tedizolid has been researched along with Edema* in 1 studies
1 other study(ies) available for tedizolid and Edema
| Article | Year |
|---|---|
The anti-inflammatory effect of tedizolid on carrageenan-induced footpad edema rat model.
Tedizolid (TZD) is an oxazolidinone anti-methicillin-resistant Staphylococcus aureus (MRSA) drug. Linezolid (LZD), another oxazolidinone, has been shown to have an anti-inflammatory effect. TZD has been shown to exhibit an anti-inflammatory effect in a murine model of hematogenous pulmonary infection. In this study, we further investigated the anti-inflammatory effect of TZDs using a carrageenan-induced rat footpad edema model. TZD was administered at 0, 10, 20, and 40 mg/kg to the carrageenan-induced rat footpad edema model, and the edema rate was measured over time up to 9 h later. The area under the time curve of the edema rate profile (AUC Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Carrageenan; Edema; Methicillin-Resistant Staphylococcus aureus; Mice; Oxazolidinones; Rats | 2023 |