tegafur has been researched along with Complication, Postoperative in 27 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the efficacy of preoperative radiation therapy for resectable rectal adenocarcinoma (T3-T4) when delivered in combination with chemotherapy (oral tegafur-uracil modulated with leucovorin)." | 9.10 | Efficacy of preoperative radiation therapy for resectable rectal adenocarcinoma when combined with oral tegafur-uracil modulated with leucovorin: results from a phase II study. ( Batlle, JF; Carpeño, Jde C; García, AG; Grande, AG; Juberías, AM; Olivar, LM; Piñeiro, EH; Sánchez Santos, ME; Uzcudun, AE; Velasco, JC, 2002) |
| "Preoperative tegafur suppositories are associated with low toxicity and may lead to anal sphincter-sparing surgery with acceptable postoperative complications and favorable local and distal control." | 5.12 | Preoperative tegafur suppositories for resectable rectal cancer: phase II trial. ( Hamada, K; Izumi, M; Kashiwabara, K; Kawate, S; Nakamura, S; Ogawa, T; Ohwada, S; Sato, Y, 2006) |
| "The aim of this study was to evaluate the efficacy of preoperative radiation therapy for resectable rectal adenocarcinoma (T3-T4) when delivered in combination with chemotherapy (oral tegafur-uracil modulated with leucovorin)." | 5.10 | Efficacy of preoperative radiation therapy for resectable rectal adenocarcinoma when combined with oral tegafur-uracil modulated with leucovorin: results from a phase II study. ( Batlle, JF; Carpeño, Jde C; García, AG; Grande, AG; Juberías, AM; Olivar, LM; Piñeiro, EH; Sánchez Santos, ME; Uzcudun, AE; Velasco, JC, 2002) |
| "Locally advanced gastric cancer with extensive regional and/or para-aortic lymph node (PAN) metastases is typically unresectable and associated with poor outcomes." | 2.79 | Neoadjuvant chemotherapy with S-1 and cisplatin followed by D2 gastrectomy with para-aortic lymph node dissection for gastric cancer with extensive lymph node metastasis. ( Fukushima, N; Mizusawa, J; Nashimoto, A; Sasako, M; Tanaka, Y; Tsuburaya, A, 2014) |
| "Postoperative complications were identified in 18 patients and the overall morbidity rate was 26." | 2.79 | Low creatinine clearance is a risk factor for D2 gastrectomy after neoadjuvant chemotherapy. ( Aoyama, T; Cho, H; Hayashi, T; Ito, Y; Miyashita, Y; Morita, S; Nishikawa, K; Ogata, T; Sakamoto, J; Tanabe, K; Tsuburaya, A; Yoshikawa, T, 2014) |
| " Furthermore, the survival was elevated in proportion to the increase of total dosage of futraful." | 2.65 | [Effect of postoperative long-term chemotherapy of stomach cancer using mitomycin C and futraful--the secondary study (1)]. ( Abe, O; Akiyama, H; Hattori, T; Hayasaka, A; Inokuchi, K; Inoue, K; Ito, I; Kasai, Y; Kikuchi, K; Kondo, T; Muto, T; Nakajima, T; Sugie, S; Taguchi, T, 1982) |
| "Sarcopenia is related to poor survival in gastric cancer patients and appears to be a significant negative prognostic factor in patients with gastric cancer who underwent curative resection." | 1.48 | Long-Term Outcomes of Gastric Cancer Patients with Preoperative Sarcopenia. ( Aoyama, T; Bando, E; Inano, T; Kawamura, T; Makuuchi, R; Tanizawa, Y; Terashima, M; Tokunaga, M; Yasui, H, 2018) |
