Page last updated: 2024-11-04

tegafur and Blood Diseases

tegafur has been researched along with Blood Diseases in 18 studies

Research Excerpts

ExcerptRelevanceReference
"Here, we reported an interim analysis of feasibility and safety in the first 10 cases of 30 cases in a phase II trial of intravenous and intraperitoneal paclitaxel combined with S-1 for gemcitabine-refractory pancreatic cancer with malignant ascites."9.19Intravenous and intraperitoneal paclitaxel with S-1 for refractory pancreatic cancer with malignant ascites: an interim analysis. ( Hamada, T; Hirano, K; Ijichi, H; Isayama, H; Ishigami, H; Kawakubo, K; Kitayama, J; Kogure, H; Koike, K; Miyabayashi, K; Mizuno, S; Mohri, D; Nakai, Y; Sasahira, N; Sasaki, T; Tada, M; Takahara, N; Tateishi, K; Uchino, R; Watanabe, T; Yamaguchi, H; Yamamoto, N; Yamashita, H, 2014)
"Here, we reported an interim analysis of feasibility and safety in the first 10 cases of 30 cases in a phase II trial of intravenous and intraperitoneal paclitaxel combined with S-1 for gemcitabine-refractory pancreatic cancer with malignant ascites."5.19Intravenous and intraperitoneal paclitaxel with S-1 for refractory pancreatic cancer with malignant ascites: an interim analysis. ( Hamada, T; Hirano, K; Ijichi, H; Isayama, H; Ishigami, H; Kawakubo, K; Kitayama, J; Kogure, H; Koike, K; Miyabayashi, K; Mizuno, S; Mohri, D; Nakai, Y; Sasahira, N; Sasaki, T; Tada, M; Takahara, N; Tateishi, K; Uchino, R; Watanabe, T; Yamaguchi, H; Yamamoto, N; Yamashita, H, 2014)
"To test the efficacy and safety of pharmacokinetic modulating chemotherapy combined with cisplatin (PMC-cisplatin) as induction chemotherapy (ICT) before definitive treatment in patients with respectable locally advanced head and neck squamous cell carcinoma (HNSCC)."2.73Effectiveness of pharmacokinetic modulating chemotherapy combined with cisplatin as induction chemotherapy in resectable locally advanced head and neck cancer: phase II study. ( Chang, PM; Chang, SY; Chen, PM; Chu, PY; Huang, JL; Tai, SK; Tsai, TL; Wang, LW; Wang, YF; Yang, MH, 2008)
"One patient with colorectal cancer experienced a partial response and 9 patients with non-small cell lung, colorectal and gastro-oesophageal junction carcinomas had disease stabilisation lasting 4-26 (median 6) cycles."2.71Phase I trial of UFT/leucovorin and irinotecan in patients with advanced cancer. ( Algazy, K; Giantonio, B; Hahn, S; Haller, DG; O'Dwyer, PJ; Redlinger, M; Stevenson, JP; Sun, W; Thorn, C; Vaughn, D; Veronese, ML; Whitehead, AS, 2004)
" Therapy was therefore designed with an oral drug daily given in combination with RT in order to determine the efficacy and toxicity."2.71[Radiotherapy in combination with low-dose chemotherapy in locally advanced head and neck cancer]. ( Molnár, J; Nagy, B; Paczona, R; Rovó, L; Thurzó, L, 2004)
" The most appropriate dosing option appeared to be 400 mg x m(-2) per day of oral UFT for 14 consecutive days with 900 mg x m(-2) gemcitabine on days 8 and 15."2.70A phase I study of combination chemotherapy with gemcitabine and oral UFT for advanced non-small cell lung cancer. ( Asoh, H; Ichinose, Y; Semba, H; Seto, T; Yamamoto, H; Yoh, K, 2002)
