tegafur has been researched along with Cancer of Head in 131 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, its efficacy in treating advanced head and neck neoplasms has not been reported." | 5.51 | Apatinib and S-1 combination therapy for the treatment of advanced head and neck neoplasms: Three case reports. ( Han, X; Huang, G; Li, W; Meng, M; Ni, Y; Wang, J; Wei, Z; Yang, X; Ye, X, 2019) |
| "Patients with stage III, IVA, or IVB LAHNSCC were enrolled in this study to evaluate the efficacy of S-1 compared with UFT as adjuvant chemotherapy after curative CRT in the ACTS-HNC study." | 2.87 | Adjuvant chemotherapy with S-1 after curative chemoradiotherapy in patients with locoregionally advanced squamous cell carcinoma of the head and neck: Reanalysis of the ACTS-HNC study. ( Beppu, T; Fujii, M; Hanamure, Y; Hasegawa, Y; Higaki, Y; Iwae, S; Kawabata, K; Kohno, N; Kubota, A; Nagahara, K; Nakatani, E; Nakatani, H; Taguchi, T; Takemura, H; Terada, T; Teramukai, S; Tomita, K; Tsukahara, K; Yoshino, K, 2018) |
| "Irinotecan was supplied at doses of 40, 50, 60, and 70 mg/m(2) by using a standard 3+3 design." | 2.82 | Cisplatin/Tegafur/Uracil/Irinotecan Triple Combination Therapy for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma: A Phase I/II Clinical Study. ( Chang, PM; Chen, SC; Yang, MH, 2016) |
| "Eligible patients had T1b or T2 glottic squamous cell carcinomas." | 2.80 | Critical evaluation of a prospective study of concurrent chemoradiotherapy with S-1 for early glottic carcinoma. ( Fujimoto, Y; Hiramatsu, M; Itoh, J; Itoh, Y; Kawamura, M; Kimura, K; Kubota, S; Naganawa, S; Nakahara, R; Okada, T; Shibata, T, 2015) |
| " S-1 dosage was started at level 1 (55." | 2.79 | A phase I study of concurrent chemoradiotherapy using oral s-1 for head and neck cancer. ( Fujimoto, Y; Itoh, Y; Kato, S; Naganawa, S; Nakashima, T, 2014) |
| " Pharmacokinetic parameters of S-1 granule did not differ from the capsula formulation." | 2.78 | Phase I pharmacokinetic study of S-1 granules and nedaplatin for advanced head and neck cancer. ( Doi, K; Fujisaka, Y; Hayashi, H; Kawakami, H; Nakagawa, K; Nishimura, Y; Nishina, S; Okamoto, I; Okamoto, K; Satoh, T; Takeda, M; Tanaka, K; Terao, K; Ueda, S, 2013) |
| "Deleterious oral mucositis (OM) develops during radiotherapy (RT) or chemoradiotherapy for head-and-neck cancer (HNC) patients." | 2.77 | Phenylbutyrate mouthwash mitigates oral mucositis during radiotherapy or chemoradiotherapy in patients with head-and-neck cancer. ( Chung, YL; Jen, YM; Lin, YH; Wang, LW; Yen, SH, 2012) |
| "The survival rate of patients with squamous cell carcinoma of the head and neck was 59." | 2.74 | Outpatient chemotherapy with S-1 for recurrent head and neck cancer. ( Shinden, S; Shiotani, A; Watabe, T; Yamashita, T, 2009) |
| "To test the efficacy and safety of pharmacokinetic modulating chemotherapy combined with cisplatin (PMC-cisplatin) as induction chemotherapy (ICT) before definitive treatment in patients with respectable locally advanced head and neck squamous cell carcinoma (HNSCC)." | 2.73 | Effectiveness of pharmacokinetic modulating chemotherapy combined with cisplatin as induction chemotherapy in resectable locally advanced head and neck cancer: phase II study. ( Chang, PM; Chang, SY; Chen, PM; Chu, PY; Huang, JL; Tai, SK; Tsai, TL; Wang, LW; Wang, YF; Yang, MH, 2008) |
| " In total, 79 courses were administered with a median of 3 (range 1-6)." | 2.72 | UFT in combination with oxaliplatin: clinical phase I study in patients with advanced or metastatic solid tumors. ( Abad, A; Aranda, E; Carrato, A; Díaz-Rubio, E; Gallego, J; Gómez, A; López, E; Manzano, JL; Sastre, J, 2006) |
| " Therapy was therefore designed with an oral drug daily given in combination with RT in order to determine the efficacy and toxicity." | 2.71 | [Radiotherapy in combination with low-dose chemotherapy in locally advanced head and neck cancer]. ( Molnár, J; Nagy, B; Paczona, R; Rovó, L; Thurzó, L, 2004) |
| "For locally unresectable recurrent squamous cell carcinoma of the head and neck, we investigated two salvage chemotherapy regimens as second-line chemotherapy." | 2.69 | Prognosis after salvage chemotherapy for locally unresectable recurrent squamous cell carcinoma of the head and neck. ( Kawaida, M; Kitahara, S; Kohno, N; Ohmuma, T, 1999) |
| "Forty-two patients with head and neck cancer were treated with tegafur suppository for 7 days preoperatively and clinical value of this treatment was assessed." | 2.68 | [High tissue concentration of 5-FU reduced local recurrence after administration of tegafur suppositories]. ( Itokazu, T; Kochi, A; Koja, S; Maeda, H; Maeshiro, N; Matsumura, J; Noda, Y; Yasuda, S, 1995) |
