technetium-tc-99m-sulfur-colloid and Spinal-Neoplasms

Topics: Adult; Bone Marrow; Diagnosis, Differential; Hematopoiesis, Extramedullary; Humans; Male; Radionuclide Imaging; Spinal Neoplasms; Technetium Tc 99m Sulfur Colloid; Thalassemia; Tomography, X-Ray Computed

Three vertebral lesions, two compression fractures, and one metastasis in two patients, were incidentally demonstrated during Tc-99m sulfur colloid liver-spleen studies. Although the scintigraphic photon-deficient area could not be differentiated due to the metastasis and the compression fracture, the abnormal radiocolloid findings of vertebrae may lead to further studies using Tc-99m diphosphonate, Ga-67, radiographic studies, and/or biopsy.

Topics: Aged; Fractures, Bone; Fractures, Spontaneous; Humans; Liver; Male; Middle Aged; Radionuclide Imaging; Spinal Injuries; Spinal Neoplasms; Spleen; Technetium Tc 99m Sulfur Colloid

In a patient with synovial sarcoma, routine bone survey showed no abnormality, while bone marrow scintigraphy with Tc-99m sulfur colloid revealed a defect in the fifth lumbar vertebra. At surgery, tumorous invasion was noted in the fifth lumbar vertebra and the surrounding tissues. It was suggested that the bone marrow scintigraphy was particularly useful in the detection of tumorous invasion into the bone marrow at the early stage before the destruction of skeletal tissue.

Topics: Adolescent; Bone Marrow; Diphosphonates; Foot Diseases; Humans; Lumbar Vertebrae; Male; Neoplasm Metastasis; Radionuclide Imaging; Sarcoma, Synovial; Spinal Neoplasms; Technetium; Technetium Tc 99m Medronate; Technetium Tc 99m Sulfur Colloid