tegafur has been researched along with Leukemia L 1210 in 19 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " The dosage of the oral clinical use for human cancer of 5-FU, HCFU, 5'-DFUR and UFT as tegafur (FT) is 200-300mg/d, 600mg/d, 800-1,200mg/d and 300-600mg/d respectively." | 1.31 | Plasma, intestine and tumor levels of 5-fluorouracil in mice bearing L1210 ascites tumor following oral administration of 5-fluorouracil, UFT (mixed compound of tegafur and uracil), carmofur and 5'-deoxy-5-fluorouridine. ( Higashigawa, M; Kagawa, Y; Kakito, H; Kawasaki, H; Kojima, M; Ohkubo, T; Ooi, A; Sakurai, M, 2001) |
| " The bioavailability of UK-21 given p." | 1.28 | Antitumor activity of two novel low immunosuppressive fluoropyrimidines UK-21 and UK-25. ( Kato, T; Kitaichi, K; Koda, A; Mori, H; Sakamoto, O, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (68.42) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, AJ | 1 |
| Benjamin, RS | 1 |
| Rao, PN | 1 |
| Loo, TL | 2 |
| Holshouser, MH | 1 |
| Shipp, AM | 1 |
| Ferguson, PW | 1 |
| Ishitsuka, H | 1 |
| Miwa, M | 1 |
| Takemoto, K | 1 |
| Fukuoka, K | 1 |
| Itoga, A | 1 |
| Maruyama, HB | 1 |
| Schultze, B | 1 |
| Jellinghaus, W | 1 |
| Weis, G | 1 |
| Müller, V | 1 |
| Maurer, W | 1 |
| Grossie, VB | 1 |
| Rosenblum, MG | 1 |
| Kagawa, Y | 3 |
| Ohkubo, T | 3 |
| Higashigawa, M | 3 |
| Ido, M | 1 |
| Kakito, H | 3 |
| Inagaki, S | 2 |
| Kojima, M | 2 |
| Ooi, K | 2 |
| Sakurai, M | 3 |
| Sumida, K | 1 |
| Zhuk, R | 1 |
| Ooi, A | 1 |
| Kawasaki, H | 1 |
| Carter, SK | 1 |
| Slavik, M | 1 |
| van Putten, LM | 1 |
| Lelieveld, P | 1 |
| Pantarotto, C | 1 |
| Salmona, M | 1 |
| Spreafico, F | 1 |
| Garibjanian, BT | 1 |
| Johnson, RK | 1 |
| Kline, I | 1 |
| Vadlamudi, S | 1 |
| Gang, M | 1 |
| Venditti, JM | 1 |
| Goldin, A | 1 |
| Sakamoto, O | 1 |
| Mori, H | 1 |
| Kitaichi, K | 1 |
| Koda, A | 1 |
| Kato, T | 2 |
| Novotný, L | 1 |
| Vachálková, A | 1 |
| Uehara, N | 1 |
| Baba, H | 1 |
| Nitta, K | 1 |
| Kunimoto, T | 1 |
| Takeuchi, M | 1 |
| Sasaki, T | 1 |
| Tanaka, T | 1 |
| Ota, K | 1 |
| Furue, H | 1 |
| Niitani, H | 1 |
| Kurihara, M | 1 |
| Hasegawa, K | 1 |
| Nakao, I | 1 |
| Tsukagoshi, S | 1 |
| Fujita, H | 1 |
| Hayakawa, M | 1 |
| Morise, K | 1 |
| Oka, Y | 1 |
| Saito, H | 1 |
| Suga, S | 1 |
| Kimura, K | 1 |
| Iwase, H | 1 |
| Ina, K | 1 |
| Takada, N | 1 |
| Matsuoka, S | 1 |
| Matsuura, T | 1 |
| Yamada, K | 1 |
| Horiuchi, T | 1 |
| Hashizume, H | 1 |
1 review available for tegafur and Leukemia L 1210
| Article | Year |
|---|---|
Investigational drugs under study by the United States National Cancer Institute.
