tegafur has been researched along with Cancer of Colon in 306 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to determine the maximum tolerated dose, recommended dose and dose-limiting toxicities of irinotecan (CPT-11) plus S-1 in advanced colorectal cancer." | 9.14 | A phase I study of combination therapy with S-1 and irinotecan (CPT-11) in patients with advanced colorectal cancer. ( Akaike, M; Morinaga, S; Shiozawa, M; Sugano, N; Sugimasa, Y; Tsuchida, K, 2009) |
| "We report a case of acute myelogenous leukemia (AML) with MLL (myeloid-lymphoid leukemia or mixed-lineage leukemia) gene rearrangement after exposure to tegafur/uracil." | 7.71 | MLL gene rearrangement in acute myelogenous leukemia after exposure to tegafur/uracil. ( Fukushima, T; Kida, H; Noto, Y; Yoshio, N, 2002) |
| " In a previous study, the authors demonstrated that the combination of uracil and tegafur (UFT) with leucovorin (LV) was active and well tolerated in patients with advanced colorectal carcinoma (ACC)." | 7.69 | Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group. ( Colmenarejo, A; de Castro, J; de la Gándara, I; Espinosa, E; Espinosa, J; Feliu, J; Fernández, Y; García Girón, C; González Barón, M; Jalón, JI, 1997) |
| "Goblet cell carcinoid of the appendix is a rare neoplasm and clinically tends to take a malignant course." | 5.35 | [A case of peritonitis carcinomatosa from goblet cell carcinoid of the appendix treated by intraperitoneal paclitaxel and systemic S-1 chemotherapy]. ( Fujimoto, H; Harada, E; Horiuchi, N; Iwasaka, N; Kashima, M; Kimura, S; Masuda, K; Matsushita, T; Nakamura, S; Oshima, Y; Shichijo, K; Shinomiya, S; Takeichi, T; Tamaki, Y; Yoshida, S, 2008) |
| "Among these patients, 8 developed hyperbilirubinemia." | 5.33 | [Efficacy of the combined use of taurine for hyperbilirubinemia caused by UFT therapy after surgery for colonic cancer]. ( Fujii, K; Iizuka, R; Ikawa, O; Izumi, H; Kakihara, N; Katoh, Y; Matsumura, H; Miyata, K; Ohgaki, M; Shimomura, K; Shimotsuma, M; Tkenaka, A, 2006) |
| "Tegafur was effective, but levamisole with or without tegafur was not effective against early cancer." | 5.27 | Longer survival and fewer metastases by levamisole and tegafur in 1, 2-dimethylhydrazine-induced murine colonic cancers. ( Aoki, N; Hamada, S; Hirayama, R; Matsumura, J; Mishima, Y; Miyanaga, T; Takagi, Y, 1985) |
| "The aim of this study was to determine the maximum tolerated dose, recommended dose and dose-limiting toxicities of irinotecan (CPT-11) plus S-1 in advanced colorectal cancer." | 5.14 | A phase I study of combination therapy with S-1 and irinotecan (CPT-11) in patients with advanced colorectal cancer. ( Akaike, M; Morinaga, S; Shiozawa, M; Sugano, N; Sugimasa, Y; Tsuchida, K, 2009) |
| "In this prospective randomized study the effect of oral Ftorafur was compared with that of intravenous 5-fluorouracil in patients with advanced adenocarcinoma of the stomach, colon or rectum." | 5.06 | Comparison of oral ftorafur and intravenous 5-fluorouracil in patients with advanced cancer of the stomach, colon or rectum. ( Bjerkeset, T; Fjøsne, HE, 1986) |
| "We report a case of a 79-year-old man who developed severe therapy-related pancytopenia from tegafur uracil(UFT)and Leucovorin(LV)as adjuvant chemotherapy for ascending colon cancer." | 3.85 | [Severe Therapy-Related Pancytopenia Caused by UFT and LV in a Patient with Ascending Colon Cancer]. ( Akiyama, T; Harano, R; Iida, A; Imamura, N; Kusashio, K; Matsumoto, M; Ohtsuka, M; Suzuki, T; Udagawa, I; Yasutomi, J; Yoshizumi, A, 2017) |
| "One patient with pulmonary metastasis from colon cancer and one with para-aortic lymph node metastasis were treated with a combination of irinotecan and UFT." | 3.71 | [Two patients with recurrent colon cancer who underwent surgery following a combination of irinotecan and UFT]. ( Ishikawa, K; Maeda, Y; Makuuchi, H; Murayama, C; Sadahiro, S; Saguchi, T; Suzuki, T; Yamamoto, T; Yasuda, S, 2002) |
| " Using a murine dorsal air sac (DAS) assay, we have previously shown that UFT and its metabolites, gamma-hydroxybutyric acid (GHB) and 5-fluorouracil (5-FU), inhibited the angiogenesis induced by murine renal cell carcinoma." | 3.71 | gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor. ( Aoyagi, K; Basaki, Y; Chikahisa, L; Hashimoto, A; Miyadera, K; Okabe, S; Wierzba, K; Yamada, Y; Yonekura, K, 2001) |
| "We report a case of acute myelogenous leukemia (AML) with MLL (myeloid-lymphoid leukemia or mixed-lineage leukemia) gene rearrangement after exposure to tegafur/uracil." | 3.71 | MLL gene rearrangement in acute myelogenous leukemia after exposure to tegafur/uracil. ( Fukushima, T; Kida, H; Noto, Y; Yoshio, N, 2002) |
| "The relationship between augmentation of cytotoxic activity of 5-fluorouracil (FUra) by l-leucovorin (l-LV) and combination schedule was investigated using human colon adenocarcinoma KM 20 C cell line." | 3.69 | [Augmentation of chemotherapeutic efficaciousness of UFT by oral l-leucovorin--l-leucovorin factors enhancing cytotoxic activity of 5-fluorouracil]. ( Okabe, H; Takeda, S; Toko, T; Unemi, N; Yuasa, C, 1995) |
| " In a previous study, the authors demonstrated that the combination of uracil and tegafur (UFT) with leucovorin (LV) was active and well tolerated in patients with advanced colorectal carcinoma (ACC)." | 3.69 | Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group. ( Colmenarejo, A; de Castro, J; de la Gándara, I; Espinosa, E; Espinosa, J; Feliu, J; Fernández, Y; García Girón, C; González Barón, M; Jalón, JI, 1997) |
| " Following our former report in which the combination effects of mitomycin C (MMC) and 5'-deoxy-5-fluorouridine (5'-DFUR) were clarified, combined applications of 4 drugs, vindesine (VDS), methotrexate (MTX), cisplatin (CDDP) and 5'-DFUR against 3 lines of human breast cancer (H-62, H-31, H-71), and one line each of gastric cancer (H-55) and colon cancer (H-110) xenografted into nude mice were evaluated in comparison with CAF (cyclophosphamide, adriamycin and 5-FU) therapy which is commonly used for breast cancer." | 3.67 | [Combination chemotherapy with 3 or 4 drugs on human breast and gastrointestinal cancer xenografts in nude mice (II)]. ( Fujita, F; Fujita, M; Inaba, H; Sakamoto, Y; Shimozuma, K; Taguchi, T, 1987) |
| "A total of 65 patients with advanced colorectal or breast cancer were given oral tegafur in the phase I study." | 3.66 | Phase I-II studies of oral tegafur (ftorafur). ( Ansfield, FJ; Kallas, GJ; Singson, JP, 1983) |
| "Patients aged 20-80 with stage II/III rectal cancer undergoing curative surgery without preoperative therapy were randomly assigned to receive UFT (500-600 mg/day on days 1-5, followed by 2 days rest) or S-1 (80-120 mg/day on days 1-28, followed by 14 days rest) for 1 year." | 2.82 | A randomized phase III trial comparing S-1 versus UFT as adjuvant chemotherapy for stage II/III rectal cancer (JFMC35-C1: ACTS-RC). ( Baba, H; Emi, Y; Hamada, C; Ikejiri, K; Kakeji, Y; Kotake, M; Maeda, K; Maehara, Y; Matsuda, C; Matsuda, H; Munemoto, Y; Murata, A; Oki, E; Saji, S; Sasaki, K; Suenaga, T; Yoshida, K, 2016) |
| " In both arms, S-1 dosing (oral) will be based on body surface area (80 mg/day for body surface area<1." | 2.80 | Randomized phase II study of S-1 dosing schedule for resected colorectal cancer. ( Doki, Y; Hasegawa, J; Hata, T; Ikeda, M; Ikenaga, M; Kato, T; Matsuda, C; Mizushima, T; Mori, M; Murata, K; Nakata, K; Nezu, R; Nishimura, J; Ohue, M; Satoh, T; Sekimoto, M; Shingai, T; Takemasa, I; Uemura, M; Yamamoto, H, 2015) |
| " The overall incidence of adverse events (AEs) was 75." | 2.79 | Safety analysis of two different regimens of uracil-tegafur plus leucovorin as adjuvant chemotherapy for high-risk stage II and III colon cancer in a phase III trial comparing 6 with 18 months of treatment: JFMC33-0502 trial. ( Baba, H; Hamada, C; Kakeji, Y; Katsumata, K; Koda, K; Kodaira, S; Kondo, K; Matsuoka, J; Morita, T; Nishimura, G; Sadahiro, S; Saji, S; Sasaki, K; Sato, S; Tsuchiya, T; Usuki, H; Yamaguchi, Y, 2014) |
| " The overall incidence of adverse events (AEs) were 80% in S-1 and 74% in UFT/LV." | 2.77 | Safety of UFT/LV and S-1 as adjuvant therapy for stage III colon cancer in phase III trial: ACTS-CC trial. ( Boku, N; Endo, T; Ikejiri, K; Kameoka, S; Kinugasa, Y; Kotake, K; Matsubara, Y; Mochizuki, H; Mochizuki, I; Nakamoto, Y; Shinozaki, H; Sugihara, K; Takagane, A; Takahashi, K; Takahashi, Y; Takii, Y; Takiuchi, H; Tomita, N; Watanabe, M; Watanabe, T, 2012) |
| "SACURA trial is a multicenter randomized phase III study which aims to evaluate the superiority of 1-year adjuvant treatment with UFT to observation without any adjuvant treatment after surgery for stage II colon cancer in a large population, and to identify "high-risk factors of recurrence/death" in stage II colon cancer and predictors of efficacy and adverse events of the chemotherapy." | 2.77 | Study protocol of the SACURA trial: a randomized phase III trial of efficacy and safety of UFT as adjuvant chemotherapy for stage II colon cancer. ( Ishiguro, M; Ishikawa, T; Kanemitsu, Y; Kotake, K; Matsui, S; Mochizuki, H; Shimada, Y; Sugihara, K; Takahashi, K; Teramukai, S; Tomita, N; Ueno, H; Uetake, H; Watanabe, M, 2012) |
| " Major adverse effects were hematological toxicities, gastrointestinal disturbance, neurosensory toxicity." | 2.76 | [Efficacy and side effects of combination therapy of oxaliplatin and S-1 for colorectal cancer]. ( Jin, ZM; Zhu, QC, 2011) |
| "Of the total patients, 47% had stage II colon cancer, and 53% had stage III colon cancer." | 2.72 | Oral uracil and tegafur plus leucovorin compared with intravenous fluorouracil and leucovorin in stage II and III carcinoma of the colon: results from National Surgical Adjuvant Breast and Bowel Project Protocol C-06. ( Colangelo, LH; Colman, LK; Giguere, JK; Jacobs, AD; Lembersky, BC; Marshall, ME; O'Connell, MJ; Petrelli, NJ; Seay, TE; Smith, RE; Soran, A; Wieand, HS; Wolmark, N; Yothers, G, 2006) |
| "Colon cancer was located in the rectosigmoid in 46." | 2.72 | Diverticular disease in patients with colon cancer: subgroup analysis of national surgical adjuvant breast and bowel project protocol C-06. ( Harlak, A; Lembersky, BC; Nesbitt, L; O'Connell, MJ; Soran, A; Wienad, HS; Wilson, JW, 2006) |
| "A total of 760 patients with colon cancer and 669 patients with rectal cancer were entered into this randomized clinical trial (RCT)." | 2.71 | Randomized controlled trial of the efficacy of adjuvant immunochemotherapy and adjuvant chemotherapy for colorectal cancer, using different combinations of the intracutaneous streptococcal preparation OK-432 and the oral pyrimidines 1-hexylcarbamoyl-5-flu ( Hojyo, K; Isomoto, H; Kato, T; Kodaira, S; Kunii, Y; Kunitomo, K; Niimoto, M; Nishida, O; Ohashi, Y; Takahashi, T; Tominaga, T; Watanabe, M; Yasutomi, M, 2004) |
| " cis-Diaminedichloroplatinum (cisplatin) has been reported to immunomodulate, especially when used in low dose in combination with 5-Fluorouracil (5-FU)." | 2.70 | Immunomodulatory effects of low dose cis-Diaminedichloroplatinum (cisplatin) combined with UFT and PSK in patients with advanced colorectal cancer. ( Ando, K; Fukuzawa, M; Kanou, H; Kimura, T; Nagata, Y; Nezu, T; Shibata, M; Takekawa, M, 2002) |
| " Based on the feasibility and adverse reactions, the dosage of UFT should be set according to the body surface area at 375-425 mg/m2/day." | 2.69 | [Optimal dosage of UFT in a weekday-on/weekend-off schedule as a postoperative adjuvant chemotherapy for colorectal cancer]. ( Fukushima, T; Hiki, Y; Kumada, K; Makuuchi, H; Mitomi, T; Nagasaki, H; Nishiyama, K; Ohki, S; Otani, Y; Sadahiro, S; Shimada, H; Takahashi, T; Takemiya, S; Tsukikawa, S; Yamaguchi, S; Yamamura, T, 2000) |
| "For the local recurrence of rectal cancer, it was observed in Dukes C and cases of relative curative resection." | 2.68 | [Cooperative study of surgical adjuvant chemotherapy for colorectal cancer. Cooperative Study Group of Surgical Adjuvant Chemotherapy for Colorectal Cancer in Japan]. ( Kikuchi, K; Kunii, Y, 1995) |
| "In collaboration with 428 institutions nation-wide, comparative studies on the optimal daily dosage of UFT were carried out for non-curative resection cases of colorectal cancer for two years from January 1984 to December 1985." | 2.67 | [Cooperative Study of Surgical Adjuvant Chemotherapy for Colorectal Cancer (fourth report): five-year results after surgery]. ( Abe, O; Hattori, T; Inokuchi, K; Kikuchi, K; Komi, N; Kondo, T; Maehara, Y; Sugimachi, K; Taguchi, T; Uchino, J, 1993) |
| "Five-year survival was 82." | 2.67 | [Clinical effect of postoperative adjuvant chemotherapy for advanced colorectal cancer--comparisons of between tegafur (FT) and UFT]. ( Gotoda, H; Kinami, Y; Miyazaki, I; Saito, H; Takashima, S; Tomita, F; Yamaguchi, A, 1991) |
