Page last updated: 2024-11-04

tegafur and Carcinoma, Anaplastic

tegafur has been researched along with Carcinoma, Anaplastic in 89 studies

Research Excerpts

ExcerptRelevanceReference
"With a view to improving treatment response and the quality of life of cancer patients, this study investigated the clinical efficacy of combining lentinan, a flavonoid compound with antitumor abilities, with traditional chemotherapy in individuals with esophageal carcinoma (EC), with a particular focus on its effect on immune function."9.16Combination therapy with lentinan improves outcomes in patients with esophageal carcinoma. ( Bi, Z; Gu, XM; Wang, JL; Zou, JW, 2012)
"This study evaluated long-term outcomes for patients who received adjuvant gemcitabine plus S-1 chemotherapy after resection for pancreatic carcinoma."9.16Long-term results of adjuvant gemcitabine plus S-1 chemotherapy after surgical resection for pancreatic carcinoma. ( Hashimoto, Y; Kondo, N; Murakami, Y; Nakagawa, N; Nakashima, A; Sudo, T; Sueda, T; Uemura, K, 2012)
"The authors conclude that epirubicin, cisplatin, and oral UFT plus leucovorin, a convenient regimen, has a significant activity and tolerable toxicities in patients with gastric carcinoma."9.09Phase II trial of epirubicin, cisplatin, oral uracil and tegafur, and leucovorin in patients with advanced gastric carcinoma. ( Hyun, JH; Jeen, YT; Kim, BS; Kim, CS; Kim, JS; Kim, YH; Mok, YJ; Shin, SW; Yoon, SY, 2001)
"This is an open-label, nonrandomized phase I trial to determine the safety and maximum tolerated dose of irinotecan with a fixed dose of UFT plus oral leucovorin in patients with advanced or metastatic colorectal cancer."9.09UFT/leucovorin plus weekly irinotecan in advanced or metastatic colorectal cancer. ( Hegewisch-Becker, S; Hossfeld, DK; Lipp, R; Schilling, G, 2000)
"The results of this study show that an all-oral regimen of tegafur and leucovorin can obtain biochemical modulation, with a significant response rate, in patients with advanced colorectal carcinoma."9.08Protracted treatment with tegafur and low dose oral leucovorin in patients with advanced colorectal carcinoma. ( Antón, I; Arcusa, A; Batiste-Alentorn, E; Boleda, M; Nogué, M; Saigí, E; Seguí, MA, 1998)
"Both the biochemical modulation and the continuous administration of 5-fluorouracil (5-FU) have achieved promising results in patients with gastric carcinoma."9.08Treatment of patients with advanced gastric carcinoma with the combination of etoposide plus oral tegafur modulated by uracil and leucovorin. A phase II study of the ONCOPAZ Cooperative Group. ( Belón, J; Blanco, E; Espinosa, E; Feliu, J; García-Alfonso, P; García-Girón, C; Garrido, P; Gómez-Navarro, J; González Barón, M; Ordónez, A; Zamora, P, 1996)
"A randomized study was performed in 35 centers in the Kinki area of Japan to determine the effectiveness of ftrorafur (FT) plus tamoxifen (TAM) compared with FT monotherapy in postoperative adjuvant therapy for breast cancer."9.08A randomized trial comparing ftorafur alone with ftorafur plus tamoxifen in postoperative adjuvant therapy for breast cancer. Kinki Area Research Group for Postoperative Adjuvant Therapy for Breast Cancer. ( Kosaki, G; Koyama, H; Nakao, K; Oshima, A; Sakai, K; Seno, T; Taguchi, T; Terasawa, T, 1996)
"We performed a randomized controlled study of postoperative adjuvant immunochemotherapy with Nocardia rubra cell wall skeleton (N-CWS) and Tegafur for gastric carcinoma between September 1979 and March 1983."9.06Randomized controlled study of postoperative adjuvant immunochemotherapy with Nocardia rubra cell wall skeleton (N-CWS) and Tegafur for gastric carcinoma. ( Iwasaki, Y; Kawasaki, T; Koyama, S; Osuga, T; Ozaki, A; Sakita, T; Soma, T; Suzuki, M; Tabuchi, T; Watanabe, A, 1986)
"In the current study, we have evaluated the clinical and immunological responses in patients with advanced pancreatic carcinoma who received dendritic cell (DC)-based immunotherapy in combination with gemcitabine and/or S-1."7.78Clinical and immunologic evaluation of dendritic cell-based immunotherapy in combination with gemcitabine and/or S-1 in patients with advanced pancreatic carcinoma. ( Homma, S; Imai, K; Kimura, Y; Koido, S; Okamoto, M; Shimamura, K; Shimodaira, S; Sunamura, M; Takahashi, H; Tomoda, T; Tsukada, J; Yonemitsu, Y, 2012)
"Adjuvant gemcitabine plus S-1 chemotherapy may be one of several factors contributing to improved outcomes after aggressive surgical resection of advanced biliary carcinoma in recent years."7.75Adjuvant gemcitabine plus S-1 chemotherapy improves survival after aggressive surgical resection for advanced biliary carcinoma. ( Hashimoto, Y; Hayashidani, Y; Murakami, Y; Nakamura, H; Nakashima, A; Sudo, T; Sueda, T; Uemura, K, 2009)
" In a previous study, the authors demonstrated that the combination of uracil and tegafur (UFT) with leucovorin (LV) was active and well tolerated in patients with advanced colorectal carcinoma (ACC)."7.69Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group. ( Colmenarejo, A; de Castro, J; de la Gándara, I; Espinosa, E; Espinosa, J; Feliu, J; Fernández, Y; García Girón, C; González Barón, M; Jalón, JI, 1997)
"Effects of N-(6-aminohexyl)-1-naphthalenesulfonamide (W-5) and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur, FT) and a mixture of FT and uracil (UFT) were determined in nude mice bearing human ovarian carcinoma (KF cells)."7.67Adjuvant effects of calmodulin antagonists on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur) and a mixture of ftorafur and uracil (UFT) in nude mice bearing human ovarian carcinomas. ( Iwano, I; Kikuchi, Y; Kita, T; Kizawa, I; Kuki, E; Miyauchi, M; Oomori, K, 1989)
"A multicenter randomized trial was performed comparing oral tegafur/gimeracil/oteracil (S-1) and uracil-tegafur/ leucovorin (UFT/LV) as adjuvant therapy for stage III colorectal cancer."5.22Tumor 5-FU-related mRNA Expression and Efficacy of Oral Fluoropyrimidines in Adjuvant Chemotherapy of Colorectal Cancer. ( Kaiho, T; Kobayashi, S; Koda, K; Kosugi, C; Maruyama, T; Matsubara, H; Miyauchi, H; Takiguchi, N, 2016)
"With a view to improving treatment response and the quality of life of cancer patients, this study investigated the clinical efficacy of combining lentinan, a flavonoid compound with antitumor abilities, with traditional chemotherapy in individuals with esophageal carcinoma (EC), with a particular focus on its effect on immune function."5.16Combination therapy with lentinan improves outcomes in patients with esophageal carcinoma. ( Bi, Z; Gu, XM; Wang, JL; Zou, JW, 2012)
"This study evaluated long-term outcomes for patients who received adjuvant gemcitabine plus S-1 chemotherapy after resection for pancreatic carcinoma."5.16Long-term results of adjuvant gemcitabine plus S-1 chemotherapy after surgical resection for pancreatic carcinoma. ( Hashimoto, Y; Kondo, N; Murakami, Y; Nakagawa, N; Nakashima, A; Sudo, T; Sueda, T; Uemura, K, 2012)
