tegafur has been researched along with Mouth Neoplasms in 61 studies
Mouth Neoplasms: Tumors or cancer of the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we conducted a phase I study to examine local control of S-1 in the combination with DOC using super-selective intra-arterial infusion with oral cancer." | 2.74 | [Clinical phase I trial of S-1 in the combination with DOC using super-selective intra-arterial infusion with oral cancer]. ( Harada, K; Horinaga, D; Mano, T; Mihara, M; Okafuji, M; Uchida, K; Ueyama, Y; Wada, N, 2009) |
| "Patients with pathologically confirmed squamous cell carcinoma and at least one measurable lesion were enrolled." | 2.73 | Multi-institutional phase II trial of S-1 in patients with oral squamous cell carcinoma. ( Hamakawa, H; Harada, K; Nagahata, S; Nagayama, M; Osaki, T; Ryoke, K; Sato, M; Ueyama, Y; Yoshimura, Y, 2008) |
| "We studied the usefulness and safety of long-term administration of uracil and tegafur (UFT) after primary therapy of the malignant tumor in jaw and oral cavity regions randomized controlled trial." | 2.67 | [Multiple cooperative study of UFT-adjuvant chemotherapy for malignant tumor in the jaw and oral cavities. The Oral Surgery Malignant Tumor Research Association in Kanto Kohshinetsu District]. ( Asakura, A; Fukuda, H; Hagiwara, T; Kobayashi, A; Kotani, A; Nemoto, K; Sakamoto, H; Sunada, O; Takaku, S; Tamura, M, 1994) |
| " We analyzed the clinical response, survival rate, acute adverse events, and late swallowing toxicity." | 1.51 | Long-term efficacy and toxicity of concurrent chemoradiotherapy with nedaplatin and S-1 for head and neck squamous cell carcinoma. ( Ohashi, T; Ohnishi, M; Okuda, H; Takada, N; Takagi, C; Takahashi, H, 2019) |
| "In our department, patients with oral squamous cell carcinoma(OSCC)received preoperative chemotherapy containing S-1 to prevent the growth and dissemination of tumors during the waiting time before definitive surgery." | 1.51 | [Clinicopathological Evaluation of Preoperative Chemotherapy Containing S-1 as a Treatment for Patients with Oral Squamous Cell Carcinoma during Waiting Time for Surgery]. ( Amino, K; Imai, T; Iwai, S; Kanesaki, T; Katou, I; Matsumiya, Y; Meshii, N; Nakazawa, M; Niki, A; Omae, M; Onishi, T; Ota, Y; Suematsu, M; Sumi, T; Takeshita, A; Ueda, M, 2019) |
| "Tegafur-uracil treatment is a useful, effective, and well-tolerated anticancer treatment for advanced oral cancer." | 1.48 | The Impact of Metronomic Adjuvant Chemotherapy in Patients with Advanced Oral Cancer. ( Chang, DC; Chen, G; Chen, MK; Chien, SY; Hsieh, MY, 2018) |
| "We clinically analyzed 8 oral squamous cell carcinoma patients showing a complete response(CR)to chemotherapy with S-1 alone." | 1.37 | [Clinical analyses of oral squamous cell carcinoma patients showing a complete response to chemotherapy with S-1 alone]. ( Aoki, M; Iwamoto, O; Koga, C; Koga, M; Kusukawa, J; Nakamura, M, 2011) |
| " The present study indicates that further investigation is needed to determine the best dosing and dosing schedule." | 1.37 | [The clinical effect of combination therapy for oral cancer with S-1, superselective intra-arterial chemotherapy, and radiation therapy]. ( Fukumoto, S; Higuchi, T; Horinouchi, Y; Uehara, S; Yamamoto, C; Yasumori, K; Yoshida, M; Yoshikawa, H, 2011) |