| "In an ongoing trial of advanced breast cancer, preliminary results indicate that the combination of idarubicin, UFT, and leucovorin is active, with moderate, primarily hematologic toxicity." | 2.68 | Experience of Oncopaz Cooperative Group with oral fluoropyrimidines in tumors of the stomach, lung, head and neck, and breast. ( Belón, J; Blanco, E; Espinosa, E; Feliu, J; Garcia Alfonso, P; Garcia Girón, C; Garrido, P; González Barón, M; Jara, C; Ruiz, A; Vincent, JM; Zamora, P, 1997) |
| "Most head and neck carcinomas are squamous cell carcinomas (HNSCCs)." | 2.43 | [Clinical efficacy of administration with S-1 alone for head and neck carcinoma]. ( Horiuchi, C; Ishitoya, J; Katori, H; Matsuda, H; Mikami, Y; Taguchi, T; Toth, G; Tsukuda, M; Yoshida, T, 2006) |
| "Most cases of head and neck squamous cell carcinoma (HNSCC) are in the advanced stages, resulting in a poor prognosis." | 2.43 | [Adjuvant chemotherapy with S-1 for advanced head and neck carcinoma]. ( Horiuchi, C; Ishitoya, J; Katori, H; Matsuda, H; Mikami, Y; Taguchi, T; Toth, G; Tsukuda, M; Yoshida, T, 2006) |
| "Comparative clinical studies of head and neck cancer have not provided good evidence, with the exception of an RCT of adjuvant chemotherapy with UFT, in the past." | 2.41 | [Comparative clinical studies for head and neck cancer in Japan]. ( Fujii, M, 2002) |
| "The common clinical presentations of head and neck cancer include early (stage I or II) disease, locally or regionally advanced (stage III or IV, M0) disease, and recurrent or metastatic disease (< 5% of patients)." | 2.40 | Oral 5-FU alternatives for the treatment of head and neck cancer. ( Brockstein, BE; Haraf, DJ; Humerickhouse, R; Vokes, EE, 1998) |
| "However, its efficacy in treating advanced head and neck neoplasms has not been reported." | 1.51 | Apatinib and S-1 combination therapy for the treatment of advanced head and neck neoplasms: Three case reports. ( Han, X; Huang, G; Li, W; Meng, M; Ni, Y; Wang, J; Wei, Z; Yang, X; Ye, X, 2019) |
| " We analyzed the clinical response, survival rate, acute adverse events, and late swallowing toxicity." | 1.51 | Long-term efficacy and toxicity of concurrent chemoradiotherapy with nedaplatin and S-1 for head and neck squamous cell carcinoma. ( Ohashi, T; Ohnishi, M; Okuda, H; Takada, N; Takagi, C; Takahashi, H, 2019) |
| "The involvement of S-1 chemotherapy in ATLL development suggests that a test for HTLV-1 antibody should be performed before treatment and that S-1 should not be administered in HTLV-1 positive patients with head and neck carcinoma." | 1.46 | Adult T-cell leukemia/lymphoma in patients with head and neck cancer after S-1 chemotherapy. ( Kurono, Y; Matushita, K; Nagano, H, 2017) |
| "Our analysis suggests that cancer of the oropharynx and CRT are important risk factors for severe OM in HNC patients that undergo RT or CRT involving S-1." | 1.46 | Analysis of the Risk Factors for Severe Oral Mucositis in Head and Neck Cancer after Chemoradiotherapy with S-1. ( Fujii, N; Hashimoto, T; Kogo, M; Nagatani, A; Naito, Y; Ogawa, Y; Okabe, T; Sasaki, T; Sunaga, T; Tomura, K, 2017) |
| " Severe adverse events were observed in 22 patients (91." | 1.42 | Feasibility and toxicity of adjuvant chemotherapy using S-1 granules for local advanced squamous cell carcinoma of the head and neck. ( Honda, K; Ishikawa, K; Sato, T; Suzuki, S; Yamazaki, K, 2015) |
| "Although the management of oral mucositis is essential to improve treatment completion rates, no detailed studies on the time of oral mucositis appearance have been reported." | 1.40 | [The timing of the appearance of oral mucositis induced by concurrent chemoradiotherapy with S-1 for head and neck cancer]. ( Futagami, K; Nakagawa, T; Nomoto, S; Ogata, K; Takase, H; Tokunaga, S; Yonekita, H; Yoshimitsu, K, 2014) |
| "Choroidal or cutaneous metastasis of gastric cancer is rare." | 1.39 | Choroidal and cutaneous metastasis from gastric adenocarcinoma. ( Ezaki, H; Hayashi, Y; Iijima, H; Kawai, S; Miyazaki, M; Nakai, K; Nishida, K; Nishida, T; Shinzaki, S; Takehara, T; Tsujii, M; Watabe, K; Yakushijin, T; Yamada, T, 2013) |
| " The main adverse events were hematological toxicity, mucositis and dermatitis." | 1.37 | Efficacy and toxicity of concurrent chemoradiotherapy with nedaplatin and S-1 for head and neck cancer. ( Murai, M; Ohashi, T; Ohnishi, M; Tanahashi, S, 2011) |
| "Complications of esophageal cancer are particularly frequent in cases of hypopharyngeal cancer in comparison to other head and neck tumors." | 1.36 | [Effects of concurrent S-1, nedaplatin/radiation therapy for 5 cases of head and neck cancer with esophageal carcinoma]. ( Egawa, S; Furuya, A; Kobayashi, S; Mori, T; Ono, T; Sanbe, T; Shimane, T; Suzaki, H, 2010) |
