technetium-tc-99m-sulfur-colloid and Hyperostosis-Frontalis-Interna

Hyperostosis frontalis interna is the term used to describe the thickening of the frontal bones of the skull. This thickening of the frontal bones is accompanied by an increase in the diploic space which results in an increased quantity of hematopoietically active marrow. Increased frontal bone uptake of labeled leukocytes has been reported in this condition, and the symmetric appearance of this activity may suggest its benign etiology. We have encountered a case of hyperostosis frontalis interna in which the uptake of labeled leukocytes was asymmetric and marrow scintigraphy confirmed that the activity seen was due to marrow not infection.

Topics: Aged; Bone Marrow; Female; Frontal Bone; Humans; Hyperostosis Frontalis Interna; Indium Radioisotopes; Leukocytes; Radionuclide Imaging; Technetium Tc 99m Sulfur Colloid