| " In this study, the response of human OSCC cells to Lentinan alone and in combination with S-1 was examined using nude mouse xenograft models." | 1.36 | Effects of lentinan alone and in combination with fluoropyrimidine anticancer agent on growth of human oral squamous cell carcinoma in vitro and in vivo. ( Harada, K; Itashiki, Y; Takenawa, T; Ueyama, Y, 2010) |
| "Cepharanthine is a biscoclaurine alkaloid extracted from Stephania cepharantha Hayata, which is widely used for the treatment of many acute and chronic diseases, and can exert antitumor effects on several human cancer cells." | 1.35 | Effects of cepharanthine alone and in combination with fluoropyrimidine anticancer agent, S-1, on tumor growth of human oral squamous cell carcinoma xenografts in nude mice. ( Ferdous, T; Harada, K; Itashiki, Y; Mano, T; Mori, Y; Takii, M; Ueyama, Y, 2009) |
| "Approximately 50% of oral squamous cell carcinomas (OSCC) exhibit cervical lymph node metastasis." | 1.35 | S-1 mediates the inhibition of lymph node metastasis in oral cancer cells. ( Ando, Y; Hatori, M; Kurihara, Y; Sato, H; Shintani, S; Shirota, T; Tachikawa, T; Takayama, S, 2009) |
| "A 76-year-old patient with oral squamous cell carcinoma was treated by chemotherapy with S-1." | 1.34 | [A case of oral squamous cell carcinoma responding to S-1]. ( Bando, T; Harada, K; Tamatani, T; Yoshida, H, 2007) |
| "In the patients with oral squamous cell carcinoma (OSCC), S-1 was given orally according to a 4-week application followed by 2-week rest regimen (4-week regimen), or a 2-week application followed by a 1-week rest regimen (2-week regimen)." | 1.34 | Investigation of optimal schedule of concurrent radiotherapy with S-1 for oral squamous cell carcinoma. ( Ferdous, T; Harada, K; Yoshida, H, 2007) |
| "Twenty-five patients with oral squamous cell carcinoma (OSCC) received S-1 80 mg/m2/day." | 1.33 | Thymidylate synthase expression in oral squamous cell carcinoma predicts response to S-1. ( Harada, K; Kawashima, Y; Sato, M; Yoshida, H, 2006) |
| "Twenty patients with previously untreated squamous cell carcinoma of the oral cavity and oropharynx (T4; 8, T2; 12 patients) were treated with targeted transfemoral intra-arterial carboplatin infusion with concurrent hyperfractionated radiotherapy and the administration of tegafur/uracil (UFT)." | 1.33 | Targeted intra-arterial carboplatin chemoradiotherapy and tegafur/uracil for oral and oropharyngeal cancer. ( Ikemura, K; Imada, H; Inenaga, R; Korogi, Y; Nakamura, S; Onari, N; Oya, R; Takagi, S, 2006) |
| "We report a case of advanced squamous cell carcinoma in the left buccal mucosa, upper gingiva, and maxillary sinus (T4N0M0) showing a complete response to oral chemotherapy with TS-1." | 1.32 | [An advanced case of squamous cell carcinoma in the left buccal mucosa, upper gingiva, and maxillary sinus (T4N0M0) showing a complete response to chemotherapy with TS-1]. ( Mishima, K; Nakamura, H; Obara, S; Yamamoto, K; Yoshimura, Y, 2004) |
| "Human oral cancer cell lines were used as subcutaneous xenografts in nude mice." | 1.32 | Combined effects of the oral fluoropyrimidine anticancer agent, S-1 and radiation on human oral cancer cells. ( Harada, K; Kawaguchi, S; Onoue, T; Sato, M; Yoshida, H, 2004) |
| "In this study, 109 oral squamous cell carcinomas were investigated for the immunohistochemical expression of TS and DPD proteins." | 1.31 | Thymidylate synthase and dihydropyrimidine dehydrogenase expression in oral squamous cell carcinoma: an immunohistochemical and clinicopathologic study. ( Kawasaki, G; Mizuno, A; Yanamoto, S; Yoshitomi, I, 2002) |
