tegafur has been researched along with Cancer of Rectum in 316 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to determine the maximum tolerated dose, recommended dose and dose-limiting toxicities of irinotecan (CPT-11) plus S-1 in advanced colorectal cancer." | 9.14 | A phase I study of combination therapy with S-1 and irinotecan (CPT-11) in patients with advanced colorectal cancer. ( Akaike, M; Morinaga, S; Shiozawa, M; Sugano, N; Sugimasa, Y; Tsuchida, K, 2009) |
| "The aim of this study was to evaluate the efficacy of preoperative radiation therapy for resectable rectal adenocarcinoma (T3-T4) when delivered in combination with chemotherapy (oral tegafur-uracil modulated with leucovorin)." | 9.10 | Efficacy of preoperative radiation therapy for resectable rectal adenocarcinoma when combined with oral tegafur-uracil modulated with leucovorin: results from a phase II study. ( Batlle, JF; Carpeño, Jde C; García, AG; Grande, AG; Juberías, AM; Olivar, LM; Piñeiro, EH; Sánchez Santos, ME; Uzcudun, AE; Velasco, JC, 2002) |
| "A 42-year-old woman with reversible splenial lesion syndrome (RESLES) and rectal adenocarcinoma presented with sudden-onset delirium after the sixth cycle of her chemotherapy drug, oral tegafur-uracil (300 mg/m/day, days 1-14, with treatment cycle repeated every 21 days)." | 7.96 | Reversible Splenial Lesion Syndrome (RESLES) After Chemotherapy of Oral Tegafur-uracil in a Female With Locally Rectal Adenocarcinoma. ( Bi, QQ; Chen, YJ; Ge, YX; Lin, YY, 2020) |
| " In a previous study, the authors demonstrated that the combination of uracil and tegafur (UFT) with leucovorin (LV) was active and well tolerated in patients with advanced colorectal carcinoma (ACC)." | 7.69 | Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group. ( Colmenarejo, A; de Castro, J; de la Gándara, I; Espinosa, E; Espinosa, J; Feliu, J; Fernández, Y; García Girón, C; González Barón, M; Jalón, JI, 1997) |
| "The aim of this study was to determine the maximum tolerated dose, recommended dose and dose-limiting toxicities of irinotecan (CPT-11) plus S-1 in advanced colorectal cancer." | 5.14 | A phase I study of combination therapy with S-1 and irinotecan (CPT-11) in patients with advanced colorectal cancer. ( Akaike, M; Morinaga, S; Shiozawa, M; Sugano, N; Sugimasa, Y; Tsuchida, K, 2009) |
| "Preoperative tegafur suppositories are associated with low toxicity and may lead to anal sphincter-sparing surgery with acceptable postoperative complications and favorable local and distal control." | 5.12 | Preoperative tegafur suppositories for resectable rectal cancer: phase II trial. ( Hamada, K; Izumi, M; Kashiwabara, K; Kawate, S; Nakamura, S; Ogawa, T; Ohwada, S; Sato, Y, 2006) |
| "The aim of this study was to evaluate the efficacy of preoperative radiation therapy for resectable rectal adenocarcinoma (T3-T4) when delivered in combination with chemotherapy (oral tegafur-uracil modulated with leucovorin)." | 5.10 | Efficacy of preoperative radiation therapy for resectable rectal adenocarcinoma when combined with oral tegafur-uracil modulated with leucovorin: results from a phase II study. ( Batlle, JF; Carpeño, Jde C; García, AG; Grande, AG; Juberías, AM; Olivar, LM; Piñeiro, EH; Sánchez Santos, ME; Uzcudun, AE; Velasco, JC, 2002) |
| "In this prospective randomized study the effect of oral Ftorafur was compared with that of intravenous 5-fluorouracil in patients with advanced adenocarcinoma of the stomach, colon or rectum." | 5.06 | Comparison of oral ftorafur and intravenous 5-fluorouracil in patients with advanced cancer of the stomach, colon or rectum. ( Bjerkeset, T; Fjøsne, HE, 1986) |
| "A 42-year-old woman with reversible splenial lesion syndrome (RESLES) and rectal adenocarcinoma presented with sudden-onset delirium after the sixth cycle of her chemotherapy drug, oral tegafur-uracil (300 mg/m/day, days 1-14, with treatment cycle repeated every 21 days)." | 3.96 | Reversible Splenial Lesion Syndrome (RESLES) After Chemotherapy of Oral Tegafur-uracil in a Female With Locally Rectal Adenocarcinoma. ( Bi, QQ; Chen, YJ; Ge, YX; Lin, YY, 2020) |
| "Patients with primary, resectable, T2 or T3, N0-N1 adenocarcinoma in the lower 6 cm of the rectum were given chemoradiotherapy (60 Gy in 30 fractions to tumour, 50 Gy in 30 fractions to elective lymph node volumes, 5 Gy endorectal brachytherapy boost, and oral tegafur-uracil 300 mg/m(2)) every weekday for 6 weeks." | 3.81 | High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study. ( Appelt, AL; Harling, H; Jakobsen, A; Jensen, FS; Jensen, LH; Jørgensen, JC; Lindebjerg, J; Pløen, J; Rafaelsen, SR, 2015) |
| " We describe a patient with acute abdominal symptoms and evidence of PCI with PBG under cetuximab, oxaliplatin, tegafur-uracil and folinic acid chemotherapy for metastatic adenocarcinoma of the rectosigmoid junction." | 3.76 | Gas in portal circulation and pneumatosis cystoides intestinalis during chemotherapy for advanced rectal cancer. ( Astone, A; Barone, C; Chiarla, C; Clemente, G; De Rose, AM; Giovannini, I; Nuzzo, G, 2010) |
| " In a previous study, the authors demonstrated that the combination of uracil and tegafur (UFT) with leucovorin (LV) was active and well tolerated in patients with advanced colorectal carcinoma (ACC)." | 3.69 | Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group. ( Colmenarejo, A; de Castro, J; de la Gándara, I; Espinosa, E; Espinosa, J; Feliu, J; Fernández, Y; García Girón, C; González Barón, M; Jalón, JI, 1997) |
| "A total of 65 patients with advanced colorectal or breast cancer were given oral tegafur in the phase I study." | 3.66 | Phase I-II studies of oral tegafur (ftorafur). ( Ansfield, FJ; Kallas, GJ; Singson, JP, 1983) |
| "Patients aged 20-80 with stage II/III rectal cancer undergoing curative surgery without preoperative therapy were randomly assigned to receive UFT (500-600 mg/day on days 1-5, followed by 2 days rest) or S-1 (80-120 mg/day on days 1-28, followed by 14 days rest) for 1 year." | 2.82 | A randomized phase III trial comparing S-1 versus UFT as adjuvant chemotherapy for stage II/III rectal cancer (JFMC35-C1: ACTS-RC). ( Baba, H; Emi, Y; Hamada, C; Ikejiri, K; Kakeji, Y; Kotake, M; Maeda, K; Maehara, Y; Matsuda, C; Matsuda, H; Munemoto, Y; Murata, A; Oki, E; Saji, S; Sasaki, K; Suenaga, T; Yoshida, K, 2016) |
| "Irinotecan was administered on days 1, 8, 22, and 29." | 2.82 | A multicenter phase I study of preoperative chemoradiotherapy with S-1 and irinotecan for locally advanced lower rectal cancer (SAMRAI-1). ( Baba, H; Hayakawa, K; Hiraoka, M; Ikushima, H; Kamikonya, N; Kato, D; Nemoto-Murofushi, K; Noda, M; Oya, M; Oya, N; Sakai, Y; Sato, T; Shimada, M; Takeuchi, M; Tomita, N; Watanabe, M; Watanabe, T, 2016) |
| "The purpose of this phase I study of the dose escalation of oxaliplatin in combination with oral S-1 and pelvic radiation preoperatively for poor-risk lower rectal cancer was to determine the dose-limiting toxicity (DLT) and recommended dose of oxaliplatin." | 2.80 | A phase I trial of preoperative S-1 in combination with oxaliplatin and pelvic radiation for lower rectal cancer with T4 and lateral pelvic lymph node metastasis. ( Fujita, S; Hamaguchi, T; Ito, Y; Kinugasa, Y; Moriya, Y; Noura, S; Ohue, M; Saito, N; Sakai, D; Shimada, Y, 2015) |
| " In both arms, S-1 dosing (oral) will be based on body surface area (80 mg/day for body surface area<1." | 2.80 | Randomized phase II study of S-1 dosing schedule for resected colorectal cancer. ( Doki, Y; Hasegawa, J; Hata, T; Ikeda, M; Ikenaga, M; Kato, T; Matsuda, C; Mizushima, T; Mori, M; Murata, K; Nakata, K; Nezu, R; Nishimura, J; Ohue, M; Satoh, T; Sekimoto, M; Shingai, T; Takemasa, I; Uemura, M; Yamamoto, H, 2015) |
| "Patients with clinical stage II or III rectal cancer were treated with radiotherapy of 44 Gy in 22 fractions." | 2.79 | Celecoxib plus chemoradiotherapy for locally advanced rectal cancer: a phase II TCOG study. ( Chen, HC; Chen, HH; Chen, WT; Chien, CR; Hsiao, CF; Lee, HH; Lin, TC; Lin, TY; Liu, TW; Wang, LW, 2014) |
| " In the present study we estimated radiation dose-response curves for various grades of tumor regression after preoperative CRT." | 2.78 | Radiation dose-response model for locally advanced rectal cancer after preoperative chemoradiation therapy. ( Appelt, AL; Bentzen, SM; Jakobsen, A; Pløen, J; Vogelius, IR, 2013) |
| "Locally advanced rectal cancer represents a major therapeutic challenge." | 2.77 | Dose-effect relationship in chemoradiotherapy for locally advanced rectal cancer: a randomized trial comparing two radiation doses. ( Appelt, A; Jakobsen, A; Lindebjerg, J; Ploen, J; Rafaelsen, SR; Vuong, T, 2012) |
| "Irinotecan (80 mg/m2) was infused on Days 1, 8, 22, and 29." | 2.76 | A Phase II trial of neoadjuvant preoperative chemoradiotherapy with S-1 plus irinotecan and radiation in patients with locally advanced rectal cancer: clinical feasibility and response rate. ( Hatate, K; Hayakawa, K; Ihara, A; Koizumi, W; Naito, M; Nakamura, T; Okayasu, I; Onosato, W; Ozawa, H; Sato, T; Watanabe, M; Yamashita, K, 2011) |
| " Major adverse effects were hematological toxicities, gastrointestinal disturbance, neurosensory toxicity." | 2.76 | [Efficacy and side effects of combination therapy of oxaliplatin and S-1 for colorectal cancer]. ( Jin, ZM; Zhu, QC, 2011) |
| "A total of 760 patients with colon cancer and 669 patients with rectal cancer were entered into this randomized clinical trial (RCT)." | 2.71 | Randomized controlled trial of the efficacy of adjuvant immunochemotherapy and adjuvant chemotherapy for colorectal cancer, using different combinations of the intracutaneous streptococcal preparation OK-432 and the oral pyrimidines 1-hexylcarbamoyl-5-flu ( Hojyo, K; Isomoto, H; Kato, T; Kodaira, S; Kunii, Y; Kunitomo, K; Niimoto, M; Nishida, O; Ohashi, Y; Takahashi, T; Tominaga, T; Watanabe, M; Yasutomi, M, 2004) |
| "In resectable rectal cancer, if preoperative treatment is considered, this approach can be an option." | 2.71 | Preoperative uracil, tegafur, and concomitant radiotherapy in operable rectal cancer: a phase II multicenter study with 3 years' follow-Up. ( Almenar, D; Aparicio, J; Arlandis, F; Bosch, C; Campos, J; Campos, JM; Climent, MA; Estevan, R; Fernández-Martos, C; Garcera, S; Hernandez, A; Maestu, I; Mengual, JL; Puchades, R; Richart, JM; Tormo, A; Torregrosa, M; Uribe, N; Vicent, JM; Viciano, V, 2004) |
| " dosing without requiring any i." | 2.70 | Phase I study of oral uracil and Tegafur plus leucovorin and pelvic radiation in patients with recurrent rectal cancer. ( Dunst, J; Engenhart-Cabillic, R; Hess, CF; Hoffmann, W; Reese, T; Schiebe, ME; Schmidberger, H; Wenz, F, 2002) |
| " cis-Diaminedichloroplatinum (cisplatin) has been reported to immunomodulate, especially when used in low dose in combination with 5-Fluorouracil (5-FU)." | 2.70 | Immunomodulatory effects of low dose cis-Diaminedichloroplatinum (cisplatin) combined with UFT and PSK in patients with advanced colorectal cancer. ( Ando, K; Fukuzawa, M; Kanou, H; Kimura, T; Nagata, Y; Nezu, T; Shibata, M; Takekawa, M, 2002) |
| " We administered pharmacokinetic modulating chemotherapy, based on the concept that the benefit of a continuous venous 5-fluorouracil (5FU) infusion can be potentiated by low-dose oral UFT, a combination of 1-(2-tetrahydrofuryl)-5-fluorouracil (tegafur) and uracil at a molar ratio of 1:4." | 2.69 | Effects of pharmacokinetic modulating chemotherapy using oral UFT and continuous venous 5FU infusion on the prognosis of irradiated rectal carcinomas with p53 overexpression. ( Kotera, H; Kusunoki, M; Noda, M; Yamamura, T; Yanagi, H, 1998) |
| " Protracted infusional 5-FU has been associated with decreased tumor recurrence and improved survival when combined with postoperative adjuvant pelvic radiotherapy." | 2.69 | Postoperative radiation therapy for rectal cancer combined with UFT/leucovorin. ( Haller, DG; Minsky, BD; Rosenthal, DI; Saltz, L; Semple, D, 2000) |
| " Based on the feasibility and adverse reactions, the dosage of UFT should be set according to the body surface area at 375-425 mg/m2/day." | 2.69 | [Optimal dosage of UFT in a weekday-on/weekend-off schedule as a postoperative adjuvant chemotherapy for colorectal cancer]. ( Fukushima, T; Hiki, Y; Kumada, K; Makuuchi, H; Mitomi, T; Nagasaki, H; Nishiyama, K; Ohki, S; Otani, Y; Sadahiro, S; Shimada, H; Takahashi, T; Takemiya, S; Tsukikawa, S; Yamaguchi, S; Yamamura, T, 2000) |
| "For the local recurrence of rectal cancer, it was observed in Dukes C and cases of relative curative resection." | 2.68 | [Cooperative study of surgical adjuvant chemotherapy for colorectal cancer. Cooperative Study Group of Surgical Adjuvant Chemotherapy for Colorectal Cancer in Japan]. ( Kikuchi, K; Kunii, Y, 1995) |
| "In collaboration with 428 institutions nation-wide, comparative studies on the optimal daily dosage of UFT were carried out for non-curative resection cases of colorectal cancer for two years from January 1984 to December 1985." | 2.67 | [Cooperative Study of Surgical Adjuvant Chemotherapy for Colorectal Cancer (fourth report): five-year results after surgery]. ( Abe, O; Hattori, T; Inokuchi, K; Kikuchi, K; Komi, N; Kondo, T; Maehara, Y; Sugimachi, K; Taguchi, T; Uchino, J, 1993) |
