technetium-tc-99m-pyrophosphate and Chondrosarcoma

The diagnosis of chondrosarcoma may be difficult if there is an atypical radiographic appearance or an inconclusive biopsy. Radionuclide bone scans of 13 patients with chondrosarcoma were reviewed to assess if a pattern of scan features could be recognised in association with this tumour. A combination, including increased blood pool activity, moderate intensity of uptake, patchy uptake with cortical predominance of activity, minimal distortion of bony outline, and a well-defined scintigraphic margin, occurred regularly in the series. Recognition of this characteristic pattern of scintigraphic features in cases of suspected chondrosarcoma may assist in the diagnostic assessment.

Topics: Adolescent; Adult; Aged; Bone Neoplasms; Chondrosarcoma; Diphosphates; Diphosphonates; Female; Humans; Male; Middle Aged; Radiography; Radionuclide Imaging; Technetium; Technetium Tc 99m Medronate; Technetium Tc 99m Pyrophosphate

Topics: Adult; Bone and Bones; Bone Neoplasms; Child; Chondroma; Chondrosarcoma; Diagnosis, Differential; Diphosphates; Diphosphonates; Female; Humans; Infant; Osteosarcoma; Radionuclide Imaging; Technetium; Technetium Tc 99m Medronate; Technetium Tc 99m Pyrophosphate