"The authors conclude that epirubicin, cisplatin, and oral UFT plus leucovorin, a convenient regimen, has a significant activity and tolerable toxicities in patients with gastric carcinoma."5.09Phase II trial of epirubicin, cisplatin, oral uracil and tegafur, and leucovorin in patients with advanced gastric carcinoma. ( Hyun, JH; Jeen, YT; Kim, BS; Kim, CS; Kim, JS; Kim, YH; Mok, YJ; Shin, SW; Yoon, SY, 2001)
"This is an open-label, nonrandomized phase I trial to determine the safety and maximum tolerated dose of irinotecan with a fixed dose of UFT plus oral leucovorin in patients with advanced or metastatic colorectal cancer."5.09UFT/leucovorin plus weekly irinotecan in advanced or metastatic colorectal cancer. ( Hegewisch-Becker, S; Hossfeld, DK; Lipp, R; Schilling, G, 2000)
"Both the biochemical modulation and the continuous administration of 5-fluorouracil (5-FU) have achieved promising results in patients with gastric carcinoma."5.08Treatment of patients with advanced gastric carcinoma with the combination of etoposide plus oral tegafur modulated by uracil and leucovorin. A phase II study of the ONCOPAZ Cooperative Group. ( Belón, J; Blanco, E; Espinosa, E; Feliu, J; García-Alfonso, P; García-Girón, C; Garrido, P; Gómez-Navarro, J; González Barón, M; Ordónez, A; Zamora, P, 1996)
"The results of this study show that an all-oral regimen of tegafur and leucovorin can obtain biochemical modulation, with a significant response rate, in patients with advanced colorectal carcinoma."5.08Protracted treatment with tegafur and low dose oral leucovorin in patients with advanced colorectal carcinoma. ( Antón, I; Arcusa, A; Batiste-Alentorn, E; Boleda, M; Nogué, M; Saigí, E; Seguí, MA, 1998)
"Thirty-nine patients with locally advanced or metastatic gastric carcinoma received oral UFT (tegafur and uracil) plus leucovorin."5.08A phase II trial. Oral UFT and leucovorin in patients with advanced gastric carcinoma. ( Kim, BS; Kim, JG; Kim, JS; Kim, YH; Park, YT; Shin, SW, 1997)
"The activity and toxicity of UFT (Tegafur and Uracil) in a 4:1 molar concentration, plus leucovorin (LV), were evaluated in the treatment of 45 patients with advanced, bidimensionally measurable metastatic colorectal carcinoma."5.08Phase II study of UFT plus leucovorin in colorectal cancer. ( Pazdur, R, 1997)
"A randomized study was performed in 35 centers in the Kinki area of Japan to determine the effectiveness of ftrorafur (FT) plus tamoxifen (TAM) compared with FT monotherapy in postoperative adjuvant therapy for breast cancer."5.08A randomized trial comparing ftorafur alone with ftorafur plus tamoxifen in postoperative adjuvant therapy for breast cancer. Kinki Area Research Group for Postoperative Adjuvant Therapy for Breast Cancer. ( Kosaki, G; Koyama, H; Nakao, K; Oshima, A; Sakai, K; Seno, T; Taguchi, T; Terasawa, T, 1996)
"We performed a randomized controlled study of postoperative adjuvant immunochemotherapy with Nocardia rubra cell wall skeleton (N-CWS) and Tegafur for gastric carcinoma between September 1979 and March 1983."5.06Randomized controlled study of postoperative adjuvant immunochemotherapy with Nocardia rubra cell wall skeleton (N-CWS) and Tegafur for gastric carcinoma. ( Iwasaki, Y; Kawasaki, T; Koyama, S; Osuga, T; Ozaki, A; Sakita, T; Soma, T; Suzuki, M; Tabuchi, T; Watanabe, A, 1986)
"We examined the completion rate, safety, and adverse events in patients with T2N0 glottic carcinoma who received chemoradiotherapy with S-1 (tegafur-gimeracil-oteracil potassium)."3.80Radiotherapy concurrent with S-1 and radiotherapy alone for T2N0 glottic carcinoma: a retrospective comparative study. ( Higashino, M; Ichihara, S; Kawata, R; Lee, K; Nishikawa, S; Uesugi, Y, 2014)
"In the current study, we have evaluated the clinical and immunological responses in patients with advanced pancreatic carcinoma who received dendritic cell (DC)-based immunotherapy in combination with gemcitabine and/or S-1."3.78Clinical and immunologic evaluation of dendritic cell-based immunotherapy in combination with gemcitabine and/or S-1 in patients with advanced pancreatic carcinoma. ( Homma, S; Imai, K; Kimura, Y; Koido, S; Okamoto, M; Shimamura, K; Shimodaira, S; Sunamura, M; Takahashi, H; Tomoda, T; Tsukada, J; Yonemitsu, Y, 2012)
"Adjuvant gemcitabine plus S-1 chemotherapy may be one of several factors contributing to improved outcomes after aggressive surgical resection of advanced biliary carcinoma in recent years."3.75Adjuvant gemcitabine plus S-1 chemotherapy improves survival after aggressive surgical resection for advanced biliary carcinoma. ( Hashimoto, Y; Hayashidani, Y; Murakami, Y; Nakamura, H; Nakashima, A; Sudo, T; Sueda, T; Uemura, K, 2009)
" Using a murine dorsal air sac (DAS) assay, we have previously shown that UFT and its metabolites, gamma-hydroxybutyric acid (GHB) and 5-fluorouracil (5-FU), inhibited the angiogenesis induced by murine renal cell carcinoma."3.71gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor. ( Aoyagi, K; Basaki, Y; Chikahisa, L; Hashimoto, A; Miyadera, K; Okabe, S; Wierzba, K; Yamada, Y; Yonekura, K, 2001)
" In a previous study, the authors demonstrated that the combination of uracil and tegafur (UFT) with leucovorin (LV) was active and well tolerated in patients with advanced colorectal carcinoma (ACC)."3.69Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group. ( Colmenarejo, A; de Castro, J; de la Gándara, I; Espinosa, E; Espinosa, J; Feliu, J; Fernández, Y; García Girón, C; González Barón, M; Jalón, JI, 1997)
"Eighty-nine patients with advanced gastric carcinoma were treated with a combination chemo-immunotherapy regimen that consisted of active immunotherapy with Vibrio cholerae neuraminidase (VCN) treated autologous tumor cells admixed with BCG and drugs including cyclophosphamide, mitomycin C (MMC) and 5-fluorouracil, followed by long term tegafur (FT) and immunomodulators."3.67Combination chemoimmunotherapy for advanced gastric carcinoma. ( Akiyoshi, T; Arinaga, S; Kawaguchi, M; Koba, F; Miyazaki, S; Tsuji, H; Wada, T, 1984)
"Effects of N-(6-aminohexyl)-1-naphthalenesulfonamide (W-5) and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur, FT) and a mixture of FT and uracil (UFT) were determined in nude mice bearing human ovarian carcinoma (KF cells)."3.67Adjuvant effects of calmodulin antagonists on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur) and a mixture of ftorafur and uracil (UFT) in nude mice bearing human ovarian carcinomas. ( Iwano, I; Kikuchi, Y; Kita, T; Kizawa, I; Kuki, E; Miyauchi, M; Oomori, K, 1989)
" The antitumor activity of this compound was superior to those of 5-FU and 1-(2-tetrahydrofuryl)-5-fluorouracil (Tegafur, Ftorafur) in the treatment of transplantable tumors, not only 5-FU-sensitive tumors such as adenocarcinoma 755, lymphosarcoma LS-1, and plasmacytoma X5563, but also 5-FU-resistant tumors such as Lewis lung carcinoma and Walker carcinosarcoma 256."3.66Antitumor activity of methyl (5-fluoro-1H-2-oxo-4-pyrimidinyl beta-D-glucopyranosid)uronate against various experimental tumors. ( Arakawa, M; Inomata, T; Sasagawa, K; Shimizu, F; Shinkai, K, 1981)