| "Five-year survival was 82." | 2.67 | [Clinical effect of postoperative adjuvant chemotherapy for advanced colorectal cancer--comparisons of between tegafur (FT) and UFT]. ( Gotoda, H; Kinami, Y; Miyazaki, I; Saito, H; Takashima, S; Tomita, F; Yamaguchi, A, 1991) |
| "Patients (1,256 with colon cancer, 1,221 with rectal cancer) were divided into the treatment group (group A) and the control group (surgical resection only, group B)." | 2.66 | [Cooperative study of surgical adjuvant chemotherapy of colorectal carcinoma (second study): a preliminary report. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan]. ( Abe, O; Hattori, T; Inokuchi, K; Kikuchi, K; Kodaira, S; Komi, N; Kondo, T; Ogawa, N; Taguchi, T; Uchino, J, 1989) |
| "The group of research for colorectal cancer treatments-Kajitani-group (chief T." | 2.66 | [Adjuvant chemotherapy of colorectal cancer--results of prospective randomized trials]. ( Hojo, K; Kajitani, T, 1986) |
| "In the colon cancer patients, 5-year survival rates were 88." | 2.66 | [Clinical effect of postoperative adjuvant immunochemotherapy with the FT-207 suppository and PSK in colorectal cancer patients. Colorectal Cancer Chemotherapy Group in Hokuriku]. ( Kinami, Y; Miyazaki, I; Takashima, S, 1988) |
| "The rate of local recidivation in colon cancer resected curatively was higher in ACNU + FT group than in FT only group (p less than 0." | 2.66 | [A cooperative study of surgical adjuvant chemotherapy of colorectal cancer (second report): 3-year survival rate. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan]. ( Abe, O; Hattori, T; Inokuchi, K; Kasai, Y; Kikuchi, K; Komi, N; Kondo, T; Niimoto, M; Ogawa, N; Taguchi, T, 1988) |
| "Oral tegafur and I." | 2.65 | A comparative study of oral tegafur and intravenous 5-fluorouracil in patients with metastatic colorectal cancer. ( Bedikian, AY; Bodey, GP; Karlin, D; Korinek, J; Stroehlein, J, 1983) |
| "With rectal cancer, 5-year survival was 57." | 2.65 | [Evaluation of preoperative administration of N1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) suppository in surgical adjuvant chemotherapy for large bowel cancer]. ( Fujita, H; Kosaka, T; Miyazaki, I; Takashima, S; Ueno, K, 1984) |
| "The patient is alive and well without recurrence for more than 10years after lung resection." | 2.55 | [A Case of Recurrent Rectal Cancer with Adrenal and Lung Metastasis with More than Ten-Year Survival after Surgery]. ( Fuse, T; Katarao, Y; Kimura, Y; Shimizu, Y; Takemura, M; Tanaka, R; Uchiyama, K; Yamamoto, Y, 2017) |
| "Accordingly, we diagnosed fulminant type 1 diabetes." | 2.52 | The development of fulminant type 1 diabetes during chemotherapy for rectal cancer. ( Adachi, J; Gotyo, N; Mimura, M; Watanabe, T, 2015) |
| "Undifferentiated rectal cancer is a rare condition with extremely poor prognosis according to the Japanese literature." | 2.47 | [A case of long-term survival after resection of advanced undifferentiated rectal cancer treated by short-term preoperative chemoradiotherapy and postoperative adjuvant chemotherapy]. ( Hase, K; Hashiguchi, Y; Kajiwara, Y; Mochizuki, H; Naito, Y; Shimazaki, H; Ueno, H, 2011) |
| "UFT (tegafur and uracil) is an oral anticancer drug that has been developed in Japan." | 2.44 | UFT (tegafur and uracil) as postoperative adjuvant chemotherapy for solid tumors (carcinoma of the lung, stomach, colon/rectum, and breast): clinical evidence, mechanism of action, and future direction. ( Tanaka, F, 2007) |
| "Adjuvant therapy of colorectal cancer with oral fluorinated pyrimidines is attractive because of its ease of administration and good tolerability." | 2.42 | Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials. ( Burzykowski, T; Buyse, M; Hamada, C; Ohashi, Y; Piedbois, P; Sakamoto, J, 2004) |
| "Adjuvant radiation therapy for rectal cancer is not widely used in Japan, while chemotherapy is considered the adjuvant treatment of choice." | 2.41 | [Progress in adjuvant therapy for colorectal cancer]. ( Kakeji, Y; Kohnoe, S; Maehara, Y, 2002) |
| "FT suppository for rectal cancer is considered to be safe and effective." | 2.40 | [Moderately differentiated adenocarcinoma of the rectum: a case report of remarkable response to preoperative administration of FT suppository]. ( Anzai, T; Izumi, M; Kawate, S; Morishita, Y; Ohwada, S; Sasaki, A; Tokizawa, N, 1997) |
| "Fifty-six patients with cT2N0M0 rectal cancer who exhibited the following characteristics (an anal verge of ≤8 cm, tumor size of <30 mm, well- or moderately differentiated adenocarcinoma on biopsy) underwent LE following nCRT." | 1.91 | Clinical T2N0 Rectal Cancer Treated with Neoadjuvant Chemoradiotherapy plus Local Excision. ( Chan, LF; Kamei, Y; Miyakita, H; Ogimi, T; Okada, K; Sadahiro, S; Suzuki, T; Yamamoto, S, 2023) |
| " Thirty-two patients developed 54 events of CRT-related adverse events, including only one patient with a grade 3 event (stomatitis)." | 1.62 | Tolerability and safety of adjuvant chemoradiotherapy with S-1 after limited surgery for T1 or T2 lower rectal cancer. ( Doki, Y; Eguchi, H; Kitakaze, M; Miyoshi, N; Mizushima, T; Murata, K; Noura, S; Ohue, M; Takahashi, H; Tei, M; Uemura, M, 2021) |
| "Watchful waiting in patients with rectal cancer with complete clinical response after chemoradiation therapy has gained increased popularity to avoid morbidity and mortality associated with surgery." | 1.56 | Abnormal Neuronal Response to Rectal and Anal Stimuli in Patients Treated for Distal Rectal Cancer With High-Dose Chemoradiotherapy Followed By Watchful Waiting. ( Brock, C; Christensen, P; Gram, M; Haas, S; Krogh, K; Laurberg, S; Lundby, L; Mohr Drewes, A; Møller Faaborg, P, 2020) |
| "Of ypStage III rectal cancer patients who received preoperative RT (5 × 5 Gy) in January 2006-December 2015, those who had ypStage III cancer after preoperative radiation, radical resection, and postoperative chemotherapy were enrolled; excluded patients had ypStage I and II rectal cancer, had double cancer, had synchronous distant metastasis, had local excision, received preoperative chemoradiation, and were lost to follow-up within 1 year after cancer treatment." | 1.51 | Monthly tegafur-uracil maintenance for increasing relapse-free survival in ypStage III rectal cancer patients after preoperative radiotherapy, radical resection, and 12 postoperative chemotherapy cycles: a retrospective study. ( Chen, CJ; Chin, CC; Huang, CY; Huang, WS; Huang, YC; Kuo, YH; Lai, CH, 2019) |
| "A 60s man was diagnosed with rectal cancer and underwent low anterior resection of the rectum." | 1.51 | [A Case of Curatively Resected Locally Recurrent Rectal Mucinous Adenocarcinoma Followed by Preoperative Chemoradiotherapy]. ( Ishida, T; Kajiwara, T; Kamei, T; Karasawa, H; Kohyama, A; Naitoh, T; Ohnuma, S; Sato, K; Suzuki, H; Unno, M; Watanabe, K, 2019) |
| "A total of 118 rectal cancer patients receiving preoperative CRT were enrolled." | 1.51 | Identification of Predictors of Recurrence in Patients with Lower Rectal Cancer Undergoing Neoadjuvant Chemotherapy: A Direct Comparison of Short-Course and Long-Course Chemoradiotherapy. ( Araki, T; Fujikawa, H; Hiro, J; Ide, S; Kusunoki, M; Ohi, M; Okugawa, Y; Saigusa, S; Toiyama, Y; Yamamoto, A; Yasuda, H; Yoshiyama, S, 2019) |
| "We report a case of locally advanced rectal cancer, treated effectively with chemotherapy consisting of mFOLFOX6 combined with radiotherapy." | 1.46 | [A Case of Effective Chemoradiotherapy Using mFOLFOX6 for Locally Advanced Rectal Cancer]. ( Hashimoto, Y; Hirata, Y; Ishizaki, Y; Kitamura, S; Kuga, Y; Miwata, T; Mouri, T, 2017) |
| "A total of 198 patients with rectal cancer underwent preoperative endoscopic assessments after chemoradiotherapy." | 1.46 | Prediction of Pathological Complete Response Using Endoscopic Findings and Outcomes of Patients Who Underwent Watchful Waiting After Chemoradiotherapy for Rectal Cancer. ( Fukayama, M; Hata, K; Ishihara, S; Kawai, K; Kiyomatsu, T; Morikawa, T; Nozawa, H; Watanabe, T, 2017) |
| "The mean recurrence-free survival was 13." | 1.43 | [Adjuvant Systemic Chemotherapy with S-1/Oxaliplatin or mFOLFOX6 after Curative Resection of Distant Metastases in Patients with Colorectal Cancer]. ( Amada, E; Baba, S; Kameyama, N; Mitsuhashi, H; Miyata, R; Tomita, M, 2016) |
| "She was diagnosed with rectal cancer, and bilateral lymph node and pulmonary metastases were detected on computed tomography(CT)." | 1.43 | [A Case of Laparoscopic Surgery for Rectal Cancer with Synchronous Lung Metastases after Chemotherapy]. ( Akasaka, H; Hakamada, K; Ichinohe, D; Jin, H; Miura, T; Morohashi, H; Nagase, H; Okano, K; Sakamoto, Y; Yoshida, E; Yoshida, T, 2016) |
| "5-Fluorouracil-based chemotherapy is considered to be a radiosensitizer; however, conventional short-course radiotherapy combined with chemotherapy is generally thought to not be feasible because of the prevalence of side effects." | 1.42 | Feasibility of modified short-course radiotherapy combined with a chemoradiosensitizer for T3 rectal cancer. ( Beppu, N; Doi, H; Kakuno, A; Kamikonya, N; Matsubara, N; Tomita, N; Yamanaka, N; Yanagi, H, 2015) |
| "Fifty-nine rectal cancer patients were subjected to preoperative CRT." | 1.42 | Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer. ( Eto, S; Higashijima, J; Hotchi, M; Iwata, T; Nakao, T; Nishi, M; Shimada, M; Takasu, C; Teraoku, H; Yoshikawa, K, 2015) |
| "She was diagnosed with rectal cancer via colonoscopy." | 1.42 | [A Case of Locally Advanced Rectal Cancer with a Pathological Complete Response to Preoperative Chemoradiotherapy]. ( Akahoshi, S; Iizaka, M; Murakami, S; Nimura, S; Takeguchi, T, 2015) |
| "We recruited 93 rectal cancer patients who underwent neoadjuvant CRT and radical resection." | 1.40 | CD8+ and FOXP3+ tumor-infiltrating T cells before and after chemoradiotherapy for rectal cancer. ( Hase, K; Hashiguchi, Y; Ishiguro, M; Kajiwara, Y; Kobayashi, H; Sekizawa, A; Shikina, A; Shinto, E; Ueno, H; Yamamoto, J, 2014) |
| "She was diagnosed with advanced lower rectal cancer with multiple liver and pulmonary metastases." | 1.40 | [Induction chemotherapy with S-1/oxaliplatin prevented colostomy in a patient with advanced rectal cancer]. ( Goto, T; Sasaki, K; Shimao, K; Yano, M, 2014) |
| "Rectal cancer was detected up to 13 cm proximal to the anal verge." | 1.40 | [A case of advanced rectal cancer that showed complete response to the addition of XELOX+bevacizumab therapy to preoperative chemoradiotherapy with S-1/CPT-11]. ( Konno, F; Matsumoto, H; Mitsui, K; Namiki, K; Takahashi, T; Yoshida, R, 2014) |
| "Patients with locally advanced rectal cancer (LARC) have a dismal prognosis." | 1.40 | Post-chemoradiation intraoperative electron-beam radiation therapy boost in resected locally advanced rectal cancer: long-term results focused on topographic pattern of locoregional relapse. ( Alvarez, E; Calvo, FA; Del Valle, E; Deutsch, E; Garcia-Alfonso, P; García-Sabrido, JL; Muñoz-Calero, A; Peligros, I; Rivera, S; Rodriguez, M; Serrano, J; Sole, CV; Turégano, F, 2014) |
| "A 60-year-old man with advanced rectal cancer and urinary bladder fistula received preoperative chemoradiotherapy with S-1(120mg/m / 2day)on weekdays and concurrent radiotherapy(65 Gy)." | 1.40 | [A case of a patient with advanced rectal cancer and urinary bladder fistula surviving for 6 years after chemoradiotherapy without surgery]. ( Arakawa, A; Date, K; Kawada, K; Kimura, M; Kuroda, D; Matsushita, H; Nishimura, T; Shimokawa, Y; Soh, M, 2014) |
| "Heterogeneity exists in rectal cancer, and we hypothesized that there are subclones resistant to chemoradiotherapy within the cancer mass." | 1.40 | Chemoradiation provides a physiological selective pressure that increases the expansion of aberrant TP53 tumor variants in residual rectal cancerous regions. ( Ishihara, S; Kazama, S; Murono, K; Nagai, Y; Nishio, K; Sakai, K; Sunami, E; Tanaka, T; Tomida, S; Watanabe, T, 2014) |
| "The number of lymph nodes in rectal cancer was correlated with the response of primary rectal lesions to chemoradiotherapy, and was not associated with patient survival." | 1.40 | Number of Lymph Nodes in Rectal Cancer is Correlated with Response to Preoperative Chemoradiotherapy but is not Associated with Patient Survival. ( Akahane, T; Aoyagi, Y; Fukushima, Y; Hashiguchi, Y; Hayama, T; Horiuchi, A; Ishihara, S; Matsuda, K; Nakamura, K; Nozawa, K; Shimada, R; Watanabe, T; Yamada, H, 2014) |
| "Colorectal cancer associated with Crohn's disease (CD) is increasing in proportion to the number of patients with CD in Japan." | 1.39 | Metachronous, colitis-associated rectal cancer that developed after sporadic adenocarcinoma in an adenoma in a patient with longstanding Crohn's disease: a case report. ( Doki, Y; Haraguchi, N; Hata, T; Mizushima, T; Mori, M; Nakajima, K; Nishimura, J; Takemasa, I; Takeyama, H; Uemura, M; Yamamoto, H, 2013) |
| "We obtained total RNA from residual cancer cells using microdissection from a total of 52 rectal cancer specimens from patients who underwent preoperative CRT." | 1.38 | Prognostic significance of glucose transporter-1 (GLUT1) gene expression in rectal cancer after preoperative chemoradiotherapy. ( Fujikawa, H; Inoue, Y; Kusunoki, M; Matsushita, K; Okugawa, Y; Saigusa, S; Tanaka, K; Toiyama, Y; Uchida, K, 2012) |
