tedizolid-phosphate has been researched along with Joint-Diseases* in 1 studies
1 other study(ies) available for tedizolid-phosphate and Joint-Diseases
| Article | Year |
|---|---|
In vitro activity of tedizolid and comparator agents against Gram-positive pathogens responsible for bone and joint infections.
Tedizolid, a second-generation oxazolidinone that displays a potent activity against Gram-positive pathogens, could be an interesting option for the treatment of bone and joint infections (BJIs). The aim of the study was to determine minimal inhibitory concentration (MIC) of tedizolid against a collection of 359 clinical isolates involved in clinically-documented BJIs and to compare them to those of comparator agents used in Gram-positive infections. Of the 104 Staphylococcusaureus and 102 coagulase-negative staphylococci (CoNS) isolates, 99 and 92 % were categorized as susceptible to tedizolid, respectively (MIC25=0.12/0.25 µg ml Topics: Anti-Bacterial Agents; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Joint Diseases; Microbial Sensitivity Tests; Organophosphates; Osteomyelitis; Oxazoles | 2017 |