"Irinotecan was administered intravenously over the course of 90 minutes on day 1, and S-1 was given orally in 2 divided doses from days 1 to 14 of a 21-day cycle."2.82Phase I Clinical Study of Irinotecan Plus S-1 in Patients With Advanced or Recurrent Cervical Cancer Previously Treated With Platinum-Based Chemotherapy. ( Kimura, T; Kobayashi, E; Kozasa, K; Mabuchi, S; Owa, T; Tomimatsu, T; Tsutui, T; Yamashita, M; Yoki, T; Yokoi, E, 2016)
"The response rate of S-1 for colorectal cancer is high, ranging from 35% to 40%."2.75Phase II study of S-1 plus leucovorin in patients with metastatic colorectal cancer. ( Boku, N; Furuhata, T; Hyodo, I; Kato, T; Koizumi, W; Miyashita, K; Miyata, Y; Nishina, T; Okada, Y; Sawaki, A; Toh, Y; Yamaguchi, K, 2010)
" GEM was administrated at a dosage of 1 g/m(2) intravenously weekly 3 of 4 weeks and UFT at a dosage of 200 mg/day orally continuously."2.73A randomized phase II trial of adjuvant chemotherapy with uracil/tegafur and gemcitabine versus gemcitabine alone in patients with resected pancreatic cancer. ( Furukawa, K; Ito, H; Kato, A; Kimura, F; Miyazaki, M; Nozawa, S; Otsuka, M; Shimizu, H; Togawa, A; Yoshidome, H; Yoshitomi, H, 2008)
"Distant metastases rate (DMR) was significantly reduced with CRT (14."2.71Concurrent and adjuvant chemotherapy for nasopharyngeal carcinoma: a factorial study. ( Au, GK; Chan, RT; Cheng, AC; Choy, DD; Chua, DT; Kwok, CC; Kwong, DL; Kwong, PW; Law, MW; Sham, JS; Wan, KY; Wu, PM; Yau, CC, 2004)
"No effective treatment for advanced esophageal cancer extending to adjacent organs or associated with distant metastasis is known."2.71Concurrent chemoradiotherapy for locally advanced and metastatic esophageal cancer: longterm results of a phase II study of UFT/CDDP with radiotherapy. ( Horiuchi, Y; Indo, T; Iwase, H; Iyo, T; Kaida, S; Kato, E; Kusugami, K; Nakamura, M; Nakarai, K; Shimada, M, 2003)
"The main toxicity was diarrhea and oral mucositis."2.68Phase II trial of Oral UFT and leucovorin in advanced gastric carcinoma. ( Cheong, SK; Kim, JS; Kim, YH; Lee, JD; Park, JS; Shin, SW, 1996)
"G-CSF producing anaplastic carcinoma of the pancreas is extremely rare and there are no reports with regard to response evaluation by FDG-PET."2.49[An autopsy of G-CSF-producing anaplastic carcinoma of the pancreas with impaired accumulation on FDG-PET after S-1 chemotherapy]. ( Ikeda, S; Ito, T; Kanazawa, H; Katada, N; Morita, K; Narita, M; Nishimura, D; Okubo, K; Shibahara, H; Takeuchi, A, 2013)
"We diagnosed advanced gastric cancer with disseminated carcinomatosis of the bone marrow and multiple bone metastasis."2.47[A very elderly case of advanced gastric cancer with disseminated carcinomatosis of bone marrow and multiple bone metastasis, diagnosed by extremely elevated serum alkaline phosphatase levels, and treated with low-dose S-1 to avoid disseminated intravascu ( Ashida, C; Higashida, A; Kawara, F; Kondo, T; Mamori, S; Okutani, T; Onishi, K; Takeda, A; Yamada, H, 2011)
"S-1 monotherapy is considered a safe and effective treatment option for recurrent and metastatic nasopharyngeal carcinoma patients after failure of platinum-based chemotherapy."1.40Safety and efficacy of S-1 chemotherapy in recurrent and metastatic nasopharyngeal carcinoma patients after failure of platinum-based chemotherapy: multi-institutional retrospective analysis. ( Chen, ZB; Cheng, H; Lin, Z; Liu, YM; Ou, XQ; Peng, PJ; Tang, YN; Wang, SY; Wu, X; Zeng, LJ; Zhang, HY, 2014)
"Prognosis of patients with metastatic gastric cancer is abysmal, usually just a few months."1.40[Case report of a patient with advanced and disseminated gastric carcinoma treated by s-1]. ( Katolická, J; Rotnáglová, S; Vaníček, J, 2014)
"We report a case of gastric cancer accompanied by disseminated carcinomatosis of the bone marrow treated with S-1 and cisplatin( CDDP) combination chemotherapy."1.39[A case of gastric cancer accompanied by disseminated carcinomatosis of the bone marrow successfully controlled by S-1 and cisplatin combination therapy]. ( Amagasa, H; Ami, K; Ando, M; Aoki, N; Arai, K; Fujiya, K; Fukuda, A; Ganno, H; Imai, K; Kamikozuru, H; Nagahama, T; Ohbu, M; Takeuchi, S; Tei, S, 2013)
"Twenty-eight patients with advanced gastric cancer underwent gastrectomy without preoperative chemotherapy."1.39Adjuvant chemotherapy with S-1 followed by docetaxel for gastric cancer and CY1P0 peritoneal metastasis after relatively curative surgery. ( Fujita, I; Kanazawa, Y; Kato, S; Onodera, H; Uchida, E, 2013)
"Thymic carcinoma is a rare intrathoracic malignant tumor, and the prognosis for patients with advanced stage of the disease is poor."1.36S-1 is an active anticancer agent for advanced thymic carcinoma. ( Hosomi, Y; Iguchi, M; Okamura, T; Okuma, Y; Shibuya, M; Shimokawa, T; Takagi, Y, 2010)
"We diagnosed disseminated carcinomatosis of bone marrow by gastric cancer."1.35[A case of advanced gastric cancer with disseminated carcinomatosis of bone marrow treated by S-1 and CDDP]. ( Fujishima, Y; Fukuda, T; Fukunaga, H; Iwai, M; Koide, M; Miura, M; Yoneda, R, 2009)
"We report a case of anaplastic carcinoma of the thyroid administered peroral fluorinated pyrimidine, providing longterm survival during three years."1.35[A case of anaplastic carcinoma of thyroid administered peroral fluorinated pyrimidine for long-term survival during three years]. ( Kira, M; Takizawa, H; Tangoku, A; Toba, H; Yamai, H; Yoshida, T, 2009)
" Pharmacokinetic modulating chemotherapy (PMC), a combination of infused 5-fluorouracil and oral uracil-tegafur, has been proven to be highly effective for the treatment of colorectal carcinoma."1.32Modified pharmacokinetic modulating chemotherapy using 5-fluorouracil, UFT, and taxotere (docetaxel) for advanced gastric cancer. ( Kobayashi, M; Konishi, N; Kusunoki, M; Mohri, Y; Ohmori, Y; Tanaka, K; Tonouchi, H, 2003)
" Rats were dosed p."1.295-Ethynyluracil (776C85): effects on the antitumor activity and pharmacokinetics of tegafur, a prodrug of 5-fluorouracil. ( Baccanari, DP; Cao, S; Davis, ST; Joyner, SS; Rustum, YM; Spector, T, 1995)
"A 66-year-old woman with left breast cancer (medullary carcinoma; T1cN1M0; Stage II A) was treated with breast conserving therapy combined with lumpectomy, radiotherapy, chemotherapy and endocrine therapy beginning in March, 1990."1.28[A case report of bone metastasis diagnosed by MRI and effectively treated with UFT after breast conserving therapy for breast cancer]. ( Hamada, N; Inomata, T; Nishioka, A; Ogawa, Y; Ogoshi, S; Sawada, A; Tanaka, Y; Terashima, M, 1992)
"A case of right breast and thyroid cancer is reported in which, despite metastasis to the spinal cord occurring 1 year after mastectomy, satisfactory therapeutic results were obtained."1.27[Complete remission in a case of concurrent breast and thyroid cancers with metastatic spinal paralysis]. ( Kure, M; Niwa, M; Ohganè, T, 1986)