" We aimed to assess the clinical efficacy and safety of S-1 combined with paclitaxel (PTX) for AGC by performing a systematic review and meta-analysis of the published studies."2.61S-1 combined with paclitaxel may benefit advanced gastric cancer: Evidence from a systematic review and meta-analysis. ( Bian, NN; Min, GT; Wang, YH, 2019)
" Severe adverse events were observed in 22 patients (91."1.42Feasibility and toxicity of adjuvant chemotherapy using S-1 granules for local advanced squamous cell carcinoma of the head and neck. ( Honda, K; Ishikawa, K; Sato, T; Suzuki, S; Yamazaki, K, 2015)
" Five patients showed grade 3 and 4 adverse reactions, all hematological."1.35Safety and efficacy of S-1 chemotherapy in recurrent/metastatic head and neck cancer. ( Ishikawa, K; Suzuki, S, 2009)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (50.00)29.6817
2010's9 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bian, NN1
Wang, YH1
Min, GT1
Takahara, N1
Isayama, H1
Nakai, Y1
Sasaki, T1
Ishigami, H1
Yamashita, H1
Yamaguchi, H1
Hamada, T1
Uchino, R1
Mizuno, S1
Miyabayashi, K1
Mohri, D1
Kawakubo, K1
Kogure, H1
Yamamoto, N1
Sasahira, N1
Hirano, K1
Ijichi, H1
Tateishi, K1
Tada, M1
Kitayama, J1
Watanabe, T1
Koike, K1
Suzuki, S3
Honda, K1
Sato, T1
Yamazaki, K1
Ishikawa, K2
Meulendijks, D1
Henricks, LM1
Sonke, GS1
Deenen, MJ1
Froehlich, TK1
Amstutz, U1
Largiadèr, CR1
Jennings, BA1
Marinaki, AM1
Sanderson, JD1
Kleibl, Z1
Kleiblova, P1
Schwab, M1
Zanger, UM1
Palles, C1
Tomlinson, I1
Gross, E1
van Kuilenburg, AB1
Punt, CJ1
Koopman, M1
Beijnen, JH1
Cats, A1
Schellens, JH1
Soh, J1
Okumura, N1
Nakata, M1
Nakamura, H1
Fukuda, M1
Kataoka, M1
Kajiwara, S1
Sano, Y1
Aoe, M1
Kataoka, K1
Hotta, K1
Matsuo, K1
Toyooka, S1
Date, H1
Kobayashi, S1
Ueno, M1
Hara, H1
Irie, K1
Goda, Y1
Moriya, S1
Tezuka, S1
Tanaka, M1
Okusaka, T1
Ohkawa, S1
Morimoto, M1
Choi, IS1
Lee, KW1
Kim, KH1
Kim, YJ1
Kim, JH1
Lee, JS1
Sunaga, T1
Harada, N1
Hayashi, T1
Suzuki, M1
Shiroyama, T1
Komuta, K1
Imamura, F1
Hirashima, T1
Kijima, T1
Tachibana, I1
Kawase, I1
Veronese, ML1
Stevenson, JP1
Sun, W1
Redlinger, M1
Algazy, K1
Giantonio, B1
Hahn, S1
Vaughn, D1
Thorn, C1
Whitehead, AS1
Haller, DG1
O'Dwyer, PJ1
Nagy, B1
Molnár, J1
Rovó, L1
Paczona, R1
Thurzó, L1
Kim, SJ1
Seo, HY1
Choi, JG1
Sul, HR1
Sung, HJ1
Park, KH1
Choi, IK1
Oh, SC1
Yoon, SY1
Seo, JH1
Choi, CW1
Kim, BS1
Shin, SW1
Kim, YH1
Kim, JS1
Chen, YM1
Perng, RP1
Tsai, CM1
Whang-Peng, J1
Kaira, K1
Sunaga, N1
Yanagitani, N1
Imai, H1
Utsugi, M1
Shimizu, Y1
Iijima, H1
Tomizawa, Y1
Hisada, T1
Ishizuka, T1
Saito, R1
Mori, M1
Chang, PM1
Chen, PM1
Chu, PY1
Wang, LW1
Tai, SK1
Tsai, TL1
Huang, JL1
Wang, YF1
Chang, SY1
Yang, MH1
Vestermark, LW1
Jacobsen, A1
Qvortrup, C1
Hansen, F1
Bisgaard, C1
Baatrup, G1
Rasmussen, P1
Pfeiffer, P1
Seto, T1
Yoh, K1
Asoh, H1
Yamamoto, H1
Semba, H1
Ichinose, Y1

