Page last updated: 2024-11-04

tegafur and Glioma

tegafur has been researched along with Glioma in 9 studies

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Controlled, prospective, randomized studies were performed to evaluate the effects of 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3- (2-chloroethyl)-3-nitrosourea hydrochloride (ACNU) and ACNU plus tegafur as additions to radiotherapy for the treatment of malignant gliomas."9.05[Evaluation of ACNU alone and combined with tegafur as additions to radiotherapy of the treatment of malignant gliomas--a cooperative clinical trial]. ( Abe, H; Kitamura, K; Matsutani, M; Miwa, T; Nomura, K; Suzuki, J; Takakura, K; Takeuchi, K; Tanaka, R; Ushio, Y, 1985)
" Conventional, external radiotherapy (180-200 cGy/5 fractions/week) using 60Co or a 10 MV linear accelerator was given in conjunction with chemotherapy of nimustine hydrochloride (ACNU) and tegafur (FT-207) in eight patients with gliomas."7.67[Radiochemotherapy-related changes in the brain parenchyma of glioma patients evaluated repeatedly by C15O2, C15O, 15O2, and 18F-fluorodeoxyglucose (FDG) PET]. ( Kowada, M; Mineura, K; Ogawa, T; Sasajima, T; Shishido, F; Suda, Y; Uemura, K, 1989)
"Controlled, prospective, randomized studies were performed to evaluate the effects of 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3- (2-chloroethyl)-3-nitrosourea hydrochloride (ACNU) and ACNU plus tegafur as additions to radiotherapy for the treatment of malignant gliomas."5.05[Evaluation of ACNU alone and combined with tegafur as additions to radiotherapy of the treatment of malignant gliomas--a cooperative clinical trial]. ( Abe, H; Kitamura, K; Matsutani, M; Miwa, T; Nomura, K; Suzuki, J; Takakura, K; Takeuchi, K; Tanaka, R; Ushio, Y, 1985)
" Conventional, external radiotherapy (180-200 cGy/5 fractions/week) using 60Co or a 10 MV linear accelerator was given in conjunction with chemotherapy of nimustine hydrochloride (ACNU) and tegafur (FT-207) in eight patients with gliomas."3.67[Radiochemotherapy-related changes in the brain parenchyma of glioma patients evaluated repeatedly by C15O2, C15O, 15O2, and 18F-fluorodeoxyglucose (FDG) PET]. ( Kowada, M; Mineura, K; Ogawa, T; Sasajima, T; Shishido, F; Suda, Y; Uemura, K, 1989)
"Haemocirculatory and metabolic changes in seemingly normal brain tissue following radiochemotherapy including nimustine hydrochloride (ACNU) and tegafur (FT) were analyzed using oxygen-15 and fluorine-18 positron emission tomography (PET) in seven patients with gliomas."3.67Early and late stage positron emission tomography (PET) studies on the haemocirculation and metabolism of seemingly normal brain tissue in patients with gliomas following radiochemotherapy. ( Kowada, M; Mineura, K; Ogawa, T; Shishido, F; Suda, Y; Uemura, K; Yasuda, T, 1988)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's2 (22.22)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tsuchida, T1
Watanabe, E1
Nakayama, H1
Sasaki, A1
Nakamura, S1
Sasaki, M1
Fujiwara, T1
Nemoto, S1
Fujiwara, K1
Yanagibashi, K1
Hayakawa, I1
Nomura, K2
Harada, K1
Okamoto, H1
Kiya, K1
Fujioka, Y1
Uozumi, T1
Kodama, Y1
Mori, T1
Fukawa, O1
Sato, T1
Hori, S1
Tomura, N1
Kato, T1
Ogawa, T3
Kanno, I1
Shishido, F3
Inugami, A1
Fujita, H1
Higano, S1
Murakami, M1
Uemura, K3
Wakisaka, S2
Shimauchi, M2
Kaji, Y2
Nonaka, A2
Kinoshita, K2
Mineura, K2
Suda, Y2
Sasajima, T1
Kowada, M2
Ushio, Y1
Abe, H1
Suzuki, J1
Tanaka, R1
Kitamura, K1
Miwa, T1
Matsutani, M1
Takeuchi, K1
Takakura, K1
Maruoka, N1
Moriyama, T1
Oyama, H1
Goya, T1
Kodama, T1
Yasuda, T1

Trials

1 trial available for tegafur and Glioma

ArticleYear
[Evaluation of ACNU alone and combined with tegafur as additions to radiotherapy of the treatment of malignant gliomas--a cooperative clinical trial].
    No to shinkei = Brain and nerve, 1985, Volume: 37, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Cli

1985

Other Studies

8 other studies available for tegafur and Glioma

ArticleYear
[FAR therapy in brain tumors--FT207-vitamin A-Radiation therapy (author's transl)].
    Neurologia medico-chirurgica, 1980, Volume: 20, Issue:5

    Topics: Adolescent; Adult; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Drug Therapy, Combination;

1980
[Pharmacokinetics study of UFT in malignant brain tumor patients].
    Neurologia medico-chirurgica, 1983, Volume: 23, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

1983
[Regression of a recurrent malignant glioma by combined chemoradiotherapy utilizing carboquone, FT-207 and telecobalt--report of a case (author's transl)].
    No shinkei geka. Neurological surgery, 1977, Volume: 5, Issue:8

    Topics: Azirines; Brain Neoplasms; Carbazilquinone; Cobalt Radioisotopes; Drug Therapy, Combination; Fluorou

1977
[The changes of cerebral blood flow and metabolism of normal brain tissue after surgery, radiation, and chemotherapy in brain tumor patients: evaluated by position emission tomography].
    No to shinkei = Brain and nerve, 1990, Volume: 42, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Cerebrova

1990
Acute phenytoin intoxication associated with the antineoplastic agent UFT.
    Fukuoka igaku zasshi = Hukuoka acta medica, 1990, Volume: 81, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; D

1990
[Radiochemotherapy-related changes in the brain parenchyma of glioma patients evaluated repeatedly by C15O2, C15O, 15O2, and 18F-fluorodeoxyglucose (FDG) PET].
    No shinkei geka. Neurological surgery, 1989, Volume: 17, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Agents; Brain; Brain Neoplasms; Carbon Radioisotopes; Cerebrovascu

1989
[AUFRAP therapy: combined modality treatment of malignant gliomas with intraarterial infusion of ACNU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8 Pt 2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carotid Artery, Internal; Co

1988
Early and late stage positron emission tomography (PET) studies on the haemocirculation and metabolism of seemingly normal brain tissue in patients with gliomas following radiochemotherapy.
    Acta neurochirurgica, 1988, Volume: 93, Issue:3-4

    Topics: Adolescent; Adult; Brain; Brain Neoplasms; Cerebrovascular Circulation; Child; Combined Modality The

1988