technetium-tc-99m-sulfur-colloid and Kidney-Diseases

The major role of nuclear medicine in clinical oncology is in tumor imaging, which includes evaluating specific organs or the entire body for the presence of tumor. Nuclear medicine studies have been used clinically in the initial evaluation of the tumor extent and in the subsequent management of the cancer patient to assess response to treatment, to detect early relapse, and to assist in making decisions concerning follow-up treatment. Technetium-99m macroaggregated albumin perfusion study for intraarterial chemotherapy has been helpful in monitoring the catheter tip, providing a map of regional perfusion at the capillary level (tumor vascularity), evaluating the degree of arteriovenous shunt in tumor bed, and optimizing division of the dose of chemotherapeutic agent when bilateral arterial catheters are used. Quantitative and serial radionuclide angiocardiography has been useful in assessing doxorubicin (Adriamycin, Adria Laboratories, Columbus, Ohio) toxicity, and 67Ga-citrate imaging has been used to monitor chemotherapy effect on lungs and kidneys. Radionuclide venography can demonstrate suspected thrombus, and the delineation of the vascular anatomy also allows proper placement of another catheter for continuous effective chemotherapy. Serial bone scans have been the primary modality to assess the response of bone metastasis to systemic therapy in breast cancer patients, and nuclear hepatic imaging may show tumor response, hepatocellular dysfunction, and cholecystitis related to chemotherapeutic agents.(ABSTRACT TRUNCATED AT 250 WORDS)

Topics: Antineoplastic Agents; Bone and Bones; Bone Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Doxorubicin; Gallium Radioisotopes; Heart Failure; Humans; Injections, Intra-Arterial; Kidney Diseases; Liver; Liver Diseases; Lung; Lung Diseases; Magnetic Resonance Spectroscopy; Neoplasms; Technetium Tc 99m Aggregated Albumin; Technetium Tc 99m Sulfur Colloid; Thrombophlebitis; Tomography, Emission-Computed

A 64-year-old patient who underwent splenectomy presented clinically with ectopic splenic tissue simulating a solid renal mass. The splenic origin of the mass was assessed by radionuclide spleen scan. Nephrectomy was avoided.

Topics: Choristoma; Diagnosis, Differential; Humans; Kidney Diseases; Male; Middle Aged; Radionuclide Imaging; Spleen; Technetium Tc 99m Sulfur Colloid

We present a case of chyluria in which the demonstration of abnormal lymphaticourinary communication was established by conventional lymphangiography. Radiocolloid lymphoscintigraphy failed to demonstrate the site of leakage, probably due to technical factors which are discussed.

Topics: Chyle; Female; Humans; Kidney Diseases; Lymphatic Diseases; Lymphography; Middle Aged; Radionuclide Imaging; Technetium Tc 99m Sulfur Colloid; Tin Compounds; Ultrasonography; Urinary Bladder; Urine

Topics: Adolescent; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Kidney Diseases; Male; Radionuclide Imaging; Technetium Tc 99m Sulfur Colloid; Urinary Bladder; Urination; Vesico-Ureteral Reflux

The authors evaluated a method of detecting urinary tract bleeding using Tc-99m sulfur colloid in a canine model.

Topics: Animals; Dogs; Hemorrhage; Kidney Diseases; Radionuclide Imaging; Technetium Tc 99m Sulfur Colloid

Visualization of Ga-67 citrate in the kidneys at 48 hours and 72 hours post injection is usually interpreted as evidence of renal pathology. In reviewing approximately 200 consecutive patients referred for gallium scans, 40 patients who also underwent liver/spleen Tc-99m sulfur colloid (SC) studies within one month of the gallium study were identified. Fourteen of these patients showed advanced hepatocellular dysfunction on the Tc-99m SC liver/spleen images. Of these 14 patients, nine had persistent renal accumulation of gallium at 48 or 72 hours. Five of these nine patients had no evidence of primary renal disease by clinical or postmortem examination and subsequent clinical information indicated that two additional patients probably had no significant renal pathology. Therefore, bilateral symmetrically increased renal uptake of gallium in patients with advanced hepatocellular disease should not necessarily be interpreted as evidence of renal pathology.

Topics: Adult; Aged; Diagnosis, Differential; Gallium Radioisotopes; Humans; Kidney; Kidney Diseases; Liver; Liver Cirrhosis, Alcoholic; Liver Diseases; Male; Middle Aged; Radionuclide Imaging; Spleen; Sulfur; Technetium; Technetium Tc 99m Sulfur Colloid; Time Factors