| "Patients (1,256 with colon cancer, 1,221 with rectal cancer) were divided into the treatment group (group A) and the control group (surgical resection only, group B)." | 2.66 | [Cooperative study of surgical adjuvant chemotherapy of colorectal carcinoma (second study): a preliminary report. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan]. ( Abe, O; Hattori, T; Inokuchi, K; Kikuchi, K; Kodaira, S; Komi, N; Kondo, T; Ogawa, N; Taguchi, T; Uchino, J, 1989) |
| "The group of research for colorectal cancer treatments-Kajitani-group (chief T." | 2.66 | [Adjuvant chemotherapy of colorectal cancer--results of prospective randomized trials]. ( Hojo, K; Kajitani, T, 1986) |
| "In the colon cancer patients, 5-year survival rates were 88." | 2.66 | [Clinical effect of postoperative adjuvant immunochemotherapy with the FT-207 suppository and PSK in colorectal cancer patients. Colorectal Cancer Chemotherapy Group in Hokuriku]. ( Kinami, Y; Miyazaki, I; Takashima, S, 1988) |
| "The rate of local recidivation in colon cancer resected curatively was higher in ACNU + FT group than in FT only group (p less than 0." | 2.66 | [A cooperative study of surgical adjuvant chemotherapy of colorectal cancer (second report): 3-year survival rate. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan]. ( Abe, O; Hattori, T; Inokuchi, K; Kasai, Y; Kikuchi, K; Komi, N; Kondo, T; Niimoto, M; Ogawa, N; Taguchi, T, 1988) |
| "Oral tegafur and I." | 2.65 | A comparative study of oral tegafur and intravenous 5-fluorouracil in patients with metastatic colorectal cancer. ( Bedikian, AY; Bodey, GP; Karlin, D; Korinek, J; Stroehlein, J, 1983) |
| " The optimal dosage was considered to be between 17 mg/kg and 24 mg/kg." | 2.65 | [Joint clinical Phase II study of SF-SP]. ( Hanatani, Y; Sato, H; Sato, T, 1984) |
| "With rectal cancer, 5-year survival was 57." | 2.65 | [Evaluation of preoperative administration of N1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) suppository in surgical adjuvant chemotherapy for large bowel cancer]. ( Fujita, H; Kosaka, T; Miyazaki, I; Takashima, S; Ueno, K, 1984) |
| "After the operation, he developed disseminated intravascular coagulation(DIC)and severe anemia." | 2.50 | [A case of disseminated carcinomatosis of the bone marrow with disseminated intravascular coagulation caused by advanced colon cancer successfully treated with SOX/bevacizumab]. ( Endo, Y; Inoue, M; Kakimoto, Y; Kato, Y; Kimura, T; Matsuda, Y; Matsuoka, N; Murakami, O; Sasakabe, H; Suzuki, H; Toyoda, A; Ushimaru, Y, 2014) |
| "UFT (tegafur and uracil) is an oral anticancer drug that has been developed in Japan." | 2.44 | UFT (tegafur and uracil) as postoperative adjuvant chemotherapy for solid tumors (carcinoma of the lung, stomach, colon/rectum, and breast): clinical evidence, mechanism of action, and future direction. ( Tanaka, F, 2007) |
| "In stage II colon cancer, treatment strategies are more debated." | 2.43 | [Adjuvant treatment of colorectal cancer]. ( Afchain, P; André, T; de Gramont, A; Segura, C, 2006) |
| "Adjuvant therapy of colorectal cancer with oral fluorinated pyrimidines is attractive because of its ease of administration and good tolerability." | 2.42 | Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials. ( Burzykowski, T; Buyse, M; Hamada, C; Ohashi, Y; Piedbois, P; Sakamoto, J, 2004) |
| "Fluorouracil has been used for a long time, remission rates reported range from 0% to 80%." | 2.36 | [Chemotherapy of gastrointestinal tumors (review of the literature)]. ( Mayr, AC, 1978) |
| "It revealed a peritoneal recurrence in the pouch of Douglas." | 1.72 | [A Case Report for Peritoneal Recurrences by Laparoscopic Surgery after Colorectal Cancer Resection]. ( Arakawa, A; Ii, Y; Irie, T; Kawaguchi, M; Kawai, M; Kobari, A; Kojima, Y; Momose, H; Sakamoto, K; Sugimoto, K; Terao, Y; Tomiki, Y; Tsukamoto, R, 2022) |
| " During long-term administration of S-1, some mice had loose stools and an increase in apoptotic bodies was observed in the ileal crypts." | 1.46 | Lentinan diminishes apoptotic bodies in the ileal crypts associated with S-1 administration. ( Suga, Y; Takehana, K, 2017) |
| "Records of patients with stage III colon cancer who underwent curative surgery and adjuvant chemotherapy from April 2007 and September 2014 were retrospectively reviewed." | 1.46 | Oncologic Outcomes of Oral Adjuvant Chemotherapy Regimens in Stage III Colon Cancer: Tegafur-Uracil Plus Leucovorin Versus Capecitabine. ( Hara, K; Ishii, T; Kondo, H; Shimizu, H; Suzuki, A; Takemoto, K; Tashiro, J; Yamaguchi, S, 2017) |
| "The mean recurrence-free survival was 13." | 1.43 | [Adjuvant Systemic Chemotherapy with S-1/Oxaliplatin or mFOLFOX6 after Curative Resection of Distant Metastases in Patients with Colorectal Cancer]. ( Amada, E; Baba, S; Kameyama, N; Mitsuhashi, H; Miyata, R; Tomita, M, 2016) |
| "288 patients presenting with stage III colon cancer and undergoing adjuvant therapies after curative surgery for more than 3-month were enrolled between January 2006 and December 2011." | 1.42 | Stage III Colon Cancer: The Individualized Strategy of Adjuvant Chemotherapy for Aged Under and Over 70. ( Chang, PY; Chen, JH; Chen, YG; Ho, CL; Lu, CS; Wu, YY, 2015) |
| "Metastatic recurrence occurred on the transverse colon, for which she underwent transverse colectomy 2." | 1.42 | [A Successful Case of Treatment of Colonic Metastasis and Peritoneal Recurrence of Type 4 Gastric Cancer by Using Colectomy and Chemotherapy]. ( Fujii, Y; Fujita, H; Fujita, J; Funaki, H; Kaida, D; Kinami, S; Kosaka, T; Miura, S; Morioka, E; Nakano, Y; Noguchi, M; Ohonishi, T; Ohono, Y; Sakata, N; Tomita, Y; Ueda, N, 2015) |
| "We report a case of ascending colon cancer with right extra iliac lymph node metastases." | 1.42 | [A Case of Ascending Colon Cancer with Extra Iliac Lymph Node Metastases]. ( Amaya, K; Kaji, M; Kawahara, Y; Maeda, K; Shimizu, K; Terada, I; Terai, S; Watanabe, T; Yamamoto, S, 2015) |
| "A 55-year-old man suffering from gastric cancer associated with metastases to the lymph node, gallbladder, and liver was administered chemotherapy with S-1 and cisplatin." | 1.40 | [A case of metastatic colon carcinoma following curative resection for advanced gastric cancer associated with metastases to the liver and gallbladder]. ( Akiyama, Y; Hasuike, Y; Higuchi, I; Miyamoto, M; Tanigawa, T; Yamamoto, M, 2014) |
| "She was diagnosed as colon cancer with hepatic metastasis." | 1.39 | [A case of metastatic colon cancer effectively treated by XELOX and IRIS]. ( Fujiyama, Y; Kaneko, H; Kikuchi, M; Kinoshita, S; Nishizawa, T; Sakuno, T; Suzuki, H; Takahashi, M, 2013) |
| "Between 2002 and 2011, 333 Stage III colon cancer patients had surgery performed in our institute, and we studied 25 of them on our chemotherapy regimen." | 1.39 | [A retrospective study of UFT and oral leucovorin combination adjuvant chemotherapy for patients over 76 years old with stage III colon cancer]. ( Hanaoka, Y; Hashimoto, M; Kuroyanagi, H; Matoba, S; Moriyama, J; Toda, S; Tomizawa, K; Udagawa, H; Watanabe, G, 2013) |
| "We recently proposed an S-1 combined with oxaliplatin (SOXL) regimen, a combination treatment consisting of oral metronomic S-1 dosing and intravenous administration of oxaliplatin (l-OHP) containing PEGylated liposomes, which showed potent antitumor activity in vivo." | 1.39 | Abrogation of the accelerated blood clearance phenomenon by SOXL regimen: promise for clinical application. ( Abu Lila, AS; Ishida, T; Kiwada, H; Nagao, A, 2013) |
| "Between 2003 and 2009, 273 stage III colon cancer patients underwent surgery in our institute, and we studied 156 of them." | 1.38 | [A retrospective study of UFT and oral leucovorin plus PSK combination adjuvant chemotherapy in patients with stage III colon cancer]. ( Hanaoka, Y; Hashimoto, M; Kumamoto, T; Kuroyanagi, H; Matoba, S; Moriyama, J; Sawada, T; Toda, S; Tomizawa, K; Udagawa, H; Watanabe, G, 2012) |
| "A 61-year-old man on hemodialysis due to chronic renal failure caused by diabetes mellitus was diagnosed as having ascending colon cancer with multiple liver metastases." | 1.38 | [A case of stage IV colon cancer effectively treated with tegafur uracil/calcium folinate in a patient on hemodialysis]. ( Kobayashi, M; Maeda, H; Okamoto, K; Takeshita, A, 2012) |
| " When chemotherapy with S-1 or UFT/LV started from the micrometastasis stage, not the advanced macroscopic metastasis stage, anti-LNM efficacy of S-1 was significantly higher than that of UFT/LV at the dosage in which antitumor activity of the two drugs against primary subcutaneous tumor was comparable." | 1.36 | Characterization of a novel lymph node metastasis model from human colonic cancer and its preclinical use for comparison of anti-metastatic efficacy between oral S-1 and UFT/ LV. ( Hirai, T; Ito, Y; Kato, T; Kodera, Y; Nakanishi, H; Nakao, A, 2010) |
| "A 78-year-old male with sigmoid colon cancer underwent sigmoidectomy." | 1.35 | [A patient in whom oral UFT/Leucovorin therapy proved markedly effective for lung metastasis after surgery for colon cancer]. ( Abe, K; Itoh, K; Kamiizumi, Y; Kawamura, N; Nakajima, Y; Okamura, M; Yokoyama, R, 2008) |
| " We treated the patient with S-1 combined with CPT-11." | 1.35 | [Three cases with liver metastasis from gastric or colon cancer successfully treated with S-1 combined with CPT- 11]. ( Ishii, Y; Mado, K; Manmoto, J; Masuda, H; Mazaki, T; Okame, H; Suzuki, K; Takayama, T, 2008) |
| "Goblet cell carcinoid of the appendix is a rare neoplasm and clinically tends to take a malignant course." | 1.35 | [A case of peritonitis carcinomatosa from goblet cell carcinoid of the appendix treated by intraperitoneal paclitaxel and systemic S-1 chemotherapy]. ( Fujimoto, H; Harada, E; Horiuchi, N; Iwasaka, N; Kashima, M; Kimura, S; Masuda, K; Matsushita, T; Nakamura, S; Oshima, Y; Shichijo, K; Shinomiya, S; Takeichi, T; Tamaki, Y; Yoshida, S, 2008) |
| "Thirty-three patients with rectal cancer underwent preoperative CRT." | 1.35 | Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy. ( Ioue, Y; Kusunoki, M; Miki, C; Okugawa, Y; Saigusa, S; Tanaka, K; Toiyama, Y; Yokoe, T, 2009) |
| "For patients with T3N0M0 colon cancer without known risk factors, the necessity of chemotherapy has no definite consensus." | 1.35 | The necessity of chemotherapy in T3N0M0 colon cancer without risk factors. ( Cho, YB; Chun, HK; Kim, HC; Lee, WY; Yun, HR; Yun, SH, 2009) |
| "Lymph node metastasis was not found by CT scan 20 months after beginning chemotherapy." | 1.35 | [A case of effective treatment with UFT/LV chemotherapy for para-aortic lymph node metastasis from colonic cancer 8 years after colectomy]. ( Kimura, H; Takamura, H; Watanabe, K, 2009) |
| "A 45-year-old male patient with right colonic cancer, of which clinical finding was SIM1 (No." | 1.35 | [A case of advanced right colonic cancer successfully treated by surgery and post operative chemotherapy]. ( Inoue, S; Nasu, K; Noda, K; Umekita, N, 2009) |
| "An 82-year-old female with unresectable colon cancer accompanied by multiple lung metastasis was treated with S-1." | 1.35 | [An elderly case of recurrent colon cancer responding to weekly S-1 chemotherapy leading to partial response]. ( Arita, A; Fujimoto, M; Mochizuki, K; Sakai, Y, 2008) |
| "Fifty-one patients with postoperative colon cancer (mean 61." | 1.33 | Effects of oral 5-fluorouracil drugs on hepatic fat content in patients with colon cancer. ( Hayakawa, K; Miyake, K; Morimoto, T; Mukaihara, S; Nishino, M, 2005) |
| "A 54-year-old woman who had ascending colon cancer with multiple liver and lung metastases underwent rt." | 1.33 | [A case of colon cancer with multiple liver, lung and bone metastases successfully treated with combined weekly high-dose 5-FU (WHF) chemotherapy with UFT and CPT-11]. ( Fujii, Y; Kobayashi, T; Kuga, T; Matsuoka, T; Morikage, N; Nakayama, T, 2005) |
| "By a diagnosis of descending colon cancer, descending colon ablative operation and D1 lymph node dissection were performed on April 22, 2004." | 1.33 | [A case of peritoneal dissemination disappeared by CPT-11 + TS-1 combination chemotherapy]. ( Fujishima, M; Fukunaga, M; Furukawa, H; Imamura, H; Kawasaki, T; Kishimoto, T; Kondo, M; Masutani, S; Nakayama, T; Ooshiro, R; Takemoto, H; Tanaka, J; Tatsuta, M; Yamamoto, K, 2005) |
| "The patient, who had unresectable colon cancer metastases to the liver and lung, was referred to us for chemotherapy from an affiliated hospital; he had no cardiac history." | 1.33 | 5-Fluorouracil cardiotoxicity induced by alpha-fluoro-beta-alanine. ( Hatakeyama, K; Muneoka, K; Shirai, Y; Wakai, T; Yokoyama, N, 2005) |