| "UFT was administered orally at a dosage of 200 mg/day, 2 times a day, to patients over 80 years of age with oral cancer." | 1.31 | [5-FU concentration in the serum and the tumor tissue after administration of UFT 200 mg/day to patients over 80 years of age with oral cancer]. ( Fukuda, J; Hayatsu, M; Hoshina, H; Iida, A; Kaji, M; Miyamoto, T; Miyaura, Y; Nagashima, K; Ono, K; Takagi, R; Tsurumaki, H, 2000) |
| "A 73-year-old male with squamous cell carcinoma of the oral floor (T1N0M0), who had not consented to radical treatment was treated with UFT by oral administration alone." | 1.31 | [A case of squamous cell carcinoma of the oral floor showing a complete response to oral administration of UFT]. ( Fujisawa, A; Ikeda, H; Inokuchi, T; Kitamura, A; Nonaka, M; Ohba, S; Tobita, T; Uehara, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (6.56) | 18.7374 |
| 1990's | 4 (6.56) | 18.2507 |
| 2000's | 30 (49.18) | 29.6817 |
| 2010's | 22 (36.07) | 24.3611 |
| 2020's | 1 (1.64) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshida, R | 2 |
| Nagata, M | 1 |
| Hirosue, A | 1 |
| Kawahara, K | 1 |
| Nakamoto, M | 1 |
| Hirayama, M | 1 |
| Takahashi, N | 1 |
| Matsuoka, Y | 1 |
| Sakata, J | 1 |
| Nakashima, H | 1 |
| Arita, H | 1 |
| Hiraki, A | 4 |
| Shinohara, M | 4 |
| Kikuchi, K | 1 |
| Nakayama, H | 4 |
| Takakura, H | 1 |
| Domae, S | 1 |
| Ono, T | 3 |
| Sasaki, A | 2 |
| Hsieh, MY | 2 |
| Chen, G | 1 |
| Chang, DC | 1 |
| Chien, SY | 1 |
| Chen, MK | 2 |
| Okuda, H | 1 |
| Ohnishi, M | 1 |
| Takahashi, H | 1 |
| Takagi, C | 1 |
| Takada, N | 1 |
| Ohashi, T | 1 |
| Matsumiya, Y | 1 |
| Imai, T | 1 |
| Takeshita, A | 1 |
| Meshii, N | 1 |
| Katou, I | 1 |
| Iwai, S | 2 |
| Suematsu, M | 1 |
| Omae, M | 1 |
| Kanesaki, T | 1 |
| Ota, Y | 1 |
| Onishi, T | 1 |
| Amino, K | 1 |
| Sumi, T | 2 |
| Niki, A | 1 |
| Ueda, M | 1 |
| Nakazawa, M | 4 |
| Seki-Soda, M | 1 |
| Sano, T | 1 |
| Koshi, H | 1 |
| Yokoo, S | 2 |
| Oyama, T | 1 |
| Ferdous, T | 3 |
| Harada, K | 13 |
| Kin, T | 1 |
| Harada, T | 1 |
| Ueyama, Y | 5 |
| Kasamatsu, A | 1 |
| Uzawa, K | 1 |
| Minakawa, Y | 1 |
| Ishige, S | 1 |
| Kasama, H | 1 |
| Endo-Sakamoto, Y | 1 |
| Ogawara, K | 1 |
| Shiiba, M | 1 |
| Takiguchi, Y | 1 |
| Tanzawa, H | 1 |
| Watanabe, H | 1 |
| Itoh, H | 1 |
| Tsuchiya, Y | 1 |
| Miyagi, N | 1 |
| Sugiyama, T | 1 |
| Nakai, Y | 1 |
| Shinozaki, Y | 1 |
| Noguchi, T | 1 |
| Jinbu, Y | 1 |
| Kusama, M | 1 |
| Negishi, A | 1 |
| Ogawa, M | 1 |
| Kosugi, K | 1 |
| Takayama, Y | 1 |
| Gomi, A | 1 |
| Miyazaki, H | 1 |
| Kishimoto, K | 1 |
| Yoshida, S | 1 |
| Yoshihama, Y | 2 |
| Nishiyama, A | 1 |
| Okafuji, M | 1 |
| Mano, T | 2 |
| Mihara, M | 1 |
| Uchida, K | 1 |
| Horinaga, D | 1 |
| Wada, N | 1 |
| Itashiki, Y | 2 |
| Takii, M | 1 |
| Mori, Y | 1 |
| Koga, M | 3 |
| Anegawa, E | 2 |
| Yoh, J | 1 |
| Tsuyama, H | 1 |
| Sakaino, H | 1 |
| Iwamoto, O | 3 |
| Koga, C | 3 |
| Kusukawa, J | 3 |
| Nomura, T | 1 |
| Murakami, R | 2 |
| Toya, R | 1 |
| Teshima, K | 2 |
| Nakahara, A | 1 |
| Hirai, T | 2 |
| Yoshitake, Y | 1 |
| Ota, K | 1 |
| Obayashi, T | 1 |
| Yamashita, Y | 3 |
| Oya, N | 1 |
| Yamashita, T | 1 |
| Toida, M | 1 |
| Kato, K | 1 |
| Long, NK | 1 |
| Miyazaki, Y | 1 |
