tegafur has been researched along with Brain Neoplasms in 36 studies
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Controlled, prospective, randomized studies were performed to evaluate the effects of 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3- (2-chloroethyl)-3-nitrosourea hydrochloride (ACNU) and ACNU plus tegafur as additions to radiotherapy for the treatment of malignant gliomas." | 9.05 | [Evaluation of ACNU alone and combined with tegafur as additions to radiotherapy of the treatment of malignant gliomas--a cooperative clinical trial]. ( Abe, H; Kitamura, K; Matsutani, M; Miwa, T; Nomura, K; Suzuki, J; Takakura, K; Takeuchi, K; Tanaka, R; Ushio, Y, 1985) |
| " Conventional, external radiotherapy (180-200 cGy/5 fractions/week) using 60Co or a 10 MV linear accelerator was given in conjunction with chemotherapy of nimustine hydrochloride (ACNU) and tegafur (FT-207) in eight patients with gliomas." | 7.67 | [Radiochemotherapy-related changes in the brain parenchyma of glioma patients evaluated repeatedly by C15O2, C15O, 15O2, and 18F-fluorodeoxyglucose (FDG) PET]. ( Kowada, M; Mineura, K; Ogawa, T; Sasajima, T; Shishido, F; Suda, Y; Uemura, K, 1989) |
| "Controlled, prospective, randomized studies were performed to evaluate the effects of 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3- (2-chloroethyl)-3-nitrosourea hydrochloride (ACNU) and ACNU plus tegafur as additions to radiotherapy for the treatment of malignant gliomas." | 5.05 | [Evaluation of ACNU alone and combined with tegafur as additions to radiotherapy of the treatment of malignant gliomas--a cooperative clinical trial]. ( Abe, H; Kitamura, K; Matsutani, M; Miwa, T; Nomura, K; Suzuki, J; Takakura, K; Takeuchi, K; Tanaka, R; Ushio, Y, 1985) |
| " Conventional, external radiotherapy (180-200 cGy/5 fractions/week) using 60Co or a 10 MV linear accelerator was given in conjunction with chemotherapy of nimustine hydrochloride (ACNU) and tegafur (FT-207) in eight patients with gliomas." | 3.67 | [Radiochemotherapy-related changes in the brain parenchyma of glioma patients evaluated repeatedly by C15O2, C15O, 15O2, and 18F-fluorodeoxyglucose (FDG) PET]. ( Kowada, M; Mineura, K; Ogawa, T; Sasajima, T; Shishido, F; Suda, Y; Uemura, K, 1989) |
| "Haemocirculatory and metabolic changes in seemingly normal brain tissue following radiochemotherapy including nimustine hydrochloride (ACNU) and tegafur (FT) were analyzed using oxygen-15 and fluorine-18 positron emission tomography (PET) in seven patients with gliomas." | 3.67 | Early and late stage positron emission tomography (PET) studies on the haemocirculation and metabolism of seemingly normal brain tissue in patients with gliomas following radiochemotherapy. ( Kowada, M; Mineura, K; Ogawa, T; Shishido, F; Suda, Y; Uemura, K; Yasuda, T, 1988) |
| "He died of brain metastases." | 2.72 | [A case of adenocarcinoma of the lung significantly responding to TS-1 plus cisplatin combination chemotherapy]. ( Asou, H; Ichinose, Y; Maruyama, R; Okamoto, T; Suemitsu, R; Wataya, H, 2006) |