| " Adverse effects ≥ grade 2 were observed in 32% of the patients and adverse effects ≥ grade 3 in 15%." | 1.38 | Safety and outcome of chemoradiotherapy in elderly patients with rectal cancer: results from two French tertiary centres. ( Bensadoun, RJ; Hamidou, H; Michel, P; Paillot, B; Roullet, B; Silvain, C; Tougeron, D; Tourani, JM, 2012) |
| "In addition, we found concomitant gastric cancer by gastrointestinal fiberscopy." | 1.38 | [A patient with multiple liver metastases of gastric and rectal cancers after laparoscopic sigmoidectomy who responded completely to S-1 therapy followed by open gastrectomy]. ( Arai, I; Inoue, S; Ohashi, I; Tamura, C; Wakasa, K, 2012) |
| "Abdominoperineal resection+D3 of rectal cancer was performed, followed by chemotherapy with UFT for 28 days, and then partial resection of liver." | 1.37 | [A case of synchronous hepatic and multiple pulmonary metastases from rectal cancer responding completely to UFT therapy after resection of primary and hepatic lesions]. ( Doi, F; Ishikawa, N; Kohro, T; Kusumoto, C; Kusumoto, M; Matsumoto, T; Toyoda, S, 2011) |
| "To observe the local control rate, survival time and side effect of three-dimensional conformal radiation therapy combined with Tegafur for postoperative recurrent rectal carcinoma." | 1.37 | [Effecacy of three-dimensional conformal radiation therapy combined with Tegafur for postoperative recurrent rectal carcinoma]. ( Li, WL; Liu, XH, 2011) |
| "Advanced lower rectal cancer S-1/oxaliplatin (SOX), combined with preoperative chemoradiation (CRT), have fewer adverse events and are considered to be useful." | 1.37 | [Response in a case of advanced rectal cancer treated by chemoradiation with S-1/oxaliplatin]. ( Ishi, Y; Kikuchi, D; Saito, M; Takenoshita, S; Yamada, M, 2011) |
| "Fistulectomy was carried out for anal fistula." | 1.37 | [A case of carcinoma associated with anal fistula resected after preoperative chemoradiotherapy]. ( Ando, J; Endo, Y; Koyama, Y; Nakamura, I; Ohki, S; Sassa, M; Sato, Y; Suzuki, S; Tachibana, K; Takenoshita, S, 2011) |
| "He was diagnosed with double-cancer of the gallbladder and rectum." | 1.37 | [Synchronous double cancer of the gallbladder and rectum successfully treated with S-1 as second-line chemotherapy- a case report]. ( Araki, M; Hasegawa, H; Itoh, M; Kuzushita, N; Mita, E; Mitsuta, C; Nakazuru, S; Ohta, T; Ota, M; Suemura, S; Sueyoshi, Y; Tatsumi, K; Toyama, T; Yoshio, T, 2011) |
| "We report a long-term survival case of rectal cancer that was initially thought unresectable treated with chemoradiotherapy (CRT)." | 1.37 | [A case of long-term survival after curative resection of advanced rectal cancer treated by pre-operative chemoradiotherapy]. ( Kamiya, A; Kawachi, Y; Maruyama, H; Nagano, H; Nakajima, Y; Ohtsukasa, S; Okazaki, S; Takamatsu, S, 2011) |
| "The rectal cancer was in stage III, and the patient selected no adjuvant chemotherapy." | 1.36 | [A case of metachronous multiple lung metastases and intraabdominal lymph node metastases of rectal cancer responding to S-1]. ( Aiki, F; Hattori, A; Kakisaka, T; Kazui, K; Matsuhisa, T, 2010) |
| "In patients with advanced rectal cancer, preoperative chemoradiotherapy is superior to postoperative chemoradiotherapy because of causing less toxicity and achieving higher rates of sphincter preservation and curative resection." | 1.36 | A case of pathological complete response of advanced rectal cancer to preoperative chemoradiotherapy using S-1. ( Hama, T; Horiuchi, T; Ishida, K; Miyagawa, Y; Sakaguchi, S; Shono, Y; Tabuse, K; Tamagawa, K; Tanishima, H; Tsubakihara, H; Tsujimoto, T; Uemura, R, 2010) |
| " His diagnosis was rectal perforation combined with intraperitoneal abscess." | 1.36 | [A case of rectal cancer combined with intraperitoneal abscess responding completely to uracil/tegafur (UFT) plus oral leucovorin (LV) therapy]. ( Hamaya, M; Hojyo, K; Honda, A; Kaneko, H; Kawashima, H; Narabashi, K; Noda, S; Okamoto, N; Onoda, K; Yamada, K; Yokote, K, 2010) |
| " The regimen of pre-op CCRT was a radiation dosage of 45 Gy in 20 fractions and oral tegafur-uracil (UFUR) and leucovorin." | 1.36 | The impact of preoperative chemoradiotherapy on advanced low rectal cancer. ( Chang, SC; Chen, WS; Jiang, JK; Kao, PS; Lee, RC; Liang, WY; Lin, JK; Lin, TC; Wang, HS; Wang, LW; Yang, SH, 2010) |
| "A 42-year-old man with advanced rectal cancer underwent a low anterior resection with TME and pelvic lateral lymph-node and paraaortic lymph-node dissections." | 1.36 | [A long-term disease-free survival case of advanced rectal cancer with massive metastasis to the lateral pelvic and para-aortic lymph nodes]. ( Gotoh, K; Ishikawa, O; Kano, S; Kishi, K; Miyashiro, I; Motoori, M; Noura, S; Ohigashi, H; Ohue, M; Shingai, T; Takahashi, H; Yamada, T; Yano, M, 2010) |
| "We report a case of local recurrent colorectal cancer that has been treated successfully with low-dose oral chemotherapeutic agent." | 1.36 | [A case of local relapsed rectal cancer responding to low-dose S-1]. ( Fujita, S; Ikeda, N; Kanamura, T; Kojima, Y; Nakagawa, K; Ueno, M, 2010) |
| "A treatment of 5-fluorouracil, 500 mg/body per day intravenously, or oral UFT-E (300 mg/m2) with l-leucovorin (75 mg) per day, or oral S-1 (80 mg/m2) per day five days a week, was given during radiotherapy." | 1.35 | [Our experiences of preoperative chemo-radiotherapy for T4 primary rectal cancer]. ( Agata, T; Aoyama, H; Funahashi, M; Hanai, T; Honda, K; Katsuno, H; Koide, Y; Maeda, K; Matsuoka, H; Noro, T; Sato, H; Shiota, M, 2008) |
| "He was diagnosed with lower rectal cancer by colonoscopy and referred to our hospital for therapy." | 1.35 | [Complete response of advanced rectal cancer with combined therapy of S-1 + chemo-radiation plus FOLFIRI--a case report]. ( Akagi, K; Fujita, J; Hata, T; Hayashi, S; Ikeda, K; Kagawa, Y; Kato, H; Kawanishi, K; Kitada, M; Maeda, S; Nomura, M; Oshima, N; Sasaki, T; Shimano, T; Shimizu, J; Takamoto, K; Tsukahara, Y, 2008) |
| "Thirty-three patients with rectal cancer underwent preoperative CRT." | 1.35 | Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy. ( Ioue, Y; Kusunoki, M; Miki, C; Okugawa, Y; Saigusa, S; Tanaka, K; Toiyama, Y; Yokoe, T, 2009) |
| "We report a case of recurrent rectal cancer with multiple lung metastases successfully treated with S-1 and CPT-11 combination chemotherapy." | 1.35 | [A case of recurrent rectal cancer with multiple lung metastases successfully treated with S-1 and CPT-11 combination chemotherapy]. ( Hara, Y; Kawano, T; Maekawa, K; Minami, Y; Ueda, S, 2009) |
| "Sixteen patients with lower advanced rectal cancer received tegafur/uracil/calcium folinate+RT followed by curative resection with lateral lymph node dissection 2-8 weeks later." | 1.35 | [Preoperative chemoradiotherapy for resectable lower rectal cancer]. ( Kamigaki, T; Nakamura, T; Nishimura, H; Sasaki, R; Takase, S; Yamashita, K, 2009) |
| "A treatment of 5-fluorouracil (500 mg/body) with l-leucovorin (100 mg/body) intravenously once a week, or oral S-1 (100 mg/day/body) for four weeks, was given during radiation therapy." | 1.35 | [Assessment of chemoradiation therapy for advanced rectal cancer invaded the pelvic organ]. ( Doi, K; Hirano, Y; Ishihara, A; Kojima, K; Kudo, K; Ochi, T; Ogata, K, 2009) |
| "We describe a case of locally recurrent rectal cancer that was successfully treated with radiation and chemotherapy with S-1; this treatment resulted in long-term survival of the patient with a good performance status." | 1.35 | [A case of locally recurrent rectal cancer responding to radiation and chemotherapy with S-1]. ( Baba, H; Fujiwara, N; Goseki, N; Kuwabara, H; Nakajima, K; Nakamura, H; Tamai, S, 2009) |
| "We strongly suspected a DPD deficiency from the result of urinary pyrimidine analysis." | 1.35 | [A case of dihydropyrimidine dehydrogenase (DPD) deficiency with severe side effects from UFT/Uzel administration]. ( Doi, Y; Endo, Y; Ishizuka, S; Kai, K; Matsumoto, Y; Morikawa, T; Nabeyama, A; Nagahiro, W; Nakashima, A; Nobuhisa, T; Sato, S; Watanabe, T; Yamada, T; Yoshida, K, 2008) |
| "Here, we report a case of metastatic rectal cancer showing a complete response (CR) to cycle 4 in FOLFIRI regimen, while maintaining a CR status for over 11 months and good QOL, as a result of chemotherapy with 4 cycles of FOLFIRI followed by UFT." | 1.34 | [A case of metastatic rectal cancer showing a sustained complete response to chemotherapy with FOLFIRI followed by UFT]. ( Baba, K; Matsuda, M; Tashima, R; Yamashita, Y; Yokoyama, S, 2007) |
| "We report a case of advanced rectal cancer successfully treated with a combination of S-1 and CPT-11 as neoadjuvant chemotherapy." | 1.34 | [Neoadjuvant chemotherapy with combination of S-1 and CPT-11 in advanced rectal cancer - a case report]. ( Han, I; Hatori, S; Iwasaki, H; Murakami, H; Suzuki, M; Takanashi, Y; Yamakawa, M, 2007) |
| " The patient was treated with S-1 combined with CPT-11." | 1.34 | [An elderly patient with recurrent rectal cancer successfully responded to S-1 combined with CPT-11]. ( Doi, M; Egawa, T; Hayashi, S; Ito, Y; Kitano, M; Nagashima, A; Sekine, K; Shimizu, M; Yoshii, H, 2007) |
| " 5-FU serum concentrations were higher at night time and the peak concentration of 5-FU was obtained at 3 a." | 1.33 | [Pharmacokinetic modulating chemotherapy for rectal carcinoma metastases to the liver and lung--a case report]. ( Hatakeyama, K; Muneoka, K; Shirai, Y; Wakai, T; Yokoyama, N, 2005) |
| "A 59-year-old male patient with rectal cancer 2 cm in diameter (T2) at the peritoneal reflection with suspicious left lateral node metastasis was treated with 400 mg of preoperative oral uracil and tegaful (UFT) for 5 weeks, 5 days a week in combination with concomitant radiotherapy of 45 Gy per 25 fractions for 5 weeks." | 1.33 | Neoadjuvant therapy of rectal cancer using oral tegaful-uracil (UFT) plus concomitant radiotherapy--a case report. ( Arihiro, K; Emi, M; Hironaka, K; Kawabuchi, Y; Ohshita, A; Sakatani, A; Yamaguchi, Y, 2005) |
| "To investigate the effect and feasibility of concurrent radiation and chemotherapy combined with endorectal brachytherapy in T3 rectal cancer with complete pathologic remission as end point." | 1.33 | Preoperative chemoradiation of locally advanced T3 rectal cancer combined with an endorectal boost. ( Bisgaard, C; Hansen, JW; Jakobsen, A; Lindebjerg, J; Mortensen, JP; Rafaelsen, SR, 2006) |
| " The patient was treated with TS-1 combined with CPT-11." | 1.33 | [A case of an increase in resectability with preoperative chemotherapy TS-1 combined with CPT-11 for unresectable rectal cancer in downstaging]. ( Doi, M; Egawa, T; Hayashi, S; Kitano, M; Nagashima, A; Yoshii, H, 2005) |
| "One hundred fifteen patients with rectal cancer were treated with oral 5-fluorouracil or Tegafur with preoperative radiotherapy, surgery, and intraoperative electron beam radiation therapy to identify potential pre- and on-treatment characteristics that might be of prognostic value for disease outcome." | 1.33 | Prognostic factors for disease-free survival in patients with T3-4 or N+ rectal cancer treated with preoperative chemoradiation therapy, surgery, and intraoperative irradiation. ( Alvarez, E; Calvo, FA; Cortés, J; Del Valle, E; Díaz-González, JA; García-Sabrido, JL; Gómez-Espí, M; Muñoz-Jiménez, F, 2006) |
| "Patients with locally advanced rectal cancer (LARC) have a poor prognosis." | 1.33 | [New treatment strategies for patients with primary non-resectable rectal cancer]. ( Baatrup, G; Jensen, HA; Kronborg, O; Pfeiffer, P, 2006) |
| "A sample of 83 rectal cancer patients in Dukes' stages B2 or C who started a chemoradiotherapy treatment followed by surgery, have filled in the EORTC core questionnaire QLQC30 and the colorectal module QLQ-CR38, in three moments during the treatment and follow-up periods: at the beginning of the treatment, at the end of the chemoradiotherapy, and after surgery." | 1.33 | Quality of Life assessment through the EORTC questionnaires of locally advanced rectal cancer patients treated with preoperative chemo-radiotherapy. ( Arias de la Vega, F; Arraras Urdaniz, JI; Manterola Burgaleta, A; Martínez Aguillo, M; Salgado Pascual, E; Vera García, R; Villafranca Iturre, E, 2006) |
| "Tegafur levels were also higher in tumor samples than other sites (mean 3446." | 1.33 | Tegafur and 5-fluorouracil pelvic tissue concentrations in rectal cancer patients receiving preoperative chemoradiation. ( Aldaz, A; Alvarado, A; Arranz, JA; Calvo, FA; de la Mata, D; García, R; Giráldez, J; Serrano, J; Zufía, L, 2006) |
| "We report a rectal cancer case with liver and lung metastases treated successfully with this protocol." | 1.32 | [A case of liver and lung metastases of rectal cancer responding well to 5-FU hepato-arterial infusion (HAI) with combined use of oral UFT]. ( Ebuchi, M; Hasegawa, K; Kato, K; Maruyama, M; Nagahama, T; Shinoura, H; Takashima, I, 2003) |
| "Twenty-five consecutive patients with rectal cancer were included, with tumor stages (c)T(2-4)N(x)M(0), during the period 1997-1999." | 1.32 | 18F-FDG positron emission tomography staging and restaging in rectal cancer treated with preoperative chemoradiation. ( Alvarez, E; Arranz, JA; Calvo, FA; Carreras, JL; Desco, M; Domper, M; Martínez-Lázaro, R; Matute, R, 2004) |
| "The patient was a 61-year-old man with rectal cancer and multiple pulmonary metastases." | 1.32 | [A case of multiple pulmonary metastases from rectal cancer effectively treated by TS-1 and low-dose CDDP therapy]. ( Ishimura, K; Karasawa, Y; Maeta, H; Ushiyama, T; Wakabayashi, H, 2004) |