| "Patients with residual tumors after the initial treatment had a response rate of 47." | 1.36 | [Results of chemotherapy in head and neck cancer patients with residual or recurrent tumors after initial treatment]. ( Katsuno, M; Sato, N; Sugio, Y; Tachibana, S; Tani, Y; Watanabe, N; Zusho, H, 2010) |
| "Thirteen patients with squamous cell carcinoma (SCC) and 3 patients with non-SCC who had recurrent/metastatic disease received S-1 monotherapy as outpatients." | 1.35 | Safety and efficacy of S-1 chemotherapy in recurrent/metastatic head and neck cancer. ( Ishikawa, K; Suzuki, S, 2009) |
| "We report two head and neck cancer patients who responded to TS-1." | 1.32 | [Two head and neck cancer patients who responded to chemotherapy consisting of only TS-1]. ( Horiuchi, C; Kagesato, Y; Kawai, S; Mikami, Y; Mochimatsu, I; Tanigaki, Y; Tsukuda, M, 2003) |
| "Fifty patients with head and neck cancer were treated with tegafur suppository for 7 days preoperatively." | 1.29 | [Tissue concentration of tegafur suppository in patients with head and neck cancer--concentration of 5-FU in cancer tissue]. ( Esu, H; Itokazu, T; Kamiya, S; Kanazawa, T; Koja, S; Maeshiro, N; Noda, Y; Simoji, Y; Yamauchi, M, 1994) |
| "Tegafur (Ftorafur) is an analog of 5-fluorouracil, and its oral form is well absorbed." | 1.28 | Phase II trial of cisplatin and tegafur (Ftorafur) as initial therapy in squamous-cell carcinoma of the head and neck. ( Garcia-Giron, C; Garrido, P; Gavilan, J; Gonzalez-Baron, M; Martin, G; Martorell, V; Tomas, M; Vicente, J; Zamora, P, 1990) |
| "Thirty-one patients with head and neck cancer were administered pretreatment induction chemotherapy (so-called neo-adjuvant chemotherapy) consisting of a UFT and ADM combination." | 1.27 | [Neo-adjuvant chemotherapy with UFT and adriamycin in head and neck cancer]. ( Hyo, N; Imura, S; Kishimoto, M; Kumoi, T; Ogasawara, H; Toda, K, 1987) |
| "Forty cases with head and neck cancer were entered in the trial, of which 37 were perfectly evaluable." | 1.27 | [A phase II study of Futraful suppository in head and neck cancer]. ( Furuta, S; Hanada, T; Kamachi, S; Katsuta, K; Matsumura, M; Matsunaga, S; Moriyama, I; Nobori, T; Ohyama, M; Uchizono, A, 1988) |
| "A Phase II study of UFT for head and neck cancer was conducted in 10 institutions." | 1.27 | [Phase II study of UFT for head and neck cancer]. ( Fujii, M; Hirokawa, T; Horiuchi, M; Inuyama, Y; Kaneko, S; Miyake, H; Ooyama, W; Takeda, C; Tanaka, J; Uchida, M, 1985) |
| "Thyroid cancer, nasal cancer and paranasal sinus cancer gave the best results." | 1.27 | [Chemotherapy with FT-207 suppository (Futraful Supo) in head and neck cancer--cooperative studies by six medical schools in Kanagawa Prefecture]. ( Hattori, Y; Horiuchi, M; Miyake, H; Murakami, T; Otake, H; Sawaki, S; Takahashi, H; Takeyama, I; Tamamushi, N; Yao, K, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (11.45) | 18.7374 |
| 1990's | 26 (19.85) | 18.2507 |
| 2000's | 44 (33.59) | 29.6817 |
| 2010's | 44 (33.59) | 24.3611 |
| 2020's | 2 (1.53) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshino, K | 3 |
| Okamoto, I | 2 |
| Sato, H | 1 |
| Okada, T | 2 |
| Tokashiki, K | 1 |
| Kondo, T | 1 |
| Tsukahara, K | 5 |
| Nishio-Nagai, M | 1 |
| Suzuki, S | 4 |
| Yoshikawa, K | 1 |
| Ueda, R | 1 |
| Kazaoka, Y | 1 |
| Kubota, A | 5 |
| Nakatani, E | 1 |
| Hasegawa, Y | 6 |
| Takemura, H | 3 |
| Terada, T | 2 |
| Taguchi, T | 10 |
| Nagahara, K | 2 |
| Nakatani, H | 2 |
| Higaki, Y | 3 |
| Iwae, S | 3 |
| Beppu, T | 2 |
| Hanamure, Y | 2 |
| Tomita, K | 3 |
| Kohno, N | 12 |
| Kawabata, K | 2 |
| Teramukai, S | 2 |
| Fujii, M | 16 |
| Meng, M | 1 |
| Ye, X | 1 |
| Yang, X | 1 |
| Huang, G | 1 |
| Wei, Z | 1 |
| Ni, Y | 1 |
| Li, W | 1 |
| Han, X | 1 |
| Wang, J | 1 |
| Wakasaki, T | 1 |
| Yasumatsu, R | 3 |
| Uchi, R | 1 |
| Taura, M | 1 |
| Matsuo, M | 1 |
| Komune, N | 1 |
| Nakagawa, T | 3 |
| Okuda, H | 1 |
| Ohnishi, M | 2 |
| Takahashi, H | 3 |
| Takagi, C | 1 |
| Takada, N | 1 |
| Ohashi, T | 2 |
| Bae, WK | 1 |
| Hwang, JE | 1 |
| Shim, HJ | 1 |
| Cho, SH | 1 |
| Lee, KH | 1 |
| Han, HS | 1 |
| Song, EK | 1 |
| Yun, HJ | 1 |
| Cho, IS | 1 |
| Lee, JK | 1 |
| Lim, SC | 1 |
| Chung, WK | 1 |
| Chung, IJ | 1 |
| Kawai, S | 2 |
| Nishida, T | 1 |
| Hayashi, Y | 1 |
| Ezaki, H | 1 |
| Yamada, T | 1 |
| Shinzaki, S | 1 |
| Miyazaki, M | 1 |
| Nakai, K | 1 |
| Yakushijin, T | 1 |
| Watabe, K | 1 |
| Iijima, H | 1 |
| Tsujii, M | 1 |
| Nishida, K | 1 |
| Takehara, T | 1 |
