technetium-tc-99m-pyrophosphate and Abscess

Positive results of the use of 99mTc-pyrophosphate in 91.9% of patients with pyoseptic foci of various sites prove a regular character of increased accumulation of this agent in abscesses and permit recommending this method as a screening test in their indefinite localization. If the foci are localized in the liver, positive scintigraphy should be supplemented by negative scintigraphy of the liver, increasing the diagnostic value of radionuclide methods.

Topics: Abdomen; Abscess; Adolescent; Adult; Aged; Diphosphates; False Negative Reactions; False Positive Reactions; Focal Infection; Humans; Middle Aged; Retroperitoneal Space; Technetium; Technetium Tc 99m Pyrophosphate; Tomography, Emission-Computed

Abscess imaging with leukocyte scintigraphy is described in a case report. Autologous leukocytes were separated from whole blood in a patient with localized inflammation in the perineal region and labeled with 99mTc, an ideal radionuclide for clinical examination with gamma camera. Scintigraphic investigations demonstrated a deep-lying anal abscess. The procedure may prove useful for detection of occult infections and may provide a new diagnostic approach in fever of unknown origin.

Topics: Abscess; Adult; Diphosphates; Female; Humans; Leukocytes; Proctitis; Radionuclide Imaging; Technetium; Technetium Tc 99m Pyrophosphate

The present paper compares scintigraphy using leucocytes labelled with 111 indium oxine sulphate with conventional 99Tc pyrophosphate scintigraphy for the investigation of inflammatory processes in the region of the jaw bones. It also tries to establish whether progress can be made in the field of differential diagnosis using a combination of these two methods of investigation. It is shown that conventional scintigraphy using 99Tc pyrophosphate represents an approved method of investigation, whereas scintigraphy using autologous leucocytes does not as yet fulfil the expectations that have been placed in it.

Topics: Abscess; Bone Cysts; Diphosphates; Granulocytes; Humans; Hydroxyquinolines; Indium; Jaw Diseases; Maxillary Sinus; Organometallic Compounds; Oxyquinoline; Radionuclide Imaging; Sinusitis; Technetium; Technetium Tc 99m Pyrophosphate

We reviewed the technetium phosphate scans of 280 patients who had been referred with a clinical diagnosis of osteomyelitis in order to establish the diagnostic accuracy of this procedure. Strict criteria were established to define two subgroups: one of patients with proved osteomyelitis and one of patients who definitely did not have osteomyelitis. The scan correctly identified osteomyelitis at fifty-five of sixty-two sites, and was correctly negative in seventy-four of seventy-nine patients without osteomyelitis. The scan correctly distinguished all cases of cellulitis or soft-tissue abscess from osteomyelitis, but identified osteomyelitis in eight of thirty-nine patients with septic arthritis. The phosphate bone scan maintained this accuracy through any duration of symptoms, and performed almost equally well at all skeletal sites and in all age groups.

Topics: Abscess; Adolescent; Bone and Bones; Cellulitis; Child; Child, Preschool; Diagnosis, Differential; Diphosphates; Diphosphonates; Humans; Infant; Osteomyelitis; Radionuclide Imaging; Technetium; Technetium Tc 99m Medronate; Technetium Tc 99m Pyrophosphate