| "We treated a patient with unresectable rectal cancer with multiple liver, pulmonary and lymph node metastases that responded remarkably to pharmacokinetic modulating chemotherapy (PMC)." | 1.31 | [A case of unresectable rectal cancer with liver and pulmonary metastases that responded remarkably to pharmacokinetic modulating chemotherapy]. ( Chiba, M; Hayashi, K; Inaba, Y; Kamio, Y; Koyama, M; Ohe, S; Watabe, S, 2002) |
| "Diarrhea was the major adverse effect of UFT/LV that made patients reduce dosage." | 1.31 | Oral uracil/ftorafur (UFT) plus leucovorin as first-line chemotherapy and salvage therapy with weekly high-dose 5-fluorouracil/leucovorin for the treatment of metastatic colorectal cancer. ( Chen, JS; Hsu, KC; Tang, R; Wang, JY; Yang, TS, 2002) |
| "We report a case of unresectable rectal cancer in a 53-year-old male treated with chemoradiation." | 1.31 | [Long-term complete response in a case of unresectable rectal cancer following chemoradiation]. ( Musha, N; Oka, K; Saito, H; Sando, N; Sasaki, M; Setu, M; Setu, Y; Sunami, E, 2000) |
| "We report a case of advanced rectal cancer accompanied by unresectable liver metastasis in which remission has been achieved for 7 years." | 1.31 | [A case of advanced rectal cancer with unresectable liver metastasis for which chemotherapy was markedly effective]. ( Baba, H; Kikunaga, H; Matsudo, A; Miura, H; Morisue, A; Nakai, H; Osakabe, Y; Sotome, K; Takao, M, 2000) |
| "Tegafur is a prodrug that is converted to 5-fluorouracil (5-FU) and has been reported to be less toxic and to have a higher therapeutic index." | 1.31 | Phase II study of oral tegafur-uracil and folinic acid as first-line therapy for metastatic colorectal cancer: Taiwan experience. ( Chen, PM; Chiou, TJ; Fan, FS; Hsieh, RK; Hsu, TC; Jiang, JK; Lin, JK; Lin, TC; Liu, JH; Wang, HS; Wang, WS; Yang, SH; Yen, CC, 2000) |
| "A 67-year-old female with rectal cancer and multiple liver metastases underwent low anterior resection by total mesorectal excision (TME), cholecystectomy and hepatic arterial cannulation in June 1995." | 1.31 | [Long survival in a case of unresectable hepatic metastasis from rectal carcinoma treated with second-look hepatectomy plus pharmacokinetic modulating chemotherapy (PMC)]. ( Kusunoki, M; Noda, M; Yamamura, T; Yanagi, H; Yoshikawa, R, 2001) |
| " He was treated postoperatively with arterial infusion pharmacokinetic modulating chemotherapy (PMC) and venous infusion CPT-11 (modified PMC)." | 1.31 | [A case of rectal cancer with multiple liver metastases that responded dramatically to pharmacokinetic modulating chemotherapy/CPT-11 therapy]. ( Dan, T; Kitayama, Y; Kosaka, H; Maeda, S; Matsusaka, S; Okada, T; Tanabe, H; Yamasaki, H, 2002) |
| "for 16 days before excision of rectal cancer." | 1.28 | Leukoencephalopathy induced by tegafur: serial studies of somatosensory evoked potentials and cerebrospinal fluid. ( Hanyu, N; Hayashi, R; Kitahara, A, 1992) |
| "To remove regionally recurrent cancer of the rectum completely, more radical extensive resections were attempted than the conventional ones in 35 patients." | 1.28 | Extensive en bloc resection of regionally recurrent carcinoma of the rectum. ( Iijima, Y; Kotoura, Y; Maetani, S; Nishikawa, T; Shikata, J; Tobe, T; Yamamura, T, 1992) |
| "Influencing factors of recurrence in rectal cancer, such as depth of invasion, ew, vessel invasion (ly, v) and lymph node involvements were improved in the irradiated group, especially in effective cases, as compared with the non-irradiated group." | 1.28 | [Histopathological findings in rectal carcinomas undergoing preoperative irradiation combined with chemotherapy]. ( Takiguchi, N, 1992) |
| "A case of local recurrence of rectal cancer was successfully treated by UFT combined with two-route CDDP chemotherapy under the AT-II induced hypertension." | 1.28 | [A case of local recurrence of rectal cancer successfully treated by UFT combined with two-route CDDP chemotherapy under the AT-II induced hypertension]. ( Ishizawa, T; Iwashige, H; Maenohara, S; Mure, H; Shimazu, H; Takao, S; Yamada, K, 1991) |
| "Five cases of rectal cancer, one male and 4 females, were preoperatively treated with Tegafur suppositories at 1,500 mg per day, for 8 to 21 days (mean, 14 days)." | 1.28 | [Five cases of rectal cancer showing remarkable response to suppository administration of tegafur]. ( Konn, M; Mikami, K; Morita, T; Ono, K; Yamanaka, Y; Yoshiwara, S, 1989) |
| "One case of survived rectal cancer obtained disease-free for about 8 years with this treatment." | 1.27 | [Chemotherapy of gastric and rectal cancers incorporating non-radical irradiation during remission induction. 1]. ( Kai, Y; Kaiyama, H; Kanazawa, Y; Nakano, N; Okata, T; Sasaki, K; Shoji, T; Takeda, T; Tiba, J; Ujie, S, 1984) |
| "CR was observed in one case of breast cancer, and PR in 29 cases." | 1.27 | [Cooperative phase II study of spansule tegafur (SF-SP)]. ( Taguchi, T, 1984) |
| "Three rectal cancer patients with partial response (PR) were obtained by oral administration of 800-1200 mg/day of SF-SP." | 1.27 | [The case studies on oral administration of tegafur encapsulated with slow releasing granule (SF-SP) for three rectal patients]. ( Endo, S; Furukawa, R; Katsumi, S; Mukae, S; Sato, T; Sekine, S; Watanabe, I; Watanabe, S, 1984) |
| "Preoperative total doses of UFT for gastric cancer were 3." | 1.27 | [Effects of preoperative administration of UFT in gastrointestinal cancer]. ( Kagaya, H; Matsuoka, S; Miyata, S; Nagabuchi, E; Sato, Y; Uchino, J; Une, Y; Yakura, Y, 1986) |
| " However, increase in tegafur dosage volume did not correlate with 5-FU levels." | 1.27 | [5-FU concentration in the blood and tissue of patients with gastric and colorectal cancer after administration of UFT or tegafur]. ( Arima, S; Futami, K; Kinashi, M; Shigeta, M; Shimura, H, 1986) |
| "The sensitivity of human colorectal cancer to 5-fluorouracil (5-FU) and its derivatives: 1-(tetrahydro-2-furyl)-5-FU (tegafur) and 1-hexylcarbamoyl-5-FU (HCFU) was determined by in vitro succinate dehydrogenase inhibition (SDI) test and in vivo subrenal capsule (SRC) assay." | 1.27 | [Human colorectal carcinoma is more sensitive to HCFU than 5-FU and tegafur in in vitro and in vivo drug sensitivity tests]. ( Anai, H; Fukuchi, K; Kusumoto, H; Kusumoto, T; Maehara, Y; Miyamoto, K; Sugimachi, K, 1988) |
| "Fifteen patients with stomach cancer and colorectal cancer were orally administered 600 mg of UFT before operation and the concentration of tegafur, 5-fluorouracil (5-FU) and uracil in the tissues and serum were measured by chemical assay." | 1.27 | [The serum and tissue concentrations of tegafur, 5-fluorouracil and uracil in patients with gastric and colorectal cancers after oral administration of UFT]. ( Kikuchi, K; Kunii, Y; Mori, Y; Nitta, A; Saitou, T; Takahashi, N, 1988) |
| "Five patients with colorectal cancer and unresectable synchronous liver metastases have survived for over five years at this writing." | 1.27 | Long-term survivors of colorectal cancer with unresectable hepatic metastases. ( Fujimoto, S; Higuchi, M; Kitsukawa, Y; Miyazaki, M; Okui, K, 1985) |
| "A retrospective study of 37 colorectal cancer patients with synchronous liver metastases was made." | 1.26 | Comparative efficacy of antitumor treatment for liver metastases from colorectal cancer. ( Fujimoto, S; Kitsukawa, Y; Miyazaki, M; Okui, K, 1981) |
| "Eighty-four previously untreated patients with metastatic adenocarcinoma of the large intestine received intravenous ftorafur at a dosage of 2." | 1.26 | Phase II evaluation of ftorafur in previously untreated colorectal cancer: a Southwest Oncology Group Study. ( Buroker, T; Groppe, C; Guy, G; Heilbrun, L; Hoogstraten, B; McCracken, J; Padilla, F; Quagliana, J; Vaitkevicius, VK, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (14.56) | 18.7374 |
| 1990's | 35 (11.08) | 18.2507 |
| 2000's | 108 (34.18) | 29.6817 |
| 2010's | 114 (36.08) | 24.3611 |
| 2020's | 13 (4.11) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, LW | 8 |
| Liu, YS | 3 |
| Jiang, JK | 8 |
| Suzuki, T | 7 |
| Sadahiro, S | 9 |
| Okada, K | 6 |
| Miyakita, H | 2 |
| Ogimi, T | 2 |
| Chan, LF | 1 |
| Kamei, Y | 1 |
| Yamamoto, S | 1 |
| Li, YT | 1 |
| Chang, WH | 1 |
| Miyashita, S | 1 |
| Shimizu, T | 1 |
| Ishizuka, M | 1 |
| Niki, M | 1 |
| Nishi, Y | 1 |
| Shibuya, N | 1 |
| Hachiya, H | 1 |
| Matsumoto, T | 3 |
| Sakuraoka, Y | 1 |
| Shiraki, T | 1 |
| Mori, S | 2 |
| Iso, Y | 1 |
| Irisawa, A | 1 |
| Aoki, T | 3 |
| Abe, S | 2 |
| Kawai, K | 4 |
| Nozawa, H | 2 |
| Sasaki, K | 4 |
| Murono, K | 2 |
| Emoto, S | 1 |
| Yokoyama, Y | 1 |
| Matsuzaki, H | 1 |
| Nagai, Y | 2 |
| Yoshioka, Y | 1 |
| Shinagawa, T | 1 |
| Sonoda, H | 1 |
| Yamamoto, Y | 3 |
| Oba, K | 3 |
| Ishihara, S | 5 |
| Kuo, YH | 1 |
| Lai, CH | 1 |
| Huang, CY | 1 |
| Chen, CJ | 1 |
| Huang, YC | 2 |
| Huang, WS | 1 |
| Chin, CC | 1 |
| Du, YL | 1 |
| Li, N | 1 |
| Deng, WY | 1 |
| Ma, YJ | 1 |
| Yang, XY | 1 |
| Luo, SX | 1 |
| Sato, K | 3 |
| Karasawa, H | 2 |
| Kajiwara, T | 1 |
| Suzuki, H | 1 |
| Kohyama, A | 1 |
| Watanabe, K | 2 |
| Ohnuma, S | 2 |
| Ishida, T | 1 |
| Kamei, T | 1 |
| Naitoh, T | 2 |
| Unno, M | 2 |
| Yang, B | 1 |
| Shan, J | 1 |
| Feng, Y | 1 |
| Dai, N | 1 |
| Li, M | 1 |
| Chen, C | 1 |
| He, S | 1 |
| Wang, G | 1 |
| Xiao, H | 1 |
| Li, C | 1 |
| Wang, D | 1 |
| Kojima, K | 2 |
| Nakamura, T | 7 |
| Sato, T | 6 |
| Watanabe, M | 6 |
| Haas, S | 1 |
| Møller Faaborg, P | 1 |
| Brock, C | 1 |
| Krogh, K | 1 |
| Gram, M | 1 |
| Lundby, L | 1 |
| Mohr Drewes, A | 1 |
| Laurberg, S | 1 |
| Christensen, P | 1 |
| Ge, YX | 1 |
| Lin, YY | 1 |
| Bi, QQ | 1 |
| Chen, YJ | 1 |
| Imano, N | 1 |
| Murakami, Y | 1 |
| Kubo, K | 1 |
| Kawahara, D | 1 |
| Takeuchi, Y | 1 |
| Nishibuchi, I | 1 |
| Kimura, T | 4 |
| Kochi, M | 1 |
| Takakura, Y | 2 |
| Shimizu, W | 1 |
| Egi, H | 2 |
| Uegami, S | 1 |
| Ohge, H | 1 |
| Takahashi, S | 3 |
| Ohdan, H | 1 |
| Nagata, Y | 2 |
| Miwa, K | 3 |
| Oki, E | 4 |
| Enomoto, M | 1 |
| Ihara, K | 1 |
| Ando, K | 4 |
| Fujita, F | 3 |
| Tominaga, M | 1 |
| Nakayama, G | 1 |
| Shimokawa, M | 2 |
| Saeki, H | 2 |
| Baba, H | 6 |
| Mori, M | 7 |
| Akagi, Y | 1 |
| Tei, M | 1 |
| Noura, S | 3 |
| Ohue, M | 5 |
| Kitakaze, M | 1 |
| Takahashi, H | 2 |
| Miyoshi, N | 2 |
| Uemura, M | 6 |
| Mizushima, T | 5 |
| Murata, K | 2 |
| Doki, Y | 6 |
| Eguchi, H | 2 |
| Tanaka, A | 5 |
| Saito, G | 4 |
| Nagase, H | 3 |
| Kuga, Y | 1 |
| Kitamura, S | 1 |
| Mouri, T | 1 |
| Miwata, T | 1 |
| Hirata, Y | 1 |
| Ishizaki, Y | 1 |
| Hashimoto, Y | 1 |
| Nakagawa, R | 1 |
| Inoue, Y | 5 |
| Ohki, T | 1 |
| Kaneko, Y | 1 |
| Maeda, F | 1 |
| Yamamoto, M | 4 |
| Okuno, K | 2 |
| Aoyama, T | 1 |
| Yokoyama, N | 3 |
| Matsuhashi, N | 1 |
| Kunieda, K | 1 |
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| Fukuchi, K | 1 |
| Andersen, E | 1 |
| Pedersen, H | 1 |
| Kameyama, M | 1 |
| Fukuda, I | 1 |
| Hiratsuka, M | 1 |
| Furukawa, H | 1 |
| Imaoka, S | 1 |
| Koyama, H | 1 |
| Kasai, Y | 1 |
| Takahashi, N | 1 |
| Nitta, A | 1 |
| Saitou, T | 1 |
| Sekine, T | 1 |
| Suda, Y | 1 |
| Uehara, T | 1 |
| Takayama, S | 1 |
| Furue, H | 1 |
| Itoh, I | 1 |
| Higuchi, M | 1 |
| Jo, T | 1 |
| Eckhardt, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multi-center Study of Preoperative Intraarterial Chemoembolization Combined With Radiotherpy in the Management of Locally Advanced Rectal Cancer[NCT03601156] | 204 participants (Anticipated) | Interventional | 2014-06-30 | Recruiting | |||
| 1922GCCC: PHASE 2 STUDY OF PEMBROLIZUMAB AND BAVITUXIMAB FOR PROGRESSIVE RECURRENT/METASTATIC SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK[NCT04150900] | Phase 2 | 7 participants (Actual) | Interventional | 2020-01-13 | Active, not recruiting | ||
| A Phase I/II Study of S-1 and Oxaliplatin Combined With Radiation for Preoperative Locally Advanced Rectal Carcinoma. (SHOGUN Trial)[NCT01227239] | Phase 1/Phase 2 | 45 participants (Anticipated) | Interventional | 2010-09-30 | Active, not recruiting | ||
| A Prospective Observational Study of Patients With Rectal Cancer After Concomitant Radiation and Chemotherapy[NCT00952926] | 55 participants (Actual) | Observational | 2009-10-31 | Completed | |||
| DETECT: Defining the Target Volume for Endoluminal Radiation Boosting in Patients With Rectal Cancer[NCT04927897] | 50 participants (Anticipated) | Observational | 2022-08-16 | Recruiting | |||
| Chemotherapy Combined With High-dose Radiotherapy for Low Rectal Cancer Using Magnetic Resonance Guided Radiotherapy Linear Accelerator：A Prospective Phase 2 Trial[NCT05338866] | 58 participants (Anticipated) | Observational | 2022-01-01 | Enrolling by invitation | |||
| A Randomized Controlled Study of Postoperative Adjuvant Chemotherapy of UFT Compared With Surgery Alone in Patients With Dukes C Colorectal Cancer (NSAS-CC)[NCT00152230] | Phase 3 | 900 participants (Anticipated) | Interventional | 1996-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
21 reviews available for tegafur and Cancer of Rectum
| Article | Year |
|---|---|
[A Case of Recurrent Rectal Cancer with Adrenal and Lung Metastasis with More than Ten-Year Survival after Surgery].
Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Chemotherap | 2017 |
The development of fulminant type 1 diabetes during chemotherapy for rectal cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Diabetes Mellitus, Type 1; Diabetic Ketoacido | 2015 |
The role of meta-analysis in cancer clinical trials.
Topics: Clinical Trials as Topic; Colonic Neoplasms; Humans; Meta-Analysis as Topic; Neoplasms; Rectal Neopl | 2009 |
[A case of long-term survival after resection of advanced undifferentiated rectal cancer treated by short-term preoperative chemoradiotherapy and postoperative adjuvant chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Chemotherapy, Adjuvant; | 2011 |
[Progress in adjuvant therapy for colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug A | 2002 |
UFT and oral leucovorin as radiation sensitizers in rectal and other gastrointestinal malignancies.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Gas | 2003 |
Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 2004 |
Commentary on Wang et al., "Pre-operative chemotherapy with oral tegafur-uracil and leucovorin for rectal cancer" (J Surg Oncol 89: 256-263).
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Combined Modalit | 2005 |
An individual patient data meta-analysis of adjuvant therapy with uracil-tegafur (UFT) in patients with curatively resected rectal cancer.
Topics: Adult; Aged; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Male; Middle Aged; Rando | 2007 |
[Adjuvant chemotherapy for colorectal cancer in Japan-current state and problem areas].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colonic Neopla | 2007 |
UFT (tegafur and uracil) as postoperative adjuvant chemotherapy for solid tumors (carcinoma of the lung, stomach, colon/rectum, and breast): clinical evidence, mechanism of action, and future direction.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Colonic Ne | 2007 |
UFT (tegafur-uracil) in rectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Humans; Rectal Neoplasms; | 2008 |
Chemotherapy in alimentary tract malignomas.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Cytarabine; Doxor | 1981 |
Regional and systemic chemotherapy for advanced colorectal cancer. A review.
Topics: Antineoplastic Agents; Aspartic Acid; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; D | 1983 |
Primary linitis plastica of the rectum: report of four cases and review of the literature.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease- | 1996 |
[Moderately differentiated adenocarcinoma of the rectum: a case report of remarkable response to preoperative administration of FT suppository].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Colonoscopy; Combined Modality Therapy; Humans; Mal | 1997 |
Current and future directions in adjuvant combined-modality therapy of rectal cancer.
Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Combinations | 1997 |
[Chemoradiation for rectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Autonomic Pathways; Drug Administration Schedule; Fl | 1997 |
[Conceptual changes in cancer chemotherapy--biochemical modulation of 5-FU].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; | 2000 |
Adrenalectomy for solitary adrenal metastasis from colorectal carcinoma.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy | 2000 |
Potentiation of antimetabolite action by alkylating agents.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brea | 1985 |
86 trials available for tegafur and Cancer of Rectum
| Article | Year |
|---|---|
Preoperative chemoradiotherapy using tegafur/uracil, oral leucovorin, and irinotecan (TEGAFIRI) followed by oxaliplatin-based chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: the study protocol for a phase II trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Clinical Trials, Phase II as Topi | 2023 |
Randomized phase II study comparing the efficacy and safety of SOX versus mFOLFOX6 as neoadjuvant chemotherapy without radiotherapy for locally advanced rectal cancer (KSCC1301).
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 2021 |
Efficacy and short-term outcomes of preoperative chemoradiotherapy with intermittent oral tegafur-uracil plus leucovorin in Japanese rectal cancer patients: a single center experience retrospective analysis.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem | 2017 |
Randomized phase III trial comparing surgery alone to UFT + PSK for stage II rectal cancer (JFMC38 trial).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Female; Humans; Male; M | 2018 |
Effect of lateral lymph node dissection for mid and low rectal cancer: An ad-hoc analysis of the ACTS-RC (JFMC35-C1) randomized clinical trial.
Topics: Abdomen; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemotherapy, Adjuvant; Colonoscopy; | 2019 |
Celecoxib plus chemoradiotherapy for locally advanced rectal cancer: a phase II TCOG study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Chemoradioth | 2014 |
A phase I trial of preoperative S-1 in combination with oxaliplatin and pelvic radiation for lower rectal cancer with T4 and lateral pelvic lymph node metastasis.
Topics: Adenocarcinoma; Adult; Aged; Alanine Transaminase; Antineoplastic Combined Chemotherapy Protocols; A | 2015 |
Neoadjuvant chemoradiation therapy using concurrent S-1 and irinotecan in rectal cancer: impact on long-term clinical outcomes and prognostic factors.
Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Analysis of Variance; Antineoplastic Combined Chemo | 2014 |
Long-term results of a randomized trial in locally advanced rectal cancer: no benefit from adding a brachytherapy boost.
Topics: Adult; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Chemoradioth | 2014 |
Phase I trial of neoadjuvant preoperative chemotherapy with S-1, oxaliplatin, and bevacizumab plus radiation in patients with locally advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Chemoradio | 2015 |
Phase II study of preoperative concurrent chemoradiotherapy with S-1 plus bevacizumab for locally advanced resectable rectal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy | 2015 |
A phase I dose escalation study of oxaliplatin plus oral S-1 and pelvic radiation in patients with locally advanced rectal cancer (SHOGUN trial).
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Drug | 2015 |
[Immediate results of combined therapy for local recurrences of rectal cancer].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Ch | 2015 |
Randomized phase II study of S-1 dosing schedule for resected colorectal cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplasti | 2015 |
A Randomized Phase 2 Study of Neoadjuvant Chemoradiaton Therapy With 5-Fluorouracil/Leucovorin or Irinotecan/S-1 in Patients With Locally Advanced Rectal Cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradi | 2015 |
A randomized phase III trial comparing S-1 versus UFT as adjuvant chemotherapy for stage II/III rectal cancer (JFMC35-C1: ACTS-RC).
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva | 2016 |
A multicenter phase I study of preoperative chemoradiotherapy with S-1 and irinotecan for locally advanced lower rectal cancer (SAMRAI-1).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy; Diarrh | 2016 |
Pre-operative chemoradiotherapy with UFT and Leucovorin in patients with advanced rectal cancer: a phase II study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb | 2008 |
Cost-effectiveness of adjuvant chemotherapy with uracil-tegafur for curatively resected stage III rectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Diges | 2008 |
A phase I study of combination therapy with S-1 and irinotecan (CPT-11) in patients with advanced colorectal cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Col | 2009 |
Phase II study of preoperative chemoradiotherapy (CRT) with irinotecan plus S-1 in locally advanced rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy | 2010 |
Phase I study of preoperative chemoradiation with s-1 and oxaliplatin in patients with locally advanced resectable rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera | 2011 |
A Phase II trial of neoadjuvant preoperative chemoradiotherapy with S-1 plus irinotecan and radiation in patients with locally advanced rectal cancer: clinical feasibility and response rate.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2011 |
Phase II study of preoperative radiation plus concurrent daily tegafur-uracil (UFT) with leucovorin for locally advanced rectal cancer.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Pro | 2011 |
[Efficacy and side effects of combination therapy of oxaliplatin and S-1 for colorectal cancer].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antineoplastic Combined Chemotherapy Protocols; Colo | 2011 |
Phase I/II study of preoperative concurrent chemoradiotherapy with S-1 for locally advanced, resectable rectal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy; | 2011 |
High-dose radiotherapy (60 Gy) with oral UFT/folinic acid and escalating doses of oxaliplatin in patients with non-resectable locally advanced rectal cancer (LARC): a phase I trial.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Feas | 2012 |
A phase I trial of S-1 with concurrent radiotherapy in patients with locally recurrent rectal cancer.
Topics: Aged; Combined Modality Therapy; Drug Combinations; Female; Humans; Male; Maximum Tolerated Dose; Mi | 2013 |
Dose-effect relationship in chemoradiotherapy for locally advanced rectal cancer: a randomized trial comparing two radiation doses.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brachytherapy; Denmark; Dose-Response Relationship, Ra | 2012 |
Radiation dose-response model for locally advanced rectal cancer after preoperative chemoradiation therapy.
Topics: Adenocarcinoma; Adult; Aged; Brachytherapy; Chemoradiotherapy; Dose-Response Relationship, Radiation | 2013 |
Phase II study of preoperative chemoradiation with S-1 plus oxaliplatin in patients with locally advanced rectal cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemor | 2013 |
Health-related quality of life during postoperative chemoradiotherapy with oral uracil-tegafur and leucovorin in rectal cancer patients.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemot | 2013 |
Prospective feasibility study to evaluate neoadjuvant-synchronous S-1 + RT for locally advanced rectal cancer: a multicenter phase II trial (UMIN ID: 03396).
Topics: Antimetabolites, Antineoplastic; Chemoradiotherapy; Clinical Protocols; Drug Combinations; Feasibili | 2013 |
Efficacy of preoperative radiation therapy for resectable rectal adenocarcinoma when combined with oral tegafur-uracil modulated with leucovorin: results from a phase II study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 2002 |
Phase I study of oral uracil and Tegafur plus leucovorin and pelvic radiation in patients with recurrent rectal cancer.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therap | 2002 |
[Tegafur--preoperative treatment with tegafur suppositories for rectal cancer].
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Dihydrourac | 2003 |
[Preoperative chemoradiotherapy for locally advanced rectal cancer].
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colectomy; | 2003 |
Randomized controlled trial of the efficacy of adjuvant immunochemotherapy and adjuvant chemotherapy for colorectal cancer, using different combinations of the intracutaneous streptococcal preparation OK-432 and the oral pyrimidines 1-hexylcarbamoyl-5-flu
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 2004 |
Preoperative uracil, tegafur, and concomitant radiotherapy in operable rectal cancer: a phase II multicenter study with 3 years' follow-Up.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb | 2004 |
A phase I study of oral UFT given concomitantly with standard preoperative radiotherapy for rectal cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; C | 2004 |
[Multicenter comparative study of the recurrence-inhibitory effect of oral fluoropyrimidine drugs in patients with colorectal cancer following curative resection].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Pr | 2005 |
High-dose radiotherapy and concurrent UFT plus l-leucovorin in locally advanced rectal cancer: a phase I trial.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic | 2005 |
[Clinical evaluation of chemotherapy with irinotecan (CPT-11), l-leucovorin (l-LV), 5-fluorouracil (5-FU), and UFT for metastatic or recurrent colorectal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug A | 2005 |
Adjuvant chemotherapy with uracil-tegafur for pathological stage III rectal cancer after mesorectal excision with selective lateral pelvic lymphadenectomy: a multicenter randomized controlled trial.
Topics: Adult; Aged; Alanine Transaminase; Antineoplastic Combined Chemotherapy Protocols; Bilirubin; Chemot | 2006 |
[A randomized controlled trial to evaluate the effect of adjuvant oral fluoropyrimidine derivative therapy after curative resection for stage II/III rectal cancer-adjuvant chemotherapy trial of S-1 for rectal cancer (ACTS-RC):].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv | 2006 |
Preoperative tegafur suppositories for resectable rectal cancer: phase II trial.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Humans; Male; Middl | 2006 |
Phase I trial of neoadjuvant preoperative chemotherapy with S-1 and irinotecan plus radiation in patients with locally advanced rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug C | 2007 |
Preoperative chemoradiotherapy for rectal cancer: randomized trial comparing oral uracil and tegafur and oral leucovorin vs. intravenous 5-fluorouracil and leucovorin.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2008 |
A COX-2 inhibitor combined with chemoradiation of locally advanced rectal cancer: a phase II trial.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cardiovascular | 2008 |
Long-term results of a phase II trial of high-dose radiotherapy (60 Gy) and UFT/l-leucovorin in patients with non-resectable locally advanced rectal cancer (LARC).