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-199021 (23.60)18.7374
1990's15 (16.85)18.2507
2000's22 (24.72)29.6817
2010's28 (31.46)24.3611
2020's3 (3.37)2.80

Authors

AuthorsStudies
Itano, O1
Takemura, Y1
Kishida, N1
Tamagawa, E1
Shinozaki, H1
Ikeda, K1
Urakami, H1
Ei, S1
Hayatsu, S1
Suzuki, K1
Sakuragawa, T1
Ishii, M1
Shito, M1
Aiura, K1
Fujisaki, H1
Takano, K1
Matsui, J1
Minagawa, T1
Shinoda, M1
Kitago, M1
Abe, Y1
Yagi, H1
Oshima, G1
Hori, S1
Kitagawa, Y2
Imaoka, H1
Ikeda, M2
Maehara, K1
Umemoto, K1
Ozaka, M1
Kobayashi, S2
Terashima, T1
Inoue, H1
Sakaguchi, C1
Tsuji, K2
Shioji, K1
Okamura, K1
Kawamoto, Y1
Suzuki, R1
Shirakawa, H1
Nagano, H1
Ueno, M1
Morizane, C2
Furuse, J2
Li, Y1
Cui, L1
Chen, Y1
Wang, F1
Doi, T1
Sakamoto, T1
Okino, T1
Ikeda, S1
Okubo, K1
Shibahara, H1
Narita, M1
Morita, K1
Takeuchi, A1
Kanazawa, H1
Ito, T1
Nishimura, D1
Katada, N1
Tsuya, A1
Kurata, T1
Tamiya, A1
Okamoto, I2
Ueda, S1
Sakai, D1
Sugimoto, N1
Matsumoto, K2
Goto, I1
Yamamoto, N2
Fukuoka, M2
Nakagawa, K2
Sunaga, T1
Suzuki, S1
Kogo, M1
Kurihara, T1
Kaji, S1
Koike, N1
Harada, N1
Suzuki, M3
Kiuchi, Y1
Kanazawa, Y1
Kato, S1
Fujita, I1
Onodera, H1
Uchida, E1
Ganno, H1
Nagahama, T1
Fukuda, A1
Takeuchi, S2
Fujiya, K1
Amagasa, H1
Kamikozuru, H1
Imai, K2
Ami, K1
Aoki, N2
Ando, M1
Arai, K1
Tei, S1
Ohbu, M1
Fujisawa, Y1
Fujimoto, M1
Higashino, M1
Kawata, R1
Lee, K1
Nishikawa, S1
Ichihara, S1
Uesugi, Y1
Katolická, J1
Rotnáglová, S1
Vaníček, J1
Peng, PJ1
Cheng, H1
Ou, XQ1
Zeng, LJ1
Wu, X1
Liu, YM1
Lin, Z1
Tang, YN1
Wang, SY1
Zhang, HY1
Chen, ZB1
Murakami, Y4
Uemura, K4
Sudo, T4
Hashimoto, Y4
Kondo, N3
Nakagawa, N2
Sasaki, H1
Sueda, T4
Yoshida, M1
Muro, K1
Tsuji, A2
Hamamoto, Y1
Yoshino, T1
Yoshida, K1
Shirao, K1
Miyata, Y2
Takahari, D1
Takahashi, T2
Ohtsu, A1
Hayashi, H1
Eguchi, N1
Sumimoto, K1
Azakami, T1
Sumida, T1
Tamura, T1
Sumii, M1
Uraoka, N1
Shimamoto, F1
Mabuchi, S1
Yokoi, E1
Owa, T1
Kozasa, K1
Yamashita, M1
Kobayashi, E1
Tomimatsu, T1
Yoki, T1
Tsutui, T1
Kimura, T2
Koda, K1
Miyauchi, H1
Kosugi, C1
Kaiho, T1
Takiguchi, N1
Maruyama, T2
Matsubara, H1
Yoshitomi, H1
Togawa, A1
Kimura, F1
Ito, H1
Shimizu, H2
Yoshidome, H1
Otsuka, M1
Kato, A1
Nozawa, S1
Furukawa, K1
Miyazaki, M1
Yamai, H1
Yoshida, T1
Toba, H1
Kira, M1
Takizawa, H1
Tangoku, A1
Tanigawa, T1
Miyamoto, Y1
Abe, M1
Hasuo, T1
Doiguchi, M1
Sakamoto, F1
Koizumi, W1
Boku, N1
Yamaguchi, K1
Sawaki, A1
Kato, T1
Toh, Y2
Hyodo, I1
Nishina, T1
Furuhata, T1
Miyashita, K1
Okada, Y1
Hayashidani, Y1
Nakamura, H1
Nakashima, A3
Fujishima, Y1
Yoneda, R1
Iwai, M1
Fukunaga, H1
Miura, M1
Koide, M1
Fukuda, T1
Tanizaki, J1
Takezawa, K1
Tsukioka, S1
Uchida, J1
Kiniwa, M1
Hashiguchi, K1
Kitajima, Y1
Kai, K1
Hiraki, M1
Nakamura, J1
Tokunaga, O1
Noshiro, H1
Miyazaki, K1
Yoon, DH1
Cho, Y1
Kim, SY1
Nam, SY1
Choi, SH1
Roh, JL1
Lee, SW1
Song, SY1
Lee, JH1
Kim, JS4
Cho, KJ1
Kim, SB1
Okuma, Y1
Shimokawa, T1
Takagi, Y1
Hosomi, Y1
Iguchi, M1
Okamura, T2
Shibuya, M1
Kogashiwa, Y1
Yamauchi, K1
Nagafuji, H1
Matsuda, T1
Tsubosaka, T1
Karaho, T1
Kohno, N1
Yabe, N1
Murai, S1
Akatsu, T1
Shoji, T1
Fukushima, H1
Mitsugi, Y1
Ishida, T1
Amemiya, T1
Hasegawa, H2
Kimura, Y1
Tsukada, J1
Tomoda, T1
Takahashi, H1
Shimamura, K1
Sunamura, M1
Yonemitsu, Y1
Shimodaira, S1
Koido, S1
Homma, S1
Okamoto, M1
Takeda, A1
Kawara, F1
Onishi, K1
Higashida, A1
Mamori, S1
Ashida, C1
Okutani, T1
Yamada, H1
Kondo, T1
Wang, JL1
Bi, Z1
Zou, JW1
Gu, XM1
Sakabe, R1
Ohge, H1
Hiyama, E1
Doyama, H1
Yamada, S1
Kaneko, Y1
Takemura, K1
Tsuji, S1
Tominaga, K1
Inagaki, S1
Hayashi, T1
Ito, R1
Nakanishi, H2
Kitou, Y1
Takeda, Y1
Yamamoto, M1
Inaki, N1
Yamada, T1
Niwa, H1
Katayanagi, K1
Kurumaya, H1
Mochizuki, Y1
Kodera, Y1
Ito, S1
Yamamura, Y1
Ito, K1
Akiyama, S1
Nakao, A1
Tatematsu, M1
Takahashi, K1
Miyagawa, K1
Mitachi, Y2
Masuda, T1
Oogoshi, T1
Kawami, H1
Shigematsu, H1
Fujimoto, Y1
Iwase, H1
Shimada, M1
Nakamura, M1
Nakarai, K1
Iyo, T1
Kaida, S1
Indo, T1
Kato, E1
Horiuchi, Y1
Kusugami, K1
