technetium-tc-99m-sulfur-colloid and Fractures--Bone

Topics: Adult; Bone and Bones; Bone Marrow; Bone Marrow Examination; Bone Neoplasms; Child; Child, Preschool; Fractures, Bone; Gold Colloid, Radioactive; Humans; Indium; Infant; Infarction; Iron Radioisotopes; Organotechnetium Compounds; Osteonecrosis; Phytic Acid; Radionuclide Imaging; Technetium; Technetium Tc 99m Sulfur Colloid

Three vertebral lesions, two compression fractures, and one metastasis in two patients, were incidentally demonstrated during Tc-99m sulfur colloid liver-spleen studies. Although the scintigraphic photon-deficient area could not be differentiated due to the metastasis and the compression fracture, the abnormal radiocolloid findings of vertebrae may lead to further studies using Tc-99m diphosphonate, Ga-67, radiographic studies, and/or biopsy.

Topics: Aged; Fractures, Bone; Fractures, Spontaneous; Humans; Liver; Male; Middle Aged; Radionuclide Imaging; Spinal Injuries; Spinal Neoplasms; Spleen; Technetium Tc 99m Sulfur Colloid

A study was made of reparative osteogenesis and the content of mineral bone components in 60 patients with spiral fractures of the leg bones during treatment by transosseous osteosynthesis. The time of maximum labeled pyrophosphate accumulation was determined by a degree of the initial dislocation of fragments: in the dislocation to the cortical layer it was noted on the 42nd day, by 1/3 on the 45th day, by 2/3 on the 50th day, to the cross section on the 60th day. The demineralization of bone fragments in the dislocation to the cortical layer was 34%, by 1/2 37%, by 2/3 41% and to the cross section by 44%. The labeled sulphuric colloid accumulation by bone marrow cells was maximal in minimal dislocations and decreased with growing dislocation.

Topics: Adult; Bone and Bones; Bone Marrow; Diphosphates; Fracture Fixation, Internal; Fractures, Bone; Fractures, Closed; Humans; Leg Injuries; Middle Aged; Minerals; Orthopedic Fixation Devices; Osteogenesis; Radionuclide Imaging; Technetium; Technetium Tc 99m Pyrophosphate; Technetium Tc 99m Sulfur Colloid; Time Factors

Thirty-two patients with fractures of the limbs were studied 15-30 min following 99mtechnetium sulphur colloid injection. In 17 of the 19 patients where osteomyelitis was superimposed on the various fractures, significant uptake of sulphur colloid was noted at the fracture sites. The sensitivity for the test was 89.5%. In 12 of the 13 cases where osteomyelitis was absent, the sulphur colloid scan was negative giving a specificity of 92.3%. Hence a technetium sulphur colloid scan has shown to be a successful method for detecting osteomyelitis complicating a limb fracture.

Topics: Adult; Fractures, Bone; Humans; Leg Injuries; Male; Osteomyelitis; Radionuclide Imaging; Sulfur; Technetium; Technetium Tc 99m Sulfur Colloid