| Maeda, M | 1 |
| Yamashita, T | 3 |
| Matsunobu, T | 1 |
| Araki, K | 2 |
| Tomifuji, M | 1 |
| Shiotani, A | 2 |
| Hayashi, H | 1 |
| Ueda, S | 1 |
| Tanaka, K | 2 |
| Okamoto, K | 1 |
| Kawakami, H | 1 |
| Nishina, S | 1 |
| Takeda, M | 1 |
| Fujisaka, Y | 1 |
| Satoh, T | 1 |
| Terao, K | 2 |
| Nishimura, Y | 1 |
| Doi, K | 1 |
| Nakagawa, K | 1 |
| Fujimoto, Y | 2 |
| Kato, S | 1 |
| Itoh, Y | 2 |
| Naganawa, S | 2 |
| Nakashima, T | 5 |
| Sato, D | 2 |
| Kogashiwa, Y | 4 |
| Yamauchi, K | 3 |
| Hoshikawa, H | 1 |
| Kishino, T | 1 |
| Mori, T | 2 |
| Indo, K | 1 |
| Inamoto, R | 1 |
| Akiyama, K | 1 |
| Miyashita, T | 1 |
| Mori, N | 1 |
| Yonekita, H | 1 |
| Takase, H | 1 |
| Ogata, K | 1 |
| Futagami, K | 1 |
| Nomoto, S | 1 |
| Yoshimitsu, K | 1 |
| Tokunaga, S | 1 |
| Moro, Y | 1 |
| Matsumoto, Y | 1 |
| Nakamura, T | 1 |
| Sakurai, H | 1 |
| Fukushima, M | 1 |
| Yamauchi, M | 2 |
| Toh, S | 1 |
| Komune, S | 2 |
| Tahara, M | 6 |
| Kiyota, N | 3 |
| Mizusawa, J | 1 |
| Nakamura, K | 4 |
| Hayashi, R | 4 |
| Akimoto, T | 3 |
| Monden, N | 1 |
| Matsuura, K | 2 |
| Fujii, H | 1 |
| Onozawa, Y | 2 |
| Homma, A | 3 |
| Fukuda, H | 2 |
| Kimura, K | 1 |
| Nakahara, R | 1 |
| Kawamura, M | 1 |
| Kubota, S | 1 |
| Itoh, J | 1 |
| Hiramatsu, M | 1 |
| Shibata, T | 1 |
| Honda, K | 1 |
| Sato, T | 1 |
| Yamazaki, K | 2 |
| Ishikawa, K | 4 |
| Hirai, M | 1 |
| Orita, Y | 1 |
| Takao, S | 1 |
| Tachibana, T | 1 |
| Marunaka, H | 1 |
| Makihara, S | 1 |
| Miki, K | 1 |
| Noyama, Y | 1 |
| Fuji, S | 1 |
| Torigoe, A | 1 |
| Sato, Y | 1 |
| Nishizaki, K | 1 |
| Kim, HR | 2 |
| Lee, CG | 1 |
| Choi, EC | 2 |
| Kim, JH | 2 |
| Koh, YW | 2 |
| Cho, BC | 2 |
| Chen, SC | 1 |
| Chang, PM | 2 |
| Yang, MH | 2 |
| Sato, M | 1 |
| Nakano, T | 1 |
| Kogo, R | 1 |
| Hashimoto, K | 2 |
| Sawatsubashi, M | 1 |
| Nagano, H | 2 |
| Kurono, Y | 1 |
| Matushita, K | 1 |
| Nagatani, A | 1 |
| Ogawa, Y | 1 |
| Sunaga, T | 1 |
| Tomura, K | 1 |
| Naito, Y | 1 |
| Fujii, N | 1 |
| Okabe, T | 1 |
| Hashimoto, T | 1 |
| Kogo, M | 1 |
| Sasaki, T | 2 |
| Yamazaki, T | 1 |
| Enokida, T | 1 |
| Wakasugi, T | 1 |
| Arahira, S | 1 |
| Zenda, S | 2 |
| Motegi, A | 1 |
| Yoshisue, K | 1 |
| Tsukuda, M | 17 |
| Ishitoya, J | 4 |
| Mikami, Y | 4 |
| Matsuda, H | 5 |
| Horiuchi, C | 5 |
| Satake, K | 3 |
| Kawano, T | 2 |
| Takahashi, M | 1 |
| Nishimura, G | 3 |
| Kawakami, M | 2 |
| Sakuma, Y | 1 |
| Watanabe, M | 2 |
| Shiono, O | 1 |
| Komatsu, M | 2 |
| Yamashita, Y | 1 |
| Shirasaki, T | 1 |
| Maruya, S | 1 |
| Namba, A | 1 |
| Matsubara, A | 1 |
| Shinkawa, H | 1 |
| Shinden, S | 1 |
| Watabe, T | 1 |
| Fesneau, M | 1 |
| Pointreau, Y | 1 |
| Chapet, S | 1 |
| Martin, L | 1 |
| Pommier, P | 1 |
| Alfonsi, M | 1 |
| Laguerre, B | 1 |
| Feham, N | 1 |
| Berger, C | 1 |
| Garaud, P | 1 |
| Calais, G | 1 |
| Boku, N | 2 |
| Abo, H | 1 |
| Niho, T | 1 |
| Nishijima, W | 1 |
| Yamane, H | 1 |
| Tomita, T | 1 |
| Yoon, DH | 2 |
| Kim, SB | 2 |
| Okano, S | 1 |
| Fuse, N | 1 |
| Minashi, K | 1 |
| Yoshino, T | 1 |
| Doi, T | 1 |
| Kawashima, M | 2 |
| Ogino, T | 2 |
| Minami, H | 2 |
| Ohtsu, A | 2 |
| Shimane, T | 1 |
| Ono, T | 2 |
| Egawa, S | 1 |
| Furuya, A | 1 |
| Kobayashi, S | 2 |
| Sanbe, T | 2 |
| Suzaki, H | 1 |
| Cho, Y | 1 |
| Kim, SY | 1 |
| Nam, SY | 1 |
| Choi, SH | 1 |
| Roh, JL | 1 |
| Lee, SW | 1 |
| Song, SY | 1 |
| Lee, JH | 1 |
| Kim, JS | 1 |
| Cho, KJ | 1 |
| Shinoto, M | 1 |
| Shioyama, Y | 2 |
| Ohura, H | 1 |
| Toh, Y | 1 |
| Yamaguchi, T | 1 |
| Ohnishi, K | 1 |
| Atsumi, K | 1 |
| Hirata, H | 1 |
| Honda, H | 1 |
| Katsuno, M | 2 |
| Watanabe, N | 1 |
| Sugio, Y | 1 |
| Tachibana, S | 2 |
| Tani, Y | 1 |
| Sato, N | 1 |
| Zusho, H | 1 |
| Nagafuji, H | 2 |
| Matsuda, T | 2 |
| Tsubosaka, T | 1 |
| Karaho, T | 1 |
| Maruyama, T | 1 |
| Tanahashi, S | 1 |
| Murai, M | 1 |
| Kawada, K | 1 |
| Mukai, H | 1 |
| Sakuraba, M | 1 |
| Furusaka, T | 1 |
| Tanaka, A | 1 |
| Ikeda, M | 1 |
| Kawaguchi, K | 1 |
| Sato, K | 1 |
| Yamada, H | 1 |
| Horie, A | 1 |
| Nomura, T | 1 |
| Iketani, S | 1 |
| Kanai, I | 1 |
| Nakatani, Y | 1 |
| Hamada, Y | 1 |
| Yen, SH | 1 |
| Wang, LW | 2 |
| Lin, YH | 1 |
| Jen, YM | 1 |
| Chung, YL | 1 |
| Yokota, T | 1 |
| Hamauchi, S | 1 |
| Tsushima, T | 1 |
| Taniguchi, H | 1 |
| Todaka, A | 1 |
| Machida, N | 1 |
| Fukutomi, A | 1 |
| Yasui, H | 1 |
| Kim, HS | 2 |
| Kim, GM | 1 |
| Kim, SH | 1 |
| Hong, YK | 1 |
| Sung, JH | 1 |
| Kim, SM | 1 |
| Yamamoto, Y | 1 |
| Nakai, N | 1 |
| Wakabayashi, Y | 1 |
| Okuzawa, Y | 1 |
| Asai, J | 1 |
| Takenaka, H | 2 |
| Katoh, N | 1 |
| Nakata, K | 1 |
| Sakata, K | 1 |
| Someya, M | 1 |
| Miura, K | 1 |