Tanaka, K1
Konishi, N1
Ohmori, Y1
Kobayashi, M1
Mohri, Y1
Tonouchi, H1
Kusunoki, M1
Veldhorst-Janssen, NM1
Boersma, HH1
de Krom, MC1
van Rijswijk, RE1
Nakayama, A1
Ishida, S1
Katsuragi, A1
Adachi, M1
Kwong, DL1
Sham, JS1
Au, GK1
Chua, DT1
Kwong, PW1
Cheng, AC1
Wu, PM1
Law, MW1
Kwok, CC1
Yau, CC1
Wan, KY1
Chan, RT1
Choy, DD1
Jentsch-Ullrich, K1
Kalinski, T1
Roessner, A1
Franke, A1
Mohren, M1
Ishigami, S1
Nakajo, A1
Uenosono, Y1
Okumura, H1
Matsumoto, M1
Arigami, T1
Uchikado, Y1
Setoyama, T1
Hokita, S1
Natsugoe, S1
Aikou, T1
Okusaka, T1
Ito, Y1
Ueno, H1
Ishii, H1
Kawashima, M1
Kagami, Y1
Ikeda, H2
Morita, S1
Nakata, B1
Shirasaka, T1
Saji, S1
Ohashi, Y1
Sakamoto, J1
Hirakawa, K1
Kim, YH4
Seo, HY1
Jeen, YT2
Kim, HK1
Shim, BY1
Yang, J1
Fujita, F1
Fujita, M1
Taguchi, T2
Kano, T1
Kumashiro, R1
Masuda, H1
Tamada, R1
Inokuchi, K1
Akiyoshi, T1
Kawaguchi, M1
Arinaga, S1
Miyazaki, S1
Koba, F1
Wada, T1
Tsuji, H1
Grigorova, TM1
Vartanian, LG1
Marenich, AF1
Narisawa, T1
Sato, M1
Tani, M1
Arakawa, M1
Shimizu, F1
Sasagawa, K1
Inomata, T2
Shinkai, K1
Blokhina, NG1
Sorokina, GA1
Cao, S1
Baccanari, DP1
Joyner, SS1
Davis, ST1
Rustum, YM1
Spector, T1
Cheong, SK1
Lee, JD1
Park, JS1
Shin, SW3
Sakai, K1
Kosaki, G1
Seno, T1
Terasawa, T1
Nakao, K1
Koyama, H1
Oshima, A1
Feliu, J2
González Barón, M2
García-Girón, C1
Espinosa, E2
García-Alfonso, P1
Belón, J1
Blanco, E1
Garrido, P1
Ordónez, A1
Gómez-Navarro, J1
Zamora, P1
Pazdur, R2
García Girón, C1
de la Gándara, I1
Espinosa, J1
Colmenarejo, A1
Jalón, JI1
Fernández, Y1
de Castro, J1
Kim, BS2
Park, YT1
Kim, JG1
Lassere, Y1
Diaz-Canton, E1
Ho, DH1
Nogué, M1
Seguí, MA1
Saigí, E1
Batiste-Alentorn, E1
Arcusa, A1
Boleda, M1
Antón, I1
Oki, E1
Sakaguchi, Y1
Oda, S1
Maehara, Y1
Sugimachi, K2
Rubiales, AS1
del Valle, ML1
Schilling, G1
Lipp, R1
Hegewisch-Becker, S1
Hossfeld, DK1
Yoon, SY1
Mok, YJ1
Kim, CS1
Hyun, JH1
Reimer, P1
Rückle-Lanz, H1
Basaki, Y1
Chikahisa, L1
Aoyagi, K1
Miyadera, K1
Yonekura, K1
Hashimoto, A1
Okabe, S1
Wierzba, K1
Yamada, Y1
Garibjanian, BT1
Johnson, RK1
Kline, I1
Vadlamudi, S1
Gang, M1
Venditti, JM1
Goldin, A1
Nishioka, A1
Ogawa, Y1
Hamada, N1
Terashima, M1
Sawada, A1
Tanaka, Y1
Ogoshi, S1
Moreira, LF1
Iwagaki, H1
Hizuta, A1
Sakagami, K1
Mimura, H1
Orita, K1
Ushio, Y1
Arita, N1
Hayakawa, T1
Mogami, H1
Bitoh, S1
Oku, Y1
Kanai, N1
Kanoh, M1
Unda Urzaiz, M1
Zubiaur Líbano, C1
Pérez Fernández, A1
Iriarte Soldevilla, JI1
Flores Corral, N1
Korenaga, D1
Baba, H1
Saito, A1
Vachalovský, V1
Vomácka, V1
Kikuchi, Y1
Oomori, K1
Iwano, I1
Kizawa, I1
Miyauchi, M1
Kita, T1
Kuki, E1
Treat, J1
Falchuk, SC1
Woolley, PV1
Ahlgren, JD1
Neefe, JR1
Smith, FP1
Macdonald, JS1
Schein, PS1
Matsumoto, S1
Kutsuna, T1
Tann, M1
Mizuno, Y1
Shinohara, M1
Banno, T1
Yoshizaki, S1
Sugawa, T1
Yamagata, S1
Koyama, S1
Ozaki, A1
Iwasaki, Y1
Sakita, T1
Osuga, T1
Watanabe, A1
Kawasaki, T1
Soma, T1
Tabuchi, T1
Ohganè, T1
Niwa, M1
Kure, M1
Pasterz, R1
Savaraj, N1
Burgess, M1
Zhero, SV1
Ganina, KP1
Hanaue, H1
Kurosawa, T1
Kitano, Y1
Miyakawa, S1
Nemoto, A1
Yamoto, H1
Asagoe, T1
Shikata, J1
Peek, U1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
PD-1 Antibody Plus Gemcitabine and Oxaliplatin (GEMOX) as Postoperative Adjuvant Therapy in Perihilar Cholangiocarcinoma Patients With Positively Metastatic Lymph Nodes : a Single Arm, Phase II Trial[NCT05430698]Phase 262 participants (Anticipated)Interventional2023-01-31Recruiting
Phase II Study of S-1 Plus Leucovorin (1 Week on and 1 Week Off) as First-line Treatment for Patients With Metastatic and Recurrent Gastric Cancer[NCT02090153]Phase 239 participants (Actual)Interventional2011-07-31Completed
A Phase II Study Assessing Efficacy and Safety of TS-1 in Combination With Calcium Folinate in Patients With Heavily Pre-treated Metastatic Colorectal Cancer[NCT03517618]Phase 241 participants (Actual)Interventional2014-07-05Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for tegafur and Carcinoma, Anaplastic