| "Generally, malignant brain tumors have a decreased blood flow that results in increased resistance to radiation and reduced delivery of chemotherapeutic agents and oxygen." | 2.71 | Increased locoregional blood flow in brain tumors after cervical spinal cord stimulation. ( Caramés, MA; Catalá, L; Clavo, B; Hernández, MA; Lloret, M; Morera, J; Panero, F; Robaina, F; Ruiz-Egea, E; Valcárcel, B, 2003) |
| "He was diagnosed with advanced gastric cancer with multiple liver metastases." | 1.42 | [Multidisciplinary Therapy for Advanced Gastric Cancer with Liver and Brain Metastases]. ( Ako, E; Hirakawa, T; Kametani, N; Kanehara, I; Kato, Y; Komoto, M; Nakazawa, K; Nishimura, S; Taenaka, N; Tanaka, R; Yamada, N; Yamagata, S, 2015) |
| "He then underwent excision of the brain metastases and consecutive radiation by X-knife." | 1.32 | [A case of liver metastases from gastric cancer successfully treated with induced hypertensive chemotherapy]. ( Arai, K; Iwasaki, Y; Katayanagi, S; Matsumoto, H; Miyamoto, H; Takahashi, K; Yamaguchi, T, 2003) |
| "He was diagnosed as having right renal cell carcinoma which had metastasized to the lung." | 1.28 | [A case of recurrence of a metastatic brain tumor which disappeared due to chemotherapy only]. ( Kayama, T; Ogawa, A; Sakurai, Y; Sato, K; Wada, T, 1990) |
| "Tamoxifen and UFT were administered as chemoendocrine therapy." | 1.28 | [A case of brain metastasis from breast cancer responding to chemoendocrine therapy]. ( Abe, R; Honda, K; Kanazawa, M; Nomizu, T; Tsuchiya, A; Watanabe, F; Yamaki, Y, 1990) |
| "Nineteen patients with brain tumors were orally administered 300 mg of UFT (a combination of FT and uracil with a molar ratio being 1:4) before operation and the concentrations of FT, 5-FU and Uracil in tumors and serum were measured by chemical assay." | 1.27 | [5-FU concentration in brain tumors after co-administration of FT and uracil]. ( Matsumoto, S; Nogaki, H; Tamaki, N; Taomoto, K, 1983) |
| "Thirteen patients with metastatic brain tumors were treated with two different chemotherapy regimens." | 1.27 | [The effect of combined chemotherapy with UFT, cis-platinum and aclarubicin in metastatic brain tumors]. ( Kida, Y; Kobayashi, T; Tanaka, T, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (50.00) | 18.7374 |
| 1990's | 6 (16.67) | 18.2507 |
| 2000's | 7 (19.44) | 29.6817 |
| 2010's | 5 (13.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, T | 1 |
| Liu, C | 1 |
| Li, Q | 1 |
| Xiong, J | 1 |
| Ma, Y | 1 |
| Wu, G | 1 |
| Zhao, Y | 1 |
| Akiyama, N | 1 |
| Karayama, M | 1 |
| Inui, N | 1 |
| Yasui, H | 1 |
| Hozumi, H | 1 |
| Suzuki, Y | 1 |
| Furuhashi, K | 1 |
| Fujisawa, T | 1 |
| Enomoto, N | 1 |
| Nakamura, Y | 2 |
| Inami, N | 1 |
| Matsuura, S | 1 |
| Kaida, Y | 1 |
| Uto, T | 1 |
| Matsui, T | 1 |
| Asada, K | 1 |
| Matsuda, H | 1 |
| Fujii, M | 1 |
| Toyoshima, M | 1 |
| Suda, T | 1 |
| Nakazawa, K | 1 |
| Tanaka, R | 2 |
| Kametani, N | 1 |
| Hirakawa, T | 1 |
| Kato, Y | 1 |
| Komoto, M | 1 |
| Yamagata, S | 1 |
| Kanehara, I | 1 |
| Ako, E | 1 |
| Yamada, N | 1 |
| Nishimura, S | 1 |
| Taenaka, N | 1 |
| Hizawa, K | 1 |
| Nagata, Y | 1 |
| Taniguchi, M | 1 |
| Nakamori, M | 1 |
| Matsumoto, T | 1 |
| Iida, M | 1 |
| Matsumura, T | 1 |
| Ohzato, H | 1 |
| Yamamoto, T | 1 |
| Ota, K | 2 |
| Mabuchi, E | 1 |
| Miwa, H | 1 |
| Ikeda, H | 2 |
| Fukunaga, M | 1 |
