technetium-tc-99m-pyrophosphate and Arthritis--Reactive

The polyetiology, the discrepancies in the initial manifestations, polymorphism in the course and the possibility of the ephemerality or absence of ocular, uro-genital and skin-mucosal manifestations create jointly the preconditions for a frequent diagnostic error in Reiter syndrome. The study confirmed the thesis that the diagnostic characteristics including the articular symptomatics are among the most striking ones. Synovial-arthritis and the involvement of the soft tissues are accompanied by disorders in the immune system with increased number of early T-lymphocytes, of Fc Gd and complement (C3b)-receptor lymphocytes and of spontaneously blast-transformed cells. The rheumatological process is characterized by proportionately accumulation of 99m Tc-pertechnetate and 99m Tc-pyrophosphate in the affected articular structures, with asymmetry of affection, with predilection and maximal capture of the radiopharmaceutical in the feet. The radioisotope information is on scanty alterations in the spine and sacroiliac joints. The complex study facilitates the timely diagnosis of the disease.

Topics: Adolescent; Adult; Arthritis; Arthritis, Reactive; Arthrography; Diphosphates; Female; Humans; Immunologic Tests; Male; Sodium Pertechnetate Tc 99m; Technetium; Technetium Tc 99m Pyrophosphate

Topics: Arthritis, Reactive; Arthritis, Rheumatoid; HLA Antigens; Humans; Prognosis; Radionuclide Imaging; Sacroiliac Joint; Sacrum; Spondylitis, Ankylosing; Technetium; Technetium Tc 99m Pyrophosphate; Tin Polyphosphates