| Hayashi, J | 1 |
| Hori, M | 1 |
| Takagi, M | 1 |
| Himi, T | 1 |
| Kondo, A | 1 |
| Hareyama, M | 1 |
| Wang, HM | 2 |
| Wang, CS | 1 |
| Chen, JS | 2 |
| Chen, IH | 2 |
| Liao, CT | 2 |
| Chang, TC | 2 |
| Nishino, H | 2 |
| Shinozaki, T | 1 |
| Tanaka, H | 2 |
| Ichimura, K | 1 |
| Kagesato, Y | 1 |
| Tanigaki, Y | 1 |
| Mochimatsu, I | 1 |
| Furukawa, M | 1 |
| Nagy, B | 1 |
| Molnár, J | 1 |
| Rovó, L | 1 |
| Paczona, R | 1 |
| Thurzó, L | 1 |
| Liaw, CC | 1 |
| Tsang, NM | 1 |
| Kuratomi, Y | 1 |
| Yamamoto, T | 1 |
| Masuda, M | 1 |
| Hirakawa, N | 1 |
| Umezaki, T | 2 |
| Kida, A | 4 |
| Kono, N | 2 |
| Yoshihara, T | 2 |
| Sugita, M | 3 |
| Asano, R | 1 |
| Morimoto, M | 1 |
| Kubota, H | 1 |
| Iida, M | 1 |
| Kadokura, Y | 1 |
| Watanabe, A | 2 |
| Taniguchi, M | 2 |
| Ueda, M | 1 |
| Abe, T | 1 |
| Kusumi, T | 1 |
| Hosokawa, M | 1 |
| Sasaki, S | 1 |
| Nakanome, A | 1 |
| Shiga, K | 1 |
| Sagai, S | 1 |
| Ogawa, T | 1 |
| Kobayashi, T | 2 |
| Sastre, J | 1 |
| Aranda, E | 1 |
| Abad, A | 1 |
| Gallego, J | 1 |
| Manzano, JL | 1 |
| Gómez, A | 1 |
| Carrato, A | 1 |
| López, E | 1 |
| Díaz-Rubio, E | 2 |
| Itoi, A | 1 |
| Takashima, M | 1 |
| Ishimasa, H | 1 |
| Murata, H | 1 |
| Tomoda, K | 1 |
| Katori, H | 3 |
| Yoshida, T | 3 |
| Toth, G | 2 |
| Ito, H | 1 |
| Tokashiki, R | 1 |
| Shimizu, A | 1 |
| Hiramatsu, H | 1 |
| Funato, N | 1 |
| Tsujie, H | 1 |
| Kawasaki, M | 1 |
| Watanabe, K | 1 |
| Watanabe, J | 1 |
| Rivera, F | 2 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicenter Phase II Study of Weekly Docetaxel, Cisplatin, and S-1 (TPS) Induction Chemotherapy in Locally Advanced Squamous Cell Cancer of the Head and Neck[NCT01645748] | Phase 2 | 35 participants (Actual) | Interventional | 2008-10-31 | Completed | ||
| Controlled Randomized Trial to Evaluate Efficacy of Adjuvant Chemotherapy Between S-1 and UFT for Locally Advanced Squamous Cell Carcinoma of the Head and Neck: Phase III Study[NCT00336947] | Phase 3 | 500 participants (Anticipated) | Interventional | 2006-04-30 | Active, not recruiting | ||
| A Phase Ib/II Study of Ramucirumab (Cyramza®), Nal-IRI (ONIVYDE®) and Trifluridine/Tipiracil (Lonsurf®) in Second Line Metastatic Gastric Cancer (COOL Study).[NCT05927857] | Phase 1/Phase 2 | 45 participants (Anticipated) | Interventional | 2023-09-01 | Not yet recruiting | ||
| PhaseⅡSingle-center, Open-label, Exploratory Clinical Study of Apatinib in Combination With S1 for the Patients With Advanced Non-squamous Head and Neck Cancer[NCT02943252] | Phase 2 | 30 participants (Anticipated) | Interventional | 2016-10-31 | Recruiting | ||
| A Prospective, Single-arm Study of Simultaneous Modulated Accelerated Radiotherapy Combined With S-1/DDP for Elderly Esophageal Squamous Cell Carcinoma.[NCT02606916] | Phase 2 | 42 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| A Phase II Study of Maintenance Tegafur-uracil in Patients With Squamous Cell Carcinoma of Oral Cavity With Extracapsular Spreading of Lymph Nodes[NCT03121313] | Phase 2 | 68 participants (Anticipated) | Interventional | 2015-02-26 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for tegafur and Cancer of Head
| Article | Year |
|---|---|
S-1 plus cisplatin: another option in the treatment of advanced head and neck cancer?
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; | 2010 |
[Comparative clinical studies for head and neck cancer in Japan].
Topics: Antineoplastic Agents; Carboplatin; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Com | 2002 |
[Clinical efficacy of administration with S-1 alone for head and neck carcinoma].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol | 2006 |
[Combination therapy with S-1 and CDDP for head and neck cancer].
Topics: Adult; Aged; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinom | 2006 |
[Adjuvant chemotherapy with S-1 for advanced head and neck carcinoma].
Topics: Anorexia; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Drug Ad | 2006 |
[Head and neck cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Ci | 1996 |
The role of chemotherapy in the treatment of head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemotherapy, | 1997 |
Future directions in the treatment of squamous cell carcinoma of the head and neck: the role of UFT.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Che | 1997 |
Oral 5-FU alternatives for the treatment of head and neck cancer.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol | 1998 |
Oral fluoropyrimidines in cancer treatment.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Colo | 2000 |
[New oral anticancer drug, TS-1 (S-1)--from bench to clinic].
