technetium-tc-99m-tetrofosmin has been researched along with Pheochromocytoma* in 1 studies
1 other study(ies) available for technetium-tc-99m-tetrofosmin and Pheochromocytoma
| Article | Year |
|---|---|
A case of malignant pheochromocytoma with early intense uptake and immediate rapid washout of 99mTc-tetrofosmin characterizing the overexpression of anti-apoptotic Bcl-2.
Defective apoptotic program due to the overexpression of the anti-apoptotic Bcl-2 protein of the outer mitochondrial membrane may be a cause of the poor response of malignant pheochromocytoma to 131I-MIBG therapy. We report a case of malignant pheochromocytoma which showed early intense uptake and immediate rapid washout of 99mTc-tetrofosmin characterizing the overexpression of anti-apoptotic Bcl-2 and which was refractory to 131I-MIBG therapy. Topics: Adrenal Gland Neoplasms; Aged; Apoptosis Regulatory Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Metabolic Clearance Rate; Organophosphorus Compounds; Organotechnetium Compounds; Pheochromocytoma; Proto-Oncogene Proteins c-bcl-2; Radionuclide Imaging; Radiopharmaceuticals | 2006 |