| "Patients with pathological stage II/III gastric cancer undergoing LG with D2 lymphadenectomy (LG group: n = 74) were matched 1:1 with patients selected from 214 similar patients undergoing OG (OG group: n = 74), identically matching gender, age, pathological stage, and type of gastrectomy, and comparing AC initiation timing between the two groups." | 1.46 | Timing of initiation of adjuvant chemotherapy for gastric cancer: A case-matched comparison study of laparoscopic vs. open surgery. ( Kaito, A; Kinoshita, T; Nishida, T; Shibasaki, H; Shitara, K, 2017) |
| "5-Fluorouracil-based chemotherapy is considered to be a radiosensitizer; however, conventional short-course radiotherapy combined with chemotherapy is generally thought to not be feasible because of the prevalence of side effects." | 1.42 | Feasibility of modified short-course radiotherapy combined with a chemoradiosensitizer for T3 rectal cancer. ( Beppu, N; Doi, H; Kakuno, A; Kamikonya, N; Matsubara, N; Tomita, N; Yamanaka, N; Yanagi, H, 2015) |
| "Prevention of postoperative complication is needed to enable early initiation." | 1.39 | Early initiation of adjuvant chemotherapy improves survival of patients with pancreatic carcinoma after surgical resection. ( Hashimoto, Y; Kondo, N; Murakami, Y; Nakagawa, N; Sasaki, H; Sudo, T; Sueda, T; Uemura, K, 2013) |
| " Two cycles of intraperitoneal chemotherapy with docetaxel combined with S-1, were administrated and gastrectomy with lymph node dissection was performed in cases without macroscopic PC at post-NIPS staging laparoscopy." | 1.38 | Intraperitoneal docetaxel combined with S-1 for advanced gastric cancer with peritoneal dissemination. ( Doki, Y; Fujiwara, Y; Kurokawa, Y; Miyata, H; Mori, M; Nakajima, K; Takiguchi, S; Yamasaki, M, 2012) |
| "The prognosis of gastric cancer with para-aortic lymph node (PAN) metastasis is poor." | 1.38 | Efficacy of pre-operative chemotherapy with docetaxel, cisplatin, and S-1 (DCS therapy) and curative resection for gastric cancer with pathologically positive para-aortic lymph nodes. ( Fujimura, T; Fujita, H; Fushida, S; Hayashi, H; Kinoshita, J; Kitagawa, H; Makino, I; Nakagawara, H; Nakamura, K; Ninomiya, I; Ohta, T; Oyama, K; Tajima, H; Takamura, H; Tani, T, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.41) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (22.22) | 29.6817 |
| 2010's | 17 (62.96) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Watanabe, H | 1 |
| Hayashi, T | 2 |
| Komori, K | 1 |
| Hara, K | 1 |
| Maezawa, Y | 2 |
| Kano, K | 2 |
| Shimoda, Y | 1 |
| Fujikawa, H | 1 |
| Aoyama, T | 4 |
| Yamada, T | 2 |
| Yamamoto, N | 1 |
| Cho, H | 3 |
| Ito, H | 1 |
| Shiozawa, M | 1 |
| Yukawa, N | 2 |
| Morinaga, S | 1 |
| Yoshikawa, T | 2 |
| Rino, Y | 2 |
| Masuda, M | 2 |
| Ogata, T | 2 |
| Oshima, T | 2 |
| Tsuchida, K | 1 |
| Sato, T | 1 |
| Atsumi, Y | 1 |
| Kazama, K | 1 |
| Numata, M | 1 |
| Tamagawa, H | 1 |
| Murakami, H | 1 |
| Saeki, H | 1 |
| Yamamoto, Y | 1 |
| Yamashita, K | 1 |
| Kurokawa, Y | 2 |
| Yamamoto, K | 1 |
| Hirota, M | 1 |
| Kawabata, R | 1 |
| Mikami, J | 1 |
| Masuzawa, T | 1 |
| Takiguchi, S | 2 |
| Mori, M | 2 |
| Doki, Y | 2 |
| Zhao, Q | 1 |
| Li, Y | 1 |
| Huang, J | 1 |