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Comb | 2008 |
Phase I trial of neoadjuvant concurrent chemoradiotherapy with S-1 and weekly irinotecan in locally advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy | 2008 |
A comparative study of oral tegafur and intravenous 5-fluorouracil in patients with metastatic colorectal cancer.
Topics: Administration, Oral; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Injections, | 1983 |
[Evaluation of preoperative administration of N1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) suppository in surgical adjuvant chemotherapy for large bowel cancer].
Topics: Adult; Colonic Neoplasms; Colostomy; Female; Fluorouracil; Humans; Male; Middle Aged; Preoperative C | 1984 |
Methyl-CCNU and ftorafur in treatment of rectosigmoidal tumors and ftorafur capsules in treatment of colorectal tumors.
Topics: Capsules; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Huma | 1981 |
[Cooperative study of surgical adjuvant chemotherapy for colorectal cancer. Cooperative Study Group of Surgical Adjuvant Chemotherapy for Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Admi | 1995 |
[Neoadjuvant chemotherapy with tegafur suppository for rectal cancer--effects of tegafur on nuclear DNA content of cancer cells--Tochigi Colorectal Cancer Study Group].
Topics: Aged; Cell Cycle; Chemotherapy, Adjuvant; DNA, Neoplasm; Drug Administration Schedule; Female; Flow | 1995 |
Tegafur-uracil (UFT) plus folinic acid in advanced rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Humans; L | 1994 |
[Cooperative Study of Surgical Adjuvant Chemotherapy for Colorectal Cancer (third report): five-year results after surgery].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Coloni | 1993 |
[Cooperative Study of Surgical Adjuvant Chemotherapy for Colorectal Cancer (fourth report): five-year results after surgery].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Admi | 1993 |
[Low-dose cisplatin added to continuous infusion of 5-fluorouracil or oral administration of UFT for inoperable advanced or recurrent colorectal cancer].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Coloni | 1997 |
Postsurgical sequential methotrexate, fluorouracil, and leucovorin for advanced colorectal carcinoma: a preliminary study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Dis | 1997 |
Postoperative adjuvant chemotherapy with mitomycin C and UFT for rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Combinatio | 1997 |
Preoperative combined oral UFT plus leucovorin and radiation therapy for rectal cancer.
Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Combinati | 1997 |
[Adjuvant chemotherapy with UFT or UFT with OK-432 to patients with gastric and colorectal cancer. Kanto Adjuvant Study Group].
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colo | 1998 |
Effects of pharmacokinetic modulating chemotherapy using oral UFT and continuous venous 5FU infusion on the prognosis of irradiated rectal carcinomas with p53 overexpression.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, | 1998 |
[Clinical evaluation of S-1, a new anticancer agent, in patients with advanced gastrointestinal cancer. S-1 Cooperative Gastrointestinal Study Group].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Administration Schedu | 1999 |
UFT plus calcium folinate plus radiotherapy for recurrent rectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Follow-Up Studies; Humans; Leucovorin; Neoplasm Recu | 1999 |
Preoperative UFT and calcium folinate and radiotherapy in rectal cancer.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Drug Therapy, Combination; Follow-Up Stu | 1999 |
Phase II study of radiochemotherapy with UFT and low-dose oral leucovorin in patients with unresectable rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antidotes; Antimetabolites, Antineoplastic; Diarrhea; Disease-Free S | 1999 |
Phase I study of preoperative oral uracil and tegafur plus leucovorin and radiation therapy in rectal cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality | 2000 |
A phase I study. Preoperative UFT/leucovorin and radiation therapy in rectal cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adj | 2000 |
Postoperative radiation therapy for rectal cancer combined with UFT/leucovorin.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combin | 2000 |
[Optimal dosage of UFT in a weekday-on/weekend-off schedule as a postoperative adjuvant chemotherapy for colorectal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration | 2000 |
Immunomodulatory effects of low dose cis-Diaminedichloroplatinum (cisplatin) combined with UFT and PSK in patients with advanced colorectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Combined Modalit | 2002 |
Phase II trial of ftorafur with mitomycin C versus ftorafur with methyl-CCNU in untreated colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Drug Evaluation; Drug Ther | 1978 |
[Multicenter cooperative study of pre- and post-operative adjuvant chemotherapy in the treatment of colorectal cancer. North Kyushu Co-operative Study Group for Cancer Chemotherapy].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Coloni | 1992 |
[Clinical effect of postoperative adjuvant chemotherapy for advanced colorectal cancer--comparisons of between tegafur (FT) and UFT].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 1991 |
[Cooperative study of surgical adjuvant chemotherapy of colorectal carcinoma (second study): a preliminary report. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Drug A | 1989 |
[Cooperative study of surgical adjuvant chemotherapy of colorectal carcinoma (second study): 3-year survival after surgery of non-curatively resected patients. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Drug A | 1989 |
Comparison of oral ftorafur and intravenous 5-fluorouracil in patients with advanced cancer of the stomach, colon or rectum.
Topics: Actuarial Analysis; Adenocarcinoma; Aged; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Mid | 1986 |
[Adjuvant chemotherapy of colorectal cancer--results of prospective randomized trials].
Topics: Administration, Rectal; Adult; Aged; Colonic Neoplasms; Drug Administration Schedule; Female; Humans | 1986 |
Oral ftorafur versus intravenous 5-fluorouracil. A comparative study in patients with colorectal cancer.
Topics: Administration, Oral; Adult; Aged; Blood Platelets; Colonic Neoplasms; Female; Fluorouracil; Humans; | 1987 |
[Clinical effect of postoperative adjuvant immunochemotherapy with the FT-207 suppository and PSK in colorectal cancer patients. Colorectal Cancer Chemotherapy Group in Hokuriku].
Topics: Administration, Oral; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Hu | 1988 |
[A cooperative study of surgical adjuvant chemotherapy of colorectal cancer (second report): 3-year survival rate. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Humans; Mitomycin; M | 1988 |
[Results of phase III study of lentinan].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neopl | 1985 |
[Studies on the effects of adjuvant chemotherapy on the survival period of patients with colorectal carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Th | 1985 |
209 other studies available for tegafur and Cancer of Rectum
| Article | Year |
|---|---|
The effect of Mitomycin-C in neoadjuvant concurrent chemoradiotherapy for rectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Disease-Free Survival; Humans; Mi | 2022 |
Clinical T2N0 Rectal Cancer Treated with Neoadjuvant Chemoradiotherapy plus Local Excision.
Topics: Chemoradiotherapy; Humans; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Qualit | 2023 |
Reply to "The impact of adding mitomycin-C to radiotherapy plus oral tegafur-uracil (CCRT) on advanced-stage rectal cancer?"
Topics: Antineoplastic Combined Chemotherapy Protocols; Humans; Mitomycin; Rectal Neoplasms; Tegafur | 2023 |
Reply to "The impact of adding mitomycin-C to radiotherapy plus oral tegafur-uracil (CCRT) on advanced-stage rectal cancer?"
Topics: Antineoplastic Combined Chemotherapy Protocols; Humans; Mitomycin; Rectal Neoplasms; Tegafur | 2023 |
Reply to "The impact of adding mitomycin-C to radiotherapy plus oral tegafur-uracil (CCRT) on advanced-stage rectal cancer?"
Topics: Antineoplastic Combined Chemotherapy Protocols; Humans; Mitomycin; Rectal Neoplasms; Tegafur | 2023 |
Reply to "The impact of adding mitomycin-C to radiotherapy plus oral tegafur-uracil (CCRT) on advanced-stage rectal cancer?"
Topics: Antineoplastic Combined Chemotherapy Protocols; Humans; Mitomycin; Rectal Neoplasms; Tegafur | 2023 |
The impact of adding mitomycin-C to radiotherapy plus oral tegafur-uracil on advanced-stage rectal cancer.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol | 2023 |
N2 Lymph Node Metastasis Is a Useful Predictor of Recurrence in Patients With Stage III Rectal Cancer Undergoing Adjuvant Chemotherapy Using Tegafur-uracil/leucovorin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Humans | 2023 |
Monthly tegafur-uracil maintenance for increasing relapse-free survival in ypStage III rectal cancer patients after preoperative radiotherapy, radical resection, and 12 postoperative chemotherapy cycles: a retrospective study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; | 2019 |
[One case of advanced rectal cancer after nephrectomy treated with low doses of Apatinib and Tegafur].
Topics: Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; Humans; Nephrectomy; Pyridines; R | 2019 |
[A Case of Curatively Resected Locally Recurrent Rectal Mucinous Adenocarcinoma Followed by Preoperative Chemoradiotherapy].
Topics: Adenocarcinoma, Mucinous; Antimetabolites, Antineoplastic; Chemoradiotherapy; Drug Combinations; Hum | 2019 |
Transcatheter rectal arterial chemoembolization with oxaliplatin plus S-1 concurrent chemoradiotherapy can improve the pathological remission rate in locally advanced rectal cancer: a comparative study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Colore | 2020 |
[Long-Term Clinical Complete Response after Preoperative Chemoradiotherapy in a Patient with Locally Advanced, Lower Rectal Cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Female; Humans; Irinotecan; | 2020 |
Abnormal Neuronal Response to Rectal and Anal Stimuli in Patients Treated for Distal Rectal Cancer With High-Dose Chemoradiotherapy Followed By Watchful Waiting.
Topics: Adenocarcinoma; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studi | 2020 |
Reversible Splenial Lesion Syndrome (RESLES) After Chemotherapy of Oral Tegafur-uracil in a Female With Locally Rectal Adenocarcinoma.
Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Brain Diseases; Female; Humans; Rectal Neopl | 2020 |
Efficacy and tolerability of preoperative chemoradiotherapy with S-1 alone for locally advanced rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Chemoradiotherapy; Disease-Free Survival; Drug Combinations; Female; | 2021 |
Tolerability and safety of adjuvant chemoradiotherapy with S-1 after limited surgery for T1 or T2 lower rectal cancer.
Topics: Chemoradiotherapy, Adjuvant; Humans; Neoplasm Recurrence, Local; Oxonic Acid; Prospective Studies; P | 2021 |
Gene expression levels of gamma-glutamyl hydrolase in tumor tissues may be a useful biomarker for the proper use of S-1 and tegafur-uracil/leucovorin in preoperative chemoradiotherapy for patients with rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Combined Che | 2017 |
[A Case of Effective Chemoradiotherapy Using mFOLFOX6 for Locally Advanced Rectal Cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy; Drug Combinations; | 2017 |
[A Curatively Resected Case of Lateral Lymph Node Metastasis Five-Years after Initial Surgery for Rectal Cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Humans; Leucovorin; Lymph Node Excision; Lymph | 2017 |
Identification of Predictors of Recurrence in Patients with Lower Rectal Cancer Undergoing Neoadjuvant Chemotherapy: A Direct Comparison of Short-Course and Long-Course Chemoradiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; C | 2019 |
Carcinoembryonic antigen (CEA) level, CEA ratio, and treatment outcome of rectal cancer patients receiving pre-operative chemoradiation and surgery.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biom | 2013 |
C-reactive protein as predictor of recurrence in patients with rectal cancer undergoing chemoradiotherapy followed by surgery.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Proto | 2013 |
Metachronous, colitis-associated rectal cancer that developed after sporadic adenocarcinoma in an adenoma in a patient with longstanding Crohn's disease: a case report.
Topics: Adenocarcinoma, Mucinous; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring Cel | 2013 |
[An appropriate distal resection margin for lower rectal cancer after preoperative chemoradiotherapy].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemor | 2013 |
[Ten cases of locally advanced rectal cancer that were treated with preoperative chemotherapy with S-1 plus oxaliplatin].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Humans; Male | 2013 |
Preoperative chemoradiotherapy with oxaliplatin and tegafur-uracil in locally advanced rectal cancer: pathologic complete response rate and preliminary results of overall and disease-free survival in a single institute in Taiwan.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P | 2014 |
Assessment of the value of carcinoembryonic antigen reduction ratio as a prognosis factor in rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carc | 2014 |
CD8+ and FOXP3+ tumor-infiltrating T cells before and after chemoradiotherapy for rectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; CD8-Positive T-Lymphocytes; Chemoradiotherapy; | 2014 |
[Induction chemotherapy with S-1/oxaliplatin prevented colostomy in a patient with advanced rectal cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colostomy; Drug Combin | 2014 |
[A case of advanced rectal cancer that showed complete response to the addition of XELOX+bevacizumab therapy to preoperative chemoradiotherapy with S-1/CPT-11].
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camp | 2014 |
Post-chemoradiation intraoperative electron-beam radiation therapy boost in resected locally advanced rectal cancer: long-term results focused on topographic pattern of locoregional relapse.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; E | 2014 |
[A case of a patient with advanced rectal cancer and urinary bladder fistula surviving for 6 years after chemoradiotherapy without surgery].
Topics: Antimetabolites, Antineoplastic; Chemoradiotherapy; Drug Combinations; Humans; Male; Middle Aged; Ox | 2014 |
The timing of surgery after preoperative short-course S-1 chemoradiotherapy with delayed surgery for T3 lower rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemoradiotherapy; | 2014 |
S-1-Based versus capecitabine-based preoperative chemoradiotherapy in the treatment of locally advanced rectal cancer: a matched-pair analysis.
Topics: Capecitabine; Chemoradiotherapy; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Humans; Mal | 2014 |
Adaptation of international guidelines for metastatic colorectal cancer: an asian consensus.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot | 2014 |
Chemoradiation provides a physiological selective pressure that increases the expansion of aberrant TP53 tumor variants in residual rectal cancerous regions.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; DNA, Neoplasm; Humans; | 2014 |
[A case of pathological complete response to lt. Lateral lymph node metastasis from lower rectal cancer by S-1 combined neoadjuvant chemoradiotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Drug Combinations | 2014 |
[Complete response in a case of anastomotic recurrence of rectal cancer treated with S-1 monotherapy].
Topics: Antimetabolites, Antineoplastic; Drug Combinations; Female; Humans; Middle Aged; Neoplasm Recurrence | 2014 |
Feasibility of modified short-course radiotherapy combined with a chemoradiosensitizer for T3 rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Chemora | 2015 |
Is it time for watchful waiting for rectal cancer?
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Brachytherapy; Chemoradiotherapy; Female; Humans; M | 2015 |
High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Biopsy; Brachytherapy; | 2015 |
High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Biopsy; Brachytherapy; | 2015 |
High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Biopsy; Brachytherapy; | 2015 |
High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Biopsy; Brachytherapy; | 2015 |
High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Biopsy; Brachytherapy; | 2015 |
High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Biopsy; Brachytherapy; | 2015 |
High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Biopsy; Brachytherapy; | 2015 |
High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Biopsy; Brachytherapy; | 2015 |
High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Biopsy; Brachytherapy; | 2015 |
Number of Lymph Nodes in Rectal Cancer is Correlated with Response to Preoperative Chemoradiotherapy but is not Associated with Patient Survival.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Disease Progression; D | 2014 |
Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer.