| Asaka, Y | 1 |
| Hatakeyama, D | 1 |
| Yonemoto, K | 1 |
| Makita, H | 1 |
| Kato, Y | 1 |
| Shibata, T | 1 |
| Sato, H | 1 |
| Hatori, M | 1 |
| Ando, Y | 1 |
| Kurihara, Y | 1 |
| Takayama, S | 1 |
| Shirota, T | 1 |
| Tachikawa, T | 1 |
| Shintani, S | 3 |
| Harada, H | 2 |
| Omura, K | 2 |
| Kawasaki, G | 3 |
| Yoshitomi, I | 3 |
| Yanamoto, S | 3 |
| Yamada, S | 2 |
| Kawano, T | 1 |
| Mizuno, A | 3 |
| Takenawa, T | 1 |
| Nagai, H | 2 |
| Takamaru, N | 1 |
| Ohe, G | 1 |
| Uchida, D | 2 |
| Tamatani, T | 2 |
| Fujisawa, K | 1 |
| Iwamoto, S | 1 |
| Miyamoto, Y | 2 |
| Nakamura, M | 1 |
| Aoki, M | 2 |
| Yamamoto, C | 1 |
| Yoshikawa, H | 1 |
| Fukumoto, S | 1 |
| Higuchi, T | 1 |
| Yoshida, M | 1 |
| Horinouchi, Y | 1 |
| Uehara, S | 2 |
| Yasumori, K | 1 |
| Nakaguchi, Y | 1 |
| Tsujita, N | 1 |
| Tomitaka, E | 1 |
| Furusawa, M | 1 |
| Tamura, T | 1 |
| Tanio, K | 1 |
| Kidani, K | 1 |
| Ogawa, N | 1 |
| Kodani, I | 1 |
| Ryoke, K | 2 |
| Tomioka, H | 1 |
| Fujimori, S | 1 |
| Kurita, H | 2 |
| Azegami, T | 1 |
| Koike, T | 2 |
| Ohtsuka, A | 1 |
| Kobayashi, H | 2 |
| Tanaka, K | 1 |
| Kurashina, K | 2 |
| Kawano, K | 1 |
| Goto, H | 1 |
| Kanda, T | 1 |
| Yanagisawa, S | 1 |
| Yamamoto, K | 1 |
| Obara, S | 1 |
| Mishima, K | 1 |
| Nakamura, H | 1 |
| Yoshimura, Y | 2 |
| Kawaguchi, S | 2 |
| Onoue, T | 1 |
| Yoshida, H | 7 |
| Sato, M | 7 |
| Ohnishi, T | 2 |
| Chisoku, H | 2 |
| Katagiri, W | 1 |
| Doi, T | 1 |
| Takase, T | 1 |
| Yui, S | 2 |
| Miwa, Y | 1 |
| Fukuda, Y | 2 |
| Kishino, M | 2 |
| Yura, Y | 2 |
| Kawashima, Y | 4 |
| Ohmae, M | 1 |
| Hino, S | 1 |
| Nakashiro, K | 1 |
| Hamakawa, H | 2 |
| Miyazawa, H | 1 |
| Oya, R | 1 |
| Takagi, S | 1 |
| Inenaga, R | 1 |
| Nakamura, S | 1 |
| Ikemura, K | 1 |
| Onari, N | 1 |
| Imada, H | 1 |
| Korogi, Y | 1 |
| Oshikawa, T | 1 |
| Okamoto, M | 1 |
| Ahmed, SU | 1 |
| Tano, T | 1 |
| Maruoka, Y | 1 |
| Ando, T | 1 |
| Ogiuchi, Y | 1 |
| Ogiuchi, H | 1 |
| Tezuka, M | 1 |
| Bando, T | 1 |
| Nagayama, M | 1 |
| Nagahata, S | 1 |
| Osaki, T | 1 |
| Nakata, A | 1 |
| Fukuda, M | 1 |
| Iwanami, Y | 1 |
| Ito, H | 1 |
| Takano, H | 1 |
| Nanjo, H | 1 |
| Inuyama, Y | 2 |
| Horiuchi, M | 1 |
| Kohno, N | 2 |
| Mashino, S | 1 |
| Ozu, R | 1 |
| Asaoka, K | 1 |
| Kaneda, T | 1 |
| Fujimoto, Y | 1 |
| Shinozuka, J | 1 |
| Su, P | 1 |
| Grau, JJ | 1 |
| Palombo, H | 1 |
| Estapé, J | 1 |
| Mañé, JM | 1 |
| Blanch, JL | 1 |
| Vilalta, A | 1 |
| Castro, V | 1 |
| Biete, A | 1 |
| Kotani, A | 1 |
| Sunada, O | 1 |
| Tamura, M | 1 |
| Takaku, S | 1 |
| Kobayashi, A | 1 |
| Asakura, A | 1 |
| Sakamoto, H | 1 |
| Nemoto, K | 1 |
| Fukuda, H | 1 |
| Hagiwara, T | 1 |
| Kurokawa, H | 1 |
| Miura, K | 1 |
| Tokudome, S | 1 |
| Murata, T | 1 |
| Kajiyama, M | 1 |
| Naito, Y | 1 |
| Kimura, S | 1 |
| Yoshizawa, M | 1 |
| Ohtake, K | 1 |
| Nakajima, T | 1 |
| Saku, T | 1 |
| Iida, A | 1 |
| Takagi, R | 1 |
| Hoshina, H | 1 |
| Ono, K | 1 |
| Kaji, M | 1 |
| Tsurumaki, H | 1 |
| Fukuda, J | 1 |
| Nagashima, K | 1 |
| Miyaura, Y | 1 |
| Hayatsu, M | 1 |
| Miyamoto, T | 1 |
| Ikeda, H | 1 |
| Kitamura, A | 1 |
| Uehara, M | 1 |
| Tobita, T | 1 |
| Ohba, S | 1 |
| Nonaka, M | 1 |
| Fujisawa, A | 1 |
| Inokuchi, T | 1 |
| Tsukuda, M | 1 |
| Yanoma, S | 1 |
| Sudo, K | 1 |
| Sawaki, S | 1 |
| Tanaka, J | 1 |
| Takaoka, T | 1 |
| Hosoda, H | 1 |