| Fan, L | 1 |
| Tan, B | 1 |
| Tian, Y | 1 |
| Yang, P | 1 |
| Jiao, Z | 1 |
| Zhao, X | 1 |
| Zhang, Z | 1 |
| Wang, D | 1 |
| Liu, Y | 1 |
| Kawamura, T | 1 |
| Makuuchi, R | 1 |
| Tokunaga, M | 1 |
| Tanizawa, Y | 1 |
| Bando, E | 1 |
| Yasui, H | 1 |
| Inano, T | 1 |
| Terashima, M | 1 |
| Kinoshita, O | 1 |
| Nakanishi, M | 1 |
| Ishimoto, T | 1 |
| Murayama, Y | 1 |
| Yasukawa, S | 1 |
| Kuriu, Y | 1 |
| Masuzawa, N | 1 |
| Kishimoto, M | 1 |
| Konishi, E | 1 |
| Yanagisawa, A | 1 |
| Otsuji, E | 1 |
| Tsuburaya, A | 2 |
| Mizusawa, J | 1 |
| Tanaka, Y | 1 |
| Fukushima, N | 1 |
| Nashimoto, A | 1 |
| Sasako, M | 1 |
| Tanabe, K | 1 |
| Nishikawa, K | 1 |
| Ito, Y | 1 |
| Morita, S | 1 |
| Miyashita, Y | 1 |
| Sakamoto, J | 1 |
| Beppu, N | 2 |
| Matsubara, N | 2 |
| Noda, M | 1 |
| Yamano, T | 1 |
| Doi, H | 2 |
| Kamikonya, N | 2 |
| Yamanaka, N | 2 |
| Yanagi, H | 2 |
| Tomita, N | 2 |
| Sadahiro, S | 2 |
| Suzuki, T | 2 |
| Tanaka, A | 2 |
| Okada, K | 2 |
| Saito, G | 1 |
| Kamijo, A | 2 |
| Akiba, T | 2 |
| Kawada, S | 1 |
| Feng, D | 1 |
| Leong, M | 1 |
| Li, T | 2 |
| Chen, L | 1 |
| Kakuno, A | 1 |
| Satoi, S | 1 |
| Yanagimoto, H | 1 |
| Yamamoto, T | 1 |
| Ohe, C | 1 |
| Miyasaka, C | 1 |
| Uemura, Y | 1 |
| Hirooka, S | 1 |
| Yamaki, S | 1 |
| Ryota, H | 1 |
| Michiura, T | 1 |
| Inoue, K | 2 |
| Matsui, Y | 1 |
| Tanigawa, N | 1 |
| Kon, M | 1 |
| Kaito, A | 1 |
| Kinoshita, T | 1 |
| Shitara, K | 1 |
| Shibasaki, H | 1 |
| Nishida, T | 1 |
| Park, IJ | 1 |
| Choi, GS | 1 |
| Lim, KH | 1 |
| Kang, BM | 1 |
| Jun, SH | 1 |
| Fujiwara, Y | 1 |
| Nakajima, K | 1 |
| Miyata, H | 1 |
| Yamasaki, M | 1 |
| Oyama, K | 1 |
| Fushida, S | 1 |
| Kinoshita, J | 1 |
| Makino, I | 1 |
| Nakamura, K | 1 |
| Hayashi, H | 1 |
| Nakagawara, H | 1 |
| Tajima, H | 1 |
| Fujita, H | 1 |
| Takamura, H | 1 |
| Ninomiya, I | 1 |
| Kitagawa, H | 1 |
| Tani, T | 1 |
| Fujimura, T | 1 |
| Ohta, T | 2 |
| Murayama, C | 1 |
| Nakayama, Y | 1 |
| Imamura, T | 1 |
| Kinugawa, K | 1 |
| Mohri, D | 1 |
| Shiga, T | 1 |
| Endo, M | 1 |
| Inaba, T | 1 |
| Maki, H | 1 |
| Hatano, M | 1 |
| Isayama, H | 1 |
| Yao, A | 1 |
| Hirata, Y | 1 |
| Koike, K | 1 |
| Nagai, R | 1 |
| Murakami, Y | 1 |
| Uemura, K | 1 |
| Sudo, T | 1 |
| Hashimoto, Y | 1 |
| Kondo, N | 1 |
| Nakagawa, N | 1 |
| Sasaki, H | 1 |
| Sueda, T | 1 |
| Uzcudun, AE | 1 |
| Batlle, JF | 1 |
| Velasco, JC | 1 |
| Sánchez Santos, ME | 1 |
| Carpeño, Jde C | 1 |
| Grande, AG | 1 |
| Juberías, AM | 1 |
| Piñeiro, EH | 1 |
| Olivar, LM | 1 |
| García, AG | 1 |
| Motoyama, H | 1 |
| Funakoshi, K | 1 |
| Akiyama, N | 1 |
| Inayoshi, J | 1 |
| Kozakai, I | 1 |
| Arai, F | 1 |
| Kato, T | 1 |
| Takii, Y | 1 |
| Saito, Y | 1 |
| Ichinose, Y | 1 |
| Fukuyama, Y | 1 |
| Asoh, H | 1 |
| Ushijima, C | 1 |
| Okamoto, T | 1 |
| Ikeda, J | 1 |
| Okamoto, J | 1 |
| Sakai, M | 1 |
| Ohwada, S | 1 |
| Sato, Y | 1 |
| Izumi, M | 1 |
| Kashiwabara, K | 1 |
| Ogawa, T | 1 |
| Hamada, K | 1 |
| Kawate, S | 1 |
| Nakamura, S | 1 |
| Saikawa, Y | 1 |
| Kubota, T | 1 |
| Kumagai, K | 1 |
| Nakamura, R | 1 |
| Kumai, K | 1 |
| Shigematsu, N | 1 |
| Kubo, A | 1 |
| Kitajima, M | 1 |
| Kitagawa, Y | 1 |
| Kasai, Y | 1 |
| Inokuchi, K | 1 |