| "Among these patients, 8 developed hyperbilirubinemia." | 1.33 | [Efficacy of the combined use of taurine for hyperbilirubinemia caused by UFT therapy after surgery for colonic cancer]. ( Fujii, K; Iizuka, R; Ikawa, O; Izumi, H; Kakihara, N; Katoh, Y; Matsumura, H; Miyata, K; Ohgaki, M; Shimomura, K; Shimotsuma, M; Tkenaka, A, 2006) |
| "Two metastatic colonic cancer patients were successfully treated by the combination therapy of UFT plus oral Leucovorin (UFT/LV)." | 1.33 | [Two metastatic colonic cancer patients successfully treated by combination therapy of tegafur/uracil (UFT) and oral Leucovorin]. ( Ando, T; Goto, H; Ina, K; Inagaki, J; Ito, A; Kataoka, T; Kato, H; Nagao, S; Niwa, Y; Ohkita, T, 2006) |
| "A 54-year-old man with colon cancer underwent hemicolectomy." | 1.32 | Therapy-related erythroleukemia caused by the administration of UFT and mitomycin C in a patient with colon cancer. ( Miyazaki, M; Nakamori, Y; Shinohara, K; Taguchi, A; Tominaga, T, 2003) |
| " Pharmacokinetic modulating chemotherapy (PMC) was performed after the operation." | 1.32 | [A case of multiple liver metastases from colon cancer successfully treated with pharmacokinetic modulating chemotherapy]. ( Futamura, N; Matsutomo, M; Sakamoto, K; Tateyama, K; Yasumura, M, 2003) |
| " He was treated with pharmacokinetic modulating chemotherapy (PMC) and low-dose CPT-11." | 1.32 | [A case of highly advanced ascending colon cancer with multiple bone and liver metastases and pleuritis carcinomatosa treated with pharmacokinetic modulating chemotherapy and low-dose CPT-11]. ( Aihara, T; Fukuhara, A; Kouno, T; Murayama, M; Nakagawa, K; Nakamura, E; Niida, M; Nishimoto, Y; Nozaki, H; Syouda, S; Watanabe, Y; Yagyu, T; Yasuoka, H, 2004) |
| "Gastrointestinal endoscopy showed esophageal cancer invading the gastric fundus." | 1.32 | Esophageal cancer with colonic metastasis successfully treated by chemoradiotherapy followed by chemotherapy with S-1 and cisplatin. ( Doi, R; Indo, T; Iwase, H; Kaida, S; Kato, E; Nakarai, K; Okeya, M; Shimada, M; Tsuzuki, T, 2004) |
| "Diarrhea was the major adverse effect of UFT/LV that made patients reduce dosage." | 1.31 | Oral uracil/ftorafur (UFT) plus leucovorin as first-line chemotherapy and salvage therapy with weekly high-dose 5-fluorouracil/leucovorin for the treatment of metastatic colorectal cancer. ( Chen, JS; Hsu, KC; Tang, R; Wang, JY; Yang, TS, 2002) |
| " Administration of modified pharmacokinetic modulating chemotherapy (PMC) using Leucovorin (intravenous infusion of 5-FU, 600 mg/m2/24 hours; oral administration of UFT, Taiho Pharmaceutical Co." | 1.31 | [A case of multiple liver metastases from colon cancer successfully treated with modified pharmacokinetic modulating chemotherapy using Leucovorin]. ( Hatada, T; Inoue, Y; Kobayashi, M; Kusunoki, M; Miki, C; Ojima, E, 2002) |
| "However, the sensitivity to the micrometastases was high." | 1.31 | Experimental postoperative adjuvant chemotherapy by UFT using primary tumor amputation model. ( Fujioka, A; Fukushima, M; Nakano, K; Okabe, H; Saito, H; Sato, K; Takechi, T; Takeda, S; Uchida, J; Unemi, N, 2000) |
| "We encountered a case of unresectable colon cancer that disappeared following pharmacokinetic modulating chemotherapy (PMC)." | 1.31 | [A case report of unresectable colon cancer that disappeared following pharmacokinetic modulation chemotherapy (PMC)]. ( Asahara, T; Nakahara, H; Nakahara, M; Okajima, M; Yano, M, 2000) |
| "For cases of liver metastasis from colon cancer that are non-resectable due to multiple liver metastases, other organ metastases (lung, bone, brain etc." | 1.31 | [Three cases of liver metastasis of colon cancer responding to systemic combination chemotherapy utilizing CPT-11]. ( Kobayashi, A; Yamaguchi, M, 2000) |
| "Tegafur is a prodrug that is converted to 5-fluorouracil (5-FU) and has been reported to be less toxic and to have a higher therapeutic index." | 1.31 | Phase II study of oral tegafur-uracil and folinic acid as first-line therapy for metastatic colorectal cancer: Taiwan experience. ( Chen, PM; Chiou, TJ; Fan, FS; Hsieh, RK; Hsu, TC; Jiang, JK; Lin, JK; Lin, TC; Liu, JH; Wang, HS; Wang, WS; Yang, SH; Yen, CC, 2000) |
| "A total of 18 patients (13: colon cancer, 5: gastric cancer) with multiple liver metastases (H3) underwent hepatic arterial infusion chemotherapy (HAI) using an implanted arterial port with portable syringe pumps in our outpatient clinic." | 1.31 | [Outcomes of home anti-cancer chemotherapy--estimation of hepatic arterial infusion chemotherapy for patients with multiple liver metastases]. ( Fukunaga, M; Goda, F; Maeba, T; Maeta, H; Mihara, T; Mori, S; Ohkawa, M; Okada, H; Okano, K; Senda, S; Uchida, Y; Usuki, H; Wakabayashi, H, 2000) |
| "A case of haemolytic anaemia in a patient under treatment with UFT for metastatic colon cancer is reported." | 1.31 | UFT-induced haemolytic anaemia. ( Español, I; Fernández Ortega, A; Navarro Garcia, M; Zurita Saavedra, AJ, 2001) |
| "Human colon cancer cells (KM12SM) were injected into the cecal wall of the nude rats." | 1.31 | [Relationship between the anti-metastatic effect of UFT and in vitro chemosensitivity to 5-FU in metastatic tumors from orthotopic implanted colon cancer in nude rats]. ( Akagi, Y; Kobayashi, H; Matono, K; Miyagi, Y; Nakagawa, M; Nozoe, Y; Ogata, Y; Sasatomi, T; Shirouzu, K, 2001) |
| "The therapeutic effect of S-1 on human colon cancer xenografts (TK-13) with high metastatic potential to the liver was evaluated." | 1.30 | Therapeutic effect of 1 M tegafur-0.4 M 5-chloro-2,4-dihydroxypyridine-1 M potassium oxonate (S-1) on liver metastasis of xenotransplanted human colon carcinoma. ( Baba, M; Kamiya, K; Kanai, T; Konno, H; Matsumoto, K; Nakamura, S; Tanaka, T, 1999) |
| "A 47-year-old man with ascending colon cancer with multiple liver metastases and bone metastasis (VII thoracic vertebra) showed a remarkable response to the combination therapy of tegafur and cisplatin." | 1.29 | [A case of remarkable response of colon cancer with multiple liver and bone metastasis treated with tegafur and cisplatin]. ( Arima, S; Futami, K; Hara, F; Harada, Y; Inada, S; Kotoh, T; Nishida, T; Tateishi, S; Yamasaki, K, 1995) |
| "Thirty-nine patients with gastric or colonic cancer were given preoperative chemotherapy with UFT (an admixture of tegafur and uracil)." | 1.29 | Effects of preoperative chemotherapy on DNA ploidy patterns, cell cycle, and histological findings in gastric and colonic cancer patients. ( Arizono, S; Kajiura, N; Konishi, T; Kubota, K; Makuuchi, M; Nakao, K; Oka, T; Teruya, M; Tsushima, H, 1994) |
| "Effects of 5-fluorouracil (5-FU) and UFT on an experimental liver metastasis model were compared at equi-effective dosage levels against subcutaneous tumor of mouse colon 26." | 1.29 | Effect of 5-fluorouracil and UFT on experimental liver metastasis model of colorectal cancer using mouse colon 26 cells. ( Kosaki, G; Kurihara, M; Tominaga, T; Yoshida, Y, 1993) |
| "To evaluate the effect of the oral fluoropyrimidines, tegafur and uracil (UFT) and 5-fluorouracil (5-FU), a pharmacodynamic analysis was conducted using a nude mouse system and patients." | 1.29 | A pharmacodynamic and pharmacokinetic study of fluoropyrimidines in a nude mouse system and in postoperative patients with gastric cancer. ( Hishinuma, S; Ikeda, T; Inada, T; Kotake, K; Koyama, Y; Kubota, T; Ogata, Y; Ozawa, I; Shimizu, H, 1993) |
| "Tegafur or UFT was administrated orally to patients with gastric or colorectal cancers after surgery for at least a year." | 1.29 | [Evaluation of long-term administration of oral anti-cancer agent]. ( Sakakibara, N; Watanabe, H, 1993) |
| "injection against mouse colon cancer, colon 26." | 1.28 | [Antitumor activity of T-506, a novel synthetic FUDR derivative, on murine colon cancer and its hepatic metastasis]. ( Fujimaki, M; Kurokawa, M; Kuroki, Y; Ochiai, H; Okamoto, M; Tazawa, K; Yamashita, I, 1991) |
| "5-FU concentration in liver cancer lesion was 0." | 1.28 | [Tissue UFT distribution and histological changes following UFT administration in metastatic liver cancer cases]. ( Amemiya, A; Emoto, T; Fujii, M; Han, N; Itou, A; Iwasaki, T; Tsujimura, T; Yoshikawa, K, 1990) |
| "Thirty four patients with advanced gastric cancer (GC), colon cancer (CC) biliary tract cancer (BC) and pancreatic cancer (PC) were treated with a combined chemotherapy of UFT with ADM (UFT-A), or UFT with ADM and CDDP (UFT-AC)." | 1.28 | [Combination chemotherapy of UFT with adriamycin (ADM) and cisplatin (CDDP) for advanced gastrointestinal cancer]. ( Koda, K; Kure, T; Matsunaga, T; Miyazaki, E; Morii, K; Morita, K; Nakajima, K; Nakazawa, O; Terada, S; Tsuji, Y, 1990) |
| "In 14 gastric cancer and 15 colonic cancer cases, to which UFT 400 mg/day and OK-432 2KE 2/W were administered orally and intra-muscularly for 2 weeks preoperatively until surgical treatment, intratumor 5-fluorouracil (5-FU) concentration was measured and compared with that of patients who given UFT 400 mg/day orally for 2 weeks (15 gastric cancer and 15 colonic cancer cases)." | 1.28 | [Influence of OK-432 on intratumor 5-fluorouracil concentration in cases given UFT]. ( Hosoi, H; Kitagawa, M; Sinmyo, K; Susaki, H; Suwa, H; Yamaguchi, K, 1989) |
| "Tegafur (FT) is a masked compound of 5-fluorouracil (5-FU) and supposed to be activated in the liver." | 1.28 | [Anti-tumor effect of fluoropyrimidines on human tumor cell lines transplanted in nude mice with CCl4-induced liver dysfunction]. ( Imai, S; Nio, Y; Ohgaki, K; Shiraishi, T; Tobe, T, 1989) |
| "One partial remission out of 7 cases of stomach cancer was obtained, and its duration was 40 weeks." | 1.27 | [Clinical trial on the effect of tegafur (SF-SP)]. ( Akazawa, S; Futatsuki, K; Hattori, M; Ishibashi, I; Kanda, Y; Sendai, H; Shimada, S, 1984) |
| "CR was observed in one case of breast cancer, and PR in 29 cases." | 1.27 | [Cooperative phase II study of spansule tegafur (SF-SP)]. ( Taguchi, T, 1984) |
| "5 degrees C, 3 X 60 min) alone and in combination with polychemotherapy (BCNU) and Ftorafur) was used for the treatment of AMMN-(N-nitrosoacetoxymethyl-methylamine) induced autochthonous colonic carcinomas in Sprague-Dawley rats." | 1.27 | [Effect of local moderate hyperthermia in combination with N-nitroso-1,3-bis-(2-chloroethyl)urea (BCNU) and 5-fluoro-(tetrahydro-2-furyl)uracil (ftorafur) on induced autochthonous colonic cancers in the rat. 3: Polychemotherapy in combination with hyperth ( Biwer, E; Habs, M; Lorenz, M; Schmähl, D, 1984) |
| "Preoperative total doses of UFT for gastric cancer were 3." | 1.27 | [Effects of preoperative administration of UFT in gastrointestinal cancer]. ( Kagaya, H; Matsuoka, S; Miyata, S; Nagabuchi, E; Sato, Y; Uchino, J; Une, Y; Yakura, Y, 1986) |
| " In these 5 cases the daily dosage was 800 mg, and the median duration of PR was 51 days." | 1.27 | [Study of chemotherapy in the field of internal medicine--clinical experience with SF-SP]. ( Fujisawa, T; Imamura, Y; Irie, K; Mizogami, H; Nakamura, T; Nishimura, S; Sawada, Y; Yasutake, K; Yoshida, M; Yoshimura, Y, 1986) |
| " However, increase in tegafur dosage volume did not correlate with 5-FU levels." | 1.27 | [5-FU concentration in the blood and tissue of patients with gastric and colorectal cancer after administration of UFT or tegafur]. ( Arima, S; Futami, K; Kinashi, M; Shigeta, M; Shimura, H, 1986) |
| "A chemosensitivity test for UFT and FT-207, which are used in long-term administration clinically, was investigated for prediction of clinical response." | 1.27 | [In vivo chemosensitivity test for UFT and FT-207. I--Subrenal capsule assay]. ( Hattori, T; Hirabayashi, N; Niimi, K; Niimoto, M; Nishiyama, M; Nosoh, Y; Tohge, T; Yamaguchi, M, 1987) |
| " UFT inhibited significantly the tumor growth of CH-I established from colon cancer in which the prolongation of life span has been obtained by clinical long-term administration of UFT." | 1.27 | [In vivo chemosensitivity test for UFT and FT-207. II. Chemosensitivity test on human tumor xenografts transplanted in nude mice]. ( Hattori, T; Hirabayashi, N; Niimi, K; Niimoto, M; Nishiyama, M; Nosoh, Y; Toge, T; Wang, DC; Yamaguchi, M, 1987) |
| "Five-fluorouracil was measured by GC-MF method and FT-207 was also done by HPLC method." | 1.27 | [The effect of tegafur suppository and glutathione in patients with gastric and colonic cancer with special reference to the histopathological anticancer effect]. ( Fukuzumi, N; Ikeda, Y; Kaga, F; Kitajima, M; Kiuchi, T; Okada, N, 1987) |
| "The sensitivity of human colorectal cancer to 5-fluorouracil (5-FU) and its derivatives: 1-(tetrahydro-2-furyl)-5-FU (tegafur) and 1-hexylcarbamoyl-5-FU (HCFU) was determined by in vitro succinate dehydrogenase inhibition (SDI) test and in vivo subrenal capsule (SRC) assay." | 1.27 | [Human colorectal carcinoma is more sensitive to HCFU than 5-FU and tegafur in in vitro and in vivo drug sensitivity tests]. ( Anai, H; Fukuchi, K; Kusumoto, H; Kusumoto, T; Maehara, Y; Miyamoto, K; Sugimachi, K, 1988) |