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Clinical Trials as Topic; Colorectal | 2001 |
52 trials available for tegafur and Cancer of Head
| Article | Year |
|---|---|
Adjuvant chemotherapy with S-1 after curative chemoradiotherapy in patients with locoregionally advanced squamous cell carcinoma of the head and neck: Reanalysis of the ACTS-HNC study.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemor | 2018 |
Multicenter phase II study of weekly docetaxel, cisplatin, and S-1 (TPS) induction chemotherapy for locally advanced squamous cell cancer of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squam | 2013 |
Phase I pharmacokinetic study of S-1 granules and nedaplatin for advanced head and neck cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Combinations; F | 2013 |
A phase I study of concurrent chemoradiotherapy using oral s-1 for head and neck cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Carcinoma, Squamous Cell; Chemoradiotherapy; Dose | 2014 |
Phase I study of nedaplatin prior to S-1 in patients with locally advanced head and neck squamous cell carcinoma.
Topics: Administration, Oral; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Administration Sch | 2013 |
Randomized phase III trial of adjuvant chemotherapy with S-1 after curative treatment in patients with squamous-cell carcinoma of the head and neck (ACTS-HNC).
Topics: Adult; Aged; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Drug Combinations; Female; Head and N | 2015 |
Phase II trial of chemoradiotherapy with S-1 plus cisplatin for unresectable locally advanced head and neck cancer (JCOG0706).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; C | 2015 |
Critical evaluation of a prospective study of concurrent chemoradiotherapy with S-1 for early glottic carcinoma.
Topics: Aged; Carcinoma, Squamous Cell; Chemoradiotherapy; Combined Modality Therapy; Drug Combinations; Fem | 2015 |
How long should we continue S-1 as adjuvant chemotherapy for squamous cell carcinoma of the head and neck?
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Sq | 2015 |
Cisplatin/Tegafur/Uracil/Irinotecan Triple Combination Therapy for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma: A Phase I/II Clinical Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Squamous Cell; | 2016 |
Pharmacokinetics of initial full and subsequent reduced doses of S-1 in patients with locally advanced head and neck cancer-effect of renal insufficiency.
Topics: Aged; Area Under Curve; Cisplatin; Dose-Response Relationship, Drug; Drug Combinations; Female; Head | 2017 |
Outpatient chemotherapy with S-1 for recurrent head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap | 2009 |
Concomitant chemoradiotherapy using carboplatin, tegafur-uracil and leucovorin for stage III and IV head-and-neck cancer: results of GORTEC Phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; | 2010 |
Phase II trial of concurrent chemoradiotherapy with S-1 plus cisplatin in patients with unresectable locally advanced squamous cell carcinoma of the head and neck: Japan Clinical Oncology Group Study (JCOG0706).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co | 2009 |
Phase I/II study of s-1 plus cisplatin combination chemotherapy in patients with advanced/recurrent head and neck cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2010 |
Phase I trial of combination chemotherapy with docetaxel, cisplatin and S-1 (TPS) in patients with locally advanced or recurrent/metastatic head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Dose-Response Rel | 2011 |
Phase I study of S-1 plus nedaplatin in patients with advanced/recurrent head and neck cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell; Cisplatin | 2010 |
Phase I trial of chemoradiotherapy with the combination of S-1 plus cisplatin for patients with unresectable locally advanced squamous cell carcinoma of the head and neck.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Capsul | 2011 |
Phenylbutyrate mouthwash mitigates oral mucositis during radiotherapy or chemoradiotherapy in patients with head-and-neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cisplatin; Double-Blind Method; E | 2012 |
Feasibility of concurrent chemoradiotherapy with S-1 administered on alternate days for elderly patients with head and neck cancer.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemoradiotherap | 2012 |
Phase I study of oral S-1 and concurrent radiotherapy in patients with head and neck cancer.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anorexia; Antimetabolites, Antineoplastic; Carcinoma, | 2013 |
Cisplatin, tegafur, and leucovorin: a moderately effective and minimally toxic outpatient neoadjuvant chemotherapy for locally advanced squamous cell carcinoma of the head and neck.
Topics: Administration, Oral; Adult; Aged; Ambulatory Care Facilities; Antineoplastic Combined Chemotherapy | 2002 |
[Radiotherapy in combination with low-dose chemotherapy in locally advanced head and neck cancer].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, | 2004 |
[Phase I study of concurrent radiotherapy with TS-1 and vitamin A (TAR Therapy) for head and neck cancer].
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Dru | 2005 |
Randomized scheduling feasibility study of S-1 for adjuvant chemotherapy in advanced head and neck cancer.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemot | 2005 |
[Clinical phase trial of concurrent chemoradiotherapy combined TS-1 and nedaplatin].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 2005 |
Phase I/II study of S-1 combined with carboplatin in recurrent and/or metastatic head and neck cancer as outpatient chemotherapy.
Topics: Adult; Aged; Ambulatory Care; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy | 2006 |
UFT in combination with oxaliplatin: clinical phase I study in patients with advanced or metastatic solid tumors.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, | 2006 |
[Adjuvant chemotherapy with TS-1 for head and neck cancer--side effect of two-week application followed by one-week rest regimen].
Topics: Administration, Oral; Aged; Aged, 80 and over; Anemia, Megaloblastic; Antimetabolites, Antineoplasti | 2006 |
[Combination chemotherapy with S-1 and carboplatin for head and neck cancers].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; | 2006 |
[Concurrent chemoradiotherapy (CRT) with S-1 and cisplatin (CDDP) in patients (pts) with locally advanced head and neck cancer (HNC)].
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cispl | 2006 |
Long term results of a phase II trial of induction chemotherapy with uracil-ftegafur (UFT), vinorelbine and cisplatin (UFTVP) followed by radiotherapy concomitant with UFT and carboplatin (RT/UFTJ) in non-resectable locally advanced (stage IV-B) squamous
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Car | 2007 |
Concurrent chemoradiotherapy with carboplatin and uracil-f tegafur (UFT) for patients with poor performance status with locally advanced squamous cell carcinoma of the head and neck (SCCHN).
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; F | 2007 |
Randomized phase II study of cisplatin and 5-FU continuous infusion (PF) versus cisplatin, UFT and vinorelbine (UFTVP) as induction chemotherapy in locally advanced squamous cell head and neck cancer (LA-SCHNC).
