technetium-tc-99m-sulfur-colloid and Retroperitoneal-Neoplasms

Topics: Adolescent; Anemia, Hypochromic; Castleman Disease; Gallium Radioisotopes; Humans; Male; Radiography, Abdominal; Retroperitoneal Neoplasms; Technetium Tc 99m Sulfur Colloid; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

Although FDG PET is increasingly used for the staging of many types of sarcoma, little has been written regarding the FDG PET imaging characteristics of solitary fibrous tumor. We report a patient undergoing FDG PET/CT surveillance for squamous cell carcinoma of the tongue who was incidentally found to have two soft tissue masses in the retroperitoneum and pancreatic tail. Due to their low degree of FDG avidity, they were followed conservatively for approximately one year as they gradually increased in size. Technetium-99m sulfur colloid SPECT helped confirm that the pancreatic tail mass was not a splenule, after which both lesions were surgically resected and found to be extrathoracic solitary fibrous tumors without malignant features. These findings suggest that, as with other low-grade sarcomas, benign extrathoracic solitary fibrous tumors exhibit relatively little glycolytic metabolism in vivo.

Topics: Carcinoma, Squamous Cell; Fluorodeoxyglucose F18; Humans; Incidental Findings; Male; Middle Aged; Multimodal Imaging; Neoplasms, Multiple Primary; Pancreatic Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Retroperitoneal Neoplasms; Solitary Fibrous Tumors; Technetium Tc 99m Sulfur Colloid; Tomography, X-Ray Computed; Tongue Neoplasms

Topics: Adrenal Gland Neoplasms; Aged; Humans; Male; Myelolipoma; Radionuclide Imaging; Retroperitoneal Neoplasms; Splenomegaly; Technetium Tc 99m Sulfur Colloid; Thrombocytopenia; Tomography, X-Ray Computed

Topics: Carcinoma, Hepatocellular; Female; Gallium Radioisotopes; Ganglia, Sympathetic; Humans; Liver; Liver Neoplasms; Middle Aged; Pheochromocytoma; Radionuclide Imaging; Retroperitoneal Neoplasms; Technetium Tc 99m Sulfur Colloid

An unusual posterior extension of the right lobe of the liver mimicked a retroperitoneal mass on CT scanning. Tc-99m SC SPECT imaging documented normal liver uptake within the suspected mass, proving that it was an anomalous extension of the right lobe of the liver rather than a pathologic lesion. This unusual liver variant is not believed to have been reported previously.

Topics: Aged; Diagnosis, Differential; Female; Humans; Liver; Retroperitoneal Neoplasms; Technetium Tc 99m Sulfur Colloid; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

Nine patients with colonic carcinoma were studied with I-131-labeled F(ab')2 fragments of an anti-colorectal carcinoma monoclonal antibody. A total of 69% of colon cancer sites were detected without background subtraction; metastases from a concurrent breast carcinoma in one patient were not seen. Lesions ranged from 1.5 to 8 cm. The mean thyroid uptake of I-131 at 24 hours was 0.25%. Half-lives of I-131 in the blood (protein-bound and total) fit a two-compartment model, with half-lives of 3.5 and 27.6 hours for the protein-bound fraction and 3.6 and 23.8 hours for total I-131. Using quantitative methods, a mean value of 0.0047%/cm3 of the administered dose was localized in the tumor at peak concentration, which occurred approximately 48 hours post-administration. This has implications for therapy planning.

Topics: Antibodies, Monoclonal; Carcinoma; Colonic Neoplasms; Erythrocytes; Humans; Immunoglobulin Fab Fragments; Iodine Radioisotopes; Liver Neoplasms; Lung Neoplasms; Radionuclide Imaging; Retroperitoneal Neoplasms; Sulfur; Technetium; Technetium Tc 99m Sulfur Colloid