| "These were; EH-1 established from esophageal cancer, SH-6 from gastric cancer and CH-3 from colon cancer." | 1.27 | Combined effects of UFT with other anticancer agents using in vivo chemosensitivity tests. ( Hattori, T; Hirabayashi, N; Niimi, K; Niimoto, M; Nishiyama, M; Saeki, T; Takagami, S; Wang, DC; Yamaguchi, M; Yoshinaka, K, 1988) |
| "Fifteen patients with stomach cancer and colorectal cancer were orally administered 600 mg of UFT before operation and the concentration of tegafur, 5-fluorouracil (5-FU) and uracil in the tissues and serum were measured by chemical assay." | 1.27 | [The serum and tissue concentrations of tegafur, 5-fluorouracil and uracil in patients with gastric and colorectal cancers after oral administration of UFT]. ( Kikuchi, K; Kunii, Y; Mori, Y; Nitta, A; Saitou, T; Takahashi, N, 1988) |
| "Five patients with colorectal cancer and unresectable synchronous liver metastases have survived for over five years at this writing." | 1.27 | Long-term survivors of colorectal cancer with unresectable hepatic metastases. ( Fujimoto, S; Higuchi, M; Kitsukawa, Y; Miyazaki, M; Okui, K, 1985) |
| "Tegafur was effective, but levamisole with or without tegafur was not effective against early cancer." | 1.27 | Longer survival and fewer metastases by levamisole and tegafur in 1, 2-dimethylhydrazine-induced murine colonic cancers. ( Aoki, N; Hamada, S; Hirayama, R; Matsumura, J; Mishima, Y; Miyanaga, T; Takagi, Y, 1985) |
| "A retrospective study of 37 colorectal cancer patients with synchronous liver metastases was made." | 1.26 | Comparative efficacy of antitumor treatment for liver metastases from colorectal cancer. ( Fujimoto, S; Kitsukawa, Y; Miyazaki, M; Okui, K, 1981) |
| "Eighty-four previously untreated patients with metastatic adenocarcinoma of the large intestine received intravenous ftorafur at a dosage of 2." | 1.26 | Phase II evaluation of ftorafur in previously untreated colorectal cancer: a Southwest Oncology Group Study. ( Buroker, T; Groppe, C; Guy, G; Heilbrun, L; Hoogstraten, B; McCracken, J; Padilla, F; Quagliana, J; Vaitkevicius, VK, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 78 (25.49) | 18.7374 |
| 1990's | 55 (17.97) | 18.2507 |
| 2000's | 95 (31.05) | 29.6817 |
| 2010's | 68 (22.22) | 24.3611 |
| 2020's | 10 (3.27) | 2.80 |
| Authors | Studies |
|---|---|
| Sadahiro, S | 8 |
| Sakamoto, K | 5 |
| Tsuchiya, T | 4 |
| Takahashi, T | 7 |
| Ohge, H | 2 |
| Sato, T | 5 |
| Kondo, K | 3 |
| Ogata, Y | 3 |
| Baba, H | 6 |
| Itabashi, M | 2 |
| Ikeda, M | 4 |
| Hamada, M | 2 |
| Maeda, K | 4 |
| Masuko, H | 1 |
| Takahashi, K | 7 |
| Sakamoto, J | 2 |
| Kusano, M | 1 |
| Hyodo, I | 2 |
| Taguri, M | 2 |
| Morita, S | 2 |
| Ii, Y | 1 |
| Irie, T | 1 |
| Kobari, A | 1 |
| Kawaguchi, M | 1 |
| Momose, H | 1 |
| Tsukamoto, R | 1 |
| Kawai, M | 3 |
| Sugimoto, K | 2 |
| Kojima, Y | 1 |
| Arakawa, A | 1 |
| Terao, Y | 1 |
| Tomiki, Y | 1 |
| Chen, PH | 2 |
| Jhou, HJ | 1 |
| Chung, CH | 2 |
| Wu, YY | 3 |
| Huang, TC | 2 |
| Lee, CH | 2 |
| Chien, WC | 2 |
| Chen, JH | 4 |
| Ando, K | 2 |
| Emi, Y | 2 |
| Miyanari, N | 1 |
| Tsuji, A | 2 |
| Sakai, K | 2 |
| Sawai, T | 1 |
| Imamura, H | 2 |
| Mori, S | 2 |
| Tokunaga, S | 1 |
| Oki, E | 3 |
| Saeki, H | 1 |
| Kakeji, Y | 4 |
| Akagi, Y | 2 |
| Maehara, Y | 8 |
| Mori, M | 5 |
| Guven, DC | 1 |
| Guner, G | 1 |
| Aktas, BY | 1 |
| Aktepe, OH | 1 |
| Taban, H | 1 |
| Arik, Z | 1 |
| Sunami, E | 1 |
| Sugihara, K | 7 |
| Saito, Y | 1 |
| Takekuma, Y | 1 |
| Komatsu, Y | 2 |
| Sugawara, M | 1 |
| Chen, YG | 2 |
| Yeh, RH | 1 |
| Chang, PY | 2 |
| Dai, MS | 1 |
| Lai, SW | 1 |
| Ho, CL | 3 |
| Chen, YC | 1 |
| Hu, JM | 2 |
| Yang, SS | 1 |
| Huang, WY | 1 |
| Lee, CC | 2 |
| Hsiao, CW | 2 |
| Wu, CC | 2 |
| Jao, SW | 2 |
| Yang, JF | 1 |
| Lo, CH | 1 |
| Matsuda, K | 1 |
| Namiki, T | 1 |
| Ueno, M | 2 |
| Hashimoto, T | 3 |
| Hanafusa, T | 1 |
| Yokozeki, H | 1 |
| Yeh, YS | 1 |
| Tsai, HL | 1 |
| Huang, CW | 1 |
| Wei, PL | 1 |
| Sung, YC | 1 |
| Tang, HC | 1 |
| Wang, JY | 3 |
| Suga, Y | 1 |
| Takehana, K | 1 |
| Kabashima, A | 2 |
| Kimura, K | 1 |
| Sanefuji, K | 1 |
| Maekawa, S | 1 |
| Akiyama, T | 1 |
| Yasutomi, J | 1 |
| Kusashio, K | 1 |
| Matsumoto, M | 1 |
| Suzuki, T | 5 |
| Iida, A | 2 |
| Imamura, N | 1 |
| Yoshizumi, A | 1 |
| Harano, R | 1 |
| Udagawa, I | 1 |
| Ohtsuka, M | 1 |
| Baba, T | 1 |
| Kokuryo, T | 1 |
| Yamaguchi, J | 1 |
| Yokoyama, Y | 1 |
| Uehara, K | 2 |
| Ebata, T | 1 |
| Nagino, M | 2 |
| Matsuda, C | 4 |
| Ishiguro, M | 5 |
| Teramukai, S | 3 |
| Kajiwara, Y | 1 |
| Fujii, S | 1 |
| Kinugasa, Y | 3 |
| Nakamoto, Y | 4 |
| Kotake, M | 3 |
| Sakamoto, Y | 4 |
| Kurachi, K | 2 |
| Maeda, A | 2 |
| Komori, K | 1 |
| Tomita, N | 5 |
| Shimada, Y | 3 |
| Kotake, K | 5 |
| Watanabe, M | 7 |
| Mochizuki, H | 4 |
| Nakagawa, Y | 1 |
| Tago, T | 1 |
| Suzuki, K | 2 |
| Nishida, K | 1 |
| Maruyama, T | 1 |
| Shimazaki, J | 1 |
| Shimoda, M | 1 |
| Suzuki, S | 3 |
| Kou, K | 1 |
| Morishita, Y | 1 |
| Nobori, C | 1 |
| Uchima, Y | 1 |
| Aomatsu, N | 1 |
| Okada, T | 1 |
| Miyamoto, H | 1 |
| Kurihara, S | 1 |
| Wang, E | 1 |
| Hirakawa, T | 1 |
| Iwauchi, T | 1 |
| Morimoto, J | 1 |
| Yamagata, S | 1 |
| Nakazawa, K | 1 |
| Takeuchi, K | 1 |
| Hayashi, M | 1 |
| Nakamura, K | 1 |
| Terai, S | 2 |
| Okamoto, K | 3 |
| Sakai, S | 1 |
| Kinoshita, J | 1 |
| Hayashi, H | 1 |
| Oyama, K | 2 |
| Miyashita, T | 1 |
| Inokuchi, M | 1 |
| Tajima, H | 1 |
| Takamura, H | 2 |
| Ninomiya, I | 1 |
| Fushida, S | 1 |
| Ohta, T | 4 |
| Hiraki, M | 2 |
| Tanaka, T | 6 |
| Koga, F | 1 |
| Saito, A | 1 |
| Oza, N | 1 |
| Ikeda, O | 1 |
| Manabe, T | 1 |
| Miyoshi, A | 1 |
| Kitahara, K | 1 |
| Sato, S | 3 |
| Noshiro, H | 1 |
| Ueno, H | 2 |
| Nakatani, E | 2 |
| Ishikawa, T | 3 |
| Uetake, H | 2 |
| Egawa, T | 2 |
| Yasumasa, K | 2 |
| Murata, K | 6 |
| Ikawa, O | 2 |
| Shinji, S | 1 |
| Murotani, K | 1 |
| Matsui, S | 2 |
| Benson, AB | 1 |
| Nishizawa, T | 1 |
| Kinoshita, S | 1 |
| Sakuno, T | 1 |
| Fujiyama, Y | 1 |
| Kikuchi, M | 1 |
| Kaneko, H | 1 |
| Suzuki, H | 2 |
| Takahashi, M | 2 |
| Tomizawa, K | 2 |
| Hanaoka, Y | 2 |
| Toda, S | 2 |
| Moriyama, J | 2 |
| Matoba, S | 2 |
| Kuroyanagi, H | 2 |
| Hashimoto, M | 3 |
| Udagawa, H | 2 |
| Watanabe, G | 2 |
| Yoh, T | 1 |
| Wada, S | 1 |
| Kobayashi, A | 2 |
| Nakamura, Y | 4 |
| Kato, T | 5 |
| Nakayama, H | 1 |
| Okamura, R | 1 |
| Mizushima, T | 4 |
| Ide, Y | 2 |
| Ohashi, I | 1 |
| Fukunaga, M | 3 |
| Takemoto, H | 2 |
| Tamagawa, H | 1 |
| Hasegawa, J | 2 |
| Hata, T | 4 |
| Takemasa, I | 4 |
| Yamamoto, H | 5 |
| Sekimoto, M | 3 |
| Nezu, R | 3 |
| Doki, Y | 3 |
| Zhang, E | 1 |
| Cao, W | 1 |
| Cheng, C | 1 |
| Huo, BL | 1 |
| Wang, YH | 1 |
| Tsuchiya, N | 1 |
| Yamagishi, S | 1 |
| Ishibe, A | 1 |
| Matsuo, K | 1 |
| Misuta, K | 1 |
| Nakano, A | 1 |
| Sasaki, K | 4 |
| Katsumata, K | 2 |
| Nishimura, G | 2 |
| Morita, T | 3 |
| Koda, K | 4 |
| Matsuoka, J | 2 |
| Yamaguchi, Y | 2 |
| Usuki, H | 3 |
| Hamada, C | 5 |
| Kodaira, S | 4 |
| Saji, S | 2 |
| Tashiro, J | 2 |
| Yamaguchi, S | 4 |
| Ishii, T | 3 |
| Suzuki, A | 2 |
| Kondo, H | 3 |
| Morita, Y | 1 |
| Hara, K | 2 |
| Koyama, I | 1 |
| Yoshida, M | 4 |
| Ikejiri, K | 3 |
| Mochizuki, I | 2 |
| Takagane, A | 2 |
| Endo, T | 2 |
| Shinozaki, H | 2 |
| Takii, Y | 3 |
| Kameoka, S | 3 |
| Watanabe, T | 3 |
| Boku, N | 2 |
| Matsuoka, N | 1 |
| Ushimaru, Y | 1 |
| Kakimoto, Y | 1 |
| Toyoda, A | 1 |
| Endo, Y | 2 |
| Murakami, O | 1 |
| Kato, Y | 1 |
| Inoue, M | 1 |
| Kimura, T | 4 |
| Matsuda, Y | 1 |
| Sasakabe, H | 1 |
| Cheng, AL | 1 |
| Li, J | 1 |
| Vaid, AK | 1 |
| Ma, BB | 1 |
| Teh, C | 1 |
| Ahn, JB | 1 |
| Bello, M | 1 |
| Charoentum, C | 1 |
| Chen, LT | 1 |
| de Lima Lopes, G | 1 |
| Ho, GF | 1 |
| Kong, HL | 1 |
| Lam, KO | 1 |
| Liu, TS | 1 |
| Park, YS | 1 |
| Sriuranpong, V | 1 |
| Sudoyo, AW | 1 |
| Zhang, J | 1 |
| Zhang, SZ | 1 |
| Ciardiello, F | 1 |
| Köhne, CH | 1 |
| Shaw, M | 1 |
| Kim, TW | 1 |
| Abali, H | 1 |
| Yavuz, S | 1 |
| Calıkusu, Z | 1 |
| Seyrek, E | 1 |
| Sueda, T | 1 |
| Kudo, T | 2 |
| Sakai, D | 1 |
| Uemura, M | 2 |
| Nishimura, J | 2 |
| Ezoe, S | 1 |
| Matsumoto, K | 2 |
| Satoh, T | 2 |
| Konishi, K | 1 |
| Okuyama, M | 2 |
| Hiraoka, K | 1 |
| Nakagawa, T | 1 |
| Kim, C | 1 |
| Endo, S | 1 |
| Yamada, T | 1 |
| Nishijima, J | 1 |
| Okada, K | 3 |
| Oka, Y | 1 |
| Uemura, H | 1 |
| Omura, Y | 1 |
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| Tsushima, H | 1 |
| Nakao, K | 1 |
| Arizono, S | 1 |
| Makuuchi, M | 1 |
| Nukatsuka, M | 2 |
| Uchida, J | 6 |
| Oh-ie, S | 1 |
| Nomura, N | 1 |
| Ishitani, K | 1 |
| Miyauchi, T | 1 |
| Fuji, N | 1 |
| Omura, K | 1 |
| Ishida, F | 1 |
| Yamamitsu, S | 2 |
| Shirasaka, T | 5 |
| Yoshida, Y | 1 |
| Kosaki, G | 1 |
| Kurihara, M | 2 |
| Inada, T | 1 |
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| Ozawa, I | 1 |
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| Uchino, J | 5 |
| Inokuchi, K | 5 |
| Hattori, T | 10 |
| Kondo, T | 6 |
| Abe, O | 6 |
| Sugimachi, K | 6 |
| Watanabe, H | 2 |
| Sakakibara, N | 1 |
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| Takechi, T | 5 |
| Satake, H | 1 |
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| Tazawa, K | 2 |
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| Kuroki, Y | 2 |
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| Nosaka, S | 1 |
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| Hata, K | 1 |
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| Mamounas, EP | 3 |
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| Pazdur, R | 1 |
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| Colangelo, L | 3 |
| Sato, K | 1 |
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| Fujii, T | 1 |
| Terashima, M | 1 |
| Nakahara, H | 1 |
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| Ohki, S | 1 |
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| Fukushima, T | 2 |
| Shimada, H | 1 |
| Yamaguchi, M | 4 |
| Lin, JK | 1 |
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| Hsieh, RK | 1 |
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| Kinami, Y | 2 |
| Yamaguchi, A | 1 |
| Yoshikawa, K | 1 |
| Iwasaki, T | 1 |
| Amemiya, A | 1 |
| Emoto, T | 1 |
| Han, N | 1 |
| Itou, A | 1 |
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| Nakazawa, O | 2 |
| Morita, K | 2 |
| Kure, T | 2 |
| Terada, S | 2 |
| Matsunaga, T | 1 |
| Tsuji, Y | 1 |
| Miyazaki, E | 1 |
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| Kudo, H | 3 |
| Kuwa, K | 2 |
| Kasahara, N | 3 |
| Okamoto, R | 3 |
| Kawachi, Y | 3 |
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| Wada, M | 1 |
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| Shimura, H | 2 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT02836977] | 400 participants (Anticipated) | Interventional | 2016-03-31 | Active, not recruiting | |||
| Randomized Phase III Trial of Adjuvant Chemotherapy With UFT vs. Observation in Curatively Resected Stage II Colon Cancer[NCT00392899] | Phase 3 | 2,025 participants (Actual) | Interventional | 2006-10-31 | Completed | ||
| Randomized Phase III Study of UFT+Leucovorin vs. TS-1 as Adjuvant Treatment for Stage III Colon Cancer , and Investigate Predictive Factors Based on Gene Expression[NCT00660894] | Phase 3 | 1,535 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
| Phase III Randomized Controlled Clinical Study of UFT/LV Therapy Versus UFT/LV + PSK Therapy as Postoperative Adjuvant Therapy for Histological Stage IIIa and IIIb Colorectal Cancer[NCT00497107] | Phase 3 | 300 participants (Anticipated) | Interventional | 2007-07-31 | Recruiting | ||
| A Clinical Trial Comparing Oral Uracil/Ftorafur (UFT) Plus Leucovorin (LV) With 5-Fluorouracil (5-FU) Plus LV in the Treatment of Patients With Stages II And III Carcinoma of the Colon[NCT00378716] | Phase 3 | 1,608 participants (Actual) | Interventional | 1997-02-28 | Completed | ||
| A Clinical Trial to Assess the Relative Efficacy of 5-FU + Leucovorin, 5-FU + Levamisole, and 5-FU + Leucovorin + Levamisole in Patients With Dukes' B and C Carcinoma of the Colon[NCT00425152] | Phase 3 | 2,151 participants (Actual) | Interventional | 1989-07-31 | Completed | ||
| A Clinical Trial to Evaluate Postoperative Immunotherapy and Postoperative Systemic Chemotherapy in the Management of Resectable Colon Cancer[NCT00427570] | Phase 3 | 0 participants | Interventional | 1977-09-30 | Completed | ||
| A Clinical Trial to Evaluate the Postoperative Portal Vein Infusion of 5-Fluorouracil and Heparin in Patients With Resectable Adenocarcinoma of the Colon[NCT00427310] | Phase 3 | 1,158 participants (Actual) | Interventional | 1984-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