| Fujii, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Study of Toripalimab Monoclonal Antibody Combined With Gemcitabine/5--fluoropyrimidine in the Treatment of Advanced Cholangiocarcinoma[NCT03982680] | Phase 2 | 30 participants (Anticipated) | Interventional | 2019-07-13 | Recruiting | ||
| A Prospective, Single-arm Study of Simultaneous Modulated Accelerated Radiotherapy Combined With S-1/DDP for Elderly Esophageal Squamous Cell Carcinoma.[NCT02606916] | Phase 2 | 42 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tegafur and Mouth Neoplasms
| Article | Year |
|---|---|
[Reinforcement of warfarin action in a patient administered S-1].
Topics: Aged; Anticoagulants; Antimetabolites, Antineoplastic; Cardiomyopathy, Hypertrophic; Cerebral Infarc | 2015 |
12 trials available for tegafur and Mouth Neoplasms
| Article | Year |
|---|---|
[Clinical phase I trial of S-1 in the combination with DOC using super-selective intra-arterial infusion with oral cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Dose-Response Relationship, Drug; D | 2009 |
Phase II study of preoperative concurrent chemoradiation therapy with S-1 in patients with T4 oral squamous cell carcinoma.
Topics: Administration, Oral; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Combined Modality Therapy; | 2010 |
Preoperative concurrent chemotherapy with S-1 and radiotherapy for locally advanced squamous cell carcinoma of the oral cavity: phase I trial.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamo | 2010 |
Multicenter phase II trial of preoperative chemoradiotherapy with S-1 for locally advanced oral squamous cell carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemoradiotherapy; Drug Comb | 2013 |
Phase II study of a novel oral formation of 5-fluorouracil in combination with low-dose cisplatin as preoperative chemotherapy of oral squamous cell carcinoma.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2005 |
[Clinical trial of chemotherapy identified according to chemosensitivity assay for oral cancer patients with unresectable recurrent lesions].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration Schedu | 2006 |
[Phase I study of concurrent radiotherapy with S-1 for oral squamous cell carcinoma].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modality Therapy; D | 2006 |
[Preoperative chemotherapy with S-1 and low-dose cisplatin for oral squamous cell carcinoma].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy | 2006 |
Multi-institutional phase II trial of S-1 in patients with oral squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Dose-Response Relat | 2008 |
Clinical trials with oral Futraful (INN: Tegafur) in cancer of the head and neck.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Adenoid Cystic; Car | 1981 |
[Multiple cooperative study of UFT-adjuvant chemotherapy for malignant tumor in the jaw and oral cavities. The Oral Surgery Malignant Tumor Research Association in Kanto Kohshinetsu District].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carc | 1994 |
[Evaluation of neo-adjuvant chemotherapy for oral squamous cell carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; | 1997 |
48 other studies available for tegafur and Mouth Neoplasms
| Article | Year |
|---|---|
Efficacy of adjuvant chemotherapy with S-1 in stage II oral squamous cell carcinoma patients: A comparative study using the propensity score matching method.
Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Combinati | 2020 |
The Immunological Impact of Chemotherapy on the Tumor Microenvironment of Oral Squamous Cell Carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; B7-H1 Antigen; Carcinoma, Squamous Cell; Case | 2017 |
The Impact of Metronomic Adjuvant Chemotherapy in Patients with Advanced Oral Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Case-Control Studies; Chem | 2018 |
ASO Author Reflections: Tegafur-Uracil in Advanced Oral Cancer.
Topics: Chemotherapy, Adjuvant; Humans; Leucovorin; Mouth Neoplasms; Tegafur | 2018 |
Long-term efficacy and toxicity of concurrent chemoradiotherapy with nedaplatin and S-1 for head and neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; D | 2019 |
[Clinicopathological Evaluation of Preoperative Chemotherapy Containing S-1 as a Treatment for Patients with Oral Squamous Cell Carcinoma during Waiting Time for Surgery].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Combinations; Humans; | 2019 |
Histopathological changes in tumor budding between biopsy and resected specimens from patients treated with preoperative S-1 chemotherapy for oral cancer.
Topics: Antimetabolites, Antineoplastic; Biopsy; Carcinoma, Squamous Cell; Drug Combinations; Humans; Mouth | 2019 |
Efficacy of schedule-dependent metronomic S-1 chemotherapy in human oral squamous cell carcinoma cells.
Topics: Administration, Metronomic; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carc | 2013 |
Decorin in human oral cancer: a promising predictive biomarker of S-1 neoadjuvant chemosensitivity.
Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Biomarkers, Tumor; Biopsy; Cell Line, Tumor | 2015 |
[Indication of alternate-day treatment with S-1 in patients with oral cancer].
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Drug Comb | 2015 |
[Two cases of giant metastatic cervical lymphnode from oral cancer responding to concurrent chemoradiotherapy with S-1].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug C | 2008 |
Effects of cepharanthine alone and in combination with fluoropyrimidine anticancer agent, S-1, on tumor growth of human oral squamous cell carcinoma xenografts in nude mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzylisoquinolines; Blotting, W | 2009 |
Clinical relevance of thymidylate synthase (TS) activity for S-1-based chemotherapy in squamous cell carcinoma of the oral cavity.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Drug Admi | 2010 |
The effect of neoadjuvant therapy on the 5-fluorouracil metabolic and relative enzymes of oral squamous cell carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcin | 2009 |
S-1 mediates the inhibition of lymph node metastasis in oral cancer cells.
Topics: Animals; Antimetabolites, Antineoplastic; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tu | 2009 |
[Immunohistochemical and clinicopathological study of thymidylate synthase, dihydropyrimidine dehydrogenase, and orotate phosphoribosyl transferase expression in oral cancer patients responding to UFT].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation | 2010 |
Effects of lentinan alone and in combination with fluoropyrimidine anticancer agent on growth of human oral squamous cell carcinoma in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Line, Tumor; | 2010 |
[Evaluation of combination chemotherapy with oral S-1 administration followed by docetaxel by superselective intra-arterial infusion for patients with oral squamous cell carcinomas].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2011 |
Efficacy and toxicity of S-1 plus cisplatin combination neoadjuvant chemotherapy in patients with oral cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cisplatin; Dihydrouracil Dehydrogenase | 2011 |
[Clinical analyses of oral squamous cell carcinoma patients showing a complete response to chemotherapy with S-1 alone].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Drug Combination | 2011 |
[The clinical effect of combination therapy for oral cancer with S-1, superselective intra-arterial chemotherapy, and radiation therapy].
Topics: Administration, Oral; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combi | 2011 |
Histopathological changes in parotid and submandibular glands of patients treated with preoperative chemoradiation therapy for oral cancer.
