technetium-tc-99m-sulfur-colloid and Carcinoma--Adenosquamous

The role of sentinel lymph node (SLN) biopsy alone for staging of early-stage cervical cancer remains controversial. We aimed to determine the validity of this technique in women with early-stage cervical cancer.. We retrospectively reviewed women with early-stage cervical cancer who underwent SLN mapping followed by complete pelvic lymphadenectomy as part of initial surgical management from August 1997 through October 2015. All modes of surgical approach were included. Lymphatic mapping was performed using blue dye, technetium-99m sulfur colloid (Tc-99), and/or indocyanine green (ICG). We determined SLN detection rates, sensitivity and negative predictive value.. In these women with early-stage cervical cancer, SLN biopsy had very high sensitivity and negative predictive value. We believe it is time to change the standard of care for women with early-stage cervical cancer to SLN biopsy only.

Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Coloring Agents; Female; Humans; Hysterectomy; Indocyanine Green; Laparoscopy; Lymph Node Excision; Lymphatic Metastasis; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Pelvis; Predictive Value of Tests; Radiopharmaceuticals; Retrospective Studies; Robotic Surgical Procedures; Sensitivity and Specificity; Sentinel Lymph Node; Sentinel Lymph Node Biopsy; Technetium Tc 99m Sulfur Colloid; Uterine Cervical Neoplasms; Young Adult