Reviews

2 reviews available for tegafur and Blood Diseases

ArticleYear
S-1 combined with paclitaxel may benefit advanced gastric cancer: Evidence from a systematic review and meta-analysis.
    International journal of surgery (London, England), 2019, Volume: 62

    Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Hematologic Diseases; Humans; Oxo

2019
Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data.
    The Lancet. Oncology, 2015, Volume: 16, Issue:16

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Gas

2015

Trials

13 trials available for tegafur and Blood Diseases

ArticleYear
Intravenous and intraperitoneal paclitaxel with S-1 for refractory pancreatic cancer with malignant ascites: an interim analysis.
    Journal of gastrointestinal cancer, 2014, Volume: 45, Issue:3

    Topics: Adenocarcinoma; Aged; Alopecia; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap

2014
Randomized feasibility study of S-1 for adjuvant chemotherapy in completely resected Stage IA non-small-cell lung cancer: results of the Setouchi Lung Cancer Group Study 0701.
    Japanese journal of clinical oncology, 2016, Volume: 46, Issue:8

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols

2016
Unexpected Side Effects of a High S-1 Dose: Subanalysis of a Phase III Trial Comparing Gemcitabine, S-1 and Combinatorial Treatments for Advanced Pancreatic Cancer.
    Oncology, 2016, Volume: 91, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenosquamous; Deox

2016
Three-weekly S-1 plus cisplatin chemotherapy as first-line treatment for advanced gastric cancer.
    Medical oncology (Northwood, London, England), 2010, Volume: 27, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease-Free

2010
Phase II study of S-1 monotherapy in platinum-refractory, advanced non-small cell lung cancer.
    Lung cancer (Amsterdam, Netherlands), 2011, Volume: 74, Issue:1

    Topics: Administration, Oral; Aged; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free Surviv

2011
Phase I trial of UFT/leucovorin and irinotecan in patients with advanced cancer.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Dos

2004
[Radiotherapy in combination with low-dose chemotherapy in locally advanced head and neck cancer].
    Magyar onkologia, 2004, Volume: 48, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy,

2004
Phase II study with a combination of epirubicin, cisplatin, UFT, and leucovorin in advanced hepatocellular carcinoma.
    Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:4

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antidotes; Antineoplastic Agents; Antineoplastic Combined

2006
A phase II trial of gemcitabine plus UFUR combination chemotherapy in non-small-cell lung cancer patients failing previous chemotherapy.
    Lung cancer (Amsterdam, Netherlands), 2006, Volume: 52, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small

2006
A phase I dose-escalation study of S-1 plus carboplatin in patients with advanced non-small-cell lung cancer.
    Anti-cancer drugs, 2007, Volume: 18, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Car

2007
Effectiveness of pharmacokinetic modulating chemotherapy combined with cisplatin as induction chemotherapy in resectable locally advanced head and neck cancer: phase II study.
    Cancer chemotherapy and pharmacology, 2008, Volume: 63, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co

2008
Long-term results of a phase II trial of high-dose radiotherapy (60 Gy) and UFT/l-leucovorin in patients with non-resectable locally advanced rectal cancer (LARC).
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Comb

2008
A phase I study of combination chemotherapy with gemcitabine and oral UFT for advanced non-small cell lung cancer.
    British journal of cancer, 2002, Jun-05, Volume: 86, Issue:11

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cel

2002

Other Studies

3 other studies available for tegafur and Blood Diseases

ArticleYear
Feasibility and toxicity of adjuvant chemotherapy using S-1 granules for local advanced squamous cell carcinoma of the head and neck.
    Journal of chemotherapy (Florence, Italy), 2015, Volume: 27, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemot

2015
Safety and efficacy of S-1 chemotherapy in recurrent/metastatic head and neck cancer.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2009, Volume: 15, Issue:5

    Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Carcinoma, Adenosquamous; Carcinoma, Sq

2009
[Risk associated with severe hematological toxicity in patients with advanced or recurrent colonic cancer receiving combination chemotherapy of S-1 and irinotecan hydrochloride].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:11

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Ch

2010