Topics: Acrylates; Alkylating Agents; Ancitabine; Animals; Antibiotics, Antineoplastic; Antimetabolites, Ant | 1976 |
18 other studies available for tegafur and Leukemia L 1210
| Article | Year |
|---|---|
Synthesis and biological activities of ftorafur metabolites. 3'- and 4'-hydroxyftorafur.
Topics: Animals; Antineoplastic Agents; Cell Division; Fluorouracil; HeLa Cells; Humans; Hydroxylation; Leuk | 1979 |
Synthesis and antitumor activity of a series of ftorafur analogues: the effect of varying electronegativity at the 1'-position.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Female; Fluorouracil; Leukemia L1210; Leukemia P388 | 1985 |
Role of uridine phosphorylase for antitumor activity of 5'-deoxy-5-fluorouridine.
Topics: Animals; Biotransformation; Floxuridine; Fluorouracil; Leukemia L1210; Male; Mice; Pentosyltransfera | 1980 |
Comparing cell kinetic studies of the effect of ftorafur and 5-fluorouracil on the L 1210 ascites tumor.
Topics: Animals; Cell Division; Female; Fluorouracil; Kinetics; Leukemia L1210; Mice; Mitosis; Neoplasm Tran | 1981 |
Combination chemotherapy with cyclophosphamide and ftorafur against advanced L1210 murine leukemia.
Topics: Animals; Cyclophosphamide; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; | 1982 |
Effects of UFT (mixed compound of tegafur and uracil) on cell kinetics and inhibition of thymidylate synthase in L1210 ascites tumor.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Deoxyuridine; Drug Combinations; Leukemia L1210; Male; M | 1995 |
Effects of 5-fluorouracil and a combination of tegafur and uracil (UFT) on nucleotide metabolism in L1210 ascites tumor.
Topics: Animals; Deoxyribonucleotides; Fluorouracil; Injections, Intraperitoneal; Leukemia L1210; Male; Mice | 1993 |
Structure-activity relationship in Ftorafur (Tegafur) and related 5-FU prodrugs.
Topics: Animals; Antimetabolites, Antineoplastic; Fluorouracil; Humans; Indicators and Reagents; Leukemia L1 | 1998 |
Plasma, intestine and tumor levels of 5-fluorouracil in mice bearing L1210 ascites tumor following oral administration of 5-fluorouracil, UFT (mixed compound of tegafur and uracil), carmofur and 5'-deoxy-5-fluorouridine.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Drug Combinations; F | 2001 |
Ftorafur: a self-limiting source of 5-fluorouracil?
Topics: Animals; Biotransformation; Fluorouracil; Hematopoietic Stem Cells; Lethal Dose 50; Leukemia L1210; | 1979 |
Comparison of 5-fluorouracil and ftorafur. II. Therapeutic response and development of resistance in murine tumors.
Topics: Animals; Carcinoma; Cell Line; Drug Resistance; Drug Therapy, Combination; Female; Fluorouracil; Leu | 1976 |
Antitumor activity of two novel low immunosuppressive fluoropyrimidines UK-21 and UK-25.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Fluorouracil; Glycine; Leukemia L | 1992 |
Some electrochemical characteristics of synthetic analogs of nucleic acid components. III. Derivatives of 5-fluorouridine. An attempt to find correlation between some of their characteristics.
Topics: Animals; Leukemia L1210; Nucleic Acids; Polarography; Tegafur; Thioctic Acid; Tumor Cells, Cultured; | 1991 |
The therapeutic effects of orally administered 5'-deoxy-5-fluorouridine, 1-(2-tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil on experimental murine tumors.
Topics: Animals; Antineoplastic Agents; Floxuridine; Fluorouracil; Leukemia L1210; Mice; Neoplasms, Experime | 1985 |
[Effects of derivatives of Ara-C, 5-fluorouracil and nitrosourea against intracerebral implanted L1210 leukemia].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; | 1987 |
[FO-152].
Topics: Absorption; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Dogs; Drug Evaluation; Female | 1987 |
[Combination chemotherapy of UFT, etoposide and CDDP in advanced gastric cancer].
Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; | 1987 |
[UFT, UFTM, and UFTM-Dpc treatment of gastric cancer].
Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Humans; Leukemia L1210; Male; Mice; M | 1985 |