technetium-tc-99m-medronate and Tongue-Neoplasms

Classical appearance of "Lincoln's sign" on 99mTc-MDP bone scintigraphy has been described in literature in case of monostotic Paget disease of mandible showing increased radiotracer uptake in the body of mandible. This pattern has also been described as "black beard" sign. The monostotic presentation of Paget disease is rare, and involving the mandible, however, is very unusual. We present a case of carcinoma of the tongue with contiguous spread to the mandible presented in the similar fashion as the earlier reported Lincoln's sign or black beard sign on 99mTc-MDP bone scintigraphy. This appearance was confirmed with SPECT/CT, and the lytic sclerotic lesion of the mandible was confirmed.

Topics: Bone and Bones; Bone Neoplasms; Humans; Male; Middle Aged; Radiography; Radionuclide Imaging; Technetium Tc 99m Medronate; Tongue Neoplasms

Skeletal scintigraphy, a sensitive diagnostic tool used to detect changes in bone, is helpful for evaluating bone invasion by oral cancer. However, the exact sites of accumulation of 99mTc-phosphate compounds in the mandible have not yet been fully elucidated. The aim of this study was to determine the localization of 99mTc-methylene diphosphonate (MDP) in the areas of mandible that have been invaded by cancer.. Seven patients with oral cancer (lower gingiva, 4; tongue, 2; floor of the mouth, 1) who underwent surgical treatment with mandibular bone resection were included in the study. Autoradiography and contact macroradiography were used for evaluation of 99mTc-MDP accumulation.. Radioactivity reflecting accumulation of 99mTc-MDP was documented encircling the portion of the mandible with cancerous invasion, suggesting that 99mTc-MDP accumulated in immature bone. High uptake also was found in the periosteal reactive bone around the cortical bone.. The amount of increased 99mTc-MDP circumscribing carcinoma invasion varies among cases. Additionally, uptake may not correspond directly with the amount of the carcinoma invasion; that seen in periosteal bone could be attributed mistakenly to bone invasion in planar scintigraphy.

Topics: Aged; Alveolar Process; Autoradiography; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Female; Gingival Neoplasms; Humans; Male; Mandibular Neoplasms; Middle Aged; Mouth Floor; Neoplasm Invasiveness; Radionuclide Imaging; Technetium Tc 99m Medronate; Tongue Neoplasms

Topics: Aged; Biopsy; Carcinoma, Squamous Cell; Humans; Male; Muscle, Skeletal; Paraneoplastic Syndromes; Polymyositis; Radionuclide Imaging; Technetium Tc 99m Medronate; Tongue Neoplasms

The decision of whether to perform continuity-sparing or resecting surgery of the jaw in cases of malignant oral tumors is often difficult.. To aid in this decision, bone scintigraphy was evaluated retrospectively in 304 patients with a squamous cell carcinoma.. One hundred forty-five patients showed no accumulation of the radionuclide, and none of them had infiltration by tumor histologically.. It was concluded that a bone-sparing resection of tumors close to the jaw may be justified when there is a negative bone scan.

Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Cheek; Child; Diphosphonates; False Negative Reactions; Female; Humans; Jaw Neoplasms; Lip Neoplasms; Male; Middle Aged; Mouth Floor; Mouth Neoplasms; Organotechnetium Compounds; Patient Care Planning; Predictive Value of Tests; Radiography; Radionuclide Imaging; Retrospective Studies; Technetium Tc 99m Medronate; Tongue Neoplasms