ArticleYear
[An autopsy of G-CSF-producing anaplastic carcinoma of the pancreas with impaired accumulation on FDG-PET after S-1 chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:6

    Topics: Aged; Antimetabolites, Antineoplastic; Autopsy; Carcinoma; Drug Combinations; Fatal Outcome; Female;

2013
Autopsy of anaplastic carcinoma of the pancreas producing granulocyte colony-stimulating factor.
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2016, Volume: 113, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autopsy; Biopsy; Carcinoma; Deoxycytidine; Drug Comb

2016
[A very elderly case of advanced gastric cancer with disseminated carcinomatosis of bone marrow and multiple bone metastasis, diagnosed by extremely elevated serum alkaline phosphatase levels, and treated with low-dose S-1 to avoid disseminated intravascu
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2011, Volume: 108, Issue:11

    Topics: Aged, 80 and over; Alkaline Phosphatase; Antimetabolites, Antineoplastic; Bone Marrow Neoplasms; Bon

2011
[New therapeutic options in chemotherapy of advanced colorectal cancer].
    Medizinische Klinik (Munich, Germany : 1983), 2001, Oct-15, Volume: 96, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Carcinoma; Clinical Tria

2001

Trials

27 trials available for tegafur and Carcinoma, Anaplastic

ArticleYear
A phase II study of cisplatin /S-1 in patients with carcinomas of unknown primary site.
    Investigational new drugs, 2013, Volume: 31, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma; Cisplatin; Drug Combinat

2013
Combination chemotherapy with bevacizumab and S-1 for elderly patients with metastatic colorectal cancer (BASIC trial).
    European journal of cancer (Oxford, England : 1990), 2015, Volume: 51, Issue:8

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2015
Phase I Clinical Study of Irinotecan Plus S-1 in Patients With Advanced or Recurrent Cervical Cancer Previously Treated With Platinum-Based Chemotherapy.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2016, Volume: 26, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Ca

2016
Tumor 5-FU-related mRNA Expression and Efficacy of Oral Fluoropyrimidines in Adjuvant Chemotherapy of Colorectal Cancer.
    Anticancer research, 2016, Volume: 36, Issue:10

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma; Chemotherapy, Adjuvan

2016
A randomized phase II trial of adjuvant chemotherapy with uracil/tegafur and gemcitabine versus gemcitabine alone in patients with resected pancreatic cancer.
    Cancer, 2008, Nov-01, Volume: 113, Issue:9

    Topics: Adenocarcinoma, Papillary; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; C

2008
Phase II study of S-1 plus leucovorin in patients with metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colore

2010
Phase II study of S-1 plus leucovorin in patients with metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colore

2010
Phase II study of S-1 plus leucovorin in patients with metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colore

2010
Phase II study of S-1 plus leucovorin in patients with metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colore

2010
Phase I study of S-1 plus nedaplatin in patients with advanced/recurrent head and neck cancer.
    Chemotherapy, 2010, Volume: 56, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell; Cisplatin

2010
Combination therapy with lentinan improves outcomes in patients with esophageal carcinoma.
    Molecular medicine reports, 2012, Volume: 5, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma; Cytokines; Drug Therapy, Combination; Esophageal Neop

2012
Long-term results of adjuvant gemcitabine plus S-1 chemotherapy after surgical resection for pancreatic carcinoma.
    Journal of surgical oncology, 2012, Aug-01, Volume: 106, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antimetabolites, Antineoplasti

2012
Concurrent chemoradiotherapy for locally advanced and metastatic esophageal cancer: longterm results of a phase II study of UFT/CDDP with radiotherapy.
    International journal of clinical oncology, 2003, Volume: 8, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Combi

2003
Concurrent and adjuvant chemotherapy for nasopharyngeal carcinoma: a factorial study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Jul-01, Volume: 22, Issue:13

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcin

2004
A phase I trial of S-1 with concurrent radiotherapy for locally advanced pancreatic cancer.
    British journal of cancer, 2007, Jun-04, Volume: 96, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Combined Modality Therapy; Dose-Res

2007
A phase I study of combination therapy of the oral fluorinated pyrimidine compound S-1 with low-dose cisplatin twice-a-week administration (JFMC27-9902 Step2) in patients with advanced gastric cancer using a continual reassessment method.
    Japanese journal of clinical oncology, 2007, Volume: 37, Issue:12

    Topics: Administration, Oral; Adult; Aged; Algorithms; Antimetabolites, Antineoplastic; Antineoplastic Combi

2007
Phase I dose escalation study of docetaxel with a fixed dose of S-1 in combination chemotherapy for advanced gastric cancer.
    Cancer chemotherapy and pharmacology, 2009, Volume: 63, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Docetaxel; Dose-Response Rel

2009
Phase II trial of Oral UFT and leucovorin in advanced gastric carcinoma.
    American journal of clinical oncology, 1996, Volume: 19, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antibiotics, Antineoplastic; Antidotes; Antimetabolites, Antineop

1996
A randomized trial comparing ftorafur alone with ftorafur plus tamoxifen in postoperative adjuvant therapy for breast cancer. Kinki Area Research Group for Postoperative Adjuvant Therapy for Breast Cancer.
    Cancer chemotherapy and pharmacology, 1996, Volume: 37, Issue:6

    Topics: Adult; Aged; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Female; Humans; Middle Aged; Su

1996
Treatment of patients with advanced gastric carcinoma with the combination of etoposide plus oral tegafur modulated by uracil and leucovorin. A phase II study of the ONCOPAZ Cooperative Group.
    Cancer, 1996, Jul-15, Volume: 78, Issue:2

    Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Anemia; Antidotes; Antimetabolites, Antineoplast

1996
Phase II study of UFT plus leucovorin in colorectal cancer.
    Oncology, 1997, Volume: 54 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Drug Combinations;

1997
A phase II trial. Oral UFT and leucovorin in patients with advanced gastric carcinoma.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Diarrhea; Drug Co

1997
Phase I trial of uracil-tegafur (UFT) plus oral leucovorin: 28-day schedule.
    Cancer investigation, 1998, Volume: 16, Issue:3

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Coloni

1998
Protracted treatment with tegafur and low dose oral leucovorin in patients with advanced colorectal carcinoma.
    Cancer, 1998, Jul-15, Volume: 83, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Carcinoma; Colorectal

1998
UFT/leucovorin plus weekly irinotecan in advanced or metastatic colorectal cancer.
    Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:10 Suppl 9