Topics: Chemoradiotherapy; Female; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Neoplasm | 2015 |
Prognostic significance of pathological response to preoperative chemoradiotherapy in patients with locally advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adju | 2016 |
Clinicopathological outcomes of preoperative chemoradiotherapy using S-1 plus Irinotecan for T4 lower rectal cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiothe | 2016 |
The short-term outcomes of induction SOX (S-1 + oxaliplatin) ± cetuximab chemotherapy followed by short-course chemoradiotherapy in patients with poor-risk locally advanced rectal cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Chemoradiotherap | 2016 |
CT images of enterohaemorrhagic Escherichia coli colitis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colitis; Drug Combinations; Esche | 2016 |
[A Case of a Submucosal Tumor-Like Gastric Cancer That Needed to Be Distinguished from Gastric Metastasis of Rectal Cancer].
Topics: Antimetabolites, Antineoplastic; Drug Combinations; Gastric Mucosa; Humans; Male; Middle Aged; Neopl | 2015 |
[A Case of Locally Advanced Rectal Cancer with a Pathological Complete Response to Preoperative Chemoradiotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Female; Humans; L | 2015 |
[Adjuvant Systemic Chemotherapy with S-1/Oxaliplatin or mFOLFOX6 after Curative Resection of Distant Metastases in Patients with Colorectal Cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Dru | 2016 |
[A Case Report of a Pathological Complete Response of Rectal Cancer to Preoperative Chemoradiotherapy with Tegafur].
Topics: Aged; Antimetabolites, Antineoplastic; Biopsy; Chemoradiotherapy; Drug Combinations; Humans; Male; N | 2016 |
Increase in Gene Expression of TYMP, DPYD and HIF1A Are Associated with Response to Preoperative Chemoradiotherapy Including S-1 or UFT for Rectal Cancer.
Topics: Adult; Aged; Chemoradiotherapy; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Gene | 2016 |
[Comparison of the Cost-Effectiveness of the SOX and COX Regimens in Patients with Unresectable Advanced and Recurrent Colorectal Cancer Using a Clinical Decision Analysis Approach].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colonic Neoplasms; Cost-Benefit | 2016 |
A Comparative Effectiveness Study of Two Oral Chemotherapy Drugs (UFT vs. Capecitabine) in Neoadjuvant Concurrent Chemoradiotherapy for Patients with Locally Advanced Rectal Cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Female; | 2016 |
[A Case of Pathological Complete Response after Neoadjuvant Chemotherapy(S-1 plus Oxaliplatin)and Laparoscopic Low Anterior Resection for Rectal Cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Humans; Intestinal Obstruction; L | 2016 |
[Effectiveness of Irinotecan, S-1, and Bevacizumab for Rectal Cancer with Lung and Skin Metastases after Adjuvant Chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; D | 2016 |
[A Case of Laparoscopic Surgery for Rectal Cancer with Synchronous Lung Metastases after Chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colostomy; Drug Combinations; Fem | 2016 |
[A Case of Rectal Metastasis of Gastric Cancer Associated with Dermatomyositis].
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Dermatomyositis; Drug Combinations; Fatal Out | 2016 |
Prediction of Pathological Complete Response Using Endoscopic Findings and Outcomes of Patients Who Underwent Watchful Waiting After Chemoradiotherapy for Rectal Cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carc | 2017 |
[A case of metastatic lung and liver tumors from rectal cancer treated with oral UFT and CPT-11 by hepatic arterial infusion followed by FOLFOX and FOLFIRI].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptotheci | 2008 |
Relationships of insulin-like growth factor-1 receptor and epidermal growth factor receptor expression to clinical outcomes in patients with colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Colorectal Neoplasm | 2009 |
[Our experiences of preoperative chemo-radiotherapy for T4 primary rectal cancer].
Topics: Antineoplastic Agents; Drug Combinations; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Thera | 2008 |
[Complete response of advanced rectal cancer with combined therapy of S-1 + chemo-radiation plus FOLFIRI--a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Drug Combinations; | 2008 |
Laparoscopic resection of extraperitoneal rectal cancer: a comparative analysis with open resection.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Mod | 2009 |
[A case of simultaneous double cancers with multiple liver metastases responding to S-1+CPT-11].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Carcinoembryonic Antigen | 2009 |
Postoperative chemotherapy after neoadjuvant chemoradiation and surgery for rectal cancer: is it essential for patients with ypT0-2N0?
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuv | 2009 |
Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy.
Topics: AC133 Antigen; Adult; Aged; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Biomarkers | 2009 |
[A case of disease-free survival with low-dose chemotherapy after resection of hepatic and pulmonary metastases from rectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Hepatectomy; Humans; Liver Ne | 2009 |
[A case of advanced colon cancer treated with preoperative chemotherapy (IRIS) leading to clinical complete response].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Chemotherapy | 2009 |
[A case of recurrent rectal cancer with multiple lung metastases successfully treated with S-1 and CPT-11 combination chemotherapy].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Combinatio | 2009 |
[A case of advanced rectal cancer that responded to S-1 with an extended complete response].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Combina | 2009 |
[Effect on neoadjuvant chemotherapy using s-1 for unresectable liver metastasis from rectal cancer-a case report].
Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Drug Combinations; Female; Hepatectomy; Huma | 2009 |
[Preoperative chemoradiotherapy for resectable lower rectal cancer].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combin | 2009 |
[Assessment of chemoradiation therapy for advanced rectal cancer invaded the pelvic organ].
Topics: Adenocarcinoma, Mucinous; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modalit | 2009 |
[A resected case of pathologically complete response of a pelvic recurrence from rectal cancer after chemoradiotherapy with S-1].
Topics: Antimetabolites, Antineoplastic; Drug Combinations; Humans; Male; Middle Aged; Neoadjuvant Therapy; | 2009 |
[A case of locally recurrent rectal cancer responding to radiation and chemotherapy with S-1].
Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Drug Combinations; Humans; Male; Middle | 2009 |
[A case of complete response to S-1 therapy for multiple pulmonary recurrences of hepatocellular carcinoma after hepatic resection].
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Drug Combinations; Hepatectomy; Hu | 2009 |
Gas in portal circulation and pneumatosis cystoides intestinalis during chemotherapy for advanced rectal cancer.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined C | 2010 |
[A case of complete response after treatment with UFT and leucovorin for synchronous multiple liver metastases of rectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leucovorin; Liver Neoplasms; Magneti | 2010 |
Focal dose escalation using FDG-PET-guided intensity-modulated radiation therapy boost for postoperative local recurrent rectal cancer: a planning study with comparison of DVH and NTCP.
Topics: Antimetabolites, Antineoplastic; Dose-Response Relationship, Radiation; Drug Combinations; Fluorodeo | 2010 |
[A case of metachronous multiple lung metastases and intraabdominal lymph node metastases of rectal cancer responding to S-1].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Humans; Lung Neoplasms; Lym | 2010 |
Circulating lymphocyte number has a positive association with tumor response in neoadjuvant chemoradiotherapy for advanced rectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Ther | 2010 |
A case of pathological complete response of advanced rectal cancer to preoperative chemoradiotherapy using S-1.
Topics: Adult; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colostomy; Drug Combinations; Female | 2010 |
[A case of rectal cancer combined with intraperitoneal abscess responding completely to uracil/tegafur (UFT) plus oral leucovorin (LV) therapy].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colostomy; Combined Modality T | 2010 |
[A case of advanced rectal cancer with multiple liver metastases successfully treated by perioperative administration of UFT and oral leucovorin].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therap | 2010 |
The impact of preoperative chemoradiotherapy on advanced low rectal cancer.
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Combined Modal | 2010 |
[A case with local recurrence of rectal cancer that responded to S-1 and PSK with long-term complete response].
Topics: Adenocarcinoma, Mucinous; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antine | 2010 |
Standard-dose tegafur combined with uracil is not safe treatment after severe toxicity from 5-fluorouracil or capecitabine.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Dihydropyrimidine Dehydrogenase Defici | 2010 |
[Long-term control of sacral metastasis from rectal cancer with S-1 + radiation treatment (RT) and mFOLFOX6 combination therapy--a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Dru | 2010 |
[A long-term survival case of rectal cancer with Virchow's lymph node metastasis by multimodality therapy].
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A | 2010 |
[A long-term disease-free survival case of advanced rectal cancer with massive metastasis to the lateral pelvic and para-aortic lymph nodes].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined C | 2010 |
[An experience of curative resection of local recurrent rectal cancer with high-level sacrectomy after preoperative chemo-radiation therapy].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Com | 2010 |
[A case report of locally advanced rectal carcinoma effectively treated with preoperative chemoradiotherapy].
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Drug Combinations; Fe | 2010 |
[A case of local relapsed rectal cancer responding to low-dose S-1].
Topics: Administration, Oral; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Ch | 2010 |
[A case of synchronous hepatic and multiple pulmonary metastases from rectal cancer responding completely to UFT therapy after resection of primary and hepatic lesions].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Humans; Liver Neo | 2011 |
[A case of rectal cancer with sacrum metastasis treated with S-1 leading to a complete response].
Topics: Antimetabolites, Antineoplastic; Bone Neoplasms; Drug Combinations; Female; Humans; Magnetic Resonan | 2011 |
[Effecacy of three-dimensional conformal radiation therapy combined with Tegafur for postoperative recurrent rectal carcinoma].
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Diarrhea; E | 2011 |
[A case of drug-induced interstitial pneumonitis after chemotherapy with UFT and leucovorin for multiple lung metastases of rectal cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Humans; Leucovorin; Lung Diseases, Interstitia | 2011 |
[Response in a case of advanced rectal cancer treated by chemoradiation with S-1/oxaliplatin].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Combined Modality Therapy; Drug Combinations | 2011 |
Pretreatment CD133 and cyclooxygenase-2 expression as the predictive markers of the pathological effect of chemoradiotherapy in rectal cancer patients.
Topics: AC133 Antigen; Adult; Aged; Aged, 80 and over; Antigens, CD; Antimetabolites, Antineoplastic; Biomar | 2011 |
[A case of carcinoma associated with anal fistula resected after preoperative chemoradiotherapy].
Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Drug Combinations; Humans; Magnetic Reso | 2011 |
[A case of synchronous multiple liver metastases of rectal cancer successfully treated with tegafur/uracil and oral leucovorin chemotherapy].
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combi | 2011 |
Prognostic significance of glucose transporter-1 (GLUT1) gene expression in rectal cancer after preoperative chemoradiotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Line, Tumor; Ch | 2012 |
[Synchronous double cancer of the gallbladder and rectum successfully treated with S-1 as second-line chemotherapy- a case report].
Topics: Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Drug Combinations; Fatal Outcome; | 2011 |
Safety and outcome of chemoradiotherapy in elderly patients with rectal cancer: results from two French tertiary centres.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycyti | 2012 |
[Preoperative chemoradiotherapy with S-1 for advanced low rectal cancer].
Topics: Aged; Antimetabolites, Antineoplastic; Chemoradiotherapy; Drug Combinations; Female; Humans; Male; M | 2011 |
[A case report of pathologically complete response of rectal cancer after preoperative treatment of CPT-11, S-1, and radiation therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy; Drug Combinations; | 2011 |
[A case of long-term survival after curative resection of advanced rectal cancer treated by pre-operative chemoradiotherapy].
Topics: Antimetabolites, Antineoplastic; Chemoradiotherapy; Drug Combinations; Female; Humans; Liver Neoplas | 2011 |
[A case of remnant liver metastases after resection of liver metastases from rectal cancer following treatment with 5-FU, L-OHP and CPT-11, with markedly effective treatment by cetuximab plus S-1].
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap | 2012 |
[Complete disappearance of pulmonary metastases in a case of rectal cancer treated with oral tegafur-uracil (UFT) and leucovorin (LV)].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Humans; Leucovorin; Lung Neopl | 2012 |
Early prediction of histopathological response of rectal tumors after one week of preoperative radiochemotherapy using 18 F-FDG PET-CT imaging. A prospective clinical study.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiothe | 2012 |
Biopsy specimens obtained 7 days after starting chemoradiotherapy (CRT) provide reliable predictors of response to CRT for rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Apoptosis; Biomarke | 2013 |
[Neoadjuvant chemoradiotherapy for locally advanced rectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy; Drug Combinations; | 2012 |
[A patient with multiple liver metastases of gastric and rectal cancers after laparoscopic sigmoidectomy who responded completely to S-1 therapy followed by open gastrectomy].
Topics: Aged; Antimetabolites, Antineoplastic; Colectomy; Combined Modality Therapy; Drug Combinations; Gast | 2012 |
[CPT-11 hepatic arterial injection plus oral UFT administration for liver metastasis of rectal cancer--report of two cases].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptoth | 2002 |
[A case of unresectable rectal cancer with liver and pulmonary metastases that responded remarkably to pharmacokinetic modulating chemotherapy].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Drug Administr | 2002 |
[A case of colon metastasis to the lung treated successfully with combined chemotherapy of CPT-11 and 5'-DFUR].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Sc | 2002 |
Oral uracil/ftorafur (UFT) plus leucovorin as first-line chemotherapy and salvage therapy with weekly high-dose 5-fluorouracil/leucovorin for the treatment of metastatic colorectal cancer.
Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; D | 2002 |
[A case of liver and lung metastases of rectal cancer responding well to 5-FU hepato-arterial infusion (HAI) with combined use of oral UFT].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Sche | 2003 |
[A case of hepatic metastasis and local recurrence from rectal cancer responding to hepatic arterial infusion and systemic chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administrat | 2003 |
18F-FDG positron emission tomography staging and restaging in rectal cancer treated with preoperative chemoradiation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorodeoxyglucos | 2004 |
Oral tegafur/folinic acid chemotherapy decreases phenytoin efficacy.
Topics: Administration, Oral; Anticonvulsants; Antimetabolites, Antineoplastic; Carcinoma; Drug Interactions | 2004 |
[A case of multiple pulmonary metastases from rectal cancer effectively treated by TS-1 and low-dose CDDP therapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cisplatin; Combin | 2004 |
[Case report--Complete response of liver metastasis of rectal cancer after combination chemotherapy of CPT-11 + UFT-E].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Humans; | 2004 |
Immunohistochemical evaluation of thymidylate synthase (TS) and p16INK4a in advanced colorectal cancer: implication of TS expression in 5-FU-based adjuvant chemotherapy.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Chemotherapy, Adjuvant; Colonic Neoplasms; C | 2004 |
Pre-operative chemoradiotherapy with oral tegafur-uracil and leucovorin for rectal cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemot | 2005 |
[Pharmacokinetic modulating chemotherapy for rectal carcinoma metastases to the liver and lung--a case report].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dru | 2005 |
Preoperative chemoradiation with oral tegafur within a multidisciplinary therapeutic approach in patients with T3-4 rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Humans; Male; Middle Aged; Neoadjuvan | 2005 |
Leflunomide and peripheral neuropathy: a potential interaction between uracil/tegafur and leflunomide.
