technetium-tc-99m-pyrophosphate and Lymphoma

The necropsy findings of a large cell lymphoma involving only the pericardium and myocardium in a 62-year-old woman are reported. The initial presenting symptoms were heart failure followed by rapidly progressive heart block. The diagnosis of cardiac lymphoma was suggested by gallium and blood pool isotope studies, and was subsequently confirmed by operative myocardial biopsy. The clinical course was abrupt, and the patient died before therapy was instituted. While primary cardiac lymphoma is an extremely rare condition, experience in this case suggests that noninvasive isotope studies, particularly gallium and blood pool, are helpful in the diagnosis of atypical cardiomyopathy.

Topics: Diphosphates; Female; Gallium Radioisotopes; Heart Neoplasms; Humans; Lymphoma; Middle Aged; Myocardium; Necrosis; Radionuclide Imaging; Technetium; Technetium Tc 99m Pyrophosphate

Topics: Animals; Diphosphates; Iron-Dextran Complex; Lymphoma; Mice; Radionuclide Imaging; T-Lymphocytes; Technetium; Technetium Tc 99m Pyrophosphate; Tissue Distribution

To determine the scintigraphic findings in children with distal femoral defects (or subperiosteal desmoids) the authors retrospectively examined 94 sets of radiographs and technetium-99m pyrophosphate bone scans of 54 children. Twenty-four examples of distal femoral defects were identified in 19 children. Only two children demonstrate focally increased uptake of radionuclide in the distal femur. The positive bone scan was caused by osteomyelitis in one of these patients and by metastatic lymphoma in the other. None of the 17 other children with distal femoral defects on radiography had a corresponding focal increase in uptake of radionuclide. The bone scan appears to be a useful method for confirming that a distal femoral defect is benign and, when positive, indicates the presence of other disease.

Topics: Adolescent; Child; Child, Preschool; Diphosphates; Female; Femoral Neoplasms; Femur; Fibroma; Humans; Knee; Lymphoma; Osteomyelitis; Radiography; Radionuclide Imaging; Retrospective Studies; Technetium; Technetium Tc 99m Pyrophosphate

Topics: Child, Preschool; Diphosphates; Female; Humans; Jaw Neoplasms; Lymphoma; Male; Maxillary Neoplasms; Radionuclide Imaging; Technetium; Technetium Tc 99m Pyrophosphate