technetium-tc-99m-sulfur-colloid and Rhabdomyosarcoma

Radionuclide scintigraphy was performed in 46 children with rhabdomyosarcoma. Of the 63 radiologically confirmed sites of bone disease, 76% were detected by 99mTc-labeled phosphate uptake. All 15 sites of hepatic involvement and eight of the nine cranial sites of disease exhibited isotope accumulation. Gallium 67 scans showed 57% of the 43 proven sites of disease, including four previously unsuspected areas. Twelve false-positive sites were obtained with gallium. Radionuclide scanning is a valuable aid in the diagnostic evaluation and management of childhood rhabdomyosarcoma.

Topics: Adolescent; Bone Neoplasms; Child; Child, Preschool; False Positive Reactions; Female; Gallium Radioisotopes; Head and Neck Neoplasms; Humans; Infant; Infant, Newborn; Liver Neoplasms; Male; Radionuclide Imaging; Rhabdomyosarcoma; Splenic Neoplasms; Sulfur; Technetium; Technetium Tc 99m Sulfur Colloid; Urogenital Neoplasms