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Disease-Free Su | 2008 |
Effectiveness of pharmacokinetic modulating chemotherapy combined with cisplatin as induction chemotherapy in resectable locally advanced head and neck cancer: phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co | 2008 |
Clinical trials with oral Futraful (INN: Tegafur) in cancer of the head and neck.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Adenoid Cystic; Car | 1981 |
[High tissue concentration of 5-FU reduced local recurrence after administration of tegafur suppositories].
Topics: Chemotherapy, Adjuvant; Fluorouracil; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Neoplas | 1995 |
[A prospective randomized trial of adjuvant chemotherapy with UFT for head and neck carcinoma. Head and Neck UFT Study Group].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamo | 1994 |
A trial of individual dose intensity and relative performance factors in tegafur maintenance chemotherapy for head and neck cancer.
Topics: Aged; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Survival Rate; Tegafur | 1993 |
[Determination of 5-FU tissue concentrations after oral UFT administration in tumors of the head and neck].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamo | 1996 |
[Combination chemotherapy with 5-FU and CDDP or CDDP analog for head and neck cancer].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squ | 1996 |
Experience of Oncopaz Cooperative Group with oral fluoropyrimidines in tumors of the stomach, lung, head and neck, and breast.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carci | 1997 |
Neoadjuvant therapy with cisplatin/fluorouracil vs cisplatin/UFT in locally advanced squamous cell head and neck cancer.
Topics: Adult; Aged; Alopecia; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous C | 1997 |
[Early phase II study of S-1 in patients with advanced head and neck cancer. S-1 Cooperative Study Group (Head and Neck Working Group)].
Topics: Administration, Oral; Adult; Aged; Anorexia; Antimetabolites, Antineoplastic; Carcinoma, Squamous Ce | 1998 |
[Combined chemotherapy with low-dose cisplatin, tegafur and uracil for head and neck squamous cell carcinomas].
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carci | 1999 |
Prognosis after salvage chemotherapy for locally unresectable recurrent squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dr | 1999 |
UFT/leucovorin in advanced squamous cell carcinoma of the head and neck administered with radiotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 2000 |
A phase II study of combined oral uracil and ftorafur with leucovorin for patients with squamous cell carcinoma of the head and neck.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anemia; Antimetabolites, Antineoplastic; Antin | 2001 |
[Late phase II study of S-1 in patients with advanced head and neck cancer].
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Drug A | 2001 |
Induction chemotherapy with carboplatin and ftorafur in advanced head and neck cancer. A randomized study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; | 1992 |
[Investigation of UFT and radiation combination therapy of head and neck cancer--mainly in laryngeal cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th | 1990 |
Clinical trials on UFT in the treatment of head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Tria | 1985 |
68 other studies available for tegafur and Cancer of Head
| Article | Year |
|---|---|
Effect of Concomitant Lafutidine on Adjuvant S-1 for Head and Neck Cancer: A Comparative Study.
Topics: Acetamides; Adult; Aged; Antimetabolites, Antineoplastic; Drug Combinations; Female; Head and Neck N | 2021 |
Adoptive immunotherapy combined with FP treatment for head and neck cancer: An in vitro study.
Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Prolifera | 2017 |
Apatinib and S-1 combination therapy for the treatment of advanced head and neck neoplasms: Three case reports.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Biopsy; Drug Combinations; Head an | 2019 |
Outcome of chemotherapy following nivolumab treatment for recurrent and/or metastatic head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; C | 2020 |
Long-term efficacy and toxicity of concurrent chemoradiotherapy with nedaplatin and S-1 for head and neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; D | 2019 |
Choroidal and cutaneous metastasis from gastric adenocarcinoma.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Choroid Neoplasms; Cis | 2013 |
Outpatient oral chemotherapy with S-1 for unresectable or distant metastatic head and neck cancer.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Drug C | 2013 |
Clinical outcomes of nedaplatin and S-1 treatment with concurrent radiotherapy in advanced head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemoradiotherapy; | 2015 |
[The timing of the appearance of oral mucositis induced by concurrent chemoradiotherapy with S-1 for head and neck cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Drug Combinations; Female; | 2014 |
Feasibility study of alternate-day S-1 as adjuvant chemotherapy for head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Drug Combinations; Feasibility Studies; Fema | 2015 |
Extrapulmonary small cell carcinoma in head and neck.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Sm | 2015 |
Feasibility and toxicity of adjuvant chemotherapy using S-1 granules for local advanced squamous cell carcinoma of the head and neck.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemot | 2015 |
Induction docetaxel and S-1 followed by concomitant radiotherapy with low-dose daily cisplatin in locally advanced head and neck carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap | 2016 |
Clinical management of squamous cell carcinoma associated with sinonasal inverted papilloma.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemor | 2017 |
Adult T-cell leukemia/lymphoma in patients with head and neck cancer after S-1 chemotherapy.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; C | 2017 |
Analysis of the Risk Factors for Severe Oral Mucositis in Head and Neck Cancer after Chemoradiotherapy with S-1.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Drug Combinations; Female; | 2017 |
Analysis of feasibility and toxicity of concurrent chemoradiotherapy with S-1 for locally advanced squamous cell carcinoma of the head and neck in elderly cases and/or cases with comorbidity.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined | 2009 |
[Treatment results of chemotherapy with S-1 for head and neck cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; F | 2009 |
[Successful treatment results of S-1 administration in 2 patients, one with a remnant tumor of the larynx and metastatic tumors to the lung, and another with a metastatic tumor in the neck from the hypopharynx].
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cel | 2009 |
Safety and efficacy of S-1 chemotherapy in recurrent/metastatic head and neck cancer.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Carcinoma, Adenosquamous; Carcinoma, Sq | 2009 |
[Effects of concurrent S-1, nedaplatin/radiation therapy for 5 cases of head and neck cancer with esophageal carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Combinations; | 2010 |
Usefulness of interim FDG-PET after induction chemotherapy in patients with locally advanced squamous cell carcinoma of the head and neck receiving sequential induction chemotherapy followed by concurrent chemoradiotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell; Ci | 2011 |
Clinical results of definitive chemoradiotherapy for patients with synchronous head and neck squamous cell carcinoma and esophageal cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma, S | 2011 |
[Results of chemotherapy in head and neck cancer patients with residual or recurrent tumors after initial treatment].
