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tegafur and Carcinoma 256, Walker

tegafur has been researched along with Carcinoma 256, Walker in 5 studies

Carcinoma 256, Walker: A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
" The antitumor activity of this compound was superior to those of 5-FU and 1-(2-tetrahydrofuryl)-5-fluorouracil (Tegafur, Ftorafur) in the treatment of transplantable tumors, not only 5-FU-sensitive tumors such as adenocarcinoma 755, lymphosarcoma LS-1, and plasmacytoma X5563, but also 5-FU-resistant tumors such as Lewis lung carcinoma and Walker carcinosarcoma 256."3.66Antitumor activity of methyl (5-fluoro-1H-2-oxo-4-pyrimidinyl beta-D-glucopyranosid)uronate against various experimental tumors. ( Arakawa, M; Inomata, T; Sasagawa, K; Shimizu, F; Shinkai, K, 1981)
" At the 1st hr after dosing the 5-FU level in the small intestine was close to, but that in other tissues was much lower than, the 5-FU level in the tumor of both types."1.26Tissue distribution of 5'-deoxy-5-fluorouridine and derived 5-fluorouracil in tumor-bearing mice and rats. ( Fukazawa, H; Hongu, Y; Ichihara, S; Shimizu, H; Suzuki, S, 1980)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yasumoto, M1
Yamawaki, I1
Marunaka, T1
Hashimoto, S1
Suzuki, S1
Hongu, Y1
Fukazawa, H1
Ichihara, S1
Shimizu, H1
Mattern, J1
Volm, M1
Wayss, K1
Weber, N1
Arakawa, M1
Shimizu, F1
Sasagawa, K1
Inomata, T1
Shinkai, K1
Kozhukhov, AN1
Meĭren, DV1
Gilev, AP1

Other Studies

5 other studies available for tegafur and Carcinoma 256, Walker

ArticleYear
Studies on antitumor agents, 2. Syntheses and antitumor activities of 1-(tetrahydro-2-furanyl)-5-fluorouracil and 1,3-bis(tetrahydro-2-furanyl)-5-fluorouracil.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:8

    Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Fluorouracil; Letha

1978
Tissue distribution of 5'-deoxy-5-fluorouridine and derived 5-fluorouracil in tumor-bearing mice and rats.
    Gan, 1980, Volume: 71, Issue:2

    Topics: Animals; Carcinoma 256, Walker; Female; Floxuridine; Fluorouracil; Male; Mice; Rats; Sarcoma 180; Te

1980
[Studies in vivo and in vitro on the influence of 5-fluorouracil and n'-(2'-furanidyl)-5-fluorouracil on the walker carcinosarcoma 256 in the rat (author's transl)].
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:6

    Topics: Animals; Carcinoma 256, Walker; Deoxyuridine; Dose-Response Relationship, Drug; Fluorouracil; Male;

1980
Antitumor activity of methyl (5-fluoro-1H-2-oxo-4-pyrimidinyl beta-D-glucopyranosid)uronate against various experimental tumors.
    Gan, 1981, Volume: 72, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma 256, Walker; Female; Fluorouracil; Lung Neoplas

1981
[Pharmacokinetics of ftorafur-2-14C in rats with Walker carcinosarcoma].
    Biulleten' eksperimental'noi biologii i meditsiny, 1977, Volume: 83, Issue:6

    Topics: Animals; Carcinoma 256, Walker; Fluorouracil; Male; Mice; Tegafur

1977