23 reviews available for tegafur and Cancer of Colon
| Article | Year |
|---|---|
Hypertriglyceridemia induced by S-1: A novel case report and review of the literature.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Combinations; Humans; Hypert | 2021 |
Uracil-tegafur vs fluorouracil as postoperative adjuvant chemotherapy in Stage II and III colon cancer: A nationwide cohort study and meta-analysis.
Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colectomy; Colonic Neoplasms; Disease | 2021 |
Applications of oral fluoropyrimidines in colon cancer: their role and new directions.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Co | 2003 |
[A case of para-aortic lymph node metastasis from colon cancer with complete response to uracil/tegafur plus leucovorin therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aorta; Colonic Neoplasms; Humans; Leucovorin; | 2014 |
[A case of disseminated carcinomatosis of the bone marrow with disseminated intravascular coagulation caused by advanced colon cancer successfully treated with SOX/bevacizumab].
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bone | 2014 |
The role of meta-analysis in cancer clinical trials.
Topics: Clinical Trials as Topic; Colonic Neoplasms; Humans; Meta-Analysis as Topic; Neoplasms; Rectal Neopl | 2009 |
[The current status of adjuvant chemotherapy of colonic cancer].
Topics: Antimetabolites, Antineoplastic; Carnitine O-Palmitoyltransferase; Chemotherapy, Adjuvant; Colonic N | 2009 |
[A long-term survival case in advanced mucinous cystadenocarcinoma of the appendix using cytoreductive surgery and S-1/CDDP chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Appendix; Cisplatin; Colonic Neoplasms; Cystadenocar | 2011 |
[A case of peritoneal dissemination that exhibited a complete response to systemic chemotherapy following the resection of primary colon cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colostomy; Combined Modality Ther | 2012 |
[Recent advances in chemotherapy for digestive cancers with special references to gastric and colonic cancers].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colonic Neoplasms; Docetaxe | 2003 |
[Chemotherapy for colon cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colonic Neoplasms; Deoxy | 2003 |
Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 2004 |
[Adjuvant treatment of colorectal cancer].
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Capeci | 2006 |
[Standard chemotherapy for colonic neoplasms].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplas | 2007 |
[Adjuvant chemotherapy for colorectal cancer in Japan-current state and problem areas].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colonic Neopla | 2007 |
UFT (tegafur and uracil) as postoperative adjuvant chemotherapy for solid tumors (carcinoma of the lung, stomach, colon/rectum, and breast): clinical evidence, mechanism of action, and future direction.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Colonic Ne | 2007 |
Chemotherapy in alimentary tract malignomas.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Cytarabine; Doxor | 1981 |
Regional and systemic chemotherapy for advanced colorectal cancer. A review.
Topics: Antineoplastic Agents; Aspartic Acid; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; D | 1983 |
Treatment of cultured human colon carcinoma cells with fluorinated pyrimidines.
Topics: Cell Line; Cell Survival; Colonic Neoplasms; Culture Media; Drug Evaluation, Preclinical; Fluorourac | 1980 |
[Fundamental studies on the surgical adjuvant chemotherapy to support the clinical efficacies].
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast N | 1997 |
[Conceptual changes in cancer chemotherapy--biochemical modulation of 5-FU].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; | 2000 |
[Chemotherapy of gastrointestinal tumors (review of the literature)].
Topics: Ancitabine; Carcinoma, Hepatocellular; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combination; Fl | 1978 |
Potentiation of antimetabolite action by alkylating agents.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brea | 1985 |
57 trials available for tegafur and Cancer of Colon
| Article | Year |
|---|---|
Prospective observational study of the efficacy of oral uracil and tegafur plus leucovorin for stage II colon cancer with risk factors for recurrence using propensity score matching (JFMC46-1201).
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2022 |
Efficacy and feasibility of S-1 plus oxaliplatin (C-SOX) for treating patients with stage III colon cancer (KSCC1303): final analysis of 3-year disease-free survival.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva | 2020 |
Maintenance tegafur-uracil versus observation following an adjuvant oxaliplatin-based regimen in patients with stage III colon cancer after radical resection: study protocol for a randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap | 2017 |
A randomised-controlled trial of 1-year adjuvant chemotherapy with oral tegafur-uracil versus surgery alone in stage II colon cancer: SACURA trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2018 |
Prospective Multicenter Study on the Prognostic and Predictive Impact of Tumor Budding in Stage II Colon Cancer: Results From the SACURA Trial.
Topics: Aged; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Epithelial-Mesenchymal Trans | 2019 |
A phase II study of combined chemotherapy with 5-week cycles of S-1 and CPT-11 plus bevacizumab in patients with metastatic colon cancer.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva | 2013 |
Safety analysis of two different regimens of uracil-tegafur plus leucovorin as adjuvant chemotherapy for high-risk stage II and III colon cancer in a phase III trial comparing 6 with 18 months of treatment: JFMC33-0502 trial.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Col | 2014 |
S-1 as adjuvant chemotherapy for stage III colon cancer: a randomized phase III study (ACTS-CC trial).
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva | 2014 |
Randomized phase II study of S-1 dosing schedule for resected colorectal cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplasti | 2015 |
Randomized phase III trial of treatment duration for oral uracil and tegafur plus leucovorin as adjuvant chemotherapy for patients with stage IIB/III colon cancer: final results of JFMC33-0502.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Colonic Neoplasms; Dru | 2015 |
A randomized phase III trial comparing S-1 versus UFT as adjuvant chemotherapy for stage II/III rectal cancer (JFMC35-C1: ACTS-RC).
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva | 2016 |
A phase I study of combination therapy with S-1 and irinotecan (CPT-11) in patients with advanced colorectal cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Col | 2009 |
[Efficacy and side effects of combination therapy of oxaliplatin and S-1 for colorectal cancer].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antineoplastic Combined Chemotherapy Protocols; Colo | 2011 |
Safety of UFT/LV and S-1 as adjuvant therapy for stage III colon cancer in phase III trial: ACTS-CC trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuva | 2012 |
Study protocol of the SACURA trial: a randomized phase III trial of efficacy and safety of UFT as adjuvant chemotherapy for stage II colon cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Clinical Protocols; Colonic | 2012 |
Optimal schedule of adjuvant chemotherapy with S-1 for stage III colon cancer: study protocol for a randomized controlled trial.
Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Clinical Protocols; Colectomy; Colonic Neop | 2013 |
[Hepatic recurrence after prophylactic hepatic arterial infusion of 5-fluorouracil for Dukes' C colorectal cancer--correlation with the expression of dihydropyrimidine dehydrogenase in the primary tumor].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol | 2002 |
Oral tegafur-uracil plus folinic acid versus intravenous 5-fluorouracil plus folinic acid as adjuvant chemotherapy of colon cancer.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; | 2003 |
Randomized controlled trial of the efficacy of adjuvant immunochemotherapy and adjuvant chemotherapy for colorectal cancer, using different combinations of the intracutaneous streptococcal preparation OK-432 and the oral pyrimidines 1-hexylcarbamoyl-5-flu
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 2004 |
[Multicenter comparative study of the recurrence-inhibitory effect of oral fluoropyrimidine drugs in patients with colorectal cancer following curative resection].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Pr | 2005 |
[Clinical evaluation of chemotherapy with irinotecan (CPT-11), l-leucovorin (l-LV), 5-fluorouracil (5-FU), and UFT for metastatic or recurrent colorectal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug A | 2005 |
Oral uracil and tegafur plus leucovorin compared with intravenous fluorouracil and leucovorin in stage II and III carcinoma of the colon: results from National Surgical Adjuvant Breast and Bowel Project Protocol C-06.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms | 2006 |
Oral uracil and tegafur plus leucovorin compared with intravenous fluorouracil and leucovorin in stage II and III carcinoma of the colon: results from National Surgical Adjuvant Breast and Bowel Project Protocol C-06.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms | 2006 |
Oral uracil and tegafur plus leucovorin compared with intravenous fluorouracil and leucovorin in stage II and III carcinoma of the colon: results from National Surgical Adjuvant Breast and Bowel Project Protocol C-06.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms | 2006 |
Oral uracil and tegafur plus leucovorin compared with intravenous fluorouracil and leucovorin in stage II and III carcinoma of the colon: results from National Surgical Adjuvant Breast and Bowel Project Protocol C-06.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms | 2006 |
Diverticular disease in patients with colon cancer: subgroup analysis of national surgical adjuvant breast and bowel project protocol C-06.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cohort Studies; Colonic Neoplasms; Diverticulum, Colon; | 2006 |
Quality of life in operable colon cancer patients receiving oral compared with intravenous chemotherapy: results from National Surgical Adjuvant Breast and Bowel Project Trial C-06.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adj | 2007 |
A comparative study of oral tegafur and intravenous 5-fluorouracil in patients with metastatic colorectal cancer.
Topics: Administration, Oral; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Injections, | 1983 |
[Joint clinical Phase II study of SF-SP].
Topics: Clinical Trials as Topic; Colonic Neoplasms; Delayed-Action Preparations; Drug Evaluation; Female; F | 1984 |
[Evaluation of preoperative administration of N1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) suppository in surgical adjuvant chemotherapy for large bowel cancer].
Topics: Adult; Colonic Neoplasms; Colostomy; Female; Fluorouracil; Humans; Male; Middle Aged; Preoperative C | 1984 |
Methyl-CCNU and ftorafur in treatment of rectosigmoidal tumors and ftorafur capsules in treatment of colorectal tumors.
Topics: Capsules; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Huma | 1981 |
[Cooperative study of surgical adjuvant chemotherapy for colorectal cancer. Cooperative Study Group of Surgical Adjuvant Chemotherapy for Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Admi | 1995 |
[Cooperative Study of Surgical Adjuvant Chemotherapy for Colorectal Cancer (third report): five-year results after surgery].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Coloni | 1993 |
[Cooperative Study of Surgical Adjuvant Chemotherapy for Colorectal Cancer (fourth report): five-year results after surgery].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Admi | 1993 |
[Low-dose cisplatin added to continuous infusion of 5-fluorouracil or oral administration of UFT for inoperable advanced or recurrent colorectal cancer].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Coloni | 1997 |
Postsurgical sequential methotrexate, fluorouracil, and leucovorin for advanced colorectal carcinoma: a preliminary study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Dis | 1997 |
Phase I trial of uracil-tegafur (UFT) plus oral leucovorin: 28-day schedule.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Coloni | 1998 |
[Adjuvant chemotherapy with UFT or UFT with OK-432 to patients with gastric and colorectal cancer. Kanto Adjuvant Study Group].
