; Chemoradio

2019
Maintenance chemotherapy using S-1 following definitive chemoradiotherapy in patients with N3 nasopharyngeal carcinoma.
    Radiation oncology (London, England), 2019, Oct-22, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Chemoradiotherapy; Drug Combinations; Female; Humans; Maintenance Chemother

2019
Safety and Feasibility of Low-Dose Apatinib Combined with S-1 as the Second-Line Therapy or Beyond in Chinese Patients with Pulmonary and Hepatic Metastasis of Nasopharyngeal Carcinoma.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asian People; Car

2020
Metronomic adjuvant chemotherapy improves treatment outcome in nasopharyngeal carcinoma patients with postradiation persistently detectable plasma Epstein-Barr virus deoxyribonucleic acid.
    International journal of radiation oncology, biology, physics, 2014, May-01, Volume: 89, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chemotherapy, Adjuvant; Cisplatin

2014
Metronomic adjuvant chemotherapy improves treatment outcome in nasopharyngeal carcinoma patients with postradiation persistently detectable plasma Epstein-Barr virus deoxyribonucleic acid.
    International journal of radiation oncology, biology, physics, 2014, May-01, Volume: 89, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chemotherapy, Adjuvant; Cisplatin

2014
Metronomic adjuvant chemotherapy improves treatment outcome in nasopharyngeal carcinoma patients with postradiation persistently detectable plasma Epstein-Barr virus deoxyribonucleic acid.
    International journal of radiation oncology, biology, physics, 2014, May-01, Volume: 89, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chemotherapy, Adjuvant; Cisplatin

2014
Metronomic adjuvant chemotherapy improves treatment outcome in nasopharyngeal carcinoma patients with postradiation persistently detectable plasma Epstein-Barr virus deoxyribonucleic acid.
    International journal of radiation oncology, biology, physics, 2014, May-01, Volume: 89, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chemotherapy, Adjuvant; Cisplatin

2014
Metronomic adjuvant chemotherapy improves treatment outcome in nasopharyngeal carcinoma patients with postradiation persistently detectable plasma Epstein-Barr virus deoxyribonucleic acid.
    International journal of radiation oncology, biology, physics, 2014, May-01, Volume: 89, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chemotherapy, Adjuvant; Cisplatin

2014
Metronomic adjuvant chemotherapy improves treatment outcome in nasopharyngeal carcinoma patients with postradiation persistently detectable plasma Epstein-Barr virus deoxyribonucleic acid.
    International journal of radiation oncology, biology, physics, 2014, May-01, Volume: 89, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chemotherapy, Adjuvant; Cisplatin

2014
Metronomic adjuvant chemotherapy improves treatment outcome in nasopharyngeal carcinoma patients with postradiation persistently detectable plasma Epstein-Barr virus deoxyribonucleic acid.
    International journal of radiation oncology, biology, physics, 2014, May-01, Volume: 89, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chemotherapy, Adjuvant; Cisplatin

2014
Metronomic adjuvant chemotherapy improves treatment outcome in nasopharyngeal carcinoma patients with postradiation persistently detectable plasma Epstein-Barr virus deoxyribonucleic acid.
    International journal of radiation oncology, biology, physics, 2014, May-01, Volume: 89, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chemotherapy, Adjuvant; Cisplatin

2014
Metronomic adjuvant chemotherapy improves treatment outcome in nasopharyngeal carcinoma patients with postradiation persistently detectable plasma Epstein-Barr virus deoxyribonucleic acid.
    International journal of radiation oncology, biology, physics, 2014, May-01, Volume: 89, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chemotherapy, Adjuvant; Cisplatin

2014
Safety and efficacy of S-1 chemotherapy in recurrent and metastatic nasopharyngeal carcinoma patients after failure of platinum-based chemotherapy: multi-institutional retrospective analysis.
    Drug design, development and therapy, 2014, Volume: 8

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma; Disease Progression; Drug Combinations; Fem

2014
Concurrent chemo-radiotherapy for nasopharyngeal carcinoma.
    Auris, nasus, larynx, 2004, Volume: 31, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Car

2004
Radiation therapy with UFT and low dose weekly cisplatin for nasopharyngeal carcinoma.
    Auris, nasus, larynx, 2005, Volume: 32, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co

2005
Improved results in the treatment of nasopharyngeal carcinoma using combined radiotherapy and chemotherapy.
    Cancer, 1989, May-01, Volume: 63, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma,

1989
Synergistic antitumor activity of cisplatin and UFT in nude mice bearing transplantable nasopharyngeal hybridoma.
    Auris, nasus, larynx, 1989, Volume: 16, Issue:3

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Administration S

1989
[Combination chemotherapy with cisplatin and UFT malignant tumors of the head and neck--experimental study of human nasopharyngeal carcinoma (A2L/AH) xenografted to nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Admin

1988
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