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Drug Combinations; Female; Head | 2010 |
Efficacy and toxicity of concurrent chemoradiotherapy with nedaplatin and S-1 for head and neck cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Th | 2011 |
Consecutive daily low-dose S-1 adjuvant chemotherapy after radical treatment for squamous cell carcinoma in head and neck cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemother | 2011 |
Stereotactic radiosurgery in combination with chemotherapy as primary treatment for head and neck cancer.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Proto | 2012 |
S-1 monotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck after progression on platinum-based chemotherapy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Disease-Free Survival; Drug | 2011 |
The efficacy and toxicity of S-1 and cisplatin as first-line chemotherapy in recurrent or metastatic head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dr | 2012 |
A case of advanced cutaneous squamous cell carcinoma of the lower eyelid that was successfully treated with tegafur-gimeracil-oteracil potassium monotherapy.
Topics: Administration, Oral; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; | 2012 |
[Adverse reactions to TS-1 for outpatients with recurrent head and neck cancer].
Topics: Adult; Aged; Ambulatory Care; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Co | 2002 |
[Two head and neck cancer patients who responded to chemotherapy consisting of only TS-1].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Combinations; He | 2003 |
[Nedaplatin for recurrent cancer of the head and neck].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; | 2004 |
Biweekly paclitaxel, cisplatin, tegafur, and leucovorin as neoadjuvant chemotherapy for unresectable squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Fe | 2004 |
[Combination therapy with TS-1].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Cl | 2005 |
[A case report of cancer of the lip--complete response by a neo-adjuvant chemotherapy using a novel method of TS-1 administration].
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Drug Administrati | 2006 |
[A combination study of S-1 and docetaxel in patients with head and neck cancer].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Administration | 2006 |
[TS-1 and irradiation combination therapy for head and neck cancer].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Drug Administration Schedul | 2006 |
Cancer drug trials show modest benefit: drugs target liver, gastric, head and neck cancers.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzenesulfonates; | 2007 |
[Long-term results of S-1 administration as adjuvant chemotherapy for advanced head and neck cancer].
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Disease-Free Survival; Drug Administratio | 2007 |
Induction chemotherapy with S-1 plus cisplatin in patients with locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co | 2008 |
[Adjuvant chemotherapy with S-1 for head and neck carcinoma].
Topics: Chemotherapy, Adjuvant; Drug Combinations; Female; Head and Neck Neoplasms; Humans; Male; Middle Age | 2008 |
[Evaluation of tissue concentrations of FT-207 and 5-FU in head and neck cancer].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Fluorouracil; Head | 1983 |
[Level of 5-FU in tumor tissues of the patients with head and neck malignant tumors after oral administration of UFT].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Fluorourac | 1983 |
[Clinical application of futraful suppositories in malignant head and neck cancer--effects of the therapy combined with radiation].
Topics: Aged; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Suppositories; Tegaf | 1982 |
[Tissue concentration of tegafur suppository in patients with head and neck cancer--concentration of 5-FU in cancer tissue].
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Fluorouracil; Head and Neck Neopla | 1994 |
[The effect of induction chemotherapy with CBDCA, 5-FU and UFT in head and neck cancer].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Drug Admini | 1994 |
[Tissue and serum levels of 5-FU in the patients with head and neck malignant tumors--influence of a streptococcal preparation OK-432].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Head and Neck Neo | 1993 |
[Giant metastatic neck tumor responding to oral administration of UFT--a case report].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; | 1999 |
Therapeutic effect of 1 M tegafur-0.4 M 5-chloro-2, 4-dihydroxypridine-1 M potassium oxonate (S-1) on head and neck squamous carcinoma cells.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy | 2000 |
An experimental model of tumor dormancy therapy for advanced head and neck carcinoma.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Antioxidan | 2000 |
[Evaluation of preoperative simultaneous radiochemotherapy combined with carboplatin and tegafur.uracil].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carbop | 2002 |
[Chemosensitivity of head and neck squamous cell carcinomas using subrenal capsule assay--comparative assay of 5-FU, FT, UFT, and HCFU and immunohistochemical study].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 1992 |
[A comparative study of UFT enteric-coated granules with UFT capsules on the occurrence of side effects in patients with head and neck cancers--a special attention to the upper gastrointestinal tract disorders].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capsules; Diarrhea; | 1990 |
[Usage of urine FT levels for medication compliance in head and neck cancer with administration of UFT].
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; | 1990 |
Phase II trial of carboplatin and tegafur (Ftorafur) as induction therapy in squamous-cell carcinoma of the head and neck.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carc | 1990 |
Phase II trial of cisplatin and tegafur (Ftorafur) as initial therapy in squamous-cell carcinoma of the head and neck.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamo | 1990 |
Cisplatin and tegafur in recurrent head and neck cancer. A phase II study.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamo | 1990 |
[Combined chemotherapy and radiotherapy in recurrent tumors of the head and neck region].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphami | 1987 |
Treatment of advanced and/or metastatic epidermoid carcinoma of the head and neck: an effective combination chemotherapy with bleomycin, methotrexate and ftorafur.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma | 1989 |
Improved results in the treatment of nasopharyngeal carcinoma using combined radiotherapy and chemotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, | 1989 |
[Preoperative chemotherapy for head and neck cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Fluorouracil; Head and Neck Ne | 1985 |
[Influence of OK-432 on the concentration of active substance of fluoropyrimidine carcinostatics in the living body].
Topics: Biological Products; Fluorouracil; Head and Neck Neoplasms; Humans; Picibanil; Tegafur | 1986 |
UFT for head and neck cancers: its tissue concentrations and effects on lymphocyte subpopulations.
Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Combined Modali | 1987 |
[Neo-adjuvant chemotherapy with UFT and adriamycin in head and neck cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 1987 |
[A phase II study of Futraful suppository in head and neck cancer].
Topics: Aged; Anorexia; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Evaluation; Female; | 1988 |
[Phase II study of UFT for head and neck cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Head and Neck | 1985 |
[Chemotherapy with FT-207 suppository (Futraful Supo) in head and neck cancer--cooperative studies by six medical schools in Kanagawa Prefecture].
Topics: Adult; Aged; Anorexia; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Fluorouracil; | 1985 |