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colo | 1998 |
[Clinical evaluation of S-1, a new anticancer agent, in patients with advanced gastrointestinal cancer. S-1 Cooperative Gastrointestinal Study Group].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Administration Schedu | 1999 |
UFT plus calcium folinate vs 5-FU plus calcium folinate in colon cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; | 1999 |
UFT/leucovorin vs 5-FU/leucovorin in colon cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, | 2000 |
[Optimal dosage of UFT in a weekday-on/weekend-off schedule as a postoperative adjuvant chemotherapy for colorectal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration | 2000 |
Immunomodulatory effects of low dose cis-Diaminedichloroplatinum (cisplatin) combined with UFT and PSK in patients with advanced colorectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Combined Modalit | 2002 |
Phase II trial of ftorafur with mitomycin C versus ftorafur with methyl-CCNU in untreated colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Drug Evaluation; Drug Ther | 1978 |
[Multicenter cooperative study of pre- and post-operative adjuvant chemotherapy in the treatment of colorectal cancer. North Kyushu Co-operative Study Group for Cancer Chemotherapy].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Coloni | 1992 |
[Comparative study of UFT plus mitomycin C and UFT plus doxorubicin in adenocarcinoma. Hirosaki Cooperative Group of Cancer Chemotherapy].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Proto | 1992 |
[Clinical effect of postoperative adjuvant chemotherapy for advanced colorectal cancer--comparisons of between tegafur (FT) and UFT].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 1991 |
[A multicenter comparative study in patients with liver metastasis to compare tegafur in new forms with existing drugs. SF-RC.SF-SP Comparative Study Group].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Biological Availability; Capsules; Colonic Neo | 1989 |
[Outcome of adjuvant mifurol chemotherapy in patients with resected colonic carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Th | 1989 |
[Cooperative study of surgical adjuvant chemotherapy of colorectal carcinoma (second study): a preliminary report. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Drug A | 1989 |
[Cooperative study of surgical adjuvant chemotherapy of colorectal carcinoma (second study): 3-year survival after surgery of non-curatively resected patients. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Drug A | 1989 |
Comparison of oral ftorafur and intravenous 5-fluorouracil in patients with advanced cancer of the stomach, colon or rectum.
Topics: Actuarial Analysis; Adenocarcinoma; Aged; Colonic Neoplasms; Female; Fluorouracil; Humans; Male; Mid | 1986 |
[Adjuvant chemotherapy of colorectal cancer--results of prospective randomized trials].
Topics: Administration, Rectal; Adult; Aged; Colonic Neoplasms; Drug Administration Schedule; Female; Humans | 1986 |
[Comparative clinical study of SF-SP therapy and SF-SP plus BH-AC therapy in gastrointestinal cancer. Tokyo Cancer Chemotherapy Cooperative Study Group].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cytarabine; Delayed- | 1986 |
[Clinical trial of UFT in malignancies--an analysis of 337 patients. Co-operative Group for Clinical Study of UFT].
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, | 1986 |
Oral ftorafur versus intravenous 5-fluorouracil. A comparative study in patients with colorectal cancer.
Topics: Administration, Oral; Adult; Aged; Blood Platelets; Colonic Neoplasms; Female; Fluorouracil; Humans; | 1987 |
[Clinical effect of postoperative adjuvant immunochemotherapy with the FT-207 suppository and PSK in colorectal cancer patients. Colorectal Cancer Chemotherapy Group in Hokuriku].
Topics: Administration, Oral; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Hu | 1988 |
[A cooperative study of surgical adjuvant chemotherapy of colorectal cancer (second report): 3-year survival rate. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Humans; Mitomycin; M | 1988 |
[Results of phase III study of lentinan].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neopl | 1985 |
[Studies on the effects of adjuvant chemotherapy on the survival period of patients with colorectal carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Th | 1985 |
226 other studies available for tegafur and Cancer of Colon
| Article | Year |
|---|---|
[A Case Report for Peritoneal Recurrences by Laparoscopic Surgery after Colorectal Cancer Resection].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colonic Neoplasms; Colorectal Neo | 2022 |
Benefit of Uracil-Tegafur Used as a Postoperative Adjuvant Chemotherapy for Stage IIA Colon Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cohort Studies; Colonic Neop | 2022 |
Prognostic factors in patients with high-risk stage II colon cancer after curative resection: a post hoc analysis of the JFMC46-1201 trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Humans; N | 2023 |
Defining the Optimal Regimen for Stage III Colon Cancer: Concerns with Study Design.
Topics: Chemotherapy, Adjuvant; Colonic Neoplasms; Humans; Leucovorin; Oxaliplatin; Tegafur | 2020 |
Reply to the Letter to the Editor "Defining the Optimal Regimen for Stage III Colon Cancer: Concerns With Study Design" by Guven DC et al.
Topics: Chemotherapy, Adjuvant; Colonic Neoplasms; Humans; Leucovorin; Oxaliplatin; Tegafur | 2020 |
Oral tegafur-uracil as metronomic therapy following intravenous FOLFOX for stage III colon cancer.
Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Co | 2017 |
Tegafur/gimeracil/oteracil (TS-1)-induced erythroderma with an extensive mucosal involvement and hand-foot syndrome.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neop | 2017 |
Lentinan diminishes apoptotic bodies in the ileal crypts associated with S-1 administration.
Topics: Administration, Intravenous; Animals; CD11b Antigen; Cell Line, Tumor; Colonic Neoplasms; Drug Combi | 2017 |
Completely Responsive Multiple Liver Recurrence of Colon Cancer Treated Using Chemotherapy with Oral S-1 and Oxaliplatin Plus Bevacizumab : A Case Report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colonic Neoplasms; Drug Combinati | 2017 |
[Severe Therapy-Related Pancytopenia Caused by UFT and LV in a Patient with Ascending Colon Cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colon, Ascending; Colonic Neoplasms; Granulocy | 2017 |
Pre-exposure to Fluorouracil Increased Trifluridine Incorporation and Enhanced its Anti-tumor Effect for Colorectal Cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, | 2018 |
[A Case of Synchronous Liver Metastasis of Ascending Colon Cancer with Pathological Complete Response to S-1/Oxaliplatin (SOX) and Bevacizumab].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colon, Ascending; Colonic Neoplas | 2018 |
[A Case of Sister Mary Joseph's Nodule from Transverse Colon Cancer Effectively Treated with SOX plus Bevacizumab Chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colon, Transverse; Colo | 2018 |
[A Case of Spontaneous Esophageal Rupture That Required Operation during Adjuvant Chemotherapy for Transverse Colon Cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colon, Transverse; Col | 2018 |
An Unusual Case of Acute Liver Failure Caused by Adjuvant Oral Tegafur-Uracil with Folinate Therapy for Colon Cancer Patient: a Case Report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Humans; Leucovorin; Liver F | 2020 |
[A case of metastatic colon cancer effectively treated by XELOX and IRIS].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colonic Neoplasms; | 2013 |
[A retrospective study of UFT and oral leucovorin combination adjuvant chemotherapy for patients over 76 years old with stage III colon cancer].
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemo | 2013 |
[A case of metastatic acsending colon cancer showing sustained complete response to chemotherapy with SOX and followed UFT].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Combinations; Female; | 2013 |
A systemic analysis of S-1 regimens for treatment of patients with colon cancer.
Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptot | 2014 |
Inferior oncological prognosis of surgery without oral chemotherapy for stage III colon cancer in clinical settings.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemot | 2014 |
Adaptation of international guidelines for metastatic colorectal cancer: an asian consensus.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot | 2014 |
Is fluoropyrimidindes without oxaliplatin optimal for the adjuvant treatment of mainstream stage III colon cancer?
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Combinations; Female; Humans | 2015 |
Reply to the letter to the editor 'Is fluoropyrimidindes without oxaliplatin optimal for the adjuvant treatment of mainstream stage III colon cancer?' by Abali et al.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Combinations; Female; Humans | 2015 |
Safety and pharmacokinetics of S-1 in a recurrent colon cancer patient with chronic myeloid leukemia treated with dasatinib: a case report.
Topics: Aged; Antimetabolites, Antineoplastic; Area Under Curve; Colonic Neoplasms; Dasatinib; Drug Combinat | 2014 |
[A case of liver and para-aortic lymph node metastasis of colorectal cancer responding to S-1].
Topics: Aged; Antimetabolites, Antineoplastic; Aorta; Colonic Neoplasms; Drug Combinations; Female; Humans; | 2015 |
[A case of surgery for stenosis of the colon from recurrent gastric cancer].
Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Combinations; | 2014 |
[A case of metastatic colon carcinoma following curative resection for advanced gastric cancer associated with metastases to the liver and gallbladder].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Combin | 2014 |
Stage III Colon Cancer: The Individualized Strategy of Adjuvant Chemotherapy for Aged Under and Over 70.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoth | 2015 |
[A Case of Adenosquamous Carcinoma of the Ascending Colon].
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Adenosquamous; Chemotherapy, Adjuvant; Colectomy; | 2015 |
[A Successful Case of Treatment of Colonic Metastasis and Peritoneal Recurrence of Type 4 Gastric Cancer by Using Colectomy and Chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colectomy; Colonic Neo | 2015 |
[A Case of Ascending Colon Cancer with Extra Iliac Lymph Node Metastases].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colon, Ascending; Colonic Ne | 2015 |
[Adjuvant Systemic Chemotherapy with S-1/Oxaliplatin or mFOLFOX6 after Curative Resection of Distant Metastases in Patients with Colorectal Cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Dru | 2016 |
[A Case of Alternate-Day Treatment with S-1 in a Patient with Multiple Lung Metastases of Colon Cancer].
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug | 2016 |
Adjuvant chemotherapy with tegafur/uracil for more than 1 year improves disease-free survival for low-risk Stage II colon cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Col | 2016 |
[Comparison of the Cost-Effectiveness of the SOX and COX Regimens in Patients with Unresectable Advanced and Recurrent Colorectal Cancer Using a Clinical Decision Analysis Approach].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colonic Neoplasms; Cost-Benefit | 2016 |
Oncologic Outcomes of Oral Adjuvant Chemotherapy Regimens in Stage III Colon Cancer: Tegafur-Uracil Plus Leucovorin Versus Capecitabine.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Capecitabine; Chemotherapy, Adjuvant; Colo | 2017 |
[A case of interstitial pneumonia induced by S-1/irinotecan combination therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Combinat | 2008 |
[A patient in whom oral UFT/Leucovorin therapy proved markedly effective for lung metastasis after surgery for colon cancer].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Human | 2008 |
[A case of simultaneous hepatic metastases of ascending colon cancer responding completely to tegafur/uracil plus oral Leucovorin therapy after primary lesion resection].
Topics: Administration, Oral; Aged, 80 and over; Colonic Neoplasms; Female; Humans; Leucovorin; Liver Neopla | 2008 |
[Three cases with liver metastasis from gastric or colon cancer successfully treated with S-1 combined with CPT- 11].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; | 2008 |
Relationships of insulin-like growth factor-1 receptor and epidermal growth factor receptor expression to clinical outcomes in patients with colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Colorectal Neoplasm | 2009 |
[A case of peritonitis carcinomatosa from goblet cell carcinoid of the appendix treated by intraperitoneal paclitaxel and systemic S-1 chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Colonic Neoplasms; Colonoscop | 2008 |
[A case of multiple lymph node metastases from transverse colon cancer successfully treated with oral tegafur/uracil (UFT)/Leucovorin (LV)].
Topics: Administration, Oral; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colon, Tran | 2008 |
[A case of metronomic chemotherapy as an alternative cancer therapy for palliation].
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplasti | 2009 |
Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy.
Topics: AC133 Antigen; Adult; Aged; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Biomarkers | 2009 |
[A case of advanced colon cancer treated with preoperative chemotherapy (IRIS) leading to clinical complete response].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Chemotherapy | 2009 |
[Effectiveness of S-1 plus CPT-11 therapy for an elderly patient with recurrent colon cancer].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Ch | 2009 |
The necessity of chemotherapy in T3N0M0 colon cancer without risk factors.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Col | 2009 |
[A case of simultaneous bilateral metastatic ovarian tumor of colon cancer followed by FOLFOX4 Regimen and oral tegafur/uracil+oral leucovorin after R0 operation].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colectomy; C | 2009 |
[The efficacy of S-1 monotherapy as a 2nd/3rd-line therapy for unresectable recurrent colon cancer: Kanagawa conference of clinical oncology (KCCO)].
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dise | 2009 |
[Huge ascending colon carcinoma, treated successfully with S-1 plus CPT-11, followed by significant tumor reduction and curative resection--a case report].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Ch | 2009 |
[A case of effective treatment with UFT/LV chemotherapy for para-aortic lymph node metastasis from colonic cancer 8 years after colectomy].
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol | 2009 |
[A case of advanced right colonic cancer successfully treated by surgery and post operative chemotherapy].
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, | 2009 |
[A case of colon cancer with multiple liver metastases responding ot S-1 as third-line treatment following FOLFIRI and FOLFOX].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Carcinoembryonic Antigen | 2010 |
[A case of fluoropyrimidine-resistant recurrent colon cancer successfully treated with weekly administration of irinotecan].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoembryonic Antigen; Coloni | 2010 |
[Long survival of a colon cancer case with synchronous multiple liver metastases responding to S-1].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Combinations; Female; | 2010 |
Characterization of a novel lymph node metastasis model from human colonic cancer and its preclinical use for comparison of anti-metastatic efficacy between oral S-1 and UFT/ LV.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; Drug C | 2010 |
Irinotecan overcomes the resistance to 5-fluorouracil in human colon cancer xenografts by down-regulation of intratumoral thymidylate synthase.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Blotting | 2010 |
[Pharmacokinetic study of S-1 for the treatment of peritoneal metastasis from colon cancer--using a mouse peritoneal metastasis model].
Topics: Administration, Oral; Animals; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; Drug Com | 2010 |
[Risk associated with severe hematological toxicity in patients with advanced or recurrent colonic cancer receiving combination chemotherapy of S-1 and irinotecan hydrochloride].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Ch | 2010 |
[A case of advanced colon cancer with metastases to both supraclavicular and para-aortic lymph nodes effectively treated by radiation and S-1 therapy].