| Hattori, T | 1 |
| Taguchi, T | 1 |
| Kondo, T | 1 |
| Akiyama, H | 1 |
| Abe, O | 1 |
| Ito, I | 1 |
| Nakajima, T | 1 |
| Muto, T | 1 |
| Kikuchi, K | 1 |
| Sugie, S | 1 |
| Hayasaka, A | 1 |
| Imaoka, S | 1 |
| Sasaki, Y | 1 |
| Shibata, T | 1 |
| Fujita, M | 1 |
| Ishikawa, O | 1 |
| Ohigashi, H | 1 |
| Furukawa, H | 1 |
| Koyama, H | 1 |
| Iwanaga, T | 1 |
| Hirose, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Oral Nutritional Supplement on Nutritional Status and Clinical Outcome in Gastric Cancer Patients After Total Gastrectomy[NCT05823272] | 60 participants (Anticipated) | Interventional | 2023-05-05 | Not yet recruiting | |||
| Apatinib Plus XELOX Regime as Neoadjuvant Therapy in Locally Advanced Gastric Cancer Patients With Lymph Node Metastasis[NCT03229096] | Phase 2 | 35 participants (Anticipated) | Interventional | 2017-02-01 | Recruiting | ||
| A Phase I Study of S-1 in Combination With Radiotherapy in Locally Advanced or Recurrent Gastric Cancer[NCT01291407] | Phase 1 | 27 participants (Actual) | Interventional | 2010-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 trials available for tegafur and Complication, Postoperative
| Article | Year |
|---|---|
Short-term results of a phase II study of preoperative docetaxel/cisplatin/S-1 therapy for locally advanced gastric cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Dose-Response Relationsh | 2021 |
Short-term curative effect of S-1 plus oxaliplatin as perioperative chemotherapy for locally advanced gastric cancer: a prospective comparison study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Disease-Free Su | 2017 |
Neoadjuvant chemotherapy with S-1 and cisplatin followed by D2 gastrectomy with para-aortic lymph node dissection for gastric cancer with extensive lymph node metastasis.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adj | 2014 |
Low creatinine clearance is a risk factor for D2 gastrectomy after neoadjuvant chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Mod | 2014 |
Phase II study of preoperative concurrent chemoradiotherapy with S-1 plus bevacizumab for locally advanced resectable rectal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy | 2015 |
Phase I/II study of preoperative concurrent chemoradiotherapy with S-1 for locally advanced, resectable rectal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy; | 2011 |
Efficacy of preoperative radiation therapy for resectable rectal adenocarcinoma when combined with oral tegafur-uracil modulated with leucovorin: results from a phase II study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 2002 |
Induction chemoradiotherapy and surgical resection for selected stage IIIB non-small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplat | 2003 |
Preoperative tegafur suppositories for resectable rectal cancer: phase II trial.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Humans; Male; Middl | 2006 |
Phase II study of chemoradiotherapy with S-1 and low-dose cisplatin for inoperable advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; D | 2008 |
[Effect of postoperative long-term chemotherapy of stomach cancer using mitomycin C and futraful--the secondary study (1)].