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemot

2000
Phase II trial of epirubicin, cisplatin, oral uracil and tegafur, and leucovorin in patients with advanced gastric carcinoma.
    Cancer, 2001, Jun-15, Volume: 91, Issue:12

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cispla

2001
Chemotherapy of brain metastases from lung carcinoma: a controlled randomized study.
    Neurosurgery, 1991, Volume: 28, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Carcinom

1991
[Adriamycin versus ftorafur in the prevention of recurrence of superficial carcinoma of the bladder].
    Archivos espanoles de urologia, 1990, Volume: 43, Issue:2

    Topics: Carcinoma; Doxorubicin; Drug Evaluation; Humans; Neoplasm Recurrence, Local; Neoplasm Staging; Prosp

1990
[Orimeten in the treatment of advanced carcinoma of the prostate].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1989, Volume: 68, Issue:4

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Agents; Carcinoma; Cyclophosphamide; Drug

1989
Randomized controlled study of postoperative adjuvant immunochemotherapy with Nocardia rubra cell wall skeleton (N-CWS) and Tegafur for gastric carcinoma.
    Cancer immunology, immunotherapy : CII, 1986, Volume: 22, Issue:2

    Topics: Actuarial Analysis; Adjuvants, Immunologic; Aged; Carcinoma; Cell Wall; Clinical Trials as Topic; Fe

1986

Other Studies

58 other studies available for tegafur and Carcinoma, Anaplastic

ArticleYear
A prospective feasibility study of one-year administration of adjuvant S-1 therapy for resected biliary tract cancer in a multi-institutional trial (Tokyo Study Group for Biliary Cancer: TOSBIC01).
    BMC cancer, 2020, Jul-23, Volume: 20, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Ampulla of Vater; Bile Duct Neoplasms; Carcino

2020
Clinical outcomes of chemotherapy in patients with undifferentiated carcinoma of the pancreas: a retrospective multicenter cohort study.
    BMC cancer, 2020, Oct-01, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Deoxycyti

2020
Carcinosarcoma and sarcomatoid carcinoma of the stomach: Two case reports.
    Medicine, 2021, Mar-26, Volume: 100, Issue:12

    Topics: Abdominal Pain; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinosarcoma; Che

2021
[Pulmonary Metastasis of Gastric Cancer as Carcinomatous Lymphangiosis at Five and Half Years after Surgery;Report of a Case].
    Kyobu geka. The Japanese journal of thoracic surgery, 2018, Volume: 71, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma; Chemotherapy, Adjuvant; Doc

2018
The association between neutropenia and prognosis in stage III colorectal cancer patients receiving adjuvant chemotherapy.
    European journal of cancer care, 2014, Volume: 23, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemother

2014
Adjuvant chemotherapy with S-1 followed by docetaxel for gastric cancer and CY1P0 peritoneal metastasis after relatively curative surgery.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2013, Volume: 80, Issue:5

    Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy

2013
[A case of gastric cancer accompanied by disseminated carcinomatosis of the bone marrow successfully controlled by S-1 and cisplatin combination therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Carcinoma; Cisplatin; D

2013
Metastatic cutaneous apocrine carcinoma of the axilla successfully treated using systemic chemotherapy with i.v. epirubicin and cyclophosphamide followed by oral fluorinated pyrimidine.
    The Journal of dermatology, 2014, Volume: 41, Issue:3

    Topics: Adult; Antineoplastic Agents; Axilla; Carcinoma; Cyclophosphamide; Drug Combinations; Epirubicin; Hu

2014
Radiotherapy concurrent with S-1 and radiotherapy alone for T2N0 glottic carcinoma: a retrospective comparative study.
    Auris, nasus, larynx, 2014, Volume: 41, Issue:4

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma; Chemoradiotherapy; Drug Combina

2014
[Case report of a patient with advanced and disseminated gastric carcinoma treated by s-1].
    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2014, Volume: 27, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P

2014
Safety and efficacy of S-1 chemotherapy in recurrent and metastatic nasopharyngeal carcinoma patients after failure of platinum-based chemotherapy: multi-institutional retrospective analysis.
    Drug design, development and therapy, 2014, Volume: 8

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma; Disease Progression; Drug Combinations; Fem

2014
Is pancreatic fistula associated with worse overall survival in patients with pancreatic carcinoma?
    World journal of surgery, 2015, Volume: 39, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemother

2015
[A case of anaplastic carcinoma of thyroid administered peroral fluorinated pyrimidine for long-term survival during three years].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:6

    Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Pr

2009
[A case of inflammatory carcinoma, well-controlled by chemotherapy, especially, vinorelbine, S-1 and trastuzumab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:9

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineop

2009
Adjuvant gemcitabine plus S-1 chemotherapy improves survival after aggressive surgical resection for advanced biliary carcinoma.
    Annals of surgery, 2009, Volume: 250, Issue:6

    Topics: Aged; Antimetabolites, Antineoplastic; Biliary Tract Neoplasms; Carcinoma; Chemotherapy, Adjuvant; D

2009
[A case of advanced gastric cancer with disseminated carcinomatosis of bone marrow treated by S-1 and CDDP].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:13

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplas

2009
Synergistic antitumor effect of S-1 and HER2-targeting agents in gastric cancer with HER2 amplification.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemothe

2010
A quantitative evaluation of the determinant proteins for S-1 responsiveness in a biopsy specimen assists in patient selection to neoadjuvant therapy in cases of advanced gastric cancer.
    International journal of oncology, 2010, Volume: 37, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmaco

2010
Usefulness of interim FDG-PET after induction chemotherapy in patients with locally advanced squamous cell carcinoma of the head and neck receiving sequential induction chemotherapy followed by concurrent chemoradiotherapy.
    International journal of radiation oncology, biology, physics, 2011, Sep-01, Volume: 81, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell; Ci

2011
S-1 is an active anticancer agent for advanced thymic carcinoma.
    Lung cancer (Amsterdam, Netherlands), 2010, Volume: 70, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma; Disease Progression; Disease-Free Survival; Drug C

2010
[A case of advanced gastric cancer resistant to S-1 successfully treated with weekly administration of paclitaxel].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Carcinoma; Drug

2010
Clinical and immunologic evaluation of dendritic cell-based immunotherapy in combination with gemcitabine and/or S-1 in patients with advanced pancreatic carcinoma.
    Pancreas, 2012, Volume: 41, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols

2012
Prognostic significance of telomerase activity and human telomerase reverse transcriptase expression in ampullary carcinoma.
    Annals of surgical oncology, 2012, Volume: 19, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Ampulla of Vater; Antineoplastic Agents; Biomarkers, Tumor; Carcinom

2012
[A case of disseminated carcinomatosis of bone marrow treated by S-1 and cisplatin after distal gastrectomy for early gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Carcinoma; Cisplatin; Dissemi

2012
Chemosensitivity of peritoneal micrometastases as evaluated using a green fluorescence protein (GFP)-tagged human gastric cancer cell line.
    Cancer science, 2003, Volume: 94, Issue:1

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Ascites; Carcinoma; Cell Count; Dose

2003
[A case of gastric cancer with metastasis to cervical lymph nodes and pulmonary lymphangitis carcinomatosa responding to neoadjuvant chemotherapy with TS-1 and CDDP].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Drug Combinations; Gastrectomy

2003
[A case of advanced gastric carcinoma successfully treated with TS-1/CDDP as a neoadjuvant chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemotherapy, Adjuvant; Cisplatin;

