technetium-tc-99m-sulfur-colloid and Laryngeal-Diseases

We investigated the incidence of gastroesophageal reflux by scintigraphy in patients with laryngopharyngeal symptoms and findings.. The study included 32 patients (14 males, 18 females; mean age 38 years; range 17 to 55 years) who presented with laryngopharyngeal complaints. All patients underwent routine ENT and head-neck examinations and rigid endoscopy of the larynx to determine laryngopharyngeal symptoms and findings. The presence of gastroesophageal reflux was sought by technetium 99m sulfur colloid scintigraphy.. The most common symptom was dysphagia (56%) followed by hoarseness (46%). Posterior laryngitis was the most common laryngeal finding (18 patients, 56%). Scintigraphy revealed gastroesophageal reflux in 21 patients (66%), 14 of whom (67%) had posterior laryngitis.. Patients with laryngopharyngeal symptoms and findings should be investigated with regard to gastroesophageal reflux. Scintigraphy may be a method of choice in this respect.

Topics: Adolescent; Adult; Female; Gastroesophageal Reflux; Humans; Laryngeal Diseases; Male; Middle Aged; Pharyngeal Diseases; Radionuclide Imaging; Technetium Tc 99m Sulfur Colloid; Turkey

Patients with gastroesophageal reflux (GER) present to the head and neck specialist with a myriad of nonspecific complaints that may be manifestations of pharyngoesophageal or upper airway involvement. Numerous diagnostic tests for GER have been used in the past with varying success. In the present study, gastroesophageal scintigraphy using 99mtechnetium-sulfur colloid was used to evaluate 28 patients with head and neck manifestations of GER. The role of gastroesophageal scintigraphy as an accurate and noninvasive method of detecting GER is discussed in the context of other current diagnostic modalities.

Topics: Adult; Aged; Aged, 80 and over; Female; Gastroesophageal Reflux; Humans; Laryngeal Diseases; Male; Middle Aged; Pharyngeal Diseases; Radionuclide Imaging; Technetium Tc 99m Sulfur Colloid

A method of studying lymphatic drainage of the larynx was undertaken using radioactive colloids. Sites of injection were the true and false cords, aryepiglottic folds, anterior and posterior commissure, epiglottis and arytenoid. The patient was then scanned with the gamma camera 3 to 5 hours and again 24 hours post injection. Thirty-six patients were injected and results were recorded as to previous X-ray therapy, nodal activity post scanning, ipsilateral or contralateral and distant spread, and the type of radioactive particle--99mTc labeled sulfur colloid, 99mTc microalbumin (200-800 nm diameter), and 99mTc minimicroalbumin (less than 50 nm diameter). The three radiopharmaceuticals gave similar results. Previous X-ray therapy did not alter lymphatic drainage. Of 36 patients, 23 showed nodal activity on scintiscanning: none showed any axillary nor mediastinal activity.

Topics: Carcinoma, Squamous Cell; Humans; Injections, Intralymphatic; Laryngeal Diseases; Laryngeal Neoplasms; Larynx; Lymph Nodes; Lymphoscintigraphy; Neck; Serum Albumin; Sulfur; Technetium; Technetium Tc 99m Aggregated Albumin; Technetium Tc 99m Sulfur Colloid