technetium-tc-99m-sulfur-colloid and Angiomatosis

Sclerosing angiomatoid nodular transformation (SANT) is a benign, proliferative vascular lesion affecting the spleen. Few reports detailing the cross sectional and PET appearance of this lesion are available, and the lesion's behavior with ⁹⁹(m)Tc-sulfur colloid scintigraphy is previously unreported. Sclerosing nodular transformation of the spleen shows increased tracer accumulation on positron emission tomography, and a central scar-like appearance with an enhancing capsule and radiating septae on CT and MR studies that reflects the gross and histopathological features of the lesion may be visible. An understanding of this pathological finding may allow prospective recognition of the sclerosing nodular transformation of the spleen on cross sectional imaging studies.

Topics: Aged, 80 and over; Angiomatosis; Diagnosis, Differential; Humans; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Radiopharmaceuticals; Sclerosis; Splenectomy; Splenic Diseases; Technetium Tc 99m Sulfur Colloid; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

The hospital course of a patient with diffuse skeletal hemangiomatosis is presented with reference to the role of radionuclide imaging procedures in the diagnosis and evaluation of this disorder. In addition to static scans of liver, bone, and bone marrow, flow studies using Tc-99m-sulfur colloid and methylene diphosphonate (MDP) were performed.

Topics: Adult; Angiomatosis; Bone Marrow; Bone Neoplasms; Diphosphonates; Humans; Liver; Male; Radionuclide Imaging; Sulfur; Technetium; Technetium Tc 99m Medronate; Technetium Tc 99m Sulfur Colloid