2003
Modified pharmacokinetic modulating chemotherapy using 5-fluorouracil, UFT, and taxotere (docetaxel) for advanced gastric cancer.
    International journal of clinical oncology, 2003, Volume: 8, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Docetaxel; Fluorouracil; Humans; Infusion

2003
Oral tegafur/folinic acid chemotherapy decreases phenytoin efficacy.
    British journal of cancer, 2004, Feb-09, Volume: 90, Issue:3

    Topics: Administration, Oral; Anticonvulsants; Antimetabolites, Antineoplastic; Carcinoma; Drug Interactions

2004
[A case of huge submandibular malignant tumor treated successfully with UFT chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:2

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Carcinoma; Combined Modality Therapy; Drug Admini

2004
Long-term remission in a patient with carcinoma of unknown primary site.
    Chemotherapy, 2006, Volume: 52, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Cyclophosphamide; Doxorubicin;

2006
[Clinical efficacy of biweekly paclitaxel and S-1 regimen for 14 gastric cancer patients with liver metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Drug Administration Schedule; Drug

2007
[Effects of 5'-deoxy-5-fluorouridine on human gastrointestinal and breast cancers xenografted to nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:8

    Topics: Adenocarcinoma; Administration, Oral; Animals; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Femal

1984
Late results of postoperative long-term cancer chemotherapy for the gastric cancer patients subjected to curative resection.
    The Japanese journal of surgery, 1983, Volume: 13, Issue:2

    Topics: Antibiotics, Antineoplastic; Carcinoma; Dose-Response Relationship, Drug; Drug Administration Schedu

1983
Combination chemoimmunotherapy for advanced gastric carcinoma.
    The Japanese journal of surgery, 1984, Volume: 14, Issue:3

    Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Ca

1984
[Surgical method and combination chemotherapy in treating stage-III and IV ovarian cancer].
    Voprosy onkologii, 1980, Volume: 26, Issue:2

    Topics: Altretamine; Antineoplastic Agents; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Evaluati

1980
Chemoprevention of development of colonic adenomatosis and carcinomatosis with 5-fluorouracil and ftorafur on animal model.
    Journal of cancer research and clinical oncology, 1980, Volume: 97, Issue:3

    Topics: Adenoma; Animals; Carcinoma; Colon; Colonic Neoplasms; Female; Fluorouracil; Methylnitrosourea; Neop

1980
Antitumor activity of methyl (5-fluoro-1H-2-oxo-4-pyrimidinyl beta-D-glucopyranosid)uronate against various experimental tumors.
    Gan, 1981, Volume: 72, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma 256, Walker; Female; Fluorouracil; Lung Neoplas

1981
[Conservative treatment of primary and recurrent malignant stomach neoplasms].
    Vestnik Akademii meditsinskikh nauk SSSR, 1981, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Male

1981
5-Ethynyluracil (776C85): effects on the antitumor activity and pharmacokinetics of tegafur, a prodrug of 5-fluorouracil.
    Cancer research, 1995, Dec-15, Volume: 55, Issue:24

    Topics: Animals; Carcinoma; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Drug Synergism; Enzyme

1995
Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group.
    Cancer, 1997, May-15, Volume: 79, Issue:10

    Topics: Administration, Oral; Aged; Aged, 80 and over; Ambulatory Care; Antidotes; Antimetabolites, Antineop

1997
Induction of apoptosis in human tumour xenografts after oral administration of uracil and tegafur to nude mice bearing tumours.
    British journal of cancer, 1998, Volume: 78, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma; Cell Division; Colonic Neoplasms; Ga

1998
Protracted treatment with tegafur and low dose oral leucovorin in patients with advanced colorectal carcinoma.
    Cancer, 1999, Apr-15, Volume: 85, Issue:8

    Topics: Administration, Oral; Antidotes; Antimetabolites, Antineoplastic; Carcinoma; Clinical Trials as Topi

1999
gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor.
    Angiogenesis, 2001, Volume: 4, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma; Carc

2001
Comparison of 5-fluorouracil and ftorafur. II. Therapeutic response and development of resistance in murine tumors.
    Cancer treatment reports, 1976, Volume: 60, Issue:9

    Topics: Animals; Carcinoma; Cell Line; Drug Resistance; Drug Therapy, Combination; Female; Fluorouracil; Leu

1976
[A case report of bone metastasis diagnosed by MRI and effectively treated with UFT after breast conserving therapy for breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:13

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast N

1992
Can cytokines prolong survival in ampullary neuroendocrine carcinomas?
    The American journal of gastroenterology, 1992, Volume: 87, Issue:12

    Topics: Ampulla of Vater; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Combined Modality Thera

1992
Postoperative adjuvant chemotherapy inhibits early recurrence of early gastric carcinoma.
    Cancer chemotherapy and pharmacology, 1989, Volume: 23, Issue:5

    Topics: Carcinoma; Combined Modality Therapy; Drug Evaluation; Gastrectomy; Humans; Lymphatic Metastasis; Mi

1989
Adjuvant effects of calmodulin antagonists on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur) and a mixture of ftorafur and uracil (UFT) in nude mice bearing human ovarian carcinomas.
    Gynecologic oncology, 1989, Volume: 35, Issue:2

    Topics: Animals; Calmodulin; Carcinoma; Drug Combinations; Drug Synergism; Female; Fluorouracil; Mice; Mice,

1989
Therapy of advanced gastric carcinoma. The Georgetown-Lombardi Cancer Center experience.
    American journal of clinical oncology, 1989, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Doxorubicin; Fluo

1989
[Mammary gland carcinoma treated by large-dose medroxyprogesterone acetate of which pulmonary metastases disappeared and a selection of hormone, chemoimmunological treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Combined Modality Thera

1989
Reversible leukoencephalopathy caused by 5-fluorouracil derivatives, presenting as akinetic mutism.
    Surgical neurology, 1986, Volume: 25, Issue:3

    Topics: Anal Gland Neoplasms; Animals; Breast Neoplasms; Carcinoma; Female; Fluorouracil; Humans; Leukoencep

1986
[Differing progress patterns in cancer of the uterine cervix and variant effects of adjuvant chemotherapy based on histological type].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:2

    Topics: Adenocarcinoma; Azirines; Carbazilquinone; Carcinoma; Carcinoma, Squamous Cell; Female; Humans; Lymp

1986
[Complete remission in a case of concurrent breast and thyroid cancers with metastatic spinal paralysis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Female; Humans; Middle

1986
Prognostic factors in metastatic carcinoma of unknown primary.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:11

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma;

1986
[Determination of the individual sensitivity of human stomach cancer cells to fluoropyrimidines by the cytomorphological criteria of heterotransplants in diffusion chambers].
    Eksperimental'naia onkologiia, 1986, Volume: 8, Issue:6

    Topics: Adenocarcinoma; Animals; Carcinoma; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Fe

1986
[Drug distribution to lymph and blood in adjuvant chemotherapy with combined preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil and uracil after surgery in gastric cancer patients].
    Nihon Gan Chiryo Gakkai shi, 1987, Aug-20, Volume: 22, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Combined Modality Therapy; Humans; Lymph;

1987
[Inflammatory breast carcinoma--possibilities and results of surgical treatment and adjuvant chemotherapy, especially when done preoperatively].
    Archiv fur Geschwulstforschung, 1988, Volume: 58, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Cyclophosphamide; Doxor

1988