Topics: Aged; Antibiotics, Antineoplastic; Blood Cell Count; Body Weight; Clinical Trials as Topic; Drug The | 1982 |
16 other studies available for tegafur and Complication, Postoperative
| Article | Year |
|---|---|
Impact of Postoperative Complications on Recurrence in Patients With Stage II/III Gastric Cancer Who Received Adjuvant Chemotherapy With S-1.
Topics: Chemotherapy, Adjuvant; Drug Combinations; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, L | 2020 |
Risk Factors for Poor Compliance with Adjuvant S-1 Chemotherapy for Gastric Cancer: A Multicenter Retrospective Study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant | 2017 |
Long-Term Outcomes of Gastric Cancer Patients with Preoperative Sarcopenia.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cause of Death; Chemotherapy, Adjuvant; Dr | 2018 |
[An appropriate distal resection margin for lower rectal cancer after preoperative chemoradiotherapy].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemor | 2013 |
The timing of surgery after preoperative short-course S-1 chemoradiotherapy with delayed surgery for T3 lower rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy; | 2014 |
Surgical outcomes in patients with locally advanced gastric cancer treated with S-1 and oxaliplatin as neoadjuvant chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva | 2015 |
Feasibility of modified short-course radiotherapy combined with a chemoradiosensitizer for T3 rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Chemora | 2015 |
Clinical outcomes of pancreatic ductal adenocarcinoma resection following neoadjuvant chemoradiation therapy vs. chemotherapy.
Topics: Adult; Aged; Ascites; Carcinoma, Pancreatic Ductal; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuv | 2017 |
Timing of initiation of adjuvant chemotherapy for gastric cancer: A case-matched comparison study of laparoscopic vs. open surgery.
Topics: Abdominal Abscess; Adult; Aged; Aged, 80 and over; Anastomotic Leak; Antineoplastic Combined Chemoth | 2017 |
Laparoscopic resection of extraperitoneal rectal cancer: a comparative analysis with open resection.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Mod | 2009 |
Intraperitoneal docetaxel combined with S-1 for advanced gastric cancer with peritoneal dissemination.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Ther | 2012 |
Efficacy of pre-operative chemotherapy with docetaxel, cisplatin, and S-1 (DCS therapy) and curative resection for gastric cancer with pathologically positive para-aortic lymph nodes.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Doce | 2012 |
A case of pancreatic cancer after heart transplantation.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Cholestasis, Extrahepatic; Combined Modality Therap | 2012 |
Early initiation of adjuvant chemotherapy improves survival of patients with pancreatic carcinoma after surgical resection.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva | 2013 |
[A case of multiple lung metastases from colon cancer after sigmoidectomy treated effectively by chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colon, Sigmoid; Drug Administration Sc | 2003 |
[Anticancer effect of UFT in intrahepatic recurrence with tumor embolus in the left portal vein after hepatectomy of hepatoma--a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Hepatectomy; Humans | 1988 |