technetium-tc-99m-sulfur-colloid and Collagen-Diseases

Conventional methods for exploration of the esophagus (radiology and fibroscopy) are not sufficiently sensitive to provide a precise diagnosis of minor lesions. New techniques have been developed that enable improved evaluation of the physiopathology of gastro-esophageal reflux and other esophageal motor disorders. These include esophageal manometry, pH monitoring, the association of these two procedures, and finally scintigraphy. Manometry is the most effective method of assessing esophageal motility, and it can assist in the diagnosis of motor disorders related to reflux, of dyskinesias such as in mega-esophagus, and of collagen diseases. The most reliable method for diagnosing gastro-esophageal reflux is by means of pH monitoring. More detailed physiological and physiopathological data can be obtained by combining the two investigational methods. Scintigraphy can sometimes determine the responsibility of pulmonary disorders in the development of reflux.

Topics: Collagen Diseases; Diverticulum, Esophageal; Esophageal Diseases; Esophagogastric Junction; Esophagus; Humans; Hydrogen-Ion Concentration; Manometry; Muscular Diseases; Pressure; Radionuclide Imaging; Sulfur; Technetium; Technetium Tc 99m Sulfur Colloid