Topics: Administration, Oral; Colonic Neoplasms; Combined Modality Therapy; Drug Combinations; Female; Human | 2010 |
[A case of lung metastases of colon cancer demonstrating complete response for more than five years after treatment with UFT].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Femal | 2010 |
[A case of drug-induced interstitial pneumonia caused by S-1 and CPT-11 combination therapy for advanced colon cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Combinat | 2011 |
[Pancreatoduodenectomy for locally advanced ascending colon cancer after neoadjuvant chemotherapy (mFOLFOX6)].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neopl | 2011 |
Long-term survival results of surgery alone versus surgery plus UFT (Uracil and Tegafur)-based adjuvant therapy in patients with stage II colon cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonic Neo | 2011 |
[The feasibility of oral fluoropyrimidines as adjuvant chemotherapy after resection and local coagulation therapy of colorectal liver metastases].
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemothe | 2011 |
[A case of pathological complete response after treatment with uracil/tegafur (UFT) and folinate (Leucovorin) for liver metastasis of colon cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Female | 2011 |
[A case of laparoscopic radiofrequency ablation for liver metastatic tumor from colorectal carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Catheter Ablation; Colonic Neoplasms; Female; | 2011 |
[A case of lung metastases after surgery for colon cancer demonstrating complete response for more than six years after treatment with UFT/LV].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Humans; Leucovorin; Lung | 2011 |
Dacryoendoscopic observation and incidence of canalicular obstruction/stenosis associated with S-1, an oral anticancer drug.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Colonic Neopl | 2012 |
[Marked response to oral administration of UFT and leucovorin for liver metastases from colon cancer in an elderly patient].
Topics: Administration, Oral; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colonic Neo | 2012 |
[A retrospective study of UFT and oral leucovorin plus PSK combination adjuvant chemotherapy in patients with stage III colon cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Leucovori | 2012 |
[A case of stage IV colon cancer effectively treated with tegafur uracil/calcium folinate in a patient on hemodialysis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; Combined Modality Ther | 2012 |
Abrogation of the accelerated blood clearance phenomenon by SOXL regimen: promise for clinical application.
Topics: Administration, Metronomic; Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplas | 2013 |
Oral uracil/ftorafur (UFT) plus leucovorin as first-line chemotherapy and salvage therapy with weekly high-dose 5-fluorouracil/leucovorin for the treatment of metastatic colorectal cancer.
Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; D | 2002 |
[A case of multiple liver metastases from colon cancer successfully treated with modified pharmacokinetic modulating chemotherapy using Leucovorin].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Col | 2002 |
[Two patients with recurrent colon cancer who underwent surgery following a combination of irinotecan and UFT].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptoth | 2002 |
Therapy-related erythroleukemia caused by the administration of UFT and mitomycin C in a patient with colon cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, | 2003 |
Role of platelet-derived endothelial cell growth factor/thymidine phosphorylase in fluoropyrimidine sensitivity.
Topics: Antimetabolites; Antimetabolites, Antineoplastic; Colonic Neoplasms; Fluorouracil; Gene Expression R | 2003 |
NICE recommends new treatment for breast and bowel cancer.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; | 2003 |
[A case of multiple liver metastases from colon cancer successfully treated with pharmacokinetic modulating chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neop | 2003 |
[A case of advanced colon cancer with peritoneal dissemination completely responding to TS-1].
Topics: Adenocarcinoma; Administration, Oral; Antimetabolites, Antineoplastic; Colectomy; Colonic Neoplasms; | 2004 |
[A case of highly advanced ascending colon cancer with multiple bone and liver metastases and pleuritis carcinomatosa treated with pharmacokinetic modulating chemotherapy and low-dose CPT-11].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Coloni | 2004 |
Black lunula caused by Tegafur.
Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonic Neoplasms; Female; Humans; Na | 2004 |
Oral administration of uracil-tegafur (UFT) inhibits liver micrometastasis of human colon cancer in an orthotopic nude mouse model and its early detection system.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy | 2004 |
Esophageal cancer with colonic metastasis successfully treated by chemoradiotherapy followed by chemotherapy with S-1 and cisplatin.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol | 2004 |
Immunohistochemical evaluation of thymidylate synthase (TS) and p16INK4a in advanced colorectal cancer: implication of TS expression in 5-FU-based adjuvant chemotherapy.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Chemotherapy, Adjuvant; Colonic Neoplasms; C | 2004 |
Effects of oral 5-fluorouracil drugs on hepatic fat content in patients with colon cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Chi-Square | 2005 |
[Combination chemotherapy with oral TS-1 and low-dose CPT-11 by hepatic arterial infusion for multiple hepatic metastases from colon cancer--a case report].
Topics: Adenocarcinoma; Administration, Oral; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocol | 2005 |
[A case of transverse colon cancer with left supraclavicular lymph node metastasis and paraaortic lymph node metastases responding to TS-1].
Topics: Antimetabolites, Antineoplastic; Aorta; Biomarkers, Tumor; CA-19-9 Antigen; Clavicle; Colectomy; Col | 2005 |
[A case of colorectal cancer effectively treated with UFT/LV].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Mo | 2005 |
[A case of colon cancer with multiple liver, lung and bone metastases successfully treated with combined weekly high-dose 5-FU (WHF) chemotherapy with UFT and CPT-11].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Colect | 2005 |
[Efficacy of tegafur/uracil plus oral leucovorin therapy for advanced or recurrent colorectal cancer].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms | 2005 |
[A case of multiple hepatic and peritoneal metastases from colon cancer responding to oral UFT+leucovorin chemotherapy].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Col | 2005 |
[A case of peritoneal dissemination disappeared by CPT-11 + TS-1 combination chemotherapy].
Topics: Administration, Oral; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Ant | 2005 |
[A case of recurrent colon cancer responding completely to uracil/tegafur (UFT) plus oral leucovorin (LV) therapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; | 2005 |
5-Fluorouracil cardiotoxicity induced by alpha-fluoro-beta-alanine.
Topics: Aged; Antimetabolites, Antineoplastic; beta-Alanine; Cardiovascular Diseases; Colonic Neoplasms; Dru | 2005 |
[A case of advanced colon cancer with metastases to both para-aortic lymph nodes and cervical vertebrae effectively treated by TS-1 therapy].
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Aorta; Cecal Neoplasms; Cervical Vertebrae; C | 2006 |
[Efficacy of the combined use of taurine for hyperbilirubinemia caused by UFT therapy after surgery for colonic cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemotherapy, Adjuvant; Colonic Neoplasms; Dr | 2006 |
[Second-line chemotherapy with pharmacokinetic modulating chemotherapy for unresectable colorectal carcinoma recurrences resistant to 5-FU-based chemotherapy].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chronotherapy; Co | 2006 |
[Complete response to CPT-11 and UFT/LV combination therapy in a case with simultaneous multiple lung metastases from colon cancer].
Topics: Adenocarcinoma; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neop | 2006 |
[A patient with hepatic, pulmonary, and nodal metastases of colon cancer responding to CPT-11/TS-1 therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colectomy; Colonic Neoplasms; Co | 2006 |
[Retrospective analysis of tegafur/uracil (UFT) plus oral leucovorin (LV) regimen in patients with advanced colorectal cancer].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2006 |
[Multiple hepatic metastases of colon cancer responding to combined therapy with TS-1 and CPT-11--a case report].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasm | 2006 |
[A case of non-curatively resected colon cancer with liver and lymph node metastases treated by TS-1/CPT-11 combination therapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoembryonic | 2006 |
[Two metastatic colonic cancer patients successfully treated by combination therapy of tegafur/uracil (UFT) and oral Leucovorin].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colon, S | 2006 |
[Partial response of liver metastasis from colon cancer following intermittent oral administration of TS-1 after intra-hepatic arterial single injection of CDDP, doxorubicin and 5-FU].
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Pr | 2006 |
Complete response of highly advanced colon cancer with multiple lymph node metastases to irinotecan combined with UFT: report of a case.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Col | 2006 |
[Successful low-dose TS-1 administration in an elderly colon cancer patient with liver metastasis].
Topics: Adenocarcinoma; Aged, 80 and over; Antimetabolites, Antineoplastic; Appendiceal Neoplasms; Colonic N | 2007 |
[A case of ascending colon cancer with enlarged metastatic lymph nodes around superior mesenteric arterial root that responded dramatically to S-1 and CPT-11 combination chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colectomy; Colon, Ascending; Colonic N | 2007 |
UFT/leucovorin and mitomycin C as salvage treatment in patients with advanced colorectal cancer - a retrospective analysis.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colonic Neo | 2007 |
Enhancement of antitumor effect of tegafur/uracil (UFT) plus leucovorin by combined treatment with protein-bound polysaccharide, PSK, in mouse models.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Colonic Neoplasms; Disease Models, Animal; Dr | 2007 |
[An elderly case of recurrent colon cancer responding to weekly S-1 chemotherapy leading to partial response].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; | 2008 |
[Primary lung cancer that I was preoperative and needed discrimination for and one example of the repetition cancer of the colon].
Topics: Colonic Neoplasms; Colonoscopy; Drug Combinations; Female; Humans; Lung Neoplasms; Middle Aged; Neop | 2007 |
[A long survival case of advanced colon cancer with lung metastasis and cancerous pleuritis responding to CPT-11 and S-1 combination therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Combinat | 2008 |
[Multiple hepatic metastases and ovarian metastases of colon cancer responding to combined therapy with S-1 and CPT-11--a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Combinations; | 2008 |
Anti-angiogenic effect of 5-Fluorouracil-based drugs against human colon cancer xenografts.
Topics: Angiogenesis Inhibitors; Animals; Capecitabine; Colonic Neoplasms; Deoxycytidine; Drug Combinations; | 2008 |
[Effects of 5'-deoxy-5-fluorouridine on human gastrointestinal and breast cancers xenografted to nude mice].
Topics: Adenocarcinoma; Administration, Oral; Animals; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Femal | 1984 |
[Clinical trial on the effect of tegafur (SF-SP)].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Capsules; Carcinoma, Intraductal, Noninfiltrating | 1984 |
Continuous intravenous administration of 1-(2-tetrahydrofuryl)-5-fluorouracil [FT] by intravenous hyperalimentation (IVH)--stability of FT in IVH solution and tumor levels of 5-fluorouracil (5-FU).
Topics: Colonic Neoplasms; Dose-Response Relationship, Drug; Fluorouracil; Humans; Parenteral Nutrition, Tot | 1983 |
Phase II study of ftorafur in previously untreated and treated patients with advanced colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male; | 1983 |
[Cooperative phase II study of spansule tegafur (SF-SP)].
Topics: Administration, Oral; Aged; Breast Neoplasms; Capsules; Colonic Neoplasms; Delayed-Action Preparatio | 1984 |
Phase I-II studies of oral tegafur (ftorafur).
Topics: Administration, Oral; Bone Marrow; Breast Neoplasms; Colonic Neoplasms; Dose-Response Relationship, | 1983 |
[Cooperative phase II study of releasing tegafur (SF-SP) against advanced digestive cancers].
Topics: Administration, Oral; Adult; Aged; Colonic Neoplasms; Delayed-Action Preparations; Digestive System | 1984 |
[Constant intra-aortic infusion chemotherapy for advanced abdominal cancer--a technic and the effect in patients with peritoneal metastases].
Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Coloni | 1984 |
[Experimental chemotherapy of human gastrointestinal and breast cancers in nude mice and its correlation to clinical effect].
Topics: Adenocarcinoma; Adult; Aged; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Pr | 1984 |
[Clinical trials of plasma exchange therapy in patients with recurrent colon cancer].
Topics: Abdominal Neoplasms; Adenocarcinoma; Administration, Oral; Adult; Aged; Colectomy; Colonic Neoplasms | 1984 |
Enhanced accumulation of 5-fluorouracil in human tumors in athymic mice by co-administration of Ftorafur and uracil.
Topics: Animals; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Mice; Mice, Nude; Neopl | 1984 |
[Evaluation of tegafur encapsulated with slow-releasing granules (SF-SP) for patients with cancer of the digestive organs].
Topics: Administration, Oral; Adult; Aged; Capsules; Colonic Neoplasms; Delayed-Action Preparations; Drug Ev | 1984 |
[Effect of local moderate hyperthermia in combination with N-nitroso-1,3-bis-(2-chloroethyl)urea (BCNU) and 5-fluoro-(tetrahydro-2-furyl)uracil (ftorafur) on induced autochthonous colonic cancers in the rat. 3: Polychemotherapy in combination with hyperth
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Carmustine; Colon; Colonic Neo | 1984 |
Chemoprevention of development of colonic adenomatosis and carcinomatosis with 5-fluorouracil and ftorafur on animal model.
Topics: Adenoma; Animals; Carcinoma; Colon; Colonic Neoplasms; Female; Fluorouracil; Methylnitrosourea; Neop | 1980 |
Comparative efficacy of antitumor treatment for liver metastases from colorectal cancer.
Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorouracil; Hepatic Artery; Humans; | 1981 |
Chemotherapeutic studies on N-nitrosoacetoxymethyl-methylamine-and 1,2-dimethylhydrazine-induced colonic tumors in rats: monotherapy with 5-fluorouracil, ftorafur, CGP 6809, and CGP 15'720A.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Carcinogens; Colonic Neoplasms; Dimethylhydra | 1982 |
[Anticancer effect of levamisole and tegafur on 1,2-dimethylhydrazine (DMH)-induced colonic cancers in rats].
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Colonic Neoplasms; Dimethylhydrazines; Fluoro | 1982 |
[Clinical trial of UFT in recurrent or advanced cancer].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasm | 1982 |
[Augmentation of chemotherapeutic efficaciousness of UFT by oral l-leucovorin--growth-inhibitory activity of combination against human tumor xenograft].
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols | 1995 |
[Augmentation of chemotherapeutic efficaciousness of UFT by oral l-leucovorin--l-leucovorin factors enhancing cytotoxic activity of 5-fluorouracil].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colonic Neopla | 1995 |
Severe chronic active hepatitis induced by UFTR containing tegafur and uracil.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Chemic | 1995 |
[A case of remarkable response of colon cancer with multiple liver and bone metastasis treated with tegafur and cisplatin].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Colonic N | 1995 |
Effects of preoperative chemotherapy on DNA ploidy patterns, cell cycle, and histological findings in gastric and colonic cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Chemothe | 1994 |
[Antitumor and anticachectic activity of UFT in BALB/c mice bearing colon 26 adenocarcinoma].
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cachexia; Colo | 1994 |
[The concentration of FT in peripheral blood and portal blood after oral, intravenous or rectal administration].
Topics: Administration, Oral; Colonic Neoplasms; Fluorouracil; Humans; Infusions, Intravenous; Liver Neoplas | 1994 |
[Clinical efficacy of cis-diamminedichloroplatinum [II] and 5-fluorouracil (UFT) in advanced cancer of the alimentary tract].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Drug Admi | 1993 |
[A comparison of 5-fluorouracil concentration of 5-fluorouracil drip infusion versus orally UFT in plasma of same patients].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms | 1993 |
Effect of 5-fluorouracil and UFT on experimental liver metastasis model of colorectal cancer using mouse colon 26 cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Combinations; Drug | 1993 |
A pharmacodynamic and pharmacokinetic study of fluoropyrimidines in a nude mouse system and in postoperative patients with gastric cancer.
Topics: Adenocarcinoma; Administration, Oral; Animals; Colonic Neoplasms; Fluorouracil; Gastrectomy; Humans; | 1993 |
[Evaluation of long-term administration of oral anti-cancer agent].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Coloni | 1993 |
[A case of advance colon cancer responding to sequential methotrexate and 5-fluorouracil therapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administrati | 1993 |
Complete response of transverse colon carcinoma to S1, a new chemotherapy agent: report of a case.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colon; Colonic Neoplasms; Humans; Ma | 1995 |
Antitumor activity of 1 M tegafur-0.4 M 5-chloro-2,4-dihydroxypyridine-1 M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell | 1996 |
[Prolongation of survival and antitumor activity of antitumor drugs in murine cancer cachexia model].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cachexia; Colonic Neoplasms; Dinoprostone; | 1996 |
Antitumor activity and low intestinal toxicity of S-1, a new formulation of oral tegafur, in experimental tumor models in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Combinations; Drug Screening Assay | 1997 |
Chemotherapy-induced acral erythema due to Tegafur.
Topics: Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Erythema; Female | 1997 |
Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group.
Topics: Administration, Oral; Aged; Aged, 80 and over; Ambulatory Care; Antidotes; Antimetabolites, Antineop | 1997 |
Inhibitory effects of fluorinated pyrimidines, 5'-DFUR, UFT and T-506, in a model of hepatic metastasis of mouse colon 26 adenocarcinoma-assessment of inhibitory activity and adverse reactions at the maximum tolerated dose.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Body Weight; Colonic Neoplasms; Dose-Response Relati | 1997 |
[Case of acute immune hemolytic anemia developing during fluorouracil administration following surgery of colonic cancer].
Topics: Anemia, Hemolytic, Autoimmune; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Co | 1997 |
Future directions in the adjuvant treatment of colon cancer.
Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms | 1997 |
[Preoperative chemotherapy for advanced colorectal carcinomas--comparison of histological effect between UFT + leucovorin tablet and UFT alone].
Topics: Administration, Oral; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Colonic Neopl | 1998 |
Colon cancer: new drug options improve on 5-FU.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoco | 1998 |
Induction of apoptosis in human tumour xenografts after oral administration of uracil and tegafur to nude mice bearing tumours.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma; Cell Division; Colonic Neoplasms; Ga | 1998 |
Therapeutic effect of 1 M tegafur-0.4 M 5-chloro-2,4-dihydroxypyridine-1 M potassium oxonate (S-1) on liver metastasis of xenotransplanted human colon carcinoma.
Topics: Animals; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Combinations; Humans; Liver Neopla | 1999 |
Experimental postoperative adjuvant chemotherapy by UFT using primary tumor amputation model.
Topics: Amputation, Surgical; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinom | 2000 |
[Combined effect of S-1 and CDDP as a modulator for colon 26 liver metastasis].
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Cisplatin; Colonic Neoplasms; Drug Combinatio | 2000 |
[A case report of unresectable colon cancer that disappeared following pharmacokinetic modulation chemotherapy (PMC)].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug | 2000 |
[Three cases of liver metastasis of colon cancer responding to systemic combination chemotherapy utilizing CPT-11].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptotheci | 2000 |
Phase II study of oral tegafur-uracil and folinic acid as first-line therapy for metastatic colorectal cancer: Taiwan experience.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; C | 2000 |
[Outcomes of home anti-cancer chemotherapy--estimation of hepatic arterial infusion chemotherapy for patients with multiple liver metastases].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Fluorouracil; He | 2000 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
National Surgical Adjuvant Breast and Bowel Project trials in colon cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, A | 2001 |
UFT-induced haemolytic anaemia.
Topics: Aged; Aged, 80 and over; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Colonic | 2001 |
Expression of CYP2A6 in tumor cells augments cellular sensitivity to tegafur.
Topics: Antimetabolites, Antineoplastic; Aryl Hydrocarbon Hydroxylases; Cell Division; Colonic Neoplasms; Co | 2001 |
[Relationship between the anti-metastatic effect of UFT and in vitro chemosensitivity to 5-FU in metastatic tumors from orthotopic implanted colon cancer in nude rats].
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Combinations; Drug Screening Assays, Antitum | 2001 |
gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor.
Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma; Carc | 2001 |
MLL gene rearrangement in acute myelogenous leukemia after exposure to tegafur/uracil.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chromosomes, Human, Pair 11; Chromosomes, | 2002 |
Chemoimmunotherapy of metastatic large bowel cancer: nonspecific stimulation with BCG and levamisole.
Topics: BCG Vaccine; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Levamisole; Lomusti | 1977 |
Phase II clinical trial of ftorafur in 5-fluorouracil-refractory colorectal cancer.
Topics: Adult; Aged; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Re | 1977 |
Iv methyl-CCNU and ftorafur with or without methanol-extracted residue of BCG for metastatic adenocarcinoma of the colon.
Topics: Adenocarcinoma; BCG Vaccine; Colonic Neoplasms; Fluorouracil; Humans; Injections, Intravenous; Leuko | 1977 |
Chemoimmunotherapy with BCG and FT 207 (II).
Topics: BCG Vaccine; Colonic Neoplasms; Fluorouracil; Humans; Rectal Neoplasms; Tegafur | 1978 |
Phase II evaluation of ftorafur in previously untreated colorectal cancer: a Southwest Oncology Group Study.
Topics: Adenocarcinoma; Adult; Aged; Central Nervous System; Colonic Neoplasms; Drug Evaluation; Female; Flu | 1979 |
[Effect of ftorafur and 5-fluorouracil on the chromosomes of human tumor cell cultures].
Topics: Cells, Cultured; Chromosome Deletion; Chromosomes, Human; Colonic Neoplasms; Fluorouracil; Humans; K | 1979 |
Phase I-II study of ftorafur and methyl-CCNU in advanced colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Bone Marrow; Colonic Neoplasms; Digestive System; Drug Evaluation; Drug | 1979 |
[Pharmacokinetic studies on fluorinated pyrimidine in cancer cell and tissue].
Topics: Animals; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Esophageal Neoplasms; Female; Fluorouracil; Gl | 1992 |
[Pharmacokinetic study of tegafur in the hepatic tissue obtained from the patients with liver cancer].
Topics: Aged; Colonic Neoplasms; Fluorouracil; Humans; Liver; Liver Neoplasms; Middle Aged; Stomach Neoplasm | 1992 |
[A case of colon cancer with severe anal bleeding caused in a preoperative chemotherapy].
Topics: Adenocarcinoma; Administration, Oral; Adult; Anal Canal; Antineoplastic Combined Chemotherapy Protoc | 1991 |
[Antitumor activity of T-506, a novel synthetic FUDR derivative, on murine colon cancer and its hepatic metastasis].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; F | 1991 |
[Combination chemotherapy with orally administered UFT and leucovorin (LV)].
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemot | 1991 |
[Effect of UFT by oral administration using a murine hepatic metastasis model].
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Hu | 1991 |
[Study of pre-operative chemotherapeutic methods for colonic cancer--the concentration in blood and tissues after pre-operative administration of UFT].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms | 1991 |
[Treatment with UFT as surgical adjuvant chemotherapy in carcinoma of large intestine. Cooperative Study Group of Surgical Adjuvant Chemotherapy for Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Hum | 1990 |
[Analysis of the mechanism of increased antitumor activity of UFT after combined treatment with CDDP].
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasm | 1990 |
[Experimental study of the effect of combined treatment of UFT with CDDP on human solid tumor-xenografts in nude mice].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cisplatin; | 1990 |
[Tissue UFT distribution and histological changes following UFT administration in metastatic liver cancer cases].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Human | 1990 |
[Combination chemotherapy of UFT with adriamycin (ADM) and cisplatin (CDDP) for advanced gastrointestinal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Cisplatin; Col | 1990 |
[Effects of hyperthermochemotherapy on activities of DNA-synthesizing enzymes in 1, 2-dimethylhydrazine (DMH)-induced colon carcinomas in rats].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Colo | 1990 |
[Myelodysplastic syndrome (RAEB-T) occurring after adjuvant chemotherapy for colon and rectum cancers].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Colonic Neoplasms; Cytarabine; DN | 1990 |
[Study of tissue drug concentration of fluorinated pyrimidine anticancer drugs--comparison of 5'DFUR and UFT].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colon; Colonic Neoplasms; Dru | 1990 |
The effect of UFTM therapy on primary and metastatic colon cancer from the same human xenotransplanted into nude mice.
Topics: Adenocarcinoma, Mucinous; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Colo | 1990 |
[An autopsy study of immunoblastic lymphadenopathy (IBL)-like T-cell lymphoma in a patient previously treated with chemotherapy in colon cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; | 1989 |
[Influence of OK-432 on intratumor 5-fluorouracil concentration in cases given UFT].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biological Products; Biotransformation; Colonic Neop | 1989 |
[Anti-tumor effect of fluoropyrimidines on human tumor cell lines transplanted in nude mice with CCl4-induced liver dysfunction].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carbon Tetrachloride; Cell Line; Colonic Ne | 1989 |
[Combination chemotherapy with 3 or 4 drugs on human breast and gastrointestinal cancer xenografts in nude mice (II)].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Colonic Neopla | 1987 |
[Comparative studies on the antitumor activity of the fluorinated pyrimidines 5'-DFUR, tegafur, UFT and FUra on various murine tumors].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Floxuridine; Fluorouraci | 1988 |
[Effects of preoperative administration of UFT in gastrointestinal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Humans; Kine | 1986 |
[Combination cancer chemotherapy of human gastric and colon carcinomas in nude mice--sequential cancer chemotherapy involving mitomycin C and tegafur].
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; DNA, Neo | 1986 |
[Study of chemotherapy in the field of internal medicine--clinical experience with SF-SP].
Topics: Administration, Oral; Aged; Breast Neoplasms; Colonic Neoplasms; Delayed-Action Preparations; Drug A | 1986 |
[5-FU concentration in the blood and tissue of patients with gastric and colorectal cancer after administration of UFT or tegafur].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Male; Rats | 1986 |
[In vivo chemosensitivity test for UFT and FT-207. I--Subrenal capsule assay].
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Colonic Neopla | 1987 |
[Chemosensitivity testing for 5-FU and 5-FU derivatives using subrenal capsule assay].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colony-Forming Units Assay; Fluor | 1987 |
Thymidylate synthetase and thymidine kinase activities in DMH-induced colon carcinomas in rats and effects of UFT.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Combined Chemotherapy Protocols; Colon; Colonic Neopl | 1986 |
[In vivo chemosensitivity test for UFT and FT-207. II. Chemosensitivity test on human tumor xenografts transplanted in nude mice].
Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Animals; Antineoplastic Combined Chemotherapy Protocols; | 1987 |
[Effect of combination of UFT and MMC (UFT-M therapy) on human colonic cancer xenotransplanted into nude mice].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Colonic Neoplasms; Drug Admi | 1987 |
[Comparative clinical studies of colorectal tumor tissue and normal tissue following arterial injection of tegafur].
Topics: Adult; Aged; Colonic Neoplasms; Female; Humans; Injections, Intra-Arterial; Male; Middle Aged; Recta | 1987 |
[Combination chemotherapy of UFT with adriamycin in advanced gastrointestinal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Colonic Neopla | 1987 |
[The effect of tegafur suppository and glutathione in patients with gastric and colonic cancer with special reference to the histopathological anticancer effect].
Topics: Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Glutathione; Humans; Stomach Neoplasms; | 1987 |
[The effect of UFT on lymphocyte subsets and lymphocyte response to PHA].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Humans; Immunocompetence; Lymphoc | 1987 |
[The effect of UFT on thymidine kinase and thymidylate synthetase activities and autoradiograph in DMH-induced colon cancer in rat].
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Combined Chemotherapy Protocols; Autoradiography; Col | 1987 |
[Human colorectal carcinoma is more sensitive to HCFU than 5-FU and tegafur in in vitro and in vivo drug sensitivity tests].
Topics: Animals; Colonic Neoplasms; Fluorouracil; Humans; Mice; Rectal Neoplasms; Subrenal Capsule Assay; Te | 1988 |
[A case of colon cancer with pulmonary metastasis treated effectively by uracil futraful].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Humans; L | 1988 |
[Effects of SSM (purified polysaccharides from human tubercle bacillus, maruyama vaccine) and UFT (a combination of tegafur and uracil) on DNA-synthesizing enzyme activities in 1,2-dimethylhydrazine (DMH)-induced rat colon carcinomas].
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol | 1987 |
[A case of colorectal cancer showing complete response to UFT].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined M | 1988 |
Combined effects of UFT with other anticancer agents using in vivo chemosensitivity tests.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Transformed; Colonic Neoplasms; | 1988 |
[Combined effects of interferon alpha-A/D with fluoropyrimidine derivatives in the subrenal capsule assay].
Topics: Animals; Colonic Neoplasms; Drug Synergism; Fluorouracil; Interferon Type I; Male; Mice; Mice, Nude; | 1988 |
[The serum and tissue concentrations of tegafur, 5-fluorouracil and uracil in patients with gastric and colorectal cancers after oral administration of UFT].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouraci | 1988 |
[Effect of UFTM therapy on primary and metastatic colon cancer of human xenotransplanted in nude mice].
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Hu | 1988 |
A mechanism for the potentiation of the cytotoxic effects of antimetabolites drugs (FT-207, 5FU) by hyperthermia.
Topics: Cell Line; Cell Survival; Colonic Neoplasms; Combined Modality Therapy; Cytosol; Fluorouracil; Hot T | 1988 |
Long-term survivors of colorectal cancer with unresectable hepatic metastases.
Topics: Administration, Oral; Aged; Carcinoembryonic Antigen; Colonic Neoplasms; Female; Fluorouracil; Human | 1985 |
Longer survival and fewer metastases by levamisole and tegafur in 1, 2-dimethylhydrazine-induced murine colonic cancers.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Colonic | 1985 |