technetium-tc-99m-sulfur-colloid and Respiratory-Aspiration-of-Gastric-Contents

Aspiration can cause acute symptoms and chronic lung disease in the developing lung. However, the source of aspiration in infants is often unclear, making the choice of intervention difficult.. To quantify the source, amount and duration of lung aspiration in infants using gamma scintigraphy.. Two infants with clinical evidence of gastroesophageal reflux and oropharyngeal dysphagia swallowed formula radiolabeled with. Aspiration was greatest with swallowing, compared to instillation, peaking between 2.0% and 2.4% within 30 min and between 0.40% and 0.65% within 20 min, respectively. Radioactivity remained above zero four hours after either administration.. Quantification of the source, amount and duration of lung aspiration in infants is feasible using gamma scintigraphy. The impact of aspiration accrual on clinical care deserves further investigation.

Topics: Deglutition; Deglutition Disorders; Gastroesophageal Reflux; Humans; Infant; Intubation, Gastrointestinal; Male; Radionuclide Imaging; Radiopharmaceuticals; Respiratory Aspiration; Respiratory Aspiration of Gastric Contents; Technetium Tc 99m Sulfur Colloid