Topics: Administration, Oral; Aged; Arthritis, Rheumatoid; Comorbidity; Disease Progression; Drug Administra | 2005 |
The benefit of post-operative adjuvant chemotherapy using oral fluoropyrimidines in rectal cancer.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Female; | 2005 |
Neoadjuvant therapy of rectal cancer using oral tegaful-uracil (UFT) plus concomitant radiotherapy--a case report.
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Humans; Male; | 2005 |
Preoperative chemoradiation of locally advanced T3 rectal cancer combined with an endorectal boost.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bra | 2006 |
[Efficacy of tegafur/uracil plus oral leucovorin therapy for advanced or recurrent colorectal cancer].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms | 2005 |
[A case of rectal cancer treated by preoperative chemoradiation].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colostomy; | 2005 |
[Rectal stenosis due to Schnitzler metastasis following surgery for gastric cancer--a case successfully treated with TS-1 and CDDP combination chemotherapy].
Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combin | 2005 |
[A case of an increase in resectability with preoperative chemotherapy TS-1 combined with CPT-11 for unresectable rectal cancer in downstaging].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Sc | 2005 |
Prognostic factors for disease-free survival in patients with T3-4 or N+ rectal cancer treated with preoperative chemoradiation therapy, surgery, and intraoperative irradiation.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Comb | 2006 |
Improved incidence of pT0 downstaged surgical specimens in locally advanced rectal cancer (LARC) treated with induction oxaliplatin plus 5-fluorouracil and preoperative chemoradiation.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th | 2006 |
[New treatment strategies for patients with primary non-resectable rectal cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera | 2006 |
[Second-line chemotherapy with pharmacokinetic modulating chemotherapy for unresectable colorectal carcinoma recurrences resistant to 5-FU-based chemotherapy].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chronotherapy; Co | 2006 |
[Advanced rectal cancer in an older patient, in whom metastatic liver lesions were effectively controlled with oral UFT+LV and venous CPT-11 administration--case report].
Topics: Adenocarcinoma; Administration, Oral; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protoc | 2006 |
Quality of Life assessment through the EORTC questionnaires of locally advanced rectal cancer patients treated with preoperative chemo-radiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Body Image; Emotions | 2006 |
[Retrospective analysis of tegafur/uracil (UFT) plus oral leucovorin (LV) regimen in patients with advanced colorectal cancer].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2006 |
Tegafur and 5-fluorouracil pelvic tissue concentrations in rectal cancer patients receiving preoperative chemoradiation.
Topics: Adipose Tissue; Adult; Aged; Antimetabolites, Antineoplastic; Female; Fluorouracil; Humans; Intestin | 2006 |
[A case of rectal cancer with multiple liver metastases responding to TS-1].
Topics: Adenocarcinoma; Ambulatory Care; Antimetabolites, Antineoplastic; Biomarkers, Tumor; CA-19-9 Antigen | 2006 |
[A case of effective multidisciplinary treatment with hepatic resection for synchronous multiple liver metastases from rectal cancer].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubic | 2006 |
[A case of advanced rectal cancer responding to oral UFT and Leucovorin-based preoperative chemoradiation therapy].
Topics: Adenocarcinoma; Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Combine | 2006 |
[CR of rectal cancer and synchronous liver and lung metastases obtained with TS-1 plus CPT-11 combination therapy--case report].
Topics: Adenomatous Polyposis Coli; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Com | 2007 |
[A case of effective regimen of tegafur and uracil (UFT)/leucovorin (LV) plus irinotecan (CPT-11) for advanced rectal carcinoma with severe pelvic infiltration to be performed curative resection].
Topics: Adenocarcinoma; Administration, Oral; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Pr | 2007 |
[An inadvertent contraindicated combined use of newly prescribed TS-1 and unused doxifluridine].
Topics: Aged; Contraindications; Drug Combinations; Floxuridine; Humans; Male; Medication Errors; Oxonic Aci | 2007 |
Predictors of tumor downsizing and regression with preoperative radiotherapy alone and with concomitant tegafur/uracil (UFT) for resectable advanced rectal adenocarcinoma.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; | 2007 |
UFT/leucovorin and mitomycin C as salvage treatment in patients with advanced colorectal cancer - a retrospective analysis.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colonic Neo | 2007 |
[A case of metastatic rectal cancer showing a sustained complete response to chemotherapy with FOLFIRI followed by UFT].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Humans; L | 2007 |
[Neoadjuvant chemotherapy with combination of S-1 and CPT-11 in advanced rectal cancer - a case report].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemothe | 2007 |
[An elderly patient with recurrent rectal cancer successfully responded to S-1 combined with CPT-11].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonoscopy; Drug C | 2007 |
[A case of dihydropyrimidine dehydrogenase (DPD) deficiency with severe side effects from UFT/Uzel administration].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Dihydropyrimidine Dehy | 2008 |
[A case of advanced rectal cancer responding to radiation therapy and chemotherapy with S-1].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonoscopy; Combined Modality Therapy; Drug C | 2008 |
[A case of lumbar metastases from rectal cancer successfully treated by UFT plus oral leucovorin (LV) therapy].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neopla | 2008 |
[Effects of 5'-deoxy-5-fluorouridine on human gastrointestinal and breast cancers xenografted to nude mice].
Topics: Adenocarcinoma; Administration, Oral; Animals; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Femal | 1984 |
Continuous intravenous administration of 1-(2-tetrahydrofuryl)-5-fluorouracil [FT] by intravenous hyperalimentation (IVH)--stability of FT in IVH solution and tumor levels of 5-fluorouracil (5-FU).
Topics: Colonic Neoplasms; Dose-Response Relationship, Drug; Fluorouracil; Humans; Parenteral Nutrition, Tot | 1983 |
Phase II study of ftorafur in previously untreated and treated patients with advanced colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male; | 1983 |
[Chemotherapy of gastric and rectal cancers incorporating non-radical irradiation during remission induction. 1].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromomycin A3; Combined Modality Therapy; Cyclophos | 1984 |
[Cooperative phase II study of spansule tegafur (SF-SP)].
Topics: Administration, Oral; Aged; Breast Neoplasms; Capsules; Colonic Neoplasms; Delayed-Action Preparatio | 1984 |
Phase I-II studies of oral tegafur (ftorafur).
Topics: Administration, Oral; Bone Marrow; Breast Neoplasms; Colonic Neoplasms; Dose-Response Relationship, | 1983 |
[The case studies on oral administration of tegafur encapsulated with slow releasing granule (SF-SP) for three rectal patients].
Topics: Adenocarcinoma; Administration, Oral; Aged; Capsules; Delayed-Action Preparations; Female; Fluoroura | 1984 |
[Experimental chemotherapy of human gastrointestinal and breast cancers in nude mice and its correlation to clinical effect].
Topics: Adenocarcinoma; Adult; Aged; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Pr | 1984 |
[Study on the concentration of FT-207 and 5-FU in serum, lymph nodes and tissues after administration of FT-207 suppositories].
Topics: Adult; Aged; Breast Neoplasms; Female; Fluorouracil; Humans; Lymph Nodes; Lymphoma, Non-Hodgkin; Mal | 1984 |
Comparative efficacy of antitumor treatment for liver metastases from colorectal cancer.
Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Hepatic Artery; Humans; | 1981 |
[Clinical trial of UFT in recurrent or advanced cancer].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasm | 1982 |
[Clinical study of serum and tissue concentrations of FT-207 and 5-FU in patients with cancer of the large intestine following preoperative application of FT-207 suppositories].
Topics: Adult; Aged; Biological Assay; Female; Fluorouracil; Humans; Intestinal Neoplasms; Intestine, Large; | 1982 |
Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group.
Topics: Administration, Oral; Aged; Aged, 80 and over; Ambulatory Care; Antidotes; Antimetabolites, Antineop | 1997 |
Life-threatening toxicity of oral tegafur-uracil (UFT) plus leucovorin.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 1997 |
[Preoperative chemotherapy for advanced colorectal carcinomas--comparison of histological effect between UFT + leucovorin tablet and UFT alone].
Topics: Administration, Oral; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Colonic Neopl | 1998 |
[Complete remission of liver metastasis from rectal cancer following continuous oral administration of tegafur-uracil after intrahepatic arterial single injection of CDDP and 5-FU].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinat | 1998 |
[A case of rectal cancer with lymph node metastasis (N4) successfully treated with low-dose cisplatin and UFT].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplati | 1999 |
[Long-term complete response in a case of unresectable rectal cancer following chemoradiation].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy | 2000 |
[A case of advanced rectal cancer with unresectable liver metastasis for which chemotherapy was markedly effective].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Combined Modal | 2000 |
Phase II study of oral tegafur-uracil and folinic acid as first-line therapy for metastatic colorectal cancer: Taiwan experience.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; C | 2000 |
[Long survival in a case of unresectable hepatic metastasis from rectal carcinoma treated with second-look hepatectomy plus pharmacokinetic modulating chemotherapy (PMC)].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dru | 2001 |
Animal model of para-aortic lymph node metastasis.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Aorta; Carcinoma, Squamous | 2001 |
[A case report of rectal cancer with liver and pulmonary metastases responding to TS-1].
Topics: Adenocarcinoma; Administration, Oral; Antimetabolites, Antineoplastic; Drug Administration Schedule; | 2001 |
Pathologic downstaging of T3-4Nx rectal cancer after chemoradiation: 5-fluorouracil vs. Tegafur.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; | 2001 |
[A case of liver metastasis of rectal cancer demonstrating complete response to 5-FU + Leucovorin + UFT].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug C | 2002 |
[A case of rectal cancer with multiple liver metastases that responded dramatically to pharmacokinetic modulating chemotherapy/CPT-11 therapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Hepatic Artery; | 2002 |
[Therapeutic effect of ftorafur].
Topics: Adenocarcinoma; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Female; Fluorouracil; Mammary Gland | 1977 |
Chemoimmunotherapy of metastatic large bowel cancer: nonspecific stimulation with BCG and levamisole.
Topics: BCG Vaccine; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Levamisole; Lomusti | 1977 |
Phase II clinical trial of ftorafur in 5-fluorouracil-refractory colorectal cancer.
Topics: Adult; Aged; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Re | 1977 |
Chemoimmunotherapy with BCG and FT 207 (II).
Topics: BCG Vaccine; Colonic Neoplasms; Fluorouracil; Humans; Rectal Neoplasms; Tegafur | 1978 |
Phase II evaluation of ftorafur in previously untreated colorectal cancer: a Southwest Oncology Group Study.
Topics: Adenocarcinoma; Adult; Aged; Central Nervous System; Colonic Neoplasms; Drug Evaluation; Female; Flu | 1979 |
Phase I-II study of ftorafur and methyl-CCNU in advanced colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Bone Marrow; Colonic Neoplasms; Digestive System; Drug Evaluation; Drug | 1979 |
Leukoencephalopathy induced by tegafur: serial studies of somatosensory evoked potentials and cerebrospinal fluid.
Topics: Akinetic Mutism; Evoked Potentials, Somatosensory; Humans; Leukoencephalopathy, Progressive Multifoc | 1992 |
[Neo-adjuvant chemotherapy with tegafur suppository for rectal cancer--evaluation of the antitumor effects, tissue levels of 5-FU and inhibition of thymidylate synthase. Tochigi Colorectal Cancer Study Group].
Topics: Chemotherapy, Adjuvant; Female; Fluorouracil; Humans; Male; Rectal Neoplasms; Suppositories; Tegafur | 1992 |
Extensive en bloc resection of regionally recurrent carcinoma of the rectum.
Topics: Adenocarcinoma; Adult; Aged; Chemotherapy, Adjuvant; Female; Humans; Male; Middle Aged; Neoplasm Rec | 1992 |
[Histopathological findings in rectal carcinomas undergoing preoperative irradiation combined with chemotherapy].
Topics: Adenocarcinoma; Adult; Aged; Combined Modality Therapy; Female; Humans; Lymphatic Metastasis; Male; | 1992 |
[Complete response in a case of rectal carcinoma with multiple liver metastasis treated by infuse-a-port].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Hepatic Artery; Humans | 1991 |
[A case of local recurrence of rectal cancer successfully treated by UFT combined with two-route CDDP chemotherapy under the AT-II induced hypertension].
Topics: Adenocarcinoma; Administration, Oral; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols | 1991 |
[Clinicopathological study on rectal cancer after sphincter-saving operation in conjunction with preoperative radiation therapy].
Topics: Combined Modality Therapy; Female; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurre | 1991 |
[Treatment with UFT as surgical adjuvant chemotherapy in carcinoma of large intestine. Cooperative Study Group of Surgical Adjuvant Chemotherapy for Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Hum | 1990 |
[Myelodysplastic syndrome (RAEB-T) occurring after adjuvant chemotherapy for colon and rectum cancers].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Colonic Neoplasms; Cytarabine; DN | 1990 |
[Five cases of rectal cancer showing remarkable response to suppository administration of tegafur].
Topics: Adult; Aged; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Rectal Neoplasms; Supposi | 1989 |
[Effects of preoperative administration of UFT in gastrointestinal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Humans; Kine | 1986 |
[Anosmia or hyposmia after long-term oral administration of tegafur--improved anosmia].
Topics: Aged; Breast Neoplasms; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Olfaction D | 1986 |
[5-FU concentration in the blood and tissue of patients with gastric and colorectal cancer after administration of UFT or tegafur].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Male; Rats | 1986 |
[Comparative clinical studies of colorectal tumor tissue and normal tissue following arterial injection of tegafur].
Topics: Adult; Aged; Colonic Neoplasms; Female; Humans; Injections, Intra-Arterial; Male; Middle Aged; Recta | 1987 |
[Serum concentration of 5-FU and tegafur (FT-207) after administration of tegafur (FT-207) suppository with the colostomy].
Topics: Adult; Aged; Colostomy; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged; | 1987 |
[Human colorectal carcinoma is more sensitive to HCFU than 5-FU and tegafur in in vitro and in vivo drug sensitivity tests].
Topics: Animals; Colonic Neoplasms; Fluorouracil; Humans; Mice; Rectal Neoplasms; Subrenal Capsule Assay; Te | 1988 |
[Antitumor effect of intermittent oral administration of UFT against human rectal cancer xenografted in nude mice].
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Drug Adm | 1988 |
[A case of colorectal cancer showing complete response to UFT].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined M | 1988 |
[The serum and tissue concentrations of tegafur, 5-fluorouracil and uracil in patients with gastric and colorectal cancers after oral administration of UFT].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouraci | 1988 |
[A case of rectal carcinoma that disappeared following preoperative chemotherapy with an FT-207 suppository--confirmed by a thorough histologic examination of the resected specimen].
Topics: Adenocarcinoma; Administration, Rectal; Female; Humans; Middle Aged; Preoperative Care; Rectal Neopl | 1988 |
Long-term survivors of colorectal cancer with unresectable hepatic metastases.
Topics: Administration, Oral; Aged; Carcinoembryonic Antigen; Colonic Neoplasms; Female; Fluorouracil; Human | 1985 |