Topics: Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemoradiotherapy; Drug Combinations; Female; | 2012 |
[Successful outcome from treatment modality with low-dose S-1 for three oldest old patients with advanced oral cancer].
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Drug Combinations; Female; Humans; Mouth Neoplas | 2012 |
Thymidylate synthase and dihydropyrimidine dehydrogenase expression in oral squamous cell carcinoma: an immunohistochemical and clinicopathologic study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 2002 |
[Neoadjuvant chemotherapy with nedaplatin and UFT for oral squamous cell carcinomas].
Topics: Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamo | 2003 |
Predictive value of immunohistochemical thymidylate synthase expression for histological response to Tegafur/Uracil (UFT) in oral squamous cell carcinoma.
Topics: Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell | 2003 |
[An advanced case of squamous cell carcinoma in the left buccal mucosa, upper gingiva, and maxillary sinus (T4N0M0) showing a complete response to chemotherapy with TS-1].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Drug Administrat | 2004 |
Combined effects of the oral fluoropyrimidine anticancer agent, S-1 and radiation on human oral cancer cells.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Squamous Cell; Cell Survival; Combin | 2004 |
[Preoperative chemotherapy with TS-1 and low dose cisplatin for oral squamous cell carcinoma patients--a preliminary study].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 2005 |
S-1, an oral fluoropyrimidine anti-cancer agent, enhanced radiosensitivity in a human oral cancer cell line in vivo and in vitro: involvement possibility of inhibition of survival signal, Akt/PKB.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Drug Combinations; Enzyme Activation; | 2005 |
Thymidylate synthase expression in oral squamous cell carcinoma predicts response to S-1.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Dihydrouracil Dehydrogenase (NADP); Drug C | 2006 |
Retrospective analysis on prognostic impact of adjuvant chemotherapy in the patients with advanced and resectable oral squamous cell carcinoma.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2006 |
S-1 inhibits tumorigenicity and angiogenesis of human oral squamous cell carcinoma cells by suppressing expression of phosphorylated Akt, vascular endothelial growth factor and fibroblast growth factor-2.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Combinati | 2007 |
Targeted intra-arterial carboplatin chemoradiotherapy and tegafur/uracil for oral and oropharyngeal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carboplatin; | 2006 |
[The relationship between gene expression of Bcl-2 and Bax and the therapeutic effect in oral cancer patients].
Topics: Antineoplastic Combined Chemotherapy Protocols; bcl-2-Associated X Protein; Gene Expression; Genes, | 2006 |
[Nedaplatin (NDP)-combination therapy (NDP/5-FU,NDP/S-1) for oral cancer].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2007 |
[Clinical evaluation of palliative chemotherapy with S-1 for oral cancer patients].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modalit | 2007 |
[A case of advanced oral squamous cell carcinoma responding to concurrent radiotherapy with S-1].
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Adm | 2007 |
[A case of oral squamous cell carcinoma responding to S-1].
Topics: Administration, Oral; Aged; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Biomarkers, Tumor; | 2007 |
Investigation of optimal schedule of concurrent radiotherapy with S-1 for oral squamous cell carcinoma.
Topics: Aged; Animals; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Squamous Cell; Combined Modali | 2007 |
[Evaluation of combination chemotherapy with S-1 and docetaxel for patients with oral squamous cell carcinomas].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P | 2007 |
[Clinical study related to the concentration of Futraful suppository in organs].
Topics: Female; Fluorouracil; Humans; Jaw Neoplasms; Male; Mouth Neoplasms; Suppositories; Tegafur; Tissue D | 1983 |
Carboplatin plus ftorafur as a palliative treatment in locally advanced cancer of the oral cavity and lip.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Drug Administration Schedu | 1994 |
Effects of the anticancer drug cocktail "UFT" on metastatic potentials of squamous cell carcinoma (O-1N) in a hamster model.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols | 1998 |
[5-FU concentration in the serum and the tumor tissue after administration of UFT 200 mg/day to patients over 80 years of age with oral cancer].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Proto | 2000 |
[A case of squamous cell carcinoma of the oral floor showing a complete response to oral administration of UFT].
Topics: Administration, Oral; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Combinations; Huma | 2001 |
[Combination effect of UFT and gamma-irradiation against nude mice transplanted KB cells].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Ga | 1989 |
[Preoperative chemotherapy for head and neck cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Fluorouracil; Head and Neck Ne | 1985 |