| Furukawa, H | 1 |
| Yabe, N | 1 |
| Murai, S | 1 |
| Akatsu, T | 1 |
| Shoji, T | 1 |
| Shimizu, H | 1 |
| Fukushima, H | 1 |
| Mitsugi, Y | 1 |
| Ishida, T | 1 |
| Amemiya, T | 1 |
| Hasegawa, H | 2 |
| Kitagawa, Y | 1 |
| Kagawa, K | 1 |
| Kawakami, Y | 1 |
| Honda, Y | 1 |
| Nakahara, T | 1 |
| Tanaka, M | 1 |
| Naeshiro, N | 1 |
| Miyaki, D | 1 |
| Nagaoki, Y | 1 |
| Kawaoka, T | 1 |
| Takaki, S | 1 |
| Hiramatsu, A | 1 |
| Waki, K | 1 |
| Hyogo, H | 1 |
| Aikata, H | 1 |
| Takahashi, S | 1 |
| Arihiro, K | 1 |
| Sanetou, H | 1 |
| Chayama, K | 1 |
| Clavo, B | 1 |
| Robaina, F | 1 |
| Catalá, L | 1 |
| Valcárcel, B | 1 |
| Morera, J | 1 |
| Caramés, MA | 1 |
| Ruiz-Egea, E | 1 |
| Panero, F | 1 |
| Lloret, M | 1 |
| Hernández, MA | 1 |
| Katayanagi, S | 1 |
| Arai, K | 1 |
| Iwasaki, Y | 1 |
| Takahashi, K | 1 |
| Yamaguchi, T | 1 |
| Matsumoto, H | 1 |
| Miyamoto, H | 1 |
| Wataya, H | 1 |
| Asou, H | 1 |
| Maruyama, R | 1 |
| Okamoto, T | 1 |
| Suemitsu, R | 1 |
| Ichinose, Y | 1 |
| Saeki, H | 1 |
| Anegawa, G | 1 |
| Masuda, T | 1 |
| Ohta, R | 1 |
| Honda, M | 1 |
| Kai, T | 1 |
| Kaneko, S | 1 |
| Anai, H | 1 |
| Yokoyama, S | 1 |
| Tsuchida, T | 1 |
| Watanabe, E | 1 |
| Nakayama, H | 1 |
| Sasaki, A | 1 |
| Nakamura, S | 1 |
| Sasaki, M | 1 |
| Fujiwara, T | 1 |
| Nemoto, S | 1 |
| Fujiwara, K | 1 |
| Yanagibashi, K | 1 |
| Hayakawa, I | 1 |
| Nomura, K | 2 |
| Harada, K | 2 |
| Okamoto, H | 2 |
| Kiya, K | 2 |
| Fujioka, Y | 2 |
| Uozumi, T | 2 |
| Kodama, Y | 1 |
| Nogaki, H | 1 |
| Taomoto, K | 1 |
| Tamaki, N | 1 |
| Matsumoto, S | 1 |
| Sueyoshi, K | 1 |
| Majima, H | 1 |
| Matsuura, H | 1 |
| Nakazawa, S | 1 |
| Hirota, F | 1 |
| Hosaka, K | 1 |
| Funahashi, K | 1 |
| Oota, M | 1 |
| Ikeda, A | 1 |
| Oobayashi, Y | 1 |
| Fujii, S | 1 |
| Inada, Y | 1 |
| Murai, M | 1 |
| Ishihama, H | 1 |
| Mori, T | 3 |
| Fukawa, O | 1 |
| Sato, T | 1 |
| Hori, S | 1 |
| Apinis, TA | 1 |
| Zilbere, AM | 1 |
| Meĭrena, DV | 1 |
| Gilev, AP | 1 |
| Zhuk, RA | 1 |
| Ushio, Y | 2 |
| Arita, N | 1 |
| Hayakawa, T | 1 |
| Mogami, H | 1 |
| Bitoh, S | 1 |
| Oku, Y | 1 |
| Kanai, N | 1 |
| Kanoh, M | 1 |
| Tomura, N | 1 |
| Kato, T | 2 |
| Ogawa, T | 3 |
| Kanno, I | 1 |
| Shishido, F | 3 |
| Inugami, A | 1 |
| Fujita, H | 1 |
| Higano, S | 1 |
| Murakami, M | 1 |
| Uemura, K | 3 |
| Sato, K | 1 |
| Kayama, T | 1 |
| Sakurai, Y | 1 |
| Ogawa, A | 2 |
| Wada, T | 4 |
| Wakisaka, S | 2 |
| Shimauchi, M | 2 |
| Kaji, Y | 2 |
| Nonaka, A | 2 |
| Kinoshita, K | 2 |
| Nomizu, T | 1 |
| Watanabe, F | 1 |
| Honda, K | 1 |
| Kanazawa, M | 1 |
| Yamaki, Y | 1 |
| Tsuchiya, A | 1 |
| Abe, R | 1 |
| Mineura, K | 2 |
| Suda, Y | 2 |
| Sasajima, T | 1 |
| Kowada, M | 2 |
| Abe, H | 1 |
| Suzuki, J | 4 |
| Kitamura, K | 1 |
| Miwa, T | 1 |
| Matsutani, M | 1 |
| Takeuchi, K | 1 |
| Takakura, K | 1 |
| Shingai, J | 2 |
| Namiki, T | 1 |
| Kitahara, M | 2 |
| Katakura, R | 2 |
| Kanno, M | 1 |
| Niizuma, H | 2 |
| Yoshimoto, T | 2 |
| Tanaka, T | 1 |
| Kobayashi, T | 1 |
| Kida, Y | 1 |
| Maruoka, N | 1 |
| Moriyama, T | 1 |
| Oyama, H | 1 |
| Goya, T | 1 |
| Kodama, T | 1 |
| Yasuda, T | 1 |
| Kojima, Y | 1 |
| Watanabe, T | 1 |
| Sanada, T | 1 |
| Hiramatsu, Y | 1 |
| Nakane, Y | 1 |
| Yamamura, M | 1 |
| Hioki, K | 1 |
| Yamamoto, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Positron Emission Tomography With Fluoro-misonidazole (PET-FMISO) in High Grade Gliomas: Assessment of Tumor Hypoxia and Effect of Spinal Cord Stimulation[NCT01868906] | Phase 2 | 6 participants (Actual) | Interventional | 2013-06-30 | Terminated (stopped due to Isotope (FMISO) production is no longer available in our country.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tegafur and Brain Neoplasms
| Article | Year |
|---|---|
[A case of postoperative brain metastasis originated from pancreatic cancer which was successfully treated by resection and postoperative irradiation].
Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Carcinoma, Ductal; Combined Modality Therapy; Deox | 2009 |
5 trials available for tegafur and Brain Neoplasms
| Article | Year |
|---|---|
Switch maintenance therapy with S-1 after induction therapy with carboplatin and nanoparticle albumin-bound paclitaxel in advanced lung squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Albumins; Antineoplastic Combined Chemotherapy Protocols; Bone Neopl | 2019 |
Increased locoregional blood flow in brain tumors after cervical spinal cord stimulation.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blood Flow Velocity; Brain Neop | 2003 |
[A case of adenocarcinoma of the lung significantly responding to TS-1 plus cisplatin combination chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Dr | 2006 |
Chemotherapy of brain metastases from lung carcinoma: a controlled randomized study.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Carcinom | 1991 |
[Evaluation of ACNU alone and combined with tegafur as additions to radiotherapy of the treatment of malignant gliomas--a cooperative clinical trial].
Topics: Adolescent; Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Cli | 1985 |
30 other studies available for tegafur and Brain Neoplasms
| Article | Year |
|---|---|
Apatinib + CPT-11 + S-1 for treatment of refractory brain metastases in patient with triple-negative breast cancer: Case report and literature review.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Edema; Brain Neoplasms; Camptothecin; D | 2018 |
[Multidisciplinary Therapy for Advanced Gastric Cancer with Liver and Brain Metastases].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined Modality | 2015 |
[Case of gastric cancer with isolated brain metastasis successfully managed by gamma knife radiotherapy and chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined | 2008 |
[A case of advanced gastric cancer resistant to S-1 successfully treated with weekly administration of paclitaxel].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Carcinoma; Drug | 2010 |
[A case of advanced hepatocellular carcinoma with lung, brain and lymph node metastases recurred 8 years after hepatectomy successfully treated by operation, radiation and systemic chemotherapy using S-1/CDDP].
Topics: Adult; Antimetabolites, Antineoplastic; Brain Neoplasms; Carcinoma, Hepatocellular; Combined Modalit | 2012 |
[A case of liver metastases from gastric cancer successfully treated with induced hypertensive chemotherapy].
Topics: Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Brain Neoplasm | 2003 |
[A case of inoperable gastric small cell carcinoma effectively treated by chemotherapy and radiotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Carcinoma, Smal | 2006 |
[FAR therapy in brain tumors--FT207-vitamin A-Radiation therapy (author's transl)].
Topics: Adolescent; Adult; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Drug Therapy, Combination; | 1980 |
[Pharmacokinetics study of UFT in malignant brain tumor patients].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; | 1983 |
[5-FU concentration in brain tumors after co-administration of FT and uracil].
Topics: Brain Neoplasms; Drug Therapy, Combination; Fluorouracil; Glioblastoma; Humans; Meningeal Neoplasms; | 1983 |
[Cerebrospinal fluid distributions of systemically administered fluorinated pyrimidines].
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Ependymoma; Female; Fluorouracil; Glioblastoma; | 1983 |
[FT-207 and 5-FU concentrations in brain tumor tissues, plasma and CSF after administration of FT-207 suppository].
Topics: Brain; Brain Neoplasms; Fluorouracil; Humans; Rectum; Suppositories; Tegafur | 1984 |
Pharmacodynamics of co-administration of uracil and 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) for malignant brain tumors.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neo | 1983 |
[Effective treatment of AFP-producing lung cancer with UFT].
Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; alpha-Fetoproteins; Antineoplastic Ag | 1999 |
[A case of breast cancer with multiple metastases effectively treated with long-term administration of docetaxel, aclarubicin and UFT].
Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Breast | 2001 |
[Regression of a recurrent malignant glioma by combined chemoradiotherapy utilizing carboquone, FT-207 and telecobalt--report of a case (author's transl)].
Topics: Azirines; Brain Neoplasms; Carbazilquinone; Cobalt Radioisotopes; Drug Therapy, Combination; Fluorou | 1977 |
[Clinical pharmacokinetics of 2-C14-ftorafur in patients with astrocytoma].
Topics: Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Cerebral Cortex; Fluorouracil; Humans; Injections | 1976 |
[The changes of cerebral blood flow and metabolism of normal brain tissue after surgery, radiation, and chemotherapy in brain tumor patients: evaluated by position emission tomography].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Cerebrova | 1990 |
[A case of recurrence of a metastatic brain tumor which disappeared due to chemotherapy only].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Renal Cell; Humans; Kidn | 1990 |
Acute phenytoin intoxication associated with the antineoplastic agent UFT.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; D | 1990 |
[A case of brain metastasis from breast cancer responding to chemoendocrine therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Carcinoma, | 1990 |
[Radiochemotherapy-related changes in the brain parenchyma of glioma patients evaluated repeatedly by C15O2, C15O, 15O2, and 18F-fluorodeoxyglucose (FDG) PET].
Topics: Adolescent; Adult; Antineoplastic Agents; Brain; Brain Neoplasms; Carbon Radioisotopes; Cerebrovascu | 1989 |
[Effects of derivatives of Ara-C, 5-fluorouracil and nitrosourea against intracerebral implanted L1210 leukemia].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; | 1987 |
[A case of adult respiratory distress syndrome (ARDS) induced by radio-chemotherapy (RAFP therapy) of brain metastasis of stomach cancer].
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Brain Neoplasms; Humans; Male; Nimustine; Nitrosourea C | 1986 |
[Results of combined radiochemotherapy of intracranial ependymoma].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebral Ventric | 1987 |
[The effect of combined chemotherapy with UFT, cis-platinum and aclarubicin in metastatic brain tumors].
Topics: Aclarubicin; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neop | 1987 |
[Results of supratentorial low-grade astrocytoma--effects of combined radiochemotherapy].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cer | 1987 |
[AUFRAP therapy: combined modality treatment of malignant gliomas with intraarterial infusion of ACNU].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carotid Artery, Internal; Co | 1988 |
Early and late stage positron emission tomography (PET) studies on the haemocirculation and metabolism of seemingly normal brain tissue in patients with gliomas following radiochemotherapy.
Topics: Adolescent; Adult; Brain; Brain Neoplasms; Cerebrovascular Circulation; Child; Combined Modality The | 1988 |
[A case report of brain metastasis due to an advanced gastric cancer].
Topics: Brain Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Stomach Neoplasms | 1988 |