technetium-tc-99m-sulfur-colloid and Mediastinal-Neoplasms

Separate imaging studies employing Tc-99m MDP, In-111 labeled leukocytes, and Tc-99m SC were performed in a patient receiving external beam radiation therapy to the mediastinum and left hemithorax. The leukocyte scan demonstrated greatly increased activity at the site of the radiation port. The bone marrow (sulfur colloid) scan was normal and the bone scan demonstrated only minimally increased activity in the irradiated region. The varying appearance of these scans may represent the difference in the early effect of radiation on bone and bone marrow elements.

Topics: Bone Marrow; Carcinoma, Renal Cell; Humans; Indium Radioisotopes; Leukocytes; Male; Mediastinal Neoplasms; Middle Aged; Radionuclide Imaging; Radiotherapy, High-Energy; Ribs; Technetium Tc 99m Medronate; Technetium Tc 99m Sulfur Colloid; Thoracic Neoplasms; Thoracic Vertebrae

Topics: Humans; Lymphoma, Large B-Cell, Diffuse; Male; Mediastinal Neoplasms; Middle Aged; Radionuclide Imaging; Sclerosis; Technetium Tc 99m Sulfur Colloid

Extramedullary hematopoiesis is an infrequent cause of thoracic masses. Extrathoracic locations are even less common. We have studied two patients, one with suspected pelvic neoplasm, with technetium-99m sulfur colloid marrow image and transmission computerized tomography. This noninvasive evaluation established the diagnosis of pelvic extramedullary hematopoiesis in both. We recommend a similar diagnostic approach in patients with chronic anemia or other predisposing disease, presenting with a pelvic or abdominal mass.

Topics: Adult; Anemia, Sickle Cell; Bone Marrow; Female; Hematopoiesis; Humans; Mediastinal Neoplasms; Mediastinum; Middle Aged; Pelvic Neoplasms; Pelvis; Sulfur; Technetium; Technetium Tc 99m Sulfur Colloid; Thalassemia; Tomography, Emission-Computed

Topics: Aged; Female; Gallium Radioisotopes; Humans; Liver Neoplasms; Mediastinal Neoplasms; Plasmacytoma; Radionuclide Imaging; Sulfur; Technetium; Technetium Tc 99m Sulfur Colloid

Topics: Adult; Humans; Lymphangioma; Male; Mediastinal Neoplasms; Mediastinum; Radionuclide Imaging; Sulfur; Technetium; Technetium Tc 